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Publications indexed to the term Gene Expression Regulation

FacultyTitle
1Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression. (Kim J, Hwang Y, Kim S, Kwon D, Park J, Cho B, An S, Kang S, Kim Y, Kim S, Lengner CJ, Kim S, Kwon Y, Sung JS, Kim J) Cell 2026 May 28;189(11):3465-3480.e23    
1Myogenic Differentiation (MyoD) Gene Expression in Cornea and Role in Corneal Myofibroblast Dedifferentiation. (Tripathi R, Sinha NR, Sood S, Gupta S, Kumar R, Sinha PR, Balne PK, Chaurasia SS, Ghosh A, Mohan RR) Invest Ophthalmol Vis Sci 2026 Mar 02;67(3):7    
1Whole Blood Transcriptomic Analysis of Sickle Cell Trait. (Johnson M, Cai Y, Vasconcelos AG, Orchard P, Auer PL, Lettre G, Wen J, Franceschini N, Kooperberg C, Sun W, Hsu L, Raffield LM, Reiner AP) Eur J Haematol 2026 May;116(5):535-544    
1Beyond transcription: RNA-binding proteins steering angiogenesis. (Hamm K, Clifford E, Kozak KN, Cullison J, Iqbal H, Yan R, Xing Y, Liu Z) Am J Physiol Heart Circ Physiol 2026 Jan 01;330(1):H288-H304       1 Citation
1Lipopolysaccharide-induced cytokine signaling activates a temporal innate defense program and represses pancreatic β-cell identity. (Bartosiak JT, Hansen PA, Schumacher EA, Harty KR, Stancill JS, Corbett JA) J Biol Chem 2025 Dec;301(12):110811    
2Chromatin interaction maps of human arterioles reveal mechanisms for the genetic regulation of blood pressure. (Liu Y, Pandey R, Qiu Q, Liu P, Xue H, Wang J, Therani B, Ying R, Usa K, Grzybowski M, Yang C, Mishra MK, Greene AS, Cowley AW Jr, Rao S, Geurts AM, Widlansky ME, Liang M) Nat Commun 2025 Jul 17;16(1):6577       1 Citation
2Cullin-3 regulates the renal baroreceptor machinery that controls renin gene expression. (Golosova D, Kumar G, Lu KT, Muskus Veitia PC, Hantke Guixa A, Wackman KK, Fekete EM, Brozoski DT, Grobe JL, Sequeira-Lopez MLS, Gomez RA, Nakagawa P, Sigmund CD) JCI Insight 2025 Aug 08;10(15)    
1Inflammatory metabolite 7α,25-OHC promotes TIMP1 expression in COVID-19 monocytes through synergy effect of SMARCC1/JUND/H3K27ac. (Feng Y, Wu Z, Hu K, Yuan S, Li J, Wang Y, Wang Z, Yang H, Luo ZH, Zhou J) Cell Mol Life Sci 2025 May 21;82(1):208    
2Molecular inflammatory expression profiles associated with the frequency of pain in individuals with sickle cell disease. (Mucalo Katunaric L, Jia S, Singh A, Roethle MF, Panepinto JA, Brousseau DC, Hessner MJ, Brandow AM) Blood Adv 2025 Aug 12;9(15):3790-3800       1 Citation
1Conserved chromatin regulators control the transcriptional immune response to intracellular pathogens in Caenorhabditis elegans. (Tecle E, Warushavithana P, Li S, Blanchard MJ, Chhan CB, Bui T, Underwood RS, Bakowski MA, Troemel ER, Lažetić V) PLoS Genet 2025 Apr;21(4):e1011444       2 Citations
2Role of SIRT3 in the regulation of Gadd45α expression and DNA repair in β-cells. (Naatz A, Bohl KS, Jones Lipinski RA, Nord JA, Gehant AL, Hansen PA, Smith BC, Corbett JA) J Biol Chem 2025 May;301(5):108451    
1A novel L-RNA aptamer to regulate the pUG fold RNA-induced gene expression in vivo. (Liew SW, Cao D, Petersen RJ, Butcher SE, Kennedy SG, Kwok CK) Nucleic Acids Res 2025 Feb 27;53(5)       3 Citations
2Cardiac dysfunction and altered gene expression in acid ceramidase-deficient mice. (Kleynerman A, Rybova J, McKillop WM, Dlugi TA, Faber ML, Fuller M, O'Meara CC, Medin JA) Am J Physiol Heart Circ Physiol 2025 Jan 01;328(1):H141-H156       3 Citations
2A De Novo Noncoding RARB Variant Associated with Complex Microphthalmia Alters a Putative Regulatory Element. (Replogle MR, Thompson S, Reis LM, Semina EV) Hum Mutat 2024;2024       4 Citations
1Identification of shared gene expression programs activated in multiple modes of torpor across vertebrate clades. (Weir K, Vega N, Busa VF, Sajdak B, Kallestad L, Merriman D, Palczewski K, Carroll J, Blackshaw S) Sci Rep 2024 Oct 17;14(1):24360       3 Citations
1An efficient inducible model for the control of gene expression in renin cells. (Medrano S, Yamaguchi M, Almeida LF, Smith JP, Yamaguchi H, Sigmund CD, Sequeira-Lopez MLS, Gomez RA) Am J Physiol Renal Physiol 2024 Sep 01;327(3):F489-F503       2 Citations
1Histone oxidation as a new mechanism of metabolic control over gene expression. (Gantner BN, Palma FR, Kayzuka C, Lacchini R, Foltz DR, Backman V, Kelleher N, Shilatifard A, Bonini MG) Trends Genet 2024 Sep;40(9):739-746       13 Citations
1Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes. (Keener R, Chhetri SB, Connelly CJ, Taub MA, Conomos MP, Weinstock J, Ni B, Strober B, Aslibekyan S, Auer PL, Barwick L, Becker LC, Blangero J, Bleecker ER, Brody JA, Cade BE, Celedon JC, Chang YC, Cupples LA, Custer B, Freedman BI, Gladwin MT, Heckbert SR, Hou L, Irvin MR, Isasi CR, Johnsen JM, Kenny EE, Kooperberg C, Minster RL, Naseri T, Viali S, Nekhai S, Pankratz N, Peyser PA, Taylor KD, Telen MJ, Wu B, Yanek LR, Yang IV, Albert C, Arnett DK, Ashley-Koch AE, Barnes KC, Bis JC, Blackwell TW, Boerwinkle E, Burchard EG, Carson AP, Chen Z, Chen YI, Darbar D, de Andrade M, Ellinor PT, Fornage M, Gelb BD, Gilliland FD, He J, Islam T, Kaab S, Kardia SLR, Kelly S, Konkle BA, Kumar R, Loos RJF, Martinez FD, McGarvey ST, Meyers DA, Mitchell BD, Montgomery CG, North KE, Palmer ND, Peralta JM, Raby BA, Redline S, Rich SS, Roden D, Rotter JI, Ruczinski I, Schwartz D, Sciurba F, Shoemaker MB, Silverman EK, Sinner MF, Smith NL, Smith AV, Tiwari HK, Vasan RS, Weiss ST, Williams LK, Zhang Y, Ziv E, Raffield LM, Reiner AP, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, TOPMed Structural Variation Working Group, Arvanitis M, Greider CW, Mathias RA, Battle A) Nat Commun 2024 May 24;15(1):4417       6 Citations
1Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells. (Okumura T, Raja Xavier JP, Pasternak J, Yang Z, Hang C, Nosirov B, Singh Y, Admard J, Brucker SY, Kommoss S, Takeda S, Staebler A, Lang F, Salker MS) Int J Mol Sci 2024 Mar 25;25(7)       7 Citations
2β-Cell-selective regulation of gene expression by nitric oxide. (Naatz A, Yeo CT, Hogg N, Corbett JA) Am J Physiol Regul Integr Comp Physiol 2024 Jun 01;326(6):R552-R566       6 Citations
1The emerging role of epitranscriptome in shaping stress responses in plants. (Dhingra Y, Gupta S, Gupta V, Agarwal M, Katiyar-Agarwal S) Plant Cell Rep 2023 Oct;42(10):1531-1555       12 Citations
4FOXM1 regulates glycolysis and energy production in multiple myeloma. (Cheng Y, Sun F, Thornton K, Jing X, Dong J, Yun G, Pisano M, Zhan F, Kim SH, Katzenellenbogen JA, Katzenellenbogen BS, Hari P, Janz S) Oncogene 2022 Aug;41(32):3899-3911       46 Citations
1Methods for Isolating and Defining Single-Cell Transcriptomes of Tissue-Resident Human NK Cells. (Hashemi E, Mei A, Wang D, Khalil M, Malarkannan S) Methods Mol Biol 2022;2463:103-116    
1Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice. (Fang K, Liu D, Pathak SS, Yang B, Li J, Karthikeyan R, Chao OY, Yang YM, Jin VX, Cao R) Cells 2021 Nov 26;10(12)       22 Citations
1Biological features between miRNAs and their targets are unveiled from deep learning models. (Gu T, Xie M, Barbazuk WB, Lee JH) Sci Rep 2021 Dec 10;11(1):23825       9 Citations
1Laboratory methods to decipher epigenetic signatures: a comparative review. (Halabian R, Valizadeh Arshad, Ahmadi A, Saeedi P, Azimzadeh Jamalkandi S, Alivand MR) Cell Mol Biol Lett 2021 Nov 11;26(1):46       24 Citations
1Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases. (Georges A, Yang ML, Berrandou TE, Bakker MK, Dikilitas O, Kiando SR, Ma L, Satterfield BA, Sengupta S, Yu M, Deleuze JF, Dupré D, Hunker KL, Kyryachenko S, Liu L, Sayoud-Sadeg I, Amar L, Brummett CM, Coleman DM, d'Escamard V, de Leeuw P, Fendrikova-Mahlay N, Kadian-Dodov D, Li JZ, Lorthioir A, Pappaccogli M, Prejbisz A, Smigielski W, Stanley JC, Zawistowski M, Zhou X, Zöllner S, FEIRI investigators, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group, MEGASTROKE, Amouyel P, De Buyzere ML, Debette S, Dobrowolski P, Drygas W, Gornik HL, Olin JW, Piwonski J, Rietzschel ER, Ruigrok YM, Vikkula M, Warchol Celinska E, Januszewicz A, Kullo IJ, Azizi M, ARCADIA Investigators, Jeunemaitre X, Persu A, Kovacic JC, Ganesh SK, Bouatia-Naji N) Nat Commun 2021 Oct 15;12(1):6031       55 Citations
1The Role of microRNAs in NK Cell Development and Function. (Nanbakhsh A, Malarkannan S) Cells 2021 Aug 07;10(8)       14 Citations
1Assessment of Expression of SOCS Genes in Acquired Immune-Mediated Polyneuropathies. (Taheri M, Sangseifid S, Shahani P, Eftekharian MM, Arsang-Jang S, Ghafouri-Fard S) Front Immunol 2021;12:712859       2 Citations
2Role of GATA2 in Human NK Cell Development. (Wang D, Uyemura B, Hashemi E, Bjorgaard S, Riese M, Verbsky J, Thakar MS, Malarkannan S) Crit Rev Immunol 2021;41(2):21-33       9 Citations
1A Cre-Dependent CRISPR/dCas9 System for Gene Expression Regulation in Neurons. (Carullo NVN, Hinds JE, Revanna JS, Tuscher JJ, Bauman AJ, Day JJ) eNeuro 2021;8(4)       18 Citations
2Cardiomyocyte-produced miR-339-5p mediates pathology in Duchenne muscular dystrophy cardiomyopathy. (Gartz M, Beatka M, Prom MJ, Strande JL, Lawlor MW) Hum Mol Genet 2021 Nov 16;30(23):2347-2361       16 Citations
1Expression Analysis of VDR-Related LncRNAs in Autism Spectrum Disorder. (Ghafouri-Fard S, Eghtedarian R, Hussen BM, Motevaseli E, Arsang-Jang S, Taheri M) J Mol Neurosci 2021 Jul;71(7):1403-1409       12 Citations
1E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation. (Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W) Proc Natl Acad Sci U S A 2021 Apr 20;118(16)       30 Citations
1Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain. (Wang SM, Goguadze N, Kimura Y, Yasui Y, Pan B, Wang TY, Nakamura Y, Lin YT, Hogan QH, Wilson KL, Su TP, Wu HE) Mol Neurobiol 2021 Jun;58(6):2523-2541       17 Citations
1Glutathione is a potential therapeutic target for acrolein toxicity in the cornea. (Gupta S, Kamil S, Sinha PR, Rodier JT, Chaurasia SS, Mohan RR) Toxicol Lett 2021 Apr 01;340:33-42       23 Citations
2Donor-specific phenotypic variation in hiPSC cardiomyocyte-derived exosomes impacts endothelial cell function. (Turner A, Aggarwal P, Matter A, Olson B, Gu CC, Hunt SC, Lewis CE, Arnett DK, Lorier R, Broeckel U) Am J Physiol Heart Circ Physiol 2021 Mar 01;320(3):H954-H968       16 Citations
1Genome editing demonstrates that the -5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment. (Agrawal P, Blinka S, Pulakanti K, Reimer MH Jr, Stelloh C, Meyer AE, Rao S) J Biol Chem 2021;296:100189       13 Citations
2Toll-Like Receptor 7 Is Required for Lacrimal Gland Autoimmunity and Type 1 Diabetes Development in Male Nonobese Diabetic Mice. (Debreceni IL, Chimenti MS, Serreze DV, Geurts AM, Chen YG, Lieberman SM) Int J Mol Sci 2020 Dec 13;21(24)       17 Citations
1Expression of GM-CSF Is Regulated by Fli-1 Transcription Factor, a Potential Drug Target. (Wang X, Lennard Richard M, Li P, Henry B, Schutt S, Yu XZ, Fan H, Zhang W, Gilkeson G, Zhang XK) J Immunol 2021 Jan 01;206(1):59-66       15 Citations
2Myh6-driven Cre recombinase activates the DNA damage response and the cell cycle in the myocardium in the absence of loxP sites. (Wang X, Lauth A, Wan TC, Lough JW, Auchampach JA) Dis Model Mech 2020 Dec 18;13(12)       18 Citations
1Expression of NF-κB associated lncRNAs in schizophrenia. (Safa A, Badrlou E, Arsang-Jang S, Sayad A, Taheri M, Ghafouri-Fard S) Sci Rep 2020 Oct 22;10(1):18105       23 Citations
1Biphasic effect of metformin on human cardiac energetics. (Emelyanova L, Bai X, Yan Y, Bosnjak ZJ, Kress D, Warner C, Kroboth S, Rudic T, Kaushik S, Stoeckl E, Ross GR, Rizvi F, Tajik AJ, Jahangir A) Transl Res 2021 Mar;229:5-23       35 Citations
1Transcription Factor Bhlhe40 in Immunity and Autoimmunity. (Cook ME, Jarjour NN, Lin CC, Edelson BT) Trends Immunol 2020 Nov;41(11):1023-1036       105 Citations
2CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation. (Shapiro MR, Yeh WI, Longfield JR, Gallagher J, Infante CM, Wellford S, Posgai AL, Atkinson MA, Campbell-Thompson M, Lieberman SM, Serreze DV, Geurts AM, Chen YG, Brusko TM) Front Immunol 2020;11:2180       27 Citations
1TRPswitch-A Step-Function Chemo-optogenetic Ligand for the Vertebrate TRPA1 Channel. (Lam PY, Thawani AR, Balderas E, White AJP, Chaudhuri D, Fuchter MJ, Peterson RT) J Am Chem Soc 2020 Oct 14;142(41):17457-17468       38 Citations
1Peroxynitrite-induced conformational changes in DNA that lead to cell death: UV, CD spectral, molecular dynamics simulation and FACS analysis. (Anushree G, Aravind P, Vinod D, Hemalatha N, Girisha ST, Devaraju KS) Nucleosides Nucleotides Nucleic Acids 2021;40(1):1-15       4 Citations
2Germline IKAROS dimerization haploinsufficiency causes hematologic cytopenias and malignancies. (Kuehn HS, Niemela JE, Stoddard J, Mannurita SC, Shahin T, Goel S, Hintermeyer M, Heredia RJ, Garofalo M, Lucas L, Singh S, Tondo A, Jacobs Z, Gahl WA, Latour S, Verbsky J, Routes J, Cunningham-Rundles C, Boztug K, Gambineri E, Fleisher TA, Chandrakasan S, Rosenzweig SD) Blood 2021 Jan 21;137(3):349-363       52 Citations
1Inflammation Drives MicroRNAs to Limit Hepatocyte Bile Acid Transport in Murine Biliary Atresia. (Azeltine MW, Chavez EJ, Nemec KM, Bednarek JM, Asokan R, Balasubramaniyan N, Zgheib C, Mack CL, Roach JP) J Surg Res 2020 Dec;256:663-672       13 Citations
1Pregnancy Protects Hyperandrogenemic Female Rats From Postmenopausal Hypertension. (Shawky NM, Patil CN, Dalmasso C, Maranon RO, Romero DG, Drummond H, Reckelhoff JF) Hypertension 2020 Sep;76(3):943-952       12 Citations
1Dysregulation of NF-κB-Associated lncRNAs in Multiple Sclerosis Patients. (Safa A, Arsang-Jang S, Taheri M, Omrani MD, Ghafouri-Fard S) J Mol Neurosci 2021 Jan;71(1):80-88       19 Citations
1Discovering How Heme Controls Genome Function Through Heme-omics. (Liao R, Zheng Y, Liu X, Zhang Y, Seim G, Tanimura N, Wilson GM, Hematti P, Coon JJ, Fan J, Xu J, Keles S, Bresnick EH) Cell Rep 2020 Jun 30;31(13):107832       24 Citations
1Development of an endothelial cell-restricted transgenic reporter rat: a resource for physiological studies of vascular biology. (Alexeyev M, Geurts AM, Annamdevula NS, Francis CM, Leavesley SJ, Rich TC, Taylor MS, Lin MT, Balczon R, Knighten JM, Alvarez DF, Stevens T) Am J Physiol Heart Circ Physiol 2020 Aug 01;319(2):H349-H358       4 Citations
1Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance. (Numata A, Kwok HS, Zhou QL, Li J, Tirado-Magallanes R, Angarica VE, Hannah R, Park J, Wang CQ, Krishnan V, Rajagopalan D, Zhang Y, Zhou S, Welner RS, Osato M, Jha S, Bohlander SK, Göttgens B, Yang H, Benoukraf T, Lough JW, Bararia D, Tenen DG) Blood 2020 Oct 08;136(15):1735-1747       32 Citations
3Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature. (Yang C, Siebert JR, Burns R, Zheng Y, Mei A, Bonacci B, Wang D, Urrutia RA, Riese MJ, Rao S, Carlson KS, Thakar MS, Malarkannan S) Elife 2020 May 14;9       22 Citations
1Improvement of steatotic rat liver function with a defatting cocktail during ex situ normothermic machine perfusion is not directly related to liver fat content. (Raigani S, Carroll C, Griffith S, Pendexter C, Rosales I, Deirawan H, Beydoun R, Yarmush M, Uygun K, Yeh H) PLoS One 2020;15(5):e0232886       21 Citations
4H+/K+ATPase Expression in the Larynx of Laryngopharyngeal Reflux and Laryngeal Cancer Patients. (McCormick CA, Samuels TL, Battle MA, Frolkis T, Blumin JH, Bock JM, Wells C, Yan K, Altman KW, Johnston N) Laryngoscope 2021 Jan;131(1):130-135       18 Citations
1Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling. (Shen H, Gan P, Wang K, Darehzereshki A, Wang K, Kumar SR, Lien CL, Patterson M, Tao G, Sucov HM) Elife 2020 Mar 13;9       40 Citations
1Eosinophil accumulation in postnatal lung is specific to the primary septation phase of development. (Loffredo LF, Coden ME, Jeong BM, Walker MT, Anekalla KR, Doan TC, Rodriguez R, Browning M, Nam K, Lee JJ, Abdala-Valencia H, Berdnikovs S) Sci Rep 2020 Mar 10;10(1):4425       29 Citations
1Novel Hemizygous IL2RG p.(Pro58Ser) Mutation Impairs IL-2 Receptor Complex Expression on Lymphocytes Causing X-Linked Combined Immunodeficiency. (Tuovinen EA, Grönholm J, Öhman T, Pöysti S, Toivonen R, Kreutzman A, Heiskanen K, Trotta L, Toiviainen-Salo S, Routes JM, Verbsky J, Mustjoki S, Saarela J, Kere J, Varjosalo M, Hänninen A, Seppänen MRJ) J Clin Immunol 2020 Apr;40(3):503-514       18 Citations
2The location of sensing determines the pancreatic β-cell response to the viral mimetic dsRNA. (Shaheen ZR, Stafford JD, Voss MG, Oleson BJ, Stancill JS, Corbett JA) J Biol Chem 2020 Feb 21;295(8):2385-2397       7 Citations
3Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. (Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL) Hypertension 2020 Feb;75(2):569-579       27 Citations
1Expression, localization, and functional properties of inwardly rectifying K+ channels in the kidney. (Manis AD, Hodges MR, Staruschenko A, Palygin O) Am J Physiol Renal Physiol 2020 Feb 01;318(2):F332-F337       28 Citations
1Expression Levels of lncRNAs in the Patients with the Renal Transplant Rejection. (Nafar M, Kalantari S, Ghaderian SMH, Omrani MD, Fallah H, Arsang-Jang S, Abbasi T, Samavat S, Dalili N, Taheri M, Ghafouri-Fard S) Urol J 2019 Dec 24;16(6):572-577       14 Citations
1Dysregulation of autophagy-related lncRNAs in peripheral blood of coronary artery disease patients. (Ebadi N, Ghafouri-Fard S, Taheri M, Arsang-Jang S, Parsa SA, Omrani MD) Eur J Pharmacol 2020 Jan 15;867:172852       18 Citations
1Closing the loop on cohesin in hematopoiesis. (Rao S) Blood 2019 Dec 12;134(24):2123-2125       5 Citations
2Prophylactic supplementation of 20-HETE ameliorates hypoxia/reoxygenation injury in pulmonary vascular endothelial cells by inhibiting apoptosis. (Sugumaran P, Narayanan V, Zhu D, Medhora M, Jacobs ER, Chandramohan Y, Selvaraj V, Dhanasekaran A) Acta Histochem 2020 Jan;122(1):151461       12 Citations
1Genome editing of HBG1 and HBG2 to induce fetal hemoglobin. (Métais JY, Doerfler PA, Mayuranathan T, Bauer DE, Fowler SC, Hsieh MM, Katta V, Keriwala S, Lazzarotto CR, Luk K, Neel MD, Perry SS, Peters ST, Porter SN, Ryu BY, Sharma A, Shea D, Tisdale JF, Uchida N, Wolfe SA, Woodard KJ, Wu Y, Yao Y, Zeng J, Pruett-Miller S, Tsai SQ, Weiss MJ) Blood Adv 2019 Nov 12;3(21):3379-3392       152 Citations
1Brainstem serotonergic, catecholaminergic, and inflammatory adaptations during chronic hypercapnia in goats. (Burgraff NJ, Neumueller SE, Buchholz KJ, LeClaire J, Hodges MR, Pan L, Forster HV) FASEB J 2019 Dec;33(12):14491-14505       9 Citations
2Genome-wide differential expression profiling of lncRNAs and mRNAs associated with early diabetic cardiomyopathy. (Pant T, Dhanasekaran A, Bai X, Zhao M, Thorp EB, Forbess JM, Bosnjak ZJ, Ge ZD) Sci Rep 2019 Oct 25;9(1):15345       28 Citations
1Neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy. (Gupta K, Schnell E) PLoS One 2019;14(10):e0215789       17 Citations
1The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4. (Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R) Neuron 2019 Nov 20;104(4):724-735.e6       65 Citations
1Bone Marrow Stromal Cells Transcriptionally Repress ESR1 but Cannot Overcome Constitutive ESR1 Mutant Activity. (Lung DK, Warrick JW, Hematti P, Callander NS, Mark CJ, Miyamoto S, Alarid ET) Endocrinology 2019 Oct 01;160(10):2427-2440       7 Citations
1Multigenerational epigenetic inheritance: One step forward, two generations back. (Tuscher JJ, Day JJ) Neurobiol Dis 2019 Dec;132:104591       52 Citations
1A single-cell transcriptome atlas of the adult human retina. (Lukowski SW, Lo CY, Sharov AA, Nguyen Q, Fang L, Hung SS, Zhu L, Zhang T, Grünert U, Nguyen T, Senabouth A, Jabbari JS, Welby E, Sowden JC, Waugh HS, Mackey A, Pollock G, Lamb TD, Wang PY, Hewitt AW, Gillies MC, Powell JE, Wong RC) EMBO J 2019 Sep 16;38(18):e100811       251 Citations
1Suppressor of cytokine signaling genes in renal transplant receivers: Association with transplant fate. (Nafar M, Kalantari S, Omrani MD, Samavat S, Arsang-Jang S, Taheri M, Ghafouri-Fard S) Transpl Immunol 2019 Oct;56:101228       1 Citation
1ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic β-cells. (Han EH, Singh P, Lee IK, Urrutia R, Chi YI) J Biol Chem 2019 Sep 20;294(38):13983-13994       10 Citations
1Transcriptional Regulation of Zinc Transporters in Human Osteogenic Sarcoma (Saos-2) Cells to Zinc Supplementation and Zinc Depletion. (Alluri K, Nair KPM, Kotturu SK, Ghosh S) Biol Trace Elem Res 2020 Apr;194(2):360-367       7 Citations
1Fumarase Overexpression Abolishes Hypertension Attributable to endothelial NO synthase Haploinsufficiency in Dahl Salt-Sensitive Rats. (Xue H, Geurts AM, Usa K, Wang F, Lin Y, Phillips J, Henderson L, Baker MA, Tian Z, Liang M) Hypertension 2019 Aug;74(2):313-322       14 Citations
1An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium. (Yang H, Qin X, Wang H, Zhao X, Liu Y, Wo HT, Liu C, Nishiga M, Chen H, Ge J, Sayed N, Abilez OJ, Ding D, Heilshorn SC, Li K) ACS Nano 2019 Sep 24;13(9):9880-9894       128 Citations
1Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. (Clijsters L, Hoencamp C, Calis JJA, Marzio A, Handgraaf SM, Cuitino MC, Rosenberg BR, Leone G, Pagano M) Mol Cell 2019 Jun 20;74(6):1264-1277.e7       94 Citations
1Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. (Cuitiño MC, Pécot T, Sun D, Kladney R, Okano-Uchida T, Shinde N, Saeed R, Perez-Castro AJ, Webb A, Liu T, Bae SI, Clijsters L, Selner N, Coppola V, Timmers C, Ostrowski MC, Pagano M, Leone G) Cell Rep 2019 Jun 18;27(12):3547-3560.e5       51 Citations
1Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity. (Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Lin CC, Huang SC, Lai CW, Cook ME, Taneja R, Stappenbeck TS, Randolph GJ, Artyomov MN, Urban JF Jr, Edelson BT) Nat Immunol 2019 Jun;20(6):687-700       64 Citations
1Effect of pomegranate seed oil supplementation on the GLUT-4 gene expression and glycemic control in obese people with type 2 diabetes: A randomized controlled clinical trial. (Khajebishak Y, Payahoo L, Alivand M, Hamishehkar H, Mobasseri M, Ebrahimzadeh V, Alipour M, Alipour B) J Cell Physiol 2019 Nov;234(11):19621-19628       49 Citations
1Lessons learned from a lncRNA odyssey for two genes with vascular functions, DLL4 and TIE1. (Chowdhury TA, Li K, Ramchandran R) Vascul Pharmacol 2019 Mar;114:103-109       4 Citations
1A Neuron-Optimized CRISPR/dCas9 Activation System for Robust and Specific Gene Regulation. (Savell KE, Bach SV, Zipperly ME, Revanna JS, Goska NA, Tuscher JJ, Duke CG, Sultan FA, Burke JN, Williams D, Ianov L, Day JJ) eNeuro 2019;6(1)       105 Citations
3Mapping genetic modifiers of radiation-induced cardiotoxicity to rat chromosome 3. (Schlaak RA, Frei A, Schottstaedt AM, Tsaih SW, Fish BL, Harmann L, Liu Q, Gasperetti T, Medhora M, North PE, Strande JL, Sun Y, Rui H, Flister MJ, Bergom C) Am J Physiol Heart Circ Physiol 2019 Jun 01;316(6):H1267-H1280       37 Citations
1CCR5 is a required signaling receptor for macrophage expression of inflammatory genes in response to viral double-stranded RNA. (Shaheen ZR, Christmann BS, Stafford JD, Moran JM, Buller RML, Corbett JA) Am J Physiol Regul Integr Comp Physiol 2019 May 01;316(5):R525-R534       24 Citations
1Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation. (Somineni HK, Venkateswaran S, Kilaru V, Marigorta UM, Mo A, Okou DT, Kellermayer R, Mondal K, Cobb D, Walters TD, Griffiths A, Noe JD, Crandall WV, Rosh JR, Mack DR, Heyman MB, Baker SS, Stephens MC, Baldassano RN, Markowitz JF, Dubinsky MC, Cho J, Hyams JS, Denson LA, Gibson G, Cutler DJ, Conneely KN, Smith AK, Kugathasan S) Gastroenterology 2019 Jun;156(8):2254-2265.e3       117 Citations
1Expression Analysis of BDNF Gene and BDNF-AS Long Noncoding RNA in Whole Blood Samples of Multiple Sclerosis Patients: Not Always a Negative Correlation between Them. (Gharzi V, Gangi M, Sayad A, Mazdeh M, Arsang-Jang S, Taheri M) Iran J Allergy Asthma Immunol 2018 Dec 04;17(6):548-556       10 Citations
1Expression Pattern of Long Non-coding RNAs in Schizophrenic Patients. (Safari MR, Komaki A, Arsang-Jang S, Taheri M, Ghafouri-Fard S) Cell Mol Neurobiol 2019 Mar;39(2):211-221       46 Citations
1Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. (Haberman Y, Schirmer M, Dexheimer PJ, Karns R, Braun T, Kim MO, Walters TD, Baldassano RN, Noe JD, Rosh J, Markowitz J, Crandall WV, Mack DR, Griffiths AM, Heyman MB, Baker SS, Kellermayer R, Moulton D, Patel AS, Gulati AS, Steiner SJ, LeLeiko N, Otley A, Oliva-Hemker M, Ziring D, Kirschner BS, Keljo DJ, Guthery SL, Cohen SA, Snapper S, Evans J, Dubinsky M, Aronow B, Hyams JS, Kugathasan S, Huttenhower C, Xavier RJ, Denson LA) Mucosal Immunol 2019 Mar;12(2):491-502       30 Citations
1TRPV4 regulates matrix stiffness and TGFβ1-induced epithelial-mesenchymal transition. (Sharma S, Goswami R, Zhang DX, Rahaman SO) J Cell Mol Med 2019 Feb;23(2):761-774       99 Citations
1Sex-specific airway hyperreactivity and sex-specific transcriptome remodeling in neonatal piglets challenged with intra-airway acid. (Reznikov LR, Liao YSJ, Gu T, Davis KM, Kuan SP, Atanasova KR, Dadural JS, Collins EN, Guevara MV, Vogt K) Am J Physiol Lung Cell Mol Physiol 2019 Jan 01;316(1):L131-L143       9 Citations
1Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides. (Wang Y, Mukhopadhyay R, Roy S, Kapoor A, Su YP, Charman SA, Chen G, Wu J, Wang X, Vennerstrom JL, Arav-Boger R) Antimicrob Agents Chemother 2019 Jan;63(1)       14 Citations
2Current status and strategies of long noncoding RNA research for diabetic cardiomyopathy. (Pant T, Dhanasekaran A, Fang J, Bai X, Bosnjak ZJ, Liang M, Ge ZD) BMC Cardiovasc Disord 2018 Oct 20;18(1):197       43 Citations
3Yap is required for scar formation but not myocyte proliferation during heart regeneration in zebrafish. (Flinn MA, Jeffery BE, O'Meara CC, Link BA) Cardiovasc Res 2019 Mar 01;115(3):570-577       35 Citations
1Gene expression of TWIST1 and ZBTB16 is regulated by methylation modifications during the osteoblastic differentiation of mesenchymal stem cells. (Marofi F, Vahedi G, Solali S, Alivand M, Salarinasab S, Zadi Heydarabad M, Farshdousti Hagh M) J Cell Physiol 2019 May;234(5):6230-6243       42 Citations
1GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism. (Tanimura N, Liao R, Wilson GM, Dent MR, Cao M, Burstyn JN, Hematti P, Liu X, Zhang Y, Zheng Y, Keles S, Xu J, Coon JJ, Bresnick EH) Dev Cell 2018 Sep 10;46(5):581-594.e4       38 Citations
1Intraperitoneal injection of MSC-derived exosomes prevent experimental bronchopulmonary dysplasia. (Braun RK, Chetty C, Balasubramaniam V, Centanni R, Haraldsdottir K, Hematti P, Eldridge MW) Biochem Biophys Res Commun 2018 Sep 18;503(4):2653-2658       119 Citations
1Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency. (Rak MA, Buehler J, Zeltzer S, Reitsma J, Molina B, Terhune S, Goodrum F) J Virol 2018 Oct 15;92(20)       40 Citations
1Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina. (Miesfeld JB, Moon MS, Riesenberg AN, Contreras AN, Kovall RA, Brown NL) Sci Rep 2018 Jul 05;8(1):10195       17 Citations
2Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer's disease. (López A, Aparicio N, Pazos MR, Grande MT, Barreda-Manso MA, Benito-Cuesta I, Vázquez C, Amores M, Ruiz-Pérez G, García-García E, Beatka M, Tolón RM, Dittel BN, Hillard CJ, Romero J) J Neuroinflammation 2018 May 24;15(1):158       127 Citations
2GPR40 is a low-affinity epoxyeicosatrienoic acid receptor in vascular cells. (Park SK, Herrnreiter A, Pfister SL, Gauthier KM, Falck BA, Falck JR, Campbell WB) J Biol Chem 2018 Jul 06;293(27):10675-10691       65 Citations
1Functions of TGIF homeodomain proteins and their roles in normal brain development and holoprosencephaly. (Wotton D, Taniguchi K) Am J Med Genet C Semin Med Genet 2018 Jun;178(2):128-139       16 Citations
1Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging. (De Silva TM, Li Y, Kinzenbaw DA, Sigmund CD, Faraci FM) Hypertension 2018 Jul;72(1):227-234       40 Citations
1Effect of a melanocortin type 2 receptor (MC2R) antagonist on the corticosterone response to hypoxia and ACTH stimulation in the neonatal rat. (Goldenberg AJ, Gehrand AL, Waples E, Jablonski M, Hoeynck B, Raff H) Am J Physiol Regul Integr Comp Physiol 2018 Jul 01;315(1):R128-R133       10 Citations
