Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Publications indexed to the term Lymphocyte Activation

FacultyTitle
1Both soluble and cell surface CD137 expressed by Foxp3+ CD4 T cells restrain autoimmune diabetes. (Nabi R, Lin CW, Wang Y, Ciecko AE, Foda BM, Wang Y, Drewek A, Lieberman SM, Ridgway WM, Chen YG) J Exp Med 2026 Aug 03;223(8)    
1Alternate splicing converts human CD137 from costimulatory to immunosuppressive function. (Rojas M, Heuer LS, Zhang W, Sweeney N, Ramírez-Santana C, Leung PSC, Lam A, Kamat S, Mendelsohn AR, Huang M, Yu B, Ackerman P, Wei Q, Larrick JW, Chen YG, Ridgway WM) J Autoimmun 2025 Dec;157:103498       1 Citation
1Human cornea-derived mesenchymal stromal cells inhibit T cells through indoleamine 2,3 dioxygenase. (Faircloth TU, Temple S, Parr R, Soma A, Massoumi H, Jalilian E, Djalilian AR, Hematti P, Rajan D, Chinnadurai R) Cytotherapy 2025 May;27(5):597-608       3 Citations
1Elevated frequencies of activated memory B cells in multiple sclerosis are reset to healthy control levels after B cell depletion with Ocrelizumab. (Gurski CJ, Hajiyeva Z, Veltri AJ, Fenton K, O'Dell S, Obeidat AZ, Dittel BN) J Neuroimmunol 2025 Feb 15;399:578502       9 Citations
1Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling. (Forsyth KS, Toothacre NE, Jiwrajka N, Driscoll AM, Shallberg LA, Cunningham-Rundles C, Barmettler S, Farmer J, Verbsky J, Routes J, Beiting DP, Romberg N, May MJ, Anguera MC) Sci Immunol 2024 Oct 04;9(100):eado0398       11 Citations
1Impaired B-cell function in ERCC2 deficiency. (Rossmanith R, Sauerwein K, Geier CB, Leiss-Piller A, Stemberger RF, Sharapova S, Gruber RW, Bergler H, Verbsky JW, Csomos K, Walter JE, Wolf HM) Front Immunol 2024;15:1423141       5 Citations
1Consensus recommendations on the management of toxicity associated with CD3×CD20 bispecific antibody therapy. (Crombie JL, Graff T, Falchi L, Karimi YH, Bannerji R, Nastoupil L, Thieblemont C, Ursu R, Bartlett N, Nachar V, Weiss J, Osterson J, Patel K, Brody J, Abramson JS, Lunning M, Shah NN, Ayed A, Kamdar M, Parsons B, Caimi P, Flinn I, Herrera A, Sharman J, McKenna M, Armand P, Kahl B, Smith S, Zelenetz A, Budde LE, Hutchings M, Phillips T, Dickinson M) Blood 2024 Apr 18;143(16):1565-1575       129 Citations
1Cationic micelle delivery of a multi-epitope vaccine candidate derived from tumor-associated antigens, causing regression in established CT26 colorectal tumors in mice. (Sabzehei F, Taromchi AH, Ramazani A, Nedaei K, Feizi A, Arsang-Jang S, Danafar H) J Biomed Mater Res A 2024 May;112(5):733-742       3 Citations
1Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases. (Sullivan KM, Jiang X, Guha P, Lausted C, Carter JA, Hsu C, Labadie KP, Kohli K, Kenerson HL, Daniel SK, Yan X, Meng C, Abbasi A, Chan M, Seo YD, Park JO, Crispe IN, Yeung RS, Kim TS, Gujral TS, Tian Q, Katz SC, Pillarisetty VG) Gut 2023 Feb;72(2):325-337       132 Citations
2Donor T-Cell Repertoire Profiling in Recipient Lymphoid and Parenchyma Organs Reveals GVHD Pathogenesis at Clonal Levels After Bone Marrow Transplantation in Mice. (Wu Y, Fu J, Wang H, Yu XZ) Front Immunol 2021;12:778996       6 Citations
1Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells. (Peng C, Huggins MA, Wanhainen KM, Knutson TP, Lu H, Georgiev H, Mittelsteadt KL, Jarjour NN, Wang H, Hogquist KA, Campbell DJ, Borges da Silva H, Jameson SC) Immunity 2022 Jan 11;55(1):98-114.e5       91 Citations
1The Role of microRNAs in NK Cell Development and Function. (Nanbakhsh A, Malarkannan S) Cells 2021 Aug 07;10(8)       15 Citations