3Transcriptomic analysis reveals inflammatory and metabolic pathways that are regulated by renal perfusion pressure in the outer medulla of Dahl-S rats. (Evans LC, Dayton A, Yang C, Liu P, Kurth T, Ahn KW, Komas S, Stingo FC, Laud PW, Vannucci M, Liang M, Cowley AW Jr) Physiol Genomics 2018 Jun 01;50(6):440-447       13 Citations
1Regulation of apoptosis by an intrinsically disordered region of Bcl-xL. (Follis AV, Llambi F, Kalkavan H, Yao Y, Phillips AH, Park CG, Marassi FM, Green DR, Kriwacki RW) Nat Chem Biol 2018 May;14(5):458-465       45 Citations
1Stat3 and CCAAT enhancer-binding protein β (C/ebpβ) activate Fanconi C gene transcription during emergency granulopoiesis. (Shah CA, Broglie L, Hu L, Bei L, Huang W, Dressler DB, Eklund EA) J Biol Chem 2018 Mar 16;293(11):3937-3948       8 Citations
3miR-29 contributes to normal endothelial function and can restore it in cardiometabolic disorders. (Widlansky ME, Jensen DM, Wang J, Liu Y, Geurts AM, Kriegel AJ, Liu P, Ying R, Zhang G, Casati M, Chu C, Malik M, Branum A, Tanner MJ, Tyagi S, Usa K, Liang M) EMBO Mol Med 2018 Mar;10(3)       86 Citations
1Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. (Zhao MT, Chen H, Liu Q, Shao NY, Sayed N, Wo HT, Zhang JZ, Ong SG, Liu C, Kim Y, Yang H, Chour T, Ma H, Gutierrez NM, Karakikes I, Mitalipov S, Snyder MP, Wu JC) Proc Natl Acad Sci U S A 2017 Dec 26;114(52):E11111-E11120       69 Citations
1STAT5a and STAT6 gene expression levels in multiple sclerosis patients. (Hatami M, Salmani T, Arsang-Jang S, Davood Omrani M, Mazdeh M, Ghafouri-Fard S, Sayad A, Taheri M) Cytokine 2018 Jun;106:108-113       24 Citations
1High Content Screening of Mammalian Primary Cortical Neurons. (Motti D, Blackmore M, Bixby JL, Lemmon VP) Methods Mol Biol 2018;1683:293-304       1 Citation
1Enhanced hepatogenic differentiation of bone marrow derived mesenchymal stem cells on liver ECM hydrogel. (Wang B, Li W, Dean D, Mishra MK, Wekesa KS) J Biomed Mater Res A 2018 Mar;106(3):829-838       34 Citations
1Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms. (Subramanian VS, Sabui S, Moradi H, Marchant JS, Said HM) Biochim Biophys Acta Biomembr 2018 Feb;1860(2):556-565       51 Citations
1A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses. (Hong SK, Wu PK, Park JI) Cell Signal 2018 Jan;42:11-20       30 Citations
1Gene Expression Profiling and Heterogeneity of Nonspecific Orbital Inflammation Affecting the Lacrimal Gland. (Rosenbaum JT, Choi D, Harrington CA, Wilson DJ, Grossniklaus HE, Sibley CH, Salek SS, Ng JD, Dailey RA, Steele EA, Hayek B, Craven CM, Edward DP, Maktabi AMY, Al Hussain H, White VA, Dolman PJ, Czyz CN, Foster JA, Harris GJ, Bee YS, Tse DT, Alabiad CR, Dubovy SR, Kazim M, Selva D, Yeatts RP, Korn BS, Kikkawa DO, Silkiss RZ, Sivak-Callcott JA, Stauffer P, Planck SR) JAMA Ophthalmol 2017 Nov 01;135(11):1156-1162       37 Citations
1Kindlin supports platelet integrin αIIbβ3 activation by interacting with paxillin. (Gao J, Huang M, Lai J, Mao K, Sun P, Cao Z, Hu Y, Zhang Y, Schulte ML, Jin C, Wang J, White GC, Xu Z, Ma YQ) J Cell Sci 2017 Nov 01;130(21):3764-3775       55 Citations
1Development and characterization of cholangioids from normal and diseased human cholangiocytes as an in vitro model to study primary sclerosing cholangitis. (Loarca L, De Assuncao TM, Jalan-Sakrikar N, Bronk S, Krishnan A, Huang B, Morton L, Trussoni C, Bonilla LM, Krueger E, O'Hara S, Splinter P, Shi G, Pisarello MJL, Gores GJ, Huebert RC, LaRusso NF) Lab Invest 2017 Nov;97(11):1385-1396       42 Citations
1Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease. (Marigorta UM, Denson LA, Hyams JS, Mondal K, Prince J, Walters TD, Griffiths A, Noe JD, Crandall WV, Rosh JR, Mack DR, Kellermayer R, Heyman MB, Baker SS, Stephens MC, Baldassano RN, Markowitz JF, Kim MO, Dubinsky MC, Cho J, Aronow BJ, Kugathasan S, Gibson G) Nat Genet 2017 Oct;49(10):1517-1521       135 Citations
4SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression. (Gonyo P, Bergom C, Brandt AC, Tsaih SW, Sun Y, Bigley TM, Lorimer EL, Terhune SS, Rui H, Flister MJ, Long RM, Williams CL) Oncogene 2017 Dec 14;36(50):6873-6883       13 Citations
1Development of insulin resistance through sprouting of inflammatory markers during hypoxia in 3T3-L1 adipocytes and amelioration with curcumin. (Priyanka A, Shyni GL, Anupama N, Raj PS, Anusree SS, Raghu KG) Eur J Pharmacol 2017 Oct 05;812:73-81       22 Citations
1Integration of DNA methylation and gene transcription across nineteen cell types reveals cell type-specific and genomic region-dependent regulatory patterns. (Tang B, Zhou Y, Wang CM, Huang TH, Jin VX) Sci Rep 2017 Jun 15;7(1):3626       18 Citations
1Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. (Mahmoud MM, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis SE, Van der Heiden K, Ridger V, Evans PC) Sci Rep 2017 Jun 13;7(1):3375       166 Citations
1Endothelin signaling regulates mineralization and posttranscriptionally regulates SOST in TMOb cells via miR 126-3p. (Johnson MG, Konicke K, Kristianto J, Gustavson A, Garbo R, Wang X, Yuan B, Blank RD) Physiol Rep 2017 Feb;5(4)       11 Citations
1Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter. (Singh P, Han EH, Endrizzi JA, O'Brien RM, Chi YI) J Struct Biol 2017 Apr;198(1):54-64       20 Citations
1Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium. (Hoffmann BR, Stodola TJ, Wagner JR, Didier DN, Exner EC, Lombard JH, Greene AS) Arterioscler Thromb Vasc Biol 2017 Mar;37(3):433-445       36 Citations
1Human Lacrimal Gland Gene Expression. (Aakalu VK, Parameswaran S, Maienschein-Cline M, Bahroos N, Shah D, Ali M, Krishnakumar S) PLoS One 2017;12(1):e0169346       15 Citations
1MicroRNA Expression Shows Inflammatory Dysregulation and Tumor-Like Proliferative Responses in Joints of Patients With Postinfectious Lyme Arthritis. (Lochhead RB, Strle K, Kim ND, Kohler MJ, Arvikar SL, Aversa JM, Steere AC) Arthritis Rheumatol 2017 May;69(5):1100-1110       37 Citations
1The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice. (Maiers JL, Kostallari E, Mushref M, deAssuncao TM, Li H, Jalan-Sakrikar N, Huebert RC, Cao S, Malhi H, Shah VH) Hepatology 2017 Mar;65(3):983-998       100 Citations
1Molecular Approaches in HFpEF: MicroRNAs and iPSC-Derived Cardiomyocytes. (Kriegel AJ, Gartz M, Afzal MZ, de Lange WJ, Ralphe JC, Strande JL) J Cardiovasc Transl Res 2017 Jun;10(3):295-304       10 Citations
1TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. (Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS) Aging (Albany NY) 2016 Dec 16;8(12):3507-3519       55 Citations
1Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract. (Subramanian VS, Srinivasan P, Wildman AJ, Marchant JS, Said HM) Am J Physiol Gastrointest Liver Physiol 2017 Apr 01;312(4):G340-G347       28 Citations
1Phosphorylation of Translation Initiation Factor 2-Alpha in Leishmania donovani under Stress Is Necessary for Parasite Survival. (Abhishek K, Sardar AH, Das S, Kumar A, Ghosh AK, Singh R, Saini S, Mandal A, Verma S, Kumar A, Purkait B, Dikhit MR, Das P) Mol Cell Biol 2017 Jan 01;37(1)       20 Citations
1E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts. (Swartz KL, Wood SN, Murthy T, Ramirez O, Qin G, Pillai MM, Rao S, Minella AC) Mol Cell Biol 2017 Jan 01;37(1)       27 Citations
1Interferon Regulatory Factor 1 and Type I Interferon Cooperate To Control Acute Gammaherpesvirus Infection. (Mboko WP, Rekow MM, Ledwith MP, Lange PT, Schmitz KE, Anderson S, Tarakanova VL) J Virol 2017 Jan 01;91(1)       24 Citations
2Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic Hypertension. (Shinohara K, Liu X, Morgan DA, Davis DR, Sequeira-Lopez ML, Cassell MD, Grobe JL, Rahmouni K, Sigmund CD) Hypertension 2016 Dec;68(6):1385-1392       46 Citations
1Differential Molecular Expression of Extracellular Matrix and Inflammatory Genes at the Corneal Cone Apex Drives Focal Weakening in Keratoconus. (Pahuja N, Kumar NR, Shroff R, Shetty R, Nuijts RM, Ghosh A, Sinha-Roy A, Chaurasia SS, Mohan RR, Ghosh A) Invest Ophthalmol Vis Sci 2016 Oct 01;57(13):5372-5382       109 Citations
1Increased expression ratio of matrix metalloproteinase-9 (MMP9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) RNA levels in Iranian multiple sclerosis patients. (Nazdik MK, Taheri M, Sajjadi E, Arsang-Jang S, Koohpar ZK, Inoko H, Sayad A) Hum Antibodies 2016;24(3-4):65-70       17 Citations
1Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes. (Blinka S, Reimer MH Jr, Pulakanti K, Rao S) Cell Rep 2016 Sep 27;17(1):19-28       90 Citations
1Identification of Transcribed Enhancers by Genome-Wide Chromatin Immunoprecipitation Sequencing. (Blinka S, Reimer MH Jr, Pulakanti K, Pinello L, Yuan GC, Rao S) Methods Mol Biol 2017;1468:91-109       17 Citations
1Transcriptional Regulation of Brain-derived Neurotrophic Factor Coding Exon IX: ROLE OF NUCLEAR RESPIRATORY FACTOR 2. (Nair B, Wong-Riley MT) J Biol Chem 2016 Oct 21;291(43):22583-22593       21 Citations
2The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9. (Fisher JB, Peterson J, Reimer M, Stelloh C, Pulakanti K, Gerbec ZJ, Abel AM, Strouse JM, Strouse C, McNulty M, Malarkannan S, Crispino JD, Milanovich S, Rao S) Leukemia 2017 Mar;31(3):712-719       54 Citations
2Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression. (Belle L, Agle K, Zhou V, Yin-Yuan C, Komorowski R, Eastwood D, Logan B, Sun J, Ghilardi N, Cua D, Williams CB, Gaignage M, Marillier R, van Snick J, Drobyski WR) Blood 2016 Oct 20;128(16):2068-2082       38 Citations
2Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy. (Osman EY, Washington CW 3rd, Kaifer KA, Mazzasette C, Patitucci TN, Florea KM, Simon ME, Ko CP, Ebert AD, Lorson CL) Mol Ther 2016 Sep;24(9):1592-601       31 Citations
1A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation. (Himburg HA, Sasine J, Yan X, Kan J, Dressman H, Chute JP) Radiat Res 2016 Aug;186(2):141-52       31 Citations
1Role of PGC-1α in Vascular Regulation: Implications for Atherosclerosis. (Kadlec AO, Chabowski DS, Ait-Aissa K, Gutterman DD) Arterioscler Thromb Vasc Biol 2016 Aug;36(8):1467-74       93 Citations
1Association of expression levels of pluripotency/stem cell markers with the differentiation outcome of Wharton's jelly mesenchymal stem cells into insulin producing cells. (Kassem DH, Kamal MM, El-Kholy Ael-L, El-Mesallamy HO) Biochimie 2016 Aug;127:187-95       14 Citations
1De novo RRAGC mutation activates mTORC1 signaling in syndromic fetal dilated cardiomyopathy. (Long PA, Zimmermann MT, Kim M, Evans JM, Xu X, Olson TM) Hum Genet 2016 Aug;135(8):909-917       31 Citations
1Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke. (Yu G, Liang Y, Huang Z, Jones DW, Pritchard KA Jr, Zhang H) J Neuroinflammation 2016 May 24;13(1):119       59 Citations
1Thrombospondin-4 divergently regulates voltage-gated Ca2+ channel subtypes in sensory neurons after nerve injury. (Pan B, Guo Y, Wu HE, Park J, Trinh VN, Luo ZD, Hogan QH) Pain 2016 Sep;157(9):2068-2080       33 Citations
2Raphe gene expression changes implicate immune-related functions in ventilatory plasticity following carotid body denervation in rats. (Mouradian GC Jr, Liu P, Hodges MR) Exp Neurol 2017 Jan;287(Pt 2):102-112       5 Citations
1Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression. (Lu KT, Keen HL, Weatherford ET, Sequeira-Lopez ML, Gomez RA, Sigmund CD) Hypertension 2016 May;67(5):992-9       20 Citations
1ITF2357 transactivates Id3 and regulate TGFβ/BMP7 signaling pathways to attenuate corneal fibrosis. (Lim RR, Tan A, Liu YC, Barathi VA, Mohan RR, Mehta JS, Chaurasia SS) Sci Rep 2016 Feb 11;6:20841       49 Citations
1Inhibitors for the Vitamin D Receptor-Coregulator Interaction. (Teske KA, Yu O, Arnold LA) Vitam Horm 2016;100:45-82       10 Citations
1Host gene expression classifiers diagnose acute respiratory illness etiology. (Tsalik EL, Henao R, Nichols M, Burke T, Ko ER, McClain MT, Hudson LL, Mazur A, Freeman DH, Veldman T, Langley RJ, Quackenbush EB, Glickman SW, Cairns CB, Jaehne AK, Rivers EP, Otero RM, Zaas AK, Kingsmore SF, Lucas J, Fowler VG Jr, Carin L, Ginsburg GS, Woods CW) Sci Transl Med 2016 Jan 20;8(322):322ra11       214 Citations
1Fibrotic Aortic Valve Stenosis in Hypercholesterolemic/Hypertensive Mice. (Chu Y, Lund DD, Doshi H, Keen HL, Knudtson KL, Funk ND, Shao JQ, Cheng J, Hajj GP, Zimmerman KA, Davis MK, Brooks RM, Chapleau MW, Sigmund CD, Weiss RM, Heistad DD) Arterioscler Thromb Vasc Biol 2016 Mar;36(3):466-74       20 Citations
1Probable Chemical Hypoxia Effects on Progress of CNV Through Induction of Promoter CpG Demethylation and Overexpression of IL17RC in Human RPE Cells. (Alivand MR, Sabouni F, Soheili ZS) Curr Eye Res 2016 Sep;41(9):1245-54       19 Citations
1Characterization of Inhibitor of differentiation (Id) proteins in human cornea. (Mohan RR, Morgan BR, Anumanthan G, Sharma A, Chaurasia SS, Rieger FG) Exp Eye Res 2016 May;146:145-153       16 Citations
3Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. (Cowley AW Jr, Yang C, Zheleznova NN, Staruschenko A, Kurth T, Rein L, Kumar V, Sadovnikov K, Dayton A, Hoffman M, Ryan RP, Skelton MM, Salehpour F, Ranji M, Geurts A) Hypertension 2016 Feb;67(2):440-50       97 Citations
2SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons. (Patitucci TN, Ebert AD) Hum Mol Genet 2016 Feb 01;25(3):514-23       36 Citations
3The introduction of RNA-DNA differences underlies interindividual variation in the human IL12RB1 mRNA repertoire. (Turner AJ, Aggarwal P, Miller HE, Waukau J, Routes JM, Broeckel U, Robinson RT) Proc Natl Acad Sci U S A 2015 Dec 15;112(50):15414-9       6 Citations
1Potential of Horse Apple Isoflavones in Targeting Inflammation and Tau Protein Fibrillization. (Abourashed EA, Abraha A, Khan SI, McCants T, Awan S) Nat Prod Commun 2015 Sep;10(9):1577-80       7 Citations
2Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator-Activated Receptor-γ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate-Salt Hypertension. (Ketsawatsomkron P, Keen HL, Davis DR, Lu KT, Stump M, De Silva TM, Hilzendeger AM, Grobe JL, Faraci FM, Sigmund CD) Hypertension 2016 Jan;67(1):214-22       23 Citations
1Endothelial PPAR-γ provides vascular protection from IL-1β-induced oxidative stress. (Mukohda M, Stump M, Ketsawatsomkron P, Hu C, Quelle FW, Sigmund CD) Am J Physiol Heart Circ Physiol 2016 Jan 01;310(1):H39-48       55 Citations
2Pappa2 is linked to salt-sensitive hypertension in Dahl S rats. (Cowley AW Jr, Yang C, Kumar V, Lazar J, Jacob H, Geurts AM, Liu P, Dayton A, Kurth T, Liang M) Physiol Genomics 2016 Jan;48(1):62-72       34 Citations
2Von Willebrand factor is reversibly decreased during torpor in 13-lined ground squirrels. (Cooper S, Sell S, Nelson L, Hawes J, Benrud JA, Kohlnhofer BM, Burmeister BR, Flood VH) J Comp Physiol B 2016 Jan;186(1):131-9       16 Citations
1Specificity protein 4 (Sp4) transcriptionally regulates inhibitory GABAergic receptors in neurons. (Nair B, Johar K, Priya A, Wong-Riley MT) Biochim Biophys Acta 2016 Jan;1863(1):1-9       18 Citations
1CCR5-Dependent Activation of mTORC1 Regulates Translation of Inducible NO Synthase and COX-2 during Encephalomyocarditis Virus Infection. (Shaheen ZR, Naatz A, Corbett JA) J Immunol 2015 Nov 01;195(9):4406-14       14 Citations
2Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. (Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE) J Clin Invest 2015 Oct 01;125(10):3819-30       70 Citations
1Macrophage Expression of Inflammatory Genes in Response to EMCV Infection. (Shaheen ZR, Corbett JA) Biomolecules 2015 Aug 18;5(3):1938-54       11 Citations
1Lipin-1 contributes to modified low-density lipoprotein-elicited macrophage pro-inflammatory responses. (Navratil AR, Vozenilek AE, Cardelli JA, Green JM, Thomas MJ, Sorci-Thomas MG, Orr AW, Woolard MD) Atherosclerosis 2015 Oct;242(2):424-32       18 Citations
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1Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration. (Mahmoud AI, O'Meara CC, Gemberling M, Zhao L, Bryant DM, Zheng R, Gannon JB, Cai L, Choi WY, Egnaczyk GF, Burns CE, Burns CG, MacRae CA, Poss KD, Lee RT) Dev Cell 2015 Aug 24;34(4):387-99       227 Citations
1Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis. (Lochhead RB, Zachary JF, Dalla Rosa L, Ma Y, Weis JH, O'Connell RM, Weis JJ) PLoS One 2015;10(8):e0135142       27 Citations
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1Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis. (Jiang J, Burgon PG, Wakimoto H, Onoue K, Gorham JM, O'Meara CC, Fomovsky G, McConnell BK, Lee RT, Seidman JG, Seidman CE) Proc Natl Acad Sci U S A 2015 Jul 21;112(29):9046-51       44 Citations
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1B-Type Natriuretic Peptide Deletion Leads to Progressive Hypertension, Associated Organ Damage, and Reduced Survival: Novel Model for Human Hypertension. (Holditch SJ, Schreiber CA, Nini R, Tonne JM, Peng KW, Geurts A, Jacob HJ, Burnett JC, Cataliotti A, Ikeda Y) Hypertension 2015 Jul;66(1):199-210       58 Citations
1Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation. (Handley MT, Carpanini SM, Mali GR, Sidjanin DJ, Aligianis IA, Jackson IJ, FitzPatrick DR) Open Biol 2015 Jun;5(6):150047       46 Citations
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3The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage. (Leonard PH, Grzenda A, Mathison A, Morbeck DE, Fredrickson JR, de Assuncao TM, Christensen T, Salisbury J, Calvo E, Iovanna J, Coddington CC, Urrutia R, Lomberk G) BMC Dev Biol 2015 May 29;15:23       7 Citations
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22015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research. (Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A, International Committee on Standardized Genetic Nomenclature for Mice, Rat Genome and Nomenclature Committee) J Cardiovasc Transl Res 2015 Jun;8(4):269-77       23 Citations
1Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo. (Hasan DM, Starke RM, Gu H, Wilson K, Chu Y, Chalouhi N, Heistad DD, Faraci FM, Sigmund CD) Hypertension 2015 Jul;66(1):211-20       34 Citations
2Astrocytes influence the severity of spinal muscular atrophy. (Rindt H, Feng Z, Mazzasette C, Glascock JJ, Valdivia D, Pyles N, Crawford TO, Swoboda KJ, Patitucci TN, Ebert AD, Sumner CJ, Ko CP, Lorson CL) Hum Mol Genet 2015 Jul 15;24(14):4094-102       113 Citations
1Tissue-specific targeting of cell fate regulatory genes by E2f factors. (Julian LM, Liu Y, Pakenham CA, Dugal-Tessier D, Ruzhynsky V, Bae S, Tsai SY, Leone G, Slack RS, Blais A) Cell Death Differ 2016 Apr;23(4):565-75       27 Citations
1Parallel Gene Expression Changes in Sarcoidosis Involving the Lacrimal Gland, Orbital Tissue, or Blood. (Rosenbaum JT, Choi D, Wilson DJ, Grossniklaus HE, Harrington CA, Sibley CH, Dailey RA, Ng JD, Steele EA, Czyz CN, Foster JA, Tse D, Alabiad C, Dubovy S, Parekh P, Harris GJ, Kazim M, Patel P, White V, Dolman P, Korn BS, Kikkawa D, Edward DP, Alkatan H, Al-Hussain H, Yeatts RP, Selva D, Stauffer P, Planck SR) JAMA Ophthalmol 2015 Jul;133(7):770-7       36 Citations
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1The tumor virus landscape of AIDS-related lymphomas. (Arvey A, Ojesina AI, Pedamallu CS, Ballon G, Jung J, Duke F, Leoncini L, De Falco G, Bressman E, Tam W, Chadburn A, Meyerson M, Cesarman E) Blood 2015 May 14;125(20):e14-22       70 Citations
1EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice. (Liang HP, Kerschen EJ, Hernandez I, Basu S, Zogg M, Botros F, Jia S, Hessner MJ, Griffin JH, Ruf W, Weiler H) Blood 2015 Apr 30;125(18):2845-54       75 Citations
1Redox signaling and splicing dependent change in myosin phosphatase underlie early versus late changes in NO vasodilator reserve in a mouse LPS model of sepsis. (Reho JJ, Zheng X, Asico LD, Fisher SA) Am J Physiol Heart Circ Physiol 2015 May 01;308(9):H1039-50       23 Citations
1Alcohol inhibits osteopontin-dependent transforming growth factor-β1 expression in human mesenchymal stem cells. (Driver J, Weber CE, Callaci JJ, Kothari AN, Zapf MA, Roper PM, Borys D, Franzen CA, Gupta GN, Wai PY, Zhang J, Denning MF, Kuo PC, Mi Z) J Biol Chem 2015 Apr 17;290(16):9959-73       29 Citations
1Overexpression of Sox11 promotes corticospinal tract regeneration after spinal injury while interfering with functional recovery. (Wang Z, Reynolds A, Kirry A, Nienhaus C, Blackmore MG) J Neurosci 2015 Feb 18;35(7):3139-45       135 Citations
2A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells. (Tsaih SW, Presa M, Khaja S, Ciecko AE, Serreze DV, Chen YG) Genes Immun 2015;16(3):221-30       7 Citations
1Elevated expression of matrix metalloproteinase-9 and inflammatory cytokines in keratoconus patients is inhibited by cyclosporine A. (Shetty R, Ghosh A, Lim RR, Subramani M, Mihir K, Reshma AR, Ranganath A, Nagaraj S, Nuijts RM, Beuerman R, Shetty R, Das D, Chaurasia SS, Sinha-Roy A, Ghosh A) Invest Ophthalmol Vis Sci 2015 Feb 03;56(2):738-50       200 Citations
1Deficiency in the Formation of 20-Hydroxyeicosatetraenoic Acid Enhances Renal Ischemia-Reperfusion Injury. (Muroya Y, Fan F, Regner KR, Falck JR, Garrett MR, Juncos LA, Roman RJ) J Am Soc Nephrol 2015 Oct;26(10):2460-9       25 Citations
1Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL. (Tavori H, Su YR, Yancey PG, Giunzioni I, Wilhelm AJ, Blakemore JL, Zabalawi M, Linton MF, Sorci-Thomas MG, Fazio S) J Lipid Res 2015 Mar;56(3):635-643       27 Citations
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1Developing a clinically feasible personalized medicine approach to pediatric septic shock. (Wong HR, Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Shanley TP, Quasney M, Hall M, Gedeit R, Freishtat RJ, Nowak J, Shekhar RS, Gertz S, Dawson E, Howard K, Harmon K, Beckman E, Frank E, Lindsell CJ) Am J Respir Crit Care Med 2015 Feb 01;191(3):309-15       258 Citations
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1T-bet is critical for the development of acute graft-versus-host disease through controlling T cell differentiation and function. (Fu J, Wang D, Yu Y, Heinrichs J, Wu Y, Schutt S, Kaosaard K, Liu C, Haarberg K, Bastian D, McDonald DG, Anasetti C, Yu XZ) J Immunol 2015 Jan 01;194(1):388-97       36 Citations
2Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats. (Fan F, Geurts AM, Pabbidi MR, Smith SV, Harder DR, Jacob H, Roman RJ) PLoS One 2014;9(11):e112878       33 Citations
1Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production. (Ma Y, Bramwell KK, Lochhead RB, Paquette JK, Zachary JF, Weis JH, Teuscher C, Weis JJ) J Immunol 2014 Dec 15;193(12):6050-60       23 Citations
2Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. (Bohnsack RN, Warejcka DJ, Wang L, Gillespie SR, Bernstein AM, Twining SS, Dahms NM) Invest Ophthalmol Vis Sci 2014 Oct 30;55(12):7697-708       21 Citations
3Sickle cell disease increases high mobility group box 1: a novel mechanism of inflammation. (Xu H, Wandersee NJ, Guo Y, Jones DW, Holzhauer SL, Hanson MS, Machogu E, Brousseau DC, Hogg N, Densmore JC, Kaul S, Hillery CA, Pritchard KA Jr) Blood 2014 Dec 18;124(26):3978-81       48 Citations
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1Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells. (Han L, Li Y, Tchao J, Kaplan AD, Lin B, Li Y, Mich-Basso J, Lis A, Hassan N, London B, Bett GC, Tobita K, Rasmusson RL, Yang L) Cardiovasc Res 2014 Nov 01;104(2):258-69       167 Citations
1Involvement of GABA transporters in atropine-treated myopic retina as revealed by iTRAQ quantitative proteomics. (Barathi VA, Chaurasia SS, Poidinger M, Koh SK, Tian D, Ho C, Iuvone PM, Beuerman RW, Zhou L) J Proteome Res 2014 Nov 07;13(11):4647-58       82 Citations
1Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect. (Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B) Nat Commun 2014 Sep 04;5:4746       88 Citations
1miR-21 in ischemia/reperfusion injury: a double-edged sword? (Xu X, Kriegel AJ, Jiao X, Liu H, Bai X, Olson J, Liang M, Ding X) Physiol Genomics 2014 Nov 01;46(21):789-97       102 Citations
1TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. (Kroner A, Greenhalgh AD, Zarruk JG, Passos Dos Santos R, Gaestel M, David S) Neuron 2014 Sep 03;83(5):1098-116       586 Citations
1HIV-derived ssRNA binds to TLR8 to induce inflammation-driven macrophage foam cell formation. (Bernard MA, Han X, Inderbitzin S, Agbim I, Zhao H, Koziel H, Tachado SD) PLoS One 2014;9(8):e104039       27 Citations
1Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. (Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH) Hum Mol Genet 2014 Dec 15;23(24):6528-41       103 Citations
1MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi. (Lochhead RB, Ma Y, Zachary JF, Baltimore D, Zhao JL, Weis JH, O'Connell RM, Weis JJ) PLoS Pathog 2014 Jun;10(6):e1004212       38 Citations
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2Single and combinatorial chromatin coupling events underlies the function of transcript factor Krüppel-like factor 11 in the regulation of gene networks. (Calvo E, Grzenda A, Lomberk G, Mathison A, Iovanna J, Urrutia R) BMC Mol Biol 2014 May 25;15:10       6 Citations
1Stress regulates endocannabinoid-CB1 receptor signaling. (Hillard CJ) Semin Immunol 2014 Oct;26(5):380-8       113 Citations
1Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed. (Tint GS, Pan L, Shang Q, Sharpe LJ, Brown AJ, Li M, Yu H) Dev Neurosci 2014;36(2):132-42       4 Citations
1FGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway. (Yaqoob U, Jagavelu K, Shergill U, de Assuncao T, Cao S, Shah VH) PLoS One 2014;9(5):e98130       27 Citations
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1Platelet-derived S100 family member myeloid-related protein-14 regulates thrombosis. (Wang Y, Fang C, Gao H, Bilodeau ML, Zhang Z, Croce K, Liu S, Morooka T, Sakuma M, Nakajima K, Yoneda S, Shi C, Zidar D, Andre P, Stephens G, Silverstein RL, Hogg N, Schmaier AH, Simon DI) J Clin Invest 2014 May;124(5):2160-71       133 Citations
1Assessment of microRNA-related SNP effects in the 3' untranslated region of the IL22RA2 risk locus in multiple sclerosis. (Lill CM, Schilling M, Ansaloni S, Schröder J, Jaedicke M, Luessi F, Schjeide BM, Mashychev A, Graetz C, Akkad DA, Gerdes LA, Kroner A, Blaschke P, Hoffjan S, Winkelmann A, Dörner T, Rieckmann P, Steinhagen-Thiessen E, Lindenberger U, Chan A, Hartung HP, Aktas O, Lohse P, Buttmann M, Kümpfel T, Kubisch C, Zettl UK, Epplen JT, Zipp F, Bertram L) Neurogenetics 2014 May;15(2):129-34       15 Citations
1A conserved BDNF, glutamate- and GABA-enriched gene module related to human depression identified by coexpression meta-analysis and DNA variant genome-wide association studies. (Chang LC, Jamain S, Lin CW, Rujescu D, Tseng GC, Sibille E) PLoS One 2014;9(3):e90980       90 Citations
1Characterization of Toll-like receptors 1-10 in spotted hyenas. (Flies AS, Maksimoski MT, Mansfield LS, Weldele ML, Holekamp KE) Vet Res Commun 2014 Jun;38(2):165-70       8 Citations
1Depletion of the protein kinase VRK1 disrupts nuclear envelope morphology and leads to BAF retention on mitotic chromosomes. (Molitor TP, Traktman P) Mol Biol Cell 2014 Mar;25(6):891-903       84 Citations
1Heat shock modulates neutrophil motility in zebrafish. (Lam PY, Harvie EA, Huttenlocher A) PLoS One 2013;8(12):e84436       30 Citations
1CD247 modulates blood pressure by altering T-lymphocyte infiltration in the kidney. (Rudemiller N, Lund H, Jacob HJ, Geurts AM, Mattson DL, PhysGen Knockout Program) Hypertension 2014 Mar;63(3):559-64       135 Citations
1Curcumin and anthocyanin inhibit pepsin-mediated cell damage and carcinogenic changes in airway epithelial cells. (Samuels TL, Pearson AC, Wells CW, Stoner GD, Johnston N) Ann Otol Rhinol Laryngol 2013 Oct;122(10):632-41       28 Citations
2Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells. (Shi Q, Kuether EL, Chen Y, Schroeder JA, Fahs SA, Montgomery RR) Blood 2014 Jan 16;123(3):395-403       45 Citations
4Platelet-targeted gene therapy with human factor VIII establishes haemostasis in dogs with haemophilia A. (Du LM, Nurden P, Nurden AT, Nichols TC, Bellinger DA, Jensen ES, Haberichter SL, Merricks E, Raymer RA, Fang J, Koukouritaki SB, Jacobi PM, Hawkins TB, Cornetta K, Shi Q, Wilcox DA) Nat Commun 2013;4:2773       104 Citations
1SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1. (Zhou X, Fan LX, Li K, Ramchandran R, Calvet JP, Li X) Hum Mol Genet 2014 Mar 15;23(6):1644-55       47 Citations
1Sustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomes. (King AJ, Guo Y, Cai D, Hollister-Lock J, Morris B, Salvatori A, Corbett JA, Bonner-Weir S, Shoelson SE, Weir GC) PLoS One 2013;8(10):e77452       11 Citations
2Chemokines in colitis: microRNA control. (Roy I, Veldkamp CT, Volkman BF, Dwinell MB) Gut 2014 Aug;63(8):1202-4       5 Citations
1L-Threonine induces heat shock protein expression and decreases apoptosis in heat-stressed intestinal epithelial cells. (Baird CH, Niederlechner S, Beck R, Kallweit AR, Wischmeyer PE) Nutrition 2013;29(11-12):1404-11       33 Citations
1Endothelial metabolism of angiotensin II to angiotensin III, not angiotensin (1-7), augments the vasorelaxation response in adrenal cortical arteries. (Kopf PG, Campbell WB) Endocrinology 2013 Dec;154(12):4768-76       11 Citations
1Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs. (Kriegel AJ, Liu Y, Liu P, Baker MA, Hodges MR, Hua X, Liang M) Physiol Genomics 2013 Dec 01;45(23):1144-56       30 Citations
1Small RNA profiling of influenza A virus-infected cells identifies miR-449b as a regulator of histone deacetylase 1 and interferon beta. (Buggele WA, Krause KE, Horvath CM) PLoS One 2013;8(9):e76560       39 Citations
2Role for Krüppel-like transcription factor 11 in mesenchymal cell function and fibrosis. (Mathison A, Grzenda A, Lomberk G, Velez G, Buttar N, Tietz P, Hendrickson H, Liebl A, Xiong YY, Gores G, Fernandez-Zapico M, Larusso NF, Faubion W, Shah VH, Urrutia R) PLoS One 2013;8(9):e75311       26 Citations
1Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells. (Hwang CK, Chaurasia SS, Jackson CR, Chan GC, Storm DR, Iuvone PM) J Neurosci 2013 Sep 18;33(38):14989-97       66 Citations
1Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells. (Rajasekaran K, Kumar P, Schuldt KM, Peterson EJ, Vanhaesebroeck B, Dixit V, Thakar MS, Malarkannan S) Nat Immunol 2013 Nov;14(11):1127-36       80 Citations
1A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation. (Boccuto L, Aoki K, Flanagan-Steet H, Chen CF, Fan X, Bartel F, Petukh M, Pittman A, Saul R, Chaubey A, Alexov E, Tiemeyer M, Steet R, Schwartz CE) Hum Mol Genet 2014 Jan 15;23(2):418-33       159 Citations
1Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects. (Subramanian VS, Nabokina SM, Lin-Moshier Y, Marchant JS, Said HM) PLoS One 2013;8(8):e73503       29 Citations
1Enhanced dopamine release by mesenchymal stem cells reprogrammed neuronally by the modulators of SMAD signaling, chromatin modifying enzymes, and cyclic adenosine monophosphate levels. (Funk RT, Alexanian AR) Transl Res 2013 Nov;162(5):317-23       6 Citations
1Mechanical vibration inhibits osteoclast formation by reducing DC-STAMP receptor expression in osteoclast precursor cells. (Kulkarni RN, Voglewede PA, Liu D) Bone 2013 Dec;57(2):493-8       36 Citations
1A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. (Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA) Hum Mol Genet 2014 Jan 01;23(1):194-208       23 Citations
1Mice with a targeted disruption of Slc4a11 model the progressive corneal changes of congenital hereditary endothelial dystrophy. (Han SB, Ang HP, Poh R, Chaurasia SS, Peh G, Liu J, Tan DT, Vithana EN, Mehta JS) Invest Ophthalmol Vis Sci 2013 Sep 27;54(9):6179-89       55 Citations
1Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction. (Chrzanowska-Wodnicka M) Exp Cell Res 2013 Sep 10;319(15):2350-9       51 Citations
1Comparative analysis of adipose-derived mesenchymal stem cells isolated from abdominal and breast tissue. (Hanson SE, Kim J, Hematti P) Aesthet Surg J 2013 Aug 01;33(6):888-98       32 Citations
2Canonical Wnt signaling is necessary for object recognition memory consolidation. (Fortress AM, Schram SL, Tuscher JJ, Frick KM) J Neurosci 2013 Jul 31;33(31):12619-26       100 Citations
1GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2. (Coma S, Allard-Ratick M, Akino T, van Meeteren LA, Mammoto A, Klagsbrun M) Angiogenesis 2013 Oct;16(4):939-52       51 Citations
1Gene expression and pathologic alterations in juvenile rainbow trout due to chronic dietary TCDD exposure. (Liu Q, Rise ML, Spitsbergen JM, Hori TS, Mieritz M, Geis S, McGraw JE, Goetz G, Larson J, Hutz RJ, Carvan MJ 3rd) Aquat Toxicol 2013 Sep 15;140-141:356-68       20 Citations
1Effects of interleukin-6 on the expression of tight junction proteins in isolated cerebral microvessels from yearling and adult sheep. (Cohen SS, Min M, Cummings EE, Chen X, Sadowska GB, Sharma S, Stonestreet BS) Neuroimmunomodulation 2013;20(5):264-73       67 Citations
1Regulation of angiogenesis by phospholipid lysophosphatidic acid. (Chen Y, Ramakrishnan DP, Ren B) Front Biosci (Landmark Ed) 2013 Jun 01;18(3):852-61       26 Citations
1Blood pressure, artery size, and artery compliance parallel bone size and strength in mice with differing ece1 expression. (Wang Z, Kristianto J, Yen Ooi C, Johnson MG, Litscher SJ, Pugh TD, Sandhu G, Chesler NC, Blank RD) J Biomech Eng 2013 Jun;135(6):61003-9       5 Citations
2Allele-specific expression of angiotensinogen in human subcutaneous adipose tissue. (Park S, Lu KT, Liu X, Chatterjee TK, Rudich SM, Weintraub NL, Kwitek AE, Sigmund CD) Hypertension 2013 Jul;62(1):41-7       13 Citations
2Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young. (Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R) J Biol Chem 2013 Jun 14;288(24):17745-58       30 Citations
1In vitro characterization of macrophage interaction with mesenchymal stromal cell-hyaluronan hydrogel constructs. (King SN, Hanson SE, Chen X, Kim J, Hematti P, Thibeault SL) J Biomed Mater Res A 2014 Mar;102(3):890-902       38 Citations
1Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. (Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS) Cell Stem Cell 2013 Apr 04;12(4):440-52       74 Citations
1Deleterious cholesterol hydroperoxide trafficking in steroidogenic acute regulatory (StAR) protein-expressing MA-10 Leydig cells: implications for oxidative stress-impaired steroidogenesis. (Korytowski W, Pilat A, Schmitt JC, Girotti AW) J Biol Chem 2013 Apr 19;288(16):11509-19       34 Citations
1Modeling human protein aggregation cardiomyopathy using murine induced pluripotent stem cells. (Limphong P, Zhang H, Christians E, Liu Q, Riedel M, Ivey K, Cheng P, Mitzelfelt K, Taylor G, Winge D, Srivastava D, Benjamin I) Stem Cells Transl Med 2013 Mar;2(3):161-6       8 Citations
1Genome-wide analysis uncovers high frequency, strong differential chromosomal interactions and their associated epigenetic patterns in E2-mediated gene regulation. (Wang J, Lan X, Hsu PY, Hsu HK, Huang K, Parvin J, Huang TH, Jin VX) BMC Genomics 2013 Jan 31;14:70       39 Citations
1Pioglitazone attenuates valvular calcification induced by hypercholesterolemia. (Chu Y, Lund DD, Weiss RM, Brooks RM, Doshi H, Hajj GP, Sigmund CD, Heistad DD) Arterioscler Thromb Vasc Biol 2013 Mar;33(3):523-32       50 Citations
1Fluid flow shear stress upregulates prostanoid receptor EP2 but not EP4 in murine podocytes. (Srivastava T, McCarthy ET, Sharma R, Kats A, Carlton CG, Alon US, Cudmore PA, El-Meanawy A, Sharma M) Prostaglandins Other Lipid Mediat 2013;104-105:49-57       23 Citations
1Heterozygous knockout of transforming growth factor-β1 protects Dahl S rats against high salt-induced renal injury. (Chen CC, Geurts AM, Jacob HJ, Fan F, Roman RJ) Physiol Genomics 2013 Feb 04;45(3):110-8       21 Citations
1Human cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection. (Savaryn JP, Reitsma JM, Bigley TM, Halligan BD, Qian Z, Yu D, Terhune SS) J Virol 2013 Mar;87(5):2463-74       28 Citations
2Transient repetitive exposure to low level light therapy enhances collateral blood vessel growth in the ischemic hindlimb of the tight skin mouse. (Zaidi M, Krolikowki JG, Jones DW, Pritchard KA Jr, Struve J, Nandedkar SD, Lohr NL, Pagel PS, Weihrauch D) Photochem Photobiol 2013;89(3):709-13       19 Citations
1Transcriptional pathways and potential therapeutic targets in the regulation of Ncx1 expression in cardiac hypertrophy and failure. (Menick DR, Li MS, Chernysh O, Renaud L, Kimbrough D, Kasiganesan H, Mani SK) Adv Exp Med Biol 2013;961:125-35       18 Citations
1Increased dietary intake of vitamin A promotes aortic valve calcification in vivo. (Huk DJ, Hammond HL, Kegechika H, Lincoln J) Arterioscler Thromb Vasc Biol 2013 Feb;33(2):285-93       31 Citations
1A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse. (Kerschner JE, Hong W, Taylor SR, Kerschner JA, Khampang P, Wrege KC, North PE) Int J Pediatr Otorhinolaryngol 2013 Jan;77(1):79-84       25 Citations
4Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat. (Yang C, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Skelton M, O'Connor P, Kurth T, Ryan RP, Moreno C, Tsaih SW, Patone G, Hummel O, Jacob HJ, Liang M, Cowley AW Jr) Hypertension 2013 Jan;61(1):208-15       18 Citations
1Re-evaluation of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling. (Lin-Moshier Y, Sebastian PJ, Higgins L, Sampson ND, Hewitt JE, Marchant JS) J Biol Chem 2013 Jan 04;288(1):355-67       77 Citations
1iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration. (Singh R, Shen W, Kuai D, Martin JM, Guo X, Smith MA, Perez ET, Phillips MJ, Simonett JM, Wallace KA, Verhoeven AD, Capowski EE, Zhang X, Yin Y, Halbach PJ, Fishman GA, Wright LS, Pattnaik BR, Gamm DM) Hum Mol Genet 2013 Feb 01;22(3):593-607       198 Citations
1TRPA1 is functionally expressed primarily by IB4-binding, non-peptidergic mouse and rat sensory neurons. (Barabas ME, Kossyreva EA, Stucky CL) PLoS One 2012;7(10):e47988       93 Citations
1Nuclear respiratory factor 2 regulates the expression of the same NMDA receptor subunit genes as NRF-1: both factors act by a concurrent and parallel mechanism to couple energy metabolism and synaptic transmission. (Priya A, Johar K, Wong-Riley MT) Biochim Biophys Acta 2013 Jan;1833(1):48-58       20 Citations
1Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells. (Yu M, Chen Y, He Y, Podd A, Fu G, Wright JA, Kleiman E, Khan WN, Wen R, Wang D) J Immunol 2012 Dec 01;189(11):5185-93       18 Citations
1Electro-acupuncture upregulates CGRP expression after rat spinal cord transection. (Li WJ, Li SM, Ding Y, He B, Keegan J, Dong H, Ruan JW, Zeng YS) Neurochem Int 2012 Dec;61(8):1397-403       27 Citations
2Inflammatory signals direct expression of human IL12RB1 into multiple distinct isoforms. (Ford NR, Miller HE, Reeme AE, Waukau J, Bengtson C, Routes JM, Robinson RT) J Immunol 2012 Nov 01;189(9):4684-94       19 Citations
1Uncovering transcription factor modules using one- and three-dimensional analyses. (Lan X, Farnham PJ, Jin VX) J Biol Chem 2012 Sep 07;287(37):30914-21       6 Citations
1Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype. (Yuan B, Feng JQ, Bowman S, Liu Y, Blank RD, Lindberg I, Drezner MK) J Bone Miner Res 2013 Jan;28(1):56-72       58 Citations
2LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. (Mammoto T, Chen J, Jiang E, Jiang A, Smith LE, Ingber DE, Mammoto A) PLoS One 2012;7(7):e41596       32 Citations
1A novel SGLT is expressed in the human kidney. (Kothinti RK, Blodgett AB, North PE, Roman RJ, Tabatabai NM) Eur J Pharmacol 2012 Sep 05;690(1-3):77-83       28 Citations
2Subcongenic analyses reveal complex interactions between distal chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in nonobese diabetic mice. (Stolp J, Chen YG, Cox SL, Henck V, Zhang W, Tsaih SW, Chapman H, Stearns T, Serreze DV, Silveira PA) J Immunol 2012 Aug 01;189(3):1406-17       12 Citations
1Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy. (Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN) PLoS One 2012;7(6):e39113       128 Citations
1The timing of multiple retrieval events can alter GluR1 phosphorylation and the requirement for protein synthesis in fear memory reconsolidation. (Jarome TJ, Kwapis JL, Werner CT, Parsons RG, Gafford GM, Helmstetter FJ) Learn Mem 2012 Jun 20;19(7):300-6       43 Citations
5Intestinal alkaline phosphatase administration in newborns is protective of gut barrier function in a neonatal necrotizing enterocolitis rat model. (Rentea RM, Liedel JL, Welak SR, Cassidy LD, Mayer AN, Pritchard KA Jr, Oldham KT, Gourlay DM) J Pediatr Surg 2012 Jun;47(6):1135-42       50 Citations
1The neural plasticity of early-passage human bone marrow-derived mesenchymal stem cells and their modulation with chromatin-modifying agents. (Zhang Z, Alexanian AR) J Tissue Eng Regen Med 2014 May;8(5):407-13       11 Citations
1Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages. (Lan X, Witt H, Katsumura K, Ye Z, Wang Q, Bresnick EH, Farnham PJ, Jin VX) Nucleic Acids Res 2012 Sep;40(16):7690-704       92 Citations
1JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia. (Cayo MA, Cai J, DeLaForest A, Noto FK, Nagaoka M, Clark BS, Collery RF, Si-Tayeb K, Duncan SA) Hepatology 2012 Dec;56(6):2163-71       123 Citations
1Gene trapping uncovers sex-specific mechanisms for upstream stimulatory factors 1 and 2 in angiotensinogen expression. (Park S, Liu X, Davis DR, Sigmund CD) Hypertension 2012 Jun;59(6):1212-9       12 Citations
1Glycerol accumulation in edema formation following diffuse traumatic brain injury. (Ali A, Konakondla S, Zwagerman NT, Peng C, Schafer S, Ding JY, Dornbos D 3rd, Sikharam C, Geng X, Guthikonda M, Kreipke CW, Rafols JA, Ding Y) Neurol Res 2012 Jun;34(5):462-8       5 Citations
1ROCK1 feedback regulation of the upstream small GTPase RhoA. (Tang AT, Campbell WB, Nithipatikom K) Cell Signal 2012 Jul;24(7):1375-80       35 Citations
1Regulation of acute graft-versus-host disease by microRNA-155. (Ranganathan P, Heaphy CE, Costinean S, Stauffer N, Na C, Hamadani M, Santhanam R, Mao C, Taylor PA, Sandhu S, He G, Shana'ah A, Nuovo GJ, Lagana A, Cascione L, Obad S, Broom O, Kauppinen S, Byrd JC, Caligiuri M, Perrotti D, Hadley GA, Marcucci G, Devine SM, Blazar BR, Croce CM, Garzon R) Blood 2012 May 17;119(20):4786-97       131 Citations