2Implications of a 'Third Signal' in NK Cells. (Khalil M, Wang D, Hashemi E, Terhune SS, Malarkannan S) Cells 2021 Jul 31;10(8)       13 Citations
1T Cell-Intrinsic Interferon Regulatory Factor 1 Expression Suppresses Differentiation of CD4+ T Cell Populations That Support Chronic Gammaherpesvirus Infection. (Jondle CN, Johnson KE, Mboko WP, Tarakanova VL) J Virol 2021 Sep 27;95(20):e0072621       8 Citations
1Conserved Gammaherpesvirus Protein Kinase Counters the Antiviral Effects of Myeloid Cell-Specific STAT1 Expression To Promote the Establishment of Splenic B Cell Latency. (Sylvester PA, Jondle CN, Stoltz KP, Lanham J, Dittel BN, Tarakanova VL) J Virol 2021 Aug 10;95(17):e0085921       10 Citations
1Anisocytosis Is Associated With Reduced Bone Marrow Activity Evaluated by Positron Emission Tomography. (Janus SE, Al-Kindi SG, Hajjari J, Chami T, Avery A, Labbato D, Smith C, Sullivan C, Hileman CO, McComsey GA) Am J Cardiol 2021 Aug 01;152:179-180       3 Citations
1iNKT cells coordinate immune pathways to enable engraftment in nonconditioned hosts. (Hess NJ, S Bharadwaj N, Bobeck EA, McDougal CE, Ma S, Sauer JD, Hudson AW, Gumperz JE) Life Sci Alliance 2021 Jul;4(7)       13 Citations
1E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation. (Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W) Proc Natl Acad Sci U S A 2021 Apr 20;118(16)       31 Citations
2CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation. (Shapiro MR, Yeh WI, Longfield JR, Gallagher J, Infante CM, Wellford S, Posgai AL, Atkinson MA, Campbell-Thompson M, Lieberman SM, Serreze DV, Geurts AM, Chen YG, Brusko TM) Front Immunol 2020;11:2180       27 Citations
1RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity. (Ansa-Addo EA, Huang HC, Riesenberg B, Iamsawat S, Borucki D, Nelson MH, Nam JH, Chung D, Paulos CM, Liu B, Yu XZ, Philpott C, Howe PH, Li Z) Sci Adv 2020 May;6(22):eaaz3865       39 Citations
2Early T Cell Activation Metrics Predict Graft-versus-Host Disease in a Humanized Mouse Model of Hematopoietic Stem Cell Transplantation. (Hess NJ, Hudson AW, Hematti P, Gumperz JE) J Immunol 2020 Jul 01;205(1):272-281       20 Citations
1A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections. (Wu J, Hayes BW, Phoenix C, Macias GS, Miao Y, Choi HW, Hughes FM Jr, Todd Purves J, Lee Reinhardt R, Abraham SN) Nat Immunol 2020 Jun;21(6):671-683       58 Citations
1Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes. (Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin CM, Alontaga AY, McDaniel JM, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence HR, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha AM, Cleveland JL, Epling-Burnette PK) Blood 2020 Aug 13;136(7):857-870       18 Citations
1B Cell-Intrinsic Expression of Interferon Regulatory Factor 1 Supports Chronic Murine Gammaherpesvirus 68 Infection. (Jondle CN, Johnson KE, Uitenbroek AA, Sylvester PA, Nguyen C, Cui W, Tarakanova VL) J Virol 2020 Jun 16;94(13)       15 Citations
1The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137+ FOXP3+ Regulatory CD4 T Cells. (Foda BM, Ciecko AE, Serreze DV, Ridgway WM, Geurts AM, Chen YG) J Immunol 2020 Jun 01;204(11):2887-2899       16 Citations
1Gammaherpesviruses and B Cells: A Relationship That Lasts a Lifetime. (Johnson KE, Tarakanova VL) Viral Immunol 2020 May;33(4):316-326       21 Citations
1Vitamin C stabilizes CD8+ iTregs and enhances their therapeutic potential in controlling murine GVHD and leukemia relapse. (Iamsawat S, Tian L, Daenthanasanmak A, Wu Y, Nguyen HD, Bastian D, Yu XZ) Blood Adv 2019 Dec 23;3(24):4187-4201       21 Citations