1Tetanus toxin and botulinum toxin a utilize unique mechanisms to enter neurons of the central nervous system. (Blum FC, Chen C, Kroken AR, Barbieri JT) Infect Immun 2012 May;80(5):1662-9       58 Citations
2Expression of high-affinity IgE receptor on human peripheral blood dendritic cells in children. (Vasudev M, Cheung DS, Pincsak H, Li SH, Yan K, Simpson P, Dasu T, Grayson MH) PLoS One 2012;7(2):e32556       28 Citations
1Toxicogenomic analysis of a sustained release local anesthetic delivery system. (Shichor I, Shomron N, Lawlor MW, Bae SA, Zoldan J, Langer R, Kohane DS) Biomaterials 2012 May;33(13):3586-93       11 Citations
1Angiotensin converting enzyme inhibitors mitigate collagen synthesis induced by a single dose of radiation to the whole thorax. (Kma L, Gao F, Fish BL, Moulder JE, Jacobs ER, Medhora M) J Radiat Res 2012;53(1):10-7       62 Citations
1Genetic mapping of habitual substance use, obesity-related traits, responses to mental and physical stress, and heart rate and blood pressure measurements reveals shared genes that are overrepresented in the neural synapse. (Nikpay M, Šeda O, Tremblay J, Petrovich M, Gaudet D, Kotchen TA, Cowley AW Jr, Hamet P) Hypertens Res 2012 Jun;35(6):585-91       39 Citations
1Regulation of renin expression by the orphan nuclear receptors Nr2f2 and Nr2f6. (Weatherford ET, Liu X, Sigmund CD) Am J Physiol Renal Physiol 2012 Apr 15;302(8):F1025-33       12 Citations
1Proteinase 3 contributes to transendothelial migration of NB1-positive neutrophils. (Kuckleburg CJ, Tilkens SB, Santoso S, Newman PJ) J Immunol 2012 Mar 01;188(5):2419-26       66 Citations
1Impaired adaptation of gastrointestinal motility following chronic stress in maternally separated rats. (Bülbül M, Babygirija R, Cerjak D, Yoshimoto S, Ludwig K, Takahashi T) Am J Physiol Gastrointest Liver Physiol 2012 Apr;302(7):G702-11       24 Citations
1Cholesterol and lipoprotein dynamics in a hibernating mammal. (Otis JP, Sahoo D, Drover VA, Yen CL, Carey HV) PLoS One 2011;6(12):e29111       33 Citations
1AAV-mediated gene transfer of human X-linked inhibitor of apoptosis protects against oxidative cell death in human RPE cells. (Shan H, Ji D, Barnard AR, Lipinski DM, You Q, Lee EJ, Kamalden TA, Sun X, MacLaren RE) Invest Ophthalmol Vis Sci 2011 Dec 20;52(13):9591-7       17 Citations
1Techniques for following the movement of single RNAs in living cells. (Urbinati CR, Long RM) Wiley Interdiscip Rev RNA 2011;2(4):601-9       16 Citations
1Stimulation of the hypothalamic ventromedial nuclei by pituitary adenylate cyclase-activating polypeptide induces hypophagia and thermogenesis. (Resch JM, Boisvert JP, Hourigan AE, Mueller CR, Yi SS, Choi S) Am J Physiol Regul Integr Comp Physiol 2011 Dec;301(6):R1625-34       61 Citations
1Optimization of hCFTR lung expression in mice using DNA nanoparticles. (Padegimas L, Kowalczyk TH, Adams S, Gedeon CR, Oette SM, Dines K, Hyatt SL, Sesenoglu-Laird O, Tyr O, Moen RC, Cooper MJ) Mol Ther 2012 Jan;20(1):63-72       33 Citations
1BB rat Gimap gene expression in sorted lymphoid T and B cells. (Moralejo DH, Fuller JM, Rutledge EA, Van Yserloo B, Ettinger RA, Jensen R, Osborne W, Kwitek A, Lernmark A) Life Sci 2011 Nov 07;89(19-20):748-54       10 Citations
1MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression. (Xiao TZ, Bhatia N, Urrutia R, Lomberk GA, Simpson A, Longley BJ) PLoS One 2011;6(8):e23747       40 Citations
1PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3. (Strungaru MH, Footz T, Liu Y, Berry FB, Belleau P, Semina EV, Raymond V, Walter MA) Invest Ophthalmol Vis Sci 2011 Sep 29;52(10):7625-33       27 Citations
1Vav protein guanine nucleotide exchange factor regulates CD36 protein-mediated macrophage foam cell formation via calcium and dynamin-dependent processes. (Rahaman SO, Zhou G, Silverstein RL) J Biol Chem 2011 Oct 14;286(41):36011-36019       42 Citations
1Similarities and differences between two modes of antagonism of the thyroid hormone receptor. (Sadana P, Hwang JY, Attia RR, Arnold LA, Neale G, Guy RK) ACS Chem Biol 2011 Oct 21;6(10):1096-106       18 Citations
1Genetics of anterior segment dysgenesis disorders. (Reis LM, Semina EV) Curr Opin Ophthalmol 2011 Sep;22(5):314-24       134 Citations
1Differential expression of MMP-2 and -9 and their inhibitors in fetal lung cells exposed to mechanical stretch: regulation by IL-10. (Hawwa RL, Hokenson MA, Wang Y, Huang Z, Sharma S, Sanchez-Esteban J) Lung 2011 Aug;189(4):341-9       19 Citations
1Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice. (Leduc MS, Hageman RS, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B) J Lipid Res 2011 Sep;52(9):1672-82       22 Citations
1The Borrelia burgdorferi integrin ligand P66 affects gene expression by human cells in culture. (LaFrance ME, Pierce JV, Antonara S, Coburn J) Infect Immun 2011 Aug;79(8):3249-61       18 Citations
1Instability of Foxp3 expression limits the ability of induced regulatory T cells to mitigate graft versus host disease. (Beres A, Komorowski R, Mihara M, Drobyski WR) Clin Cancer Res 2011 Jun 15;17(12):3969-83       81 Citations
1Mouse Rankl expression is regulated in T cells by c-Fos through a cluster of distal regulatory enhancers designated the T cell control region. (Bishop KA, Coy HM, Nerenz RD, Meyer MB, Pike JW) J Biol Chem 2011 Jun 10;286(23):20880-91       47 Citations
1Platelet CD36 surface expression levels affect functional responses to oxidized LDL and are associated with inheritance of specific genetic polymorphisms. (Ghosh A, Murugesan G, Chen K, Zhang L, Wang Q, Febbraio M, Anselmo RM, Marchant K, Barnard J, Silverstein RL) Blood 2011 Jun 09;117(23):6355-66       109 Citations
1Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model. (Gehrking KM, Andresen JM, Duvick L, Lough J, Zoghbi HY, Orr HT) Hum Mol Genet 2011 Jun 01;20(11):2204-12       56 Citations
1Hypothalamic oxytocin attenuates CRF expression via GABA(A) receptors in rats. (Bülbül M, Babygirija R, Cerjak D, Yoshimoto S, Ludwig K, Takahashi T) Brain Res 2011 Apr 28;1387:39-45       66 Citations
2Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. (Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F) FASEB J 2011 Jun;25(6):1844-55       39 Citations
1Functional analysis of KAP1 genomic recruitment. (Iyengar S, Ivanov AV, Jin VX, Rauscher FJ 3rd, Farnham PJ) Mol Cell Biol 2011 May;31(9):1833-47       96 Citations
2Analysis of proteome changes in doxorubicin-treated adult rat cardiomyocyte. (Kumar SN, Konorev EA, Aggarwal D, Kalyanaraman B) J Proteomics 2011 May 01;74(5):683-97       31 Citations
1Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation. (Wuerzberger-Davis SM, Chen Y, Yang DT, Kearns JD, Bates PW, Lynch C, Ladell NC, Yu M, Podd A, Zeng H, Huang TT, Wen R, Hoffmann A, Wang D, Miyamoto S) Immunity 2011 Feb 25;34(2):188-200       33 Citations
1Natural antisense transcript: a concomitant engagement with protein-coding transcript. (Li K, Ramchandran R) Oncotarget 2010 Oct;1(6):447-52       54 Citations
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1Adrenocorticotropic hormone and corticosterone responses to acute hypoxia in the neonatal rat: effects of body temperature maintenance. (Bruder ED, Kamer KJ, Guenther MA, Raff H) Am J Physiol Regul Integr Comp Physiol 2011 Mar;300(3):R708-15       19 Citations
2Effect of high-dose total body irradiation on ACTH, corticosterone, and catecholamines in the rat. (Cohen EP, Bruder ED, Cullinan WE, Ziegler D, Raff H) Transl Res 2011 Jan;157(1):38-47       8 Citations
1An efficient method for generation of neural-like cells from adult human bone marrow-derived mesenchymal stem cells. (Alexanian AR) Regen Med 2010 Nov;5(6):891-900       33 Citations
2Natural and synthetic corticosteroids inhibit uptake 2-mediated transport in CNS neurons. (Hill JE, Makky K, Shrestha L, Hillard CJ, Gasser PJ) Physiol Behav 2011 Aug 03;104(2):306-11       27 Citations
1Gene and noncoding RNA regulation underlying photoreceptor protection: microarray study of dietary antioxidant saffron and photobiomodulation in rat retina. (Natoli R, Zhu Y, Valter K, Bisti S, Eells J, Stone J) Mol Vis 2010 Sep 03;16:1801-22       120 Citations
1Fragmentation of the large subunit ribosomal RNA gene in oyster mitochondrial genomes. (Milbury CA, Lee JC, Cannone JJ, Gaffney PM, Gutell RR) BMC Genomics 2010 Sep 02;11:485       16 Citations
1TRPA1 mediates mechanical currents in the plasma membrane of mouse sensory neurons. (Vilceanu D, Stucky CL) PLoS One 2010 Aug 16;5(8):e12177       126 Citations
1Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. (Evers DM, Matta JA, Hoe HS, Zarkowsky D, Lee SH, Isaac JT, Pak DT) Nat Neurosci 2010 Oct;13(10):1199-207       59 Citations
1Vagal nerve stimulation protects against burn-induced intestinal injury through activation of enteric glia cells. (Costantini TW, Bansal V, Krzyzaniak M, Putnam JG, Peterson CY, Loomis WH, Wolf P, Baird A, Eliceiri BP, Coimbra R) Am J Physiol Gastrointest Liver Physiol 2010 Dec;299(6):G1308-18       142 Citations
1Hypothalamic oxytocin mediates adaptation mechanism against chronic stress in rats. (Zheng J, Babygirija R, Bülbül M, Cerjak D, Ludwig K, Takahashi T) Am J Physiol Gastrointest Liver Physiol 2010 Oct;299(4):G946-53       94 Citations
1Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat. (Kaldunski M, Jia S, Geoffrey R, Basken J, Prosser S, Kansra S, Mordes JP, Lernmark A, Wang X, Hessner MJ) Diabetes 2010 Oct;59(10):2375-85       27 Citations
1SLC26A9 stimulates CFTR expression and function in human bronchial cell lines. (Avella M, Loriol C, Boulukos K, Borgese F, Ehrenfeld J) J Cell Physiol 2011 Jan;226(1):212-23       62 Citations
1Beneficial effects of social attachment to overcome daily stress. (Babygirija R, Zheng J, Bülbül M, Ludwig K, Takahashi T) Brain Res 2010 Sep 17;1352:43-9       18 Citations
1Time-dependent expression of Arc and zif268 after acquisition of fear conditioning. (Lonergan ME, Gafford GM, Jarome TJ, Helmstetter FJ) Neural Plast 2010;2010:139891       95 Citations
1Deficiency of telomerase activity aggravates the blood-brain barrier disruption and neuroinflammatory responses in a model of experimental stroke. (Zhang B, Chen L, Swartz KR, Bruemmer D, Eum SY, Huang W, Seelbach M, Choi YJ, Hennig B, Toborek M) J Neurosci Res 2010 Oct;88(13):2859-68       34 Citations
1Involvement of reductive stress in the cardiomyopathy in transgenic mice with cardiac-specific overexpression of heat shock protein 27. (Zhang X, Min X, Li C, Benjamin IJ, Qian B, Zhang X, Ding Z, Gao X, Yao Y, Ma Y, Cheng Y, Liu L) Hypertension 2010 Jun;55(6):1412-7       108 Citations
1The integrin co-activator Kindlin-3 is expressed and functional in a non-hematopoietic cell, the endothelial cell. (Bialkowska K, Ma YQ, Bledzka K, Sossey-Alaoui K, Izem L, Zhang X, Malinin N, Qin J, Byzova T, Plow EF) J Biol Chem 2010 Jun 11;285(24):18640-9       90 Citations
1The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation. (Mangos S, Lam PY, Zhao A, Liu Y, Mudumana S, Vasilyev A, Liu A, Drummond IA) Dis Model Mech 2010;3(5-6):354-65       119 Citations
1Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-{kappa}B. (Rafiee P, Binion DG, Wellner M, Behmaram B, Floer M, Mitton E, Nie L, Zhang Z, Otterson MF) Am J Physiol Gastrointest Liver Physiol 2010 Jun;298(6):G865-77       48 Citations
1Emerging regulatory paradigms for control of gene expression by 1,25-dihydroxyvitamin D3. (Pike JW, Meyer MB, Martowicz ML, Bishop KA, Lee SM, Nerenz RD, Goetsch PD) J Steroid Biochem Mol Biol 2010 Jul;121(1-2):130-5       51 Citations
1The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. (Yang X, Lu X, Lombès M, Rha GB, Chi YI, Guerin TM, Smart EJ, Liu J) Cell Metab 2010 Mar 03;11(3):194-205       427 Citations
2Expression of natural killer receptors in T- and NK-cells: comparison of healthy individuals, patients with prior stem cell transplant, and patients undergoing chemotherapy. (Olteanu H, Schur BC, Bredeson C, Atallah E, Kroft SH) Leuk Lymphoma 2010 Mar;51(3):481-7       5 Citations
1Tuba1a gene expression is regulated by KLF6/7 and is necessary for CNS development and regeneration in zebrafish. (Veldman MB, Bemben MA, Goldman D) Mol Cell Neurosci 2010 Apr;43(4):370-83       59 Citations
1Increased renin production in mice with deletion of peroxisome proliferator-activated receptor-gamma in juxtaglomerular cells. (Desch M, Schreiber A, Schweda F, Madsen K, Friis UG, Weatherford ET, Sigmund CD, Sequeira Lopez ML, Gomez RA, Todorov VT) Hypertension 2010 Mar;55(3):660-6       24 Citations
1Endothelial and vascular muscle PPARgamma in arterial pressure regulation: lessons from genetic interference and deficiency. (Sigmund CD) Hypertension 2010 Feb;55(2):437-44       38 Citations
1Qualitative effect on mRNAs of injury-associated proteins by cell phone like radiation in rat facial nerves. (Yan JG, Agresti M, Zhang LL, Yan Y, Matloub HS) Electromagn Biol Med 2009;28(4):383-90       13 Citations
2E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. (Chong JL, Wenzel PL, Sáenz-Robles MT, Nair V, Ferrey A, Hagan JP, Gomez YM, Sharma N, Chen HZ, Ouseph M, Wang SH, Trikha P, Culp B, Mezache L, Winton DJ, Sansom OJ, Chen D, Bremner R, Cantalupo PG, Robinson ML, Pipas JM, Leone G) Nature 2009 Dec 17;462(7275):930-4       207 Citations
1Dynamic convergence and divergence of renal genomic and biological pathways in protection from Dahl salt-sensitive hypertension. (Lu L, Li P, Yang C, Kurth T, Misale M, Skelton M, Moreno C, Roman RJ, Greene AS, Jacob HJ, Lazar J, Liang M, Cowley AW Jr) Physiol Genomics 2010 Mar 03;41(1):63-70       29 Citations
1Brucella melitensis, B. neotomae and B. ovis elicit common and distinctive macrophage defense transcriptional responses. (Covert J, Mathison AJ, Eskra L, Banai M, Splitter G) Exp Biol Med (Maywood) 2009 Dec;234(12):1450-67       33 Citations
1Expression of herpes virus entry mediator (HVEM) in the cornea and trigeminal ganglia of normal and HSV-1 infected mice. (Kovacs SK, Tiwari V, Prandovszky E, Dosa S, Bacsa S, Valyi-Nagy K, Shukla D, Valyi-Nagy T) Curr Eye Res 2009 Oct;34(10):896-904       24 Citations
1Genomic targets of the KRAB and SCAN domain-containing zinc finger protein 263. (Frietze S, Lan X, Jin VX, Farnham PJ) J Biol Chem 2010 Jan 08;285(2):1393-403       88 Citations
2A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo. (Li K, Blum Y, Verma A, Liu Z, Pramanik K, Leigh NR, Chun CZ, Samant GV, Zhao B, Garnaas MK, Horswill MA, Stanhope SA, North PE, Miao RQ, Wilkinson GA, Affolter M, Ramchandran R) Blood 2010 Jan 07;115(1):133-9       142 Citations
1Febrile-range temperature modifies cytokine gene expression in LPS-stimulated macrophages by differentially modifying NF-{kappa}B recruitment to cytokine gene promoters. (Cooper ZA, Ghosh A, Gupta A, Maity T, Benjamin IJ, Vogel SN, Hasday JD, Singh IS) Am J Physiol Cell Physiol 2010 Jan;298(1):C171-81       37 Citations
2Paper-supported 3D cell culture for tissue-based bioassays. (Derda R, Laromaine A, Mammoto A, Tang SK, Mammoto T, Ingber DE, Whitesides GM) Proc Natl Acad Sci U S A 2009 Nov 03;106(44):18457-62       412 Citations
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1Repair of nitric oxide-damaged DNA in beta-cells requires JNK-dependent GADD45alpha expression. (Hughes KJ, Meares GP, Chambers KT, Corbett JA) J Biol Chem 2009 Oct 02;284(40):27402-8       38 Citations
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1Inhibition of CDKS by roscovitine suppressed LPS-induced *NO production through inhibiting NFkappaB activation and BH4 biosynthesis in macrophages. (Du J, Wei N, Guan T, Xu H, An J, Pritchard KA Jr, Shi Y) Am J Physiol Cell Physiol 2009 Sep;297(3):C742-9       44 Citations
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2Increased superoxide production contributes to the impaired angiogenesis of fetal pulmonary arteries with in utero pulmonary hypertension. (Teng RJ, Eis A, Bakhutashvili I, Arul N, Konduri GG) Am J Physiol Lung Cell Mol Physiol 2009 Jul;297(1):L184-95       66 Citations
1The enhanced hypercalcemic response to 20-epi-1,25-dihydroxyvitamin D3 results from a selective and prolonged induction of intestinal calcium-regulating genes. (Zella LA, Meyer MB, Nerenz RD, Pike JW) Endocrinology 2009 Aug;150(8):3448-56       25 Citations
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1The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation. (Lin YS, Yasuda K, Assem M, Cline C, Barber J, Li CW, Kholodovych V, Ai N, Chen JD, Welsh WJ, Ekins S, Schuetz EG) Drug Metab Dispos 2009 Jun;37(6):1295-304       43 Citations
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1Expression of macrophage migration inhibitory factor by neuroblastoma leads to the inhibition of antitumor T cell reactivity in vivo. (Zhou Q, Yan X, Gershan J, Orentas RJ, Johnson BD) J Immunol 2008 Aug 01;181(3):1877-86       37 Citations
1Dysregulated human renin expression in transgenic mice carrying truncated genomic constructs: evidence supporting the presence of insulators at the renin locus. (Zhou X, Weatherford ET, Liu X, Born E, Keen HL, Sigmund CD) Am J Physiol Renal Physiol 2008 Sep;295(3):F642-53       3 Citations
2Activation of the A(3) adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils. (van der Hoeven D, Wan TC, Auchampach JA) Mol Pharmacol 2008 Sep;74(3):685-96       72 Citations
1Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement. (Wang D, Chen H, Momary KM, Cavallari LH, Johnson JA, Sadée W) Blood 2008 Aug 15;112(4):1013-21       190 Citations
2Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic rats. (Liang M, Lee NH, Wang H, Greene AS, Kwitek AE, Kaldunski ML, Luu TV, Frank BC, Bugenhagen S, Jacob HJ, Cowley AW Jr) Physiol Genomics 2008 Jun 12;34(1):54-64       43 Citations
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1Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. (Meadows SK, Dressman HK, Muramoto GG, Himburg H, Salter A, Wei Z, Ginsburg GS, Chao NJ, Nevins JR, Chute JP) PLoS One 2008 Apr 02;3(4):e1912       109 Citations
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1Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. (Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, Lee JH, Khadem S, Ren S, Li S, Silverstein RL, Xie W) Gastroenterology 2008 Feb;134(2):556-67       553 Citations
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1Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration. (Veldman MB, Bemben MA, Thompson RC, Goldman D) Dev Biol 2007 Dec 15;312(2):596-612       147 Citations
1Dynamic regulation of fluorescent proteins from a single species of coral. (Kao HT, Sturgis S, DeSalle R, Tsai J, Davis D, Gruber DF, Pieribone VA) Mar Biotechnol (NY) 2007;9(6):733-46       14 Citations
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1Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration. (Tan Z, Sun X, Hou FS, Oh HW, Hilgenberg LG, Hol EM, van Leeuwen FW, Smith MA, O'Dowd DK, Schreiber SS) Cell Death Differ 2007 Oct;14(10):1721-32       75 Citations
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1A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression. (Marzolini C, Tirona RG, Gervasini G, Poonkuzhali B, Assem M, Lee W, Leake BF, Schuetz JD, Schuetz EG, Kim RB) Mol Endocrinol 2007 Aug;21(8):1769-80       68 Citations
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1Serotonin 5-HT1A receptor stimulates c-Jun N-terminal kinase and induces apoptosis in Chinese hamster ovary fibroblasts. (Turner JH, Garnovskaya MN, Raymond JR) Biochim Biophys Acta 2007 Mar;1773(3):391-9       26 Citations
1E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop. (Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G) Mol Cell Biol 2007 Jan;27(1):65-78       89 Citations
1ADME transcriptome in Hispanic versus White donor livers: evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics. (Finkelstein D, Lamba V, Assem M, Rengelshausen J, Yasuda K, Strom S, Schuetz E) Xenobiotica 2006;36(10-11):989-1012       12 Citations
1The human renin kidney enhancer is required to maintain base-line renin expression but is dispensable for tissue-specific, cell-specific, and regulated expression. (Zhou X, Davis DR, Sigmund CD) J Biol Chem 2006 Nov 17;281(46):35296-304       33 Citations
1Interleukin-1beta attenuates renin gene expression via a mitogen-activated protein kinase kinase-extracellular signal-regulated kinase and signal transducer and activator of transcription 3-dependent mechanism in As4.1 cells. (Liu X, Shi Q, Sigmund CD) Endocrinology 2006 Dec;147(12):6011-8       25 Citations
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2Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in rats. (Wang C, Weihrauch D, Schwabe DA, Bienengraeber M, Warltier DC, Kersten JR, Pratt PF Jr, Pagel PS) Anesth Analg 2006 Aug;103(2):281-8, table of contents       75 Citations
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1A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding. (Arnold LA, Estébanez-Perpiñá E, Togashi M, Shelat A, Ocasio CA, McReynolds AC, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK) Sci STKE 2006 Jun 27;2006(341):pl3       29 Citations
2Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27. (Rafiee P, Theriot ME, Nelson VM, Heidemann J, Kanaa Y, Horowitz SA, Rogaczewski A, Johnson CP, Ali I, Shaker R, Binion DG) Am J Physiol Cell Physiol 2006 Nov;291(5):C931-45       84 Citations
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1Involvement of the endocannabinoid system in the ability of long-term tricyclic antidepressant treatment to suppress stress-induced activation of the hypothalamic-pituitary-adrenal axis. (Hill MN, Ho WS, Sinopoli KJ, Viau V, Hillard CJ, Gorzalka BB) Neuropsychopharmacology 2006 Dec;31(12):2591-9       111 Citations
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1Strategies for delaying or treating in vivo acquired resistance to trastuzumab in human breast cancer xenografts. (du Manoir JM, Francia G, Man S, Mossoba M, Medin JA, Viloria-Petit A, Hicklin DJ, Emmenegger U, Kerbel RS) Clin Cancer Res 2006 Feb 01;12(3 Pt 1):904-16       131 Citations
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1Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-alpha responsive promoters. (Cheng AS, Jin VX, Fan M, Smith LT, Liyanarachchi S, Yan PS, Leu YW, Chan MW, Plass C, Nephew KP, Davuluri RV, Huang TH) Mol Cell 2006 Feb 03;21(3):393-404       160 Citations
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1RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues. (Wilber A, Frandsen JL, Geurts JL, Largaespada DA, Hackett PB, McIvor RS) Mol Ther 2006 Mar;13(3):625-30       109 Citations
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1Characterization of a muscle-specific enhancer in human MuSK promoter reveals the essential role of myogenin in controlling activity-dependent gene regulation. (Tang H, Veldman MB, Goldman D) J Biol Chem 2006 Feb 17;281(7):3943-53       23 Citations
1The family feud: turning off Sp1 by Sp1-like KLF proteins. (Lomberk G, Urrutia R) Biochem J 2005 Nov 15;392(Pt 1):1-11       177 Citations
1Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli. (Mogil JS, Breese NM, Witty MF, Ritchie J, Rainville ML, Ase A, Abbadi N, Stucky CL, Séguéla P) J Neurosci 2005 Oct 26;25(43):9893-901       115 Citations
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1Long-term therapy with the acorn cardiac support device normalizes gene expression of growth factors and gelatinases in dogs with heart failure. (Rastogi S, Gupta RC, Mishra S, Morita H, Tanhehco EJ, Sabbah HN) J Heart Lung Transplant 2005 Oct;24(10):1619-25       22 Citations
1Is nuclear respiratory factor 2 a master transcriptional coordinator for all ten nuclear-encoded cytochrome c oxidase subunits in neurons? (Ongwijitwat S, Wong-Riley MT) Gene 2005 Oct 24;360(1):65-77       94 Citations
1Encephalomyocarditis virus induces PKR-independent mitogen-activated protein kinase activation in macrophages. (Moran JM, Moxley MA, Buller RM, Corbett JA) J Virol 2005 Aug;79(16):10226-36       24 Citations
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1Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium. (Kalivendi SV, Konorev EA, Cunningham S, Vanamala SK, Kaji EH, Joseph J, Kalyanaraman B) Biochem J 2005 Jul 15;389(Pt 2):527-39       193 Citations
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1A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo. (Ebert AD, Chen F, He X, Cryns VL, Bohn MC) Exp Neurol 2005 Feb;191 Suppl 1:S80-94       18 Citations
1Molecular cloning, localization and circadian expression of chicken melanopsin (Opn4): differential regulation of expression in pineal and retinal cell types. (Chaurasia SS, Rollag MD, Jiang G, Hayes WP, Haque R, Natesan A, Zatz M, Tosini G, Liu C, Korf HW, Iuvone PM, Provencio I) J Neurochem 2005 Jan;92(1):158-70       186 Citations
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1Aberrant regulation of survivin by the RB/E2F family of proteins. (Jiang Y, Saavedra HI, Holloway MP, Leone G, Altura RA) J Biol Chem 2004 Sep 24;279(39):40511-20       153 Citations
1Regulation of photoreceptor Per1 and Per2 by light, dopamine and a circadian clock. (Besharse JC, Zhuang M, Freeman K, Fogerty J) Eur J Neurosci 2004 Jul;20(1):167-74       41 Citations
1Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. (Grossman WJ, Verbsky JW, Tollefsen BL, Kemper C, Atkinson JP, Ley TJ) Blood 2004 Nov 01;104(9):2840-8       441 Citations
1Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences. (Lamba JK, Lamba V, Yasuda K, Lin YS, Assem M, Thompson E, Strom S, Schuetz E) J Pharmacol Exp Ther 2004 Nov;311(2):811-21       98 Citations
1Endotoxin induces an exaggerated interleukin-10 response in peritoneal macrophages of children compared with adults. (Barsness KA, Bensard DD, Partrick DA, Calkins CM, Hendrickson RJ, McIntyre RC Jr) J Pediatr Surg 2004 Jun;39(6):912-5; discussion 912-5       31 Citations
1Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. (Mosley AL, Corbett JA, Ozcan S) Mol Endocrinol 2004 Sep;18(9):2279-90       103 Citations
2Traumatic brain injury increases TGF beta RII expression on endothelial cells. (Fee DB, Sewell DL, Andresen K, Jacques TJ, Piaskowski S, Barger BA, Hart MN, Fabry Z) Brain Res 2004 Jun 25;1012(1-2):52-9       28 Citations
1Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells. (Li WG, Gavrila D, Liu X, Wang L, Gunnlaugsson S, Stoll LL, McCormick ML, Sigmund CD, Tang C, Weintraub NL) Circulation 2004 May 11;109(18):2221-6       488 Citations
2Inhibition of nitrosylation, nitration, lymphocyte proliferation, and gene expression in acute and delayed cardiac allograft rejection by an orally active dithiocarbamate. (Pieper GM, Khanna AK, Kampalath BN, Felix CC, Hilton G, Johnson CP, Adams MB, Roza AM) J Cardiovasc Pharmacol 2004 Apr;43(4):522-30       10 Citations
1Gene expression profiling of potential PPARgamma target genes in mouse aorta. (Keen HL, Ryan MJ, Beyer A, Mathur S, Scheetz TE, Gackle BD, Faraci FM, Casavant TL, Sigmund CD) Physiol Genomics 2004 Jun 17;18(1):33-42       45 Citations
1Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. (Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD) J Biol Chem 2004 May 21;279(21):22250-7       229 Citations
1The role and regulation of COX-2 during viral infection. (Steer SA, Corbett JA) Viral Immunol 2003;16(4):447-60       124 Citations
1Differential expression of the closely linked KISS1, REN, and FLJ10761 genes in transgenic mice. (Nistala R, Zhang X, Sigmund CD) Physiol Genomics 2004 Mar 12;17(1):4-10       10 Citations
1Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor. (Fiaschi-Taesch NM, Santos S, Reddy V, Van Why SK, Philbrick WF, Ortega A, Esbrit P, Orloff JJ, Garcia-Ocaña A) J Am Soc Nephrol 2004 Jan;15(1):112-25       55 Citations
1Unexpected sensitivity of synthetic Renilla luciferase control vectors to treatment with a cyclopentenone prostaglandin. (Zhang X, Chen HZ, Rovin BH) Biotechniques 2003 Dec;35(6):1144-6, 1148       4 Citations
1Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation. (Schmidt C, Peng B, Li Z, Sclabas GM, Fujioka S, Niu J, Schmidt-Supprian M, Evans DB, Abbruzzese JL, Chiao PJ) Mol Cell 2003 Nov;12(5):1287-300       148 Citations