1Soluble CD137 Ameliorates Acute Type 1 Diabetes by Inducing T Cell Anergy. (Itoh A, Ortiz L, Kachapati K, Wu Y, Adams D, Bednar K, Mukherjee S, Chougnet C, Mittler RS, Chen YG, Dolan L, Ridgway WM) Front Immunol 2019;10:2566       24 Citations
1Induction of activated T follicular helper cells is critical for anti-FVIII inhibitor development in hemophilia A mice. (Jing W, Chen J, Cai Y, Chen Y, Schroeder JA, Johnson BD, Cui W, Shi Q) Blood Adv 2019 Oct 22;3(20):3099-3110       34 Citations
1B Cell-Intrinsic SHP1 Expression Promotes the Gammaherpesvirus-Driven Germinal Center Response and the Establishment of Chronic Infection. (Johnson KE, Lange PT, Jondle CN, Volberding PJ, Lorenz UM, Cui W, Dittel BN, Tarakanova VL) J Virol 2019 Dec 12;94(1)       12 Citations
1Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8+ T-Cell Activation. (Wang Z, Vaughan TY, Zhu W, Chen Y, Fu G, Medrzycki M, Nishio H, Bunting ST, Hankey-Giblin PA, Nusrat A, Parkos CA, Wang D, Wen R, Bunting KD) Front Immunol 2019;10:486       16 Citations
1Inflammatory Cytokine Networks in Gastrointestinal Tract Graft vs. Host Disease. (Piper C, Drobyski WR) Front Immunol 2019;10:163       37 Citations
1Conserved Gammaherpesvirus Protein Kinase Selectively Promotes Irrelevant B Cell Responses. (Darrah EJ, Jondle CN, Johnson KE, Xin G, Lange PT, Cui W, Olteanu H, Tarakanova VL) J Virol 2019 Apr 15;93(8)       20 Citations
1Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. (Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, Atkinson C, Ogretmen B, Tomlinson S, Yu XZ) JCI Insight 2018 Dec 20;3(24)       35 Citations
1Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice. (Daenthanasanmak A, Iamsawat S, Chakraborty P, Nguyen HD, Bastian D, Liu C, Mehrotra S, Yu XZ) Blood 2019 Jan 17;133(3):266-279       73 Citations
4Frontline Science: PECAM-1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells. (Newman DK, Fu G, McOlash L, Schauder D, Newman PJ, Cui W, Rao S, Johnson BD, Gershan JA, Riese MJ) J Leukoc Biol 2018 Nov;104(5):883-893       20 Citations
1B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation. (Miggelbrink AM, Logan BR, Buckley RH, Parrott RE, Dvorak CC, Kapoor N, Abdel-Azim H, Prockop SE, Shyr D, Decaluwe H, Hanson IC, Gillio A, Dávila Saldaña BJ, Eibel H, Hopkins G, Walter JE, Whangbo JS, Kohn DB, Puck JM, Cowan MJ, Griffith LM, Haddad E, O'Reilly RJ, Notarangelo LD, Pai SY) Blood 2018 Jun 28;131(26):2967-2977       40 Citations
1A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. (Chang YL, Rossetti M, Vlamakis H, Casero D, Sunga G, Harre N, Miller S, Humphries R, Stappenbeck T, Simpson KW, Sartor RB, Wu G, Lewis J, Bushman F, McGovern DPB, Salzman N, Borneman J, Xavier R, Huttenhower C, Braun J) Mucosal Immunol 2019 Mar;12(2):457-467       55 Citations
1MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice. (Wu Y, Schutt S, Paz K, Zhang M, Flynn RP, Bastian D, Sofi MH, Nguyen H, Dai M, Liu C, Chang YJ, Blazar BR, Yu XZ) Blood 2018 Apr 26;131(17):1974-1986       52 Citations
1Inhibition of the IRE-1α/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice. (Schutt SD, Wu Y, Tang CH, Bastian D, Nguyen H, Sofi MH, Zhang M, Liu C, Helke K, Wilson C, Schnapp LM, Del Valle JR, Hu CC, Yu XZ) Blood Adv 2018 Feb 27;2(4):414-427       24 Citations
1T-Cell Metabolism in Hematopoietic Cell Transplantation. (Nguyen HD, Kuril S, Bastian D, Yu XZ) Front Immunol 2018;9:176       30 Citations
1Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiation. (Betts BC, Bastian D, Iamsawat S, Nguyen H, Heinrichs JL, Wu Y, Daenthanasanmak A, Veerapathran A, O'Mahony A, Walton K, Reff J, Horna P, Sagatys EM, Lee MC, Singer J, Chang YJ, Liu C, Pidala J, Anasetti C, Yu XZ) Proc Natl Acad Sci U S A 2018 Feb 13;115(7):1582-1587       66 Citations
1The structure, expression, and multifaceted role of immune-checkpoint protein VISTA as a critical regulator of anti-tumor immunity, autoimmunity, and inflammation. (Xu W, Hiếu T, Malarkannan S, Wang L) Cell Mol Immunol 2018 May;15(5):438-446       119 Citations
1Blockade of BAFF Receptor BR3 on T Cells Enhances Their Activation and Cytotoxicity. (Bloom DD, Reshetylo S, Nytes C, Goodsett CT, Hematti P) J Immunother 2018 Jun;41(5):213-223       10 Citations
1Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated. (Chen Y, Luo X, Schroeder JA, Chen J, Baumgartner CK, Hu J, Shi Q) J Thromb Haemost 2017 Oct;15(10):1994-2004       33 Citations
2Versican-Derived Matrikines Regulate Batf3-Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer. (Hope C, Emmerich PB, Papadas A, Pagenkopf A, Matkowskyj KA, Van De Hey DR, Payne SN, Clipson L, Callander NS, Hematti P, Miyamoto S, Johnson MG, Deming DA, Asimakopoulos F) J Immunol 2017 Sep 01;199(5):1933-1941       100 Citations
1Adoptive cell therapy using PD-1+ myeloma-reactive T cells eliminates established myeloma in mice. (Jing W, Gershan JA, Blitzer GC, Palen K, Weber J, McOlash L, Riese M, Johnson BD) J Immunother Cancer 2017;5:51       34 Citations
1T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model. (Woods DM, Woan KV, Cheng F, Sodré AL, Wang D, Wu Y, Wang Z, Chen J, Powers J, Pinilla-Ibarz J, Yu Y, Zhang Y, Wu X, Zheng X, Weber J, Hancock WW, Seto E, Villagra A, Yu XZ, Sotomayor EM) Blood 2017 Jul 13;130(2):146-155       69 Citations
1LIGHT Elevation Enhances Immune Eradication of Colon Cancer Metastases. (Qiao G, Qin J, Kunda N, Calata JF, Mahmud DL, Gann P, Fu YX, Rosenberg SA, Prabhakar BS, Maker AV) Cancer Res 2017 Apr 15;77(8):1880-1891       42 Citations
1Interferon-γ Limits Diabetogenic CD8+ T-Cell Effector Responses in Type 1 Diabetes. (Driver JP, Racine JJ, Ye C, Lamont DJ, Newby BN, Leeth CM, Chapman HD, Brusko TM, Chen YG, Mathews CE, Serreze DV) Diabetes 2017 Mar;66(3):710-721       36 Citations
1T-cell programming in pancreatic adenocarcinoma: a review. (Seo YD, Pillarisetty VG) Cancer Gene Ther 2017 Mar;24(3):106-113       47 Citations
3Phospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell development. (Fu G, Yu M, Chen Y, Zheng Y, Zhu W, Newman DK, Wang D, Wen R) Eur J Immunol 2017 Jan;47(1):74-83       8 Citations
1Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus. (Sturgill ER, Malouli D, Hansen SG, Burwitz BJ, Seo S, Schneider CL, Womack JL, Verweij MC, Ventura AB, Bhusari A, Jeffries KM, Legasse AW, Axthelm MK, Hudson AW, Sacha JB, Picker LJ, Früh K) PLoS Pathog 2016 Aug;12(8):e1005868       35 Citations
1Editorial: Treg potency and the importance of being fit. (Jeschke JC, Williams CB) J Leukoc Biol 2016 Jul;100(1):1-3       1 Citation
2X-linked Hyper IgM Syndrome Presenting as Pulmonary Alveolar Proteinosis. (Gallagher J, Adams J, Hintermeyer M, Torgerson TR, Lopez-Guisa J, Ochs HD, Szabo S, Salib M, Verbsky J, Routes J) J Clin Immunol 2016 Aug;36(6):564-70       13 Citations
1Initial in vitro studies on tissues and cells from GTKO/CD46/NeuGcKO pigs. (Lee W, Hara H, Ezzelarab MB, Iwase H, Bottino R, Long C, Ramsoondar J, Ayares D, Cooper DK) Xenotransplantation 2016 Mar;23(2):137-50       48 Citations
1Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation. (Nguyen HD, Chatterjee S, Haarberg KM, Wu Y, Bastian D, Heinrichs J, Fu J, Daenthanasanmak A, Schutt S, Shrestha S, Liu C, Wang H, Chi H, Mehrotra S, Yu XZ) J Clin Invest 2016 Apr 01;126(4):1337-52       103 Citations
1T-bet Promotes Acute Graft-versus-Host Disease by Regulating Recipient Hematopoietic Cells in Mice. (Fu J, Wu Y, Nguyen H, Heinrichs J, Schutt S, Liu Y, Liu C, Jin J, Anasetti C, Yu XZ) J Immunol 2016 Apr 01;196(7):3168-79       7 Citations
1Microdomains, Inflammation, and Atherosclerosis. (Sorci-Thomas MG, Thomas MJ) Circ Res 2016 Feb 19;118(4):679-91       161 Citations
1Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms. (Tsao CC, Tsao PN, Chen YG, Chuang YH) PLoS One 2016;11(1):e0147710       18 Citations
1Kras Is Critical for B Cell Lymphopoiesis. (Chen Y, Zheng Y, You X, Yu M, Fu G, Su X, Zhou F, Zhu W, Wu Z, Zhang J, Wen R, Wang D) J Immunol 2016 Feb 15;196(4):1678-85       24 Citations
1CD4+ and CD8+ T Cell Activation in Children with Hepatitis C. (Sheiko MA, Golden-Mason L, Giugliano S, Hurtado CW, Mack CL, Narkewicz MR, Rosen HR) J Pediatr 2016 Mar;170:142-8.e1       12 Citations
1Inhibition of BTK and ITK with Ibrutinib Is Effective in the Prevention of Chronic Graft-versus-Host Disease in Mice. (Schutt SD, Fu J, Nguyen H, Bastian D, Heinrichs J, Wu Y, Liu C, McDonald DG, Pidala J, Yu XZ) PLoS One 2015;10(9):e0137641       84 Citations
1Gut Microbial Dysbiosis Due to Helicobacter Drives an Increase in Marginal Zone B Cells in the Absence of IL-10 Signaling in Macrophages. (Ray A, Basu S, Gharaibeh RZ, Cook LC, Kumar R, Lefkowitz EJ, Walker CR, Morrow CD, Franklin CL, Geiger TL, Salzman NH, Fodor A, Dittel BN) J Immunol 2015 Oct 01;195(7):3071-85       23 Citations
1Select host restriction factors are associated with HIV persistence during antiretroviral therapy. (Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK) AIDS 2015 Feb 20;29(4):411-20       46 Citations
1PTEN is a negative regulator of NK cell cytolytic function. (Briercheck EL, Trotta R, Chen L, Hartlage AS, Cole JP, Cole TD, Mao C, Banerjee PP, Hsu HT, Mace EM, Ciarlariello D, Mundy-Bosse BL, Garcia-Cao I, Scoville SD, Yu L, Pilarski R, Carson WE 3rd, Leone G, Pandolfi PP, Yu J, Orange JS, Caligiuri MA) J Immunol 2015 Feb 15;194(4):1832-40       40 Citations
1A reproducible immunopotency assay to measure mesenchymal stromal cell-mediated T-cell suppression. (Bloom DD, Centanni JM, Bhatia N, Emler CA, Drier D, Leverson GE, McKenna DH Jr, Gee AP, Lindblad R, Hei DJ, Hematti P) Cytotherapy 2015 Feb;17(2):140-51       81 Citations
1T-bet is critical for the development of acute graft-versus-host disease through controlling T cell differentiation and function. (Fu J, Wang D, Yu Y, Heinrichs J, Wu Y, Schutt S, Kaosaard K, Liu C, Haarberg K, Bastian D, McDonald DG, Anasetti C, Yu XZ) J Immunol 2015 Jan 01;194(1):388-97       37 Citations
1CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. (Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG) PLoS One 2014;9(10):e110731       90 Citations
2Upholding the T cell immune-regulatory function of CD31 inhibits the formation of T/B immunological synapses in vitro and attenuates the development of experimental autoimmune arthritis in vivo. (Clement M, Fornasa G, Loyau S, Morvan M, Andreata F, Guedj K, Khallou-Laschet J, Larghi P, Le Roux D, Bismuth G, Chiocchia G, Hivroz C, Newman DK, Nicoletti A, Caligiuri G) J