1Cleavage of preflagellins by an aspartic acid signal peptidase is essential for flagellation in the archaeon Methanococcus voltae. (Bardy SL, Jarrell KF) Mol Microbiol 2003 Nov;50(4):1339-47       109 Citations
1Neuronal activity regulates protein and gene expressions of GluR2 in postnatal rat visual cortical neurons in culture. (Bai X, Wong-Riley MT) J Neurocytol 2003 Jan;32(1):71-8       26 Citations
1Alterations in subcellular localization of p38 MAPK potentiates endothelin-stimulated COX-2 expression in glomerular mesangial cells. (Pratt PF, Bokemeyer D, Foschi M, Sorokin A, Dunn MJ) J Biol Chem 2003 Dec 19;278(51):51928-36       38 Citations
1Butyrate modulates gene and protein expression in human intestinal endothelial cells. (Ogawa H, Rafiee P, Fisher PJ, Johnson NA, Otterson MF, Binion DG) Biochem Biophys Res Commun 2003 Sep 26;309(3):512-9       62 Citations
1Adenovirus DNA binding protein inhibits SrCap-activated CBP and CREB-mediated transcription. (Xu X, Tarakanova V, Chrivia J, Yaciuk P) Virology 2003 Sep 01;313(2):615-21       4 Citations
1JUMONJI, a critical factor for cardiac development, functions as a transcriptional repressor. (Kim TG, Kraus JC, Chen J, Lee Y) J Biol Chem 2003 Oct 24;278(43):42247-55       83 Citations
1CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins. (Prosser S, Sorokina E, Pratt P, Sorokin A) Oncogene 2003 Jul 31;22(31):4799-806       27 Citations
1Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. (de Bruin A, Maiti B, Jakoi L, Timmers C, Buerki R, Leone G) J Biol Chem 2003 Oct 24;278(43):42041-9       184 Citations
1Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. (Grimm DH, Cai Y, Chauvet V, Rajendran V, Zeltner R, Geng L, Avner ED, Sweeney W, Somlo S, Caplan MJ) J Biol Chem 2003 Sep 19;278(38):36786-93       77 Citations
1DNA expression analysis: serial analysis of gene expression, microarrays and kidney disease. (Hayden PS, El-Meanawy A, Schelling JR, Sedor JR) Curr Opin Nephrol Hypertens 2003 Jul;12(4):407-14       16 Citations
1Expression, localization and alternative function of cytoplasmic asparaginyl-tRNA synthetase in Brugia malayi. (Kron M, Petridis M, Milev Y, Leykam J, Härtlein M) Mol Biochem Parasitol 2003 Jun;129(1):33-9       23 Citations
1Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation. (Corey LL, Weirich CS, Benjamin IJ, Kingston RE) Genes Dev 2003 Jun 01;17(11):1392-401       120 Citations
1Production of knockout rats using ENU mutagenesis and a yeast-based screening assay. (Zan Y, Haag JD, Chen KS, Shepel LA, Wigington D, Wang YR, Hu R, Lopez-Guajardo CC, Brose HL, Porter KI, Leonard RA, Hitt AA, Schommer SL, Elegbede AF, Gould MN) Nat Biotechnol 2003 Jun;21(6):645-51       193 Citations
1Temporal-spatial characterization of chicken clock genes: circadian expression in retina, pineal gland, and peripheral tissues. (Chong NW, Chaurasia SS, Haque R, Klein DC, Iuvone PM) J Neurochem 2003 May;85(4):851-60       66 Citations
1Identification of a nuclear orphan receptor (Ear2) as a negative regulator of renin gene transcription. (Liu X, Huang X, Sigmund CD) Circ Res 2003 May 16;92(9):1033-40       57 Citations
1Socially-induced brain 'fertilization': play promotes brain derived neurotrophic factor transcription in the amygdala and dorsolateral frontal cortex in juvenile rats. (Gordon NS, Burke S, Akil H, Watson SJ, Panksepp J) Neurosci Lett 2003 Apr 24;341(1):17-20       92 Citations
1Gene expression reveals vulnerability to oxidative stress and interstitial fibrosis of renal outer medulla to nonhypertensive elevations of ANG II. (Yuan B, Liang M, Yang Z, Rute E, Taylor N, Olivier M, Cowley AW Jr) Am J Physiol Regul Integr Comp Physiol 2003 May;284(5):R1219-30       27 Citations
1A threshold for central T cell tolerance to an inducible serum protein. (Haribhai D, Engle D, Meyer M, Donermeyer D, White JM, Williams CB) J Immunol 2003 Mar 15;170(6):3007-14       21 Citations
1Cannabinoid-induced Fos expression within A10 dopaminergic neurons. (Patel S, Hillard CJ) Brain Res 2003 Feb 14;963(1-2):15-25       58 Citations
1Dual regulation of cryptochrome 1 mRNA expression in chicken retina by light and circadian oscillators. (Haque R, Chaurasia SS, Wessel JH 3rd, Iuvone PM) Neuroreport 2002 Dec 03;13(17):2247-51       94 Citations
1Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression. (Liang M, Yuan B, Rute E, Greene AS, Olivier M, Cowley AW Jr) Physiol Genomics 2003 Feb 06;12(3):229-37       55 Citations
1Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. (Yan LJ, Christians ES, Liu L, Xiao X, Sohal RS, Benjamin IJ) EMBO J 2002 Oct 01;21(19):5164-72       217 Citations
1The function of multiple IkappaB : NF-kappaB complexes in the resistance of cancer cells to Taxol-induced apoptosis. (Dong QG, Sclabas GM, Fujioka S, Schmidt C, Peng B, Wu T, Tsao MS, Evans DB, Abbruzzese JL, McDonnell TJ, Chiao PJ) Oncogene 2002 Sep 19;21(42):6510-9       161 Citations
1Estrous cycle-regulated expression of CYP1B1 mRNA in the rat ovary. (Dasmahapatra AK, Trewin AL, Hutz RJ) Comp Biochem Physiol B Biochem Mol Biol 2002 Sep;133(1):127-34       28 Citations
1Regulation of renin expression and blood pressure by vitamin D(3). (Sigmund CD) J Clin Invest 2002 Jul;110(2):155-6       63 Citations
1Distribution of vesicular glutamate transporter mRNA in rat hypothalamus. (Ziegler DR, Cullinan WE, Herman JP) J Comp Neurol 2002 Jul 01;448(3):217-29       222 Citations
1A molecular basis for differential developmental anomalies in Axenfeld-Rieger syndrome. (Espinoza HM, Cox CJ, Semina EV, Amendt BA) Hum Mol Genet 2002 Apr 01;11(7):743-53       59 Citations
1Induction of chondrocyte growth arrest by FGF: transcriptional and cytoskeletal alterations. (Rozenblatt-Rosen O, Mosonego-Ornan E, Sadot E, Madar-Shapiro L, Sheinin Y, Ginsberg D, Yayon A) J Cell Sci 2002 Feb 01;115(Pt 3):553-62       56 Citations
1Current status of defensins and their role in innate and adaptive immunity. (Raj PA, Dentino AR) FEMS Microbiol Lett 2002 Jan 02;206(1):9-18       231 Citations
1PU.1/Spi-B regulation of c-rel is essential for mature B cell survival. (Hu CJ, Rao S, Ramirez-Bergeron DL, Garrett-Sinha LA, Gerondakis S, Clark MR, Simon MC) Immunity 2001 Oct;15(4):545-55       43 Citations
1Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD. (Sweeney WE Jr, Kusner L, Carlin CR, Chang S, Futey L, Cotton CU, Dell KM, Avner ED) Am J Physiol Cell Physiol 2001 Nov;281(5):C1695-705       22 Citations
1Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression. (Pan L, Black TA, Shi Q, Jones CA, Petrovic N, Loudon J, Kane C, Sigmund CD, Gross KW) J Biol Chem 2001 Dec 07;276(49):45530-8       116 Citations
1Oxygen-dependent expression of hypoxia-inducible factor-1alpha in renal medullary cells of rats. (Zou AP, Yang ZZ, Li PL, Cowley AW JR) Physiol Genomics 2001 Aug 28;6(3):159-68       52 Citations
1Vectors for high-level expression of cDNAs controlled by tissue-specific promoters in transgenic mice. (Stec DE, Morimoto S, Sigmund CD) Biotechniques 2001 Aug;31(2):256-8, 260       16 Citations
1Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease. (Chu Y, Cochran EJ, Bennett DA, Mufson EJ, Kordower JH) J Comp Neurol 2001 Aug 27;437(3):296-307       70 Citations
1Intestinal cytokine gene expression in infants with acute necrotizing enterocolitis: interleukin-11 mRNA expression inversely correlates with extent of disease. (Nadler EP, Stanford A, Zhang XR, Schall LC, Alber SM, Watkins SC, Ford HR) J Pediatr Surg 2001 Aug;36(8):1122-9       75 Citations
1Lack of effect of beta-naphthoflavone on induction of Nramp genes in adult rainbow trout Oncorhynchus mykiss. (Dasmahapatra AK, Wimpee BA, Budsberg KJ, Dorschner MO, Phillips RB, Hutz RJ) Mar Environ Res 2000;50(1-5):147-51    
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1PreproEndothelin-1 expression in human mesangial cells: evidence for a p38 mitogen-activated protein kinase/protein kinases-C-dependent mechanism. (Foschi M, Sorokin A, Pratt P, McGinty A, Villa G, Franchi F, Dunn MJ) J Am Soc Nephrol 2001 Jun;12(6):1137-1150       21 Citations
1PU.1 exhibits partial functional redundancy with Spi-B, but not with Ets-1 or Elf-1. (Garrett-Sinha LA, Dahl R, Rao S, Barton KP, Simon MC) Blood 2001 May 01;97(9):2908-12       49 Citations
1GAP-43 promoter elements in transgenic zebrafish reveal a difference in signals for axon growth during CNS development and regeneration. (Udvadia AJ, Köster RW, Skene JH) Development 2001 Apr;128(7):1175-82       117 Citations
1Paradoxical regulation of short promoter human renin transgene by angiotensin ii. (Keen HL, Sigmund CD) Hypertension 2001 Feb;37(2 Pt 2):403-7       11 Citations
1Androgen-dependent regulation of human angiotensinogen expression in KAP-hAGT transgenic mice. (Ding Y, Sigmund CD) Am J Physiol Renal Physiol 2001 Jan;280(1):F54-60       48 Citations
1Retinoic acid-mediated activation of the mouse renin enhancer. (Shi Q, Gross KW, Sigmund CD) J Biol Chem 2001 Feb 02;276(5):3597-603       59 Citations
1Differential regulation of two period genes in the Xenopus eye. (Zhuang M, Wang Y, Steenhard BM, Besharse JC) Brain Res Mol Brain Res 2000 Oct 20;82(1-2):52-64       53 Citations
1Expression of mPer1 and mPer2, two mammalian clock genes, in murine bone marrow. (Chen YG, Mantalaris A, Bourne P, Keng P, Wu JH) Biochem Biophys Res Commun 2000 Sep 24;276(2):724-8       45 Citations
2Blood group A and B antigens are strongly expressed on platelets of some individuals. (Curtis BR, Edwards JT, Hessner MJ, Klein JP, Aster RH) Blood 2000 Aug 15;96(4):1574-81       120 Citations
1Free radicals upregulate complement expression in rabbit isolated heart. (Tanhehco EJ, Yasojima K, McGeer PL, Washington RA, Lucchesi BR) Am J Physiol Heart Circ Physiol 2000 Jul;279(1):H195-201       28 Citations
1Retinoic acid upregulates beta(1)-integrin in vascular smooth muscle cells and alters adhesion to fibronectin. (Medhora MM) Am J Physiol Heart Circ Physiol 2000 Jul;279(1):H382-7       31 Citations
1CD36 in atherosclerosis. The role of a class B macrophage scavenger receptor. (Nicholson AC, Febbraio M, Han J, Silverstein RL, Hajjar DP) Ann N Y Acad Sci 2000 May;902:128-31; discussion 131-3       69 Citations
1Expression of smooth muscle myosin light chain 17 and unloaded shortening in single smooth muscle cells. (Eddinger TJ, Korwek AA, Meer DP, Sherwood JJ) Am J Physiol Cell Physiol 2000 Jun;278(6):C1133-42       20 Citations
1Calcium and disease: molecular determinants of calcium crystal deposition diseases. (Misra RP) Cell Mol Life Sci 2000 Mar;57(3):421-8       18 Citations
1Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma. (Feng J, Han J, Pearce SF, Silverstein RL, Gotto AM Jr, Hajjar DP, Nicholson AC) J Lipid Res 2000 May;41(5):688-96       230 Citations
1Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins. (Leone G, Nuckolls F, Ishida S, Adams M, Sears R, Jakoi L, Miron A, Nevins JR) Mol Cell Biol 2000 May;20(10):3626-32       163 Citations
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1Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway. (Pirkkala L, Alastalo TP, Zuo X, Benjamin IJ, Sistonen L) Mol Cell Biol 2000 Apr;20(8):2670-5       104 Citations
1Identification of cis elements in the cardiac troponin T gene conferring specific expression in cardiac muscle of transgenic mice. (Wang Q, Sigmund CD, Lin JJ) Circ Res 2000 Mar 03;86(4):478-84       31 Citations
1Phase shifting the retinal circadian clock: xPer2 mRNA induction by light and dopamine. (Steenhard BM, Besharse JC) J Neurosci 2000 Dec 01;20(23):8572-7       56 Citations
1Appropriate tissue- and cell-specific expression of a single copy human angiotensinogen transgene specifically targeted upstream of the HPRT locus by homologous recombination. (Cvetkovic B, Yang B, Williamson RA, Sigmund CD) J Biol Chem 2000 Jan 14;275(2):1073-8       46 Citations
1Preconditioning reduces tissue complement gene expression in the rabbit isolated heart. (Tanhehco EJ, Yasojima K, McGeer PL, Washington RA, Kilgore KS, Homeister JW, Lucchesi BR) Am J Physiol 1999 Dec;277(6):H2373-80       22 Citations
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1Alternative exon splicing of cyclic AMP response element-binding protein in peripheral sensory and sympathetic ganglia of the rat. (Pietruck C, Xie GX, Sharma M, Meuser T, Palmer PP) Life Sci 1999;65(21):2205-13       3 Citations
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1Molecular cloning, tissue-specific expression, and chromosomal localization of a novel nerve growth factor-regulated G-protein- coupled receptor, nrg-1. (Glickman M, Malek RL, Kwitek-Black AE, Jacob HJ, Lee NH) Mol Cell Neurosci 1999 Aug;14(2):141-52       67 Citations
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1Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans. (Heitmeier MR, Scarim AL, Corbett JA) J Biol Chem 1999 Oct 08;274(41):29266-73       67 Citations
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2Integrin alphaIIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells. (Wilcox DA, Olsen JC, Ishizawa L, Griffith M, White GC 2nd) Proc Natl Acad Sci U S A 1999 Aug 17;96(17):9654-9       52 Citations
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1Basic fibroblast growth factor activates serum response factor gene expression by multiple distinct signaling mechanisms. (Spencer JA, Major ML, Misra RP) Mol Cell Biol 1999 Jun;19(6):3977-88       21 Citations
1The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase. (Griffith OW, Mulcahy RT) Adv Enzymol Relat Areas Mol Biol 1999;73:209-67, xii       248 Citations
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1Demonstration and functional analysis of IL-10 receptors in human epidermal cells: decreased expression in psoriatic skin, down-modulation by IL-8, and up-regulation by an antipsoriatic glucocorticosteroid in normal cultured keratinocytes. (Michel G, Mirmohammadsadegh A, Olasz E, Jarzebska-Deussen B, Müschen A, Kemény L, Abts HF, Ruzicka T) J Immunol 1997 Dec 15;159(12):6291-7       69 Citations
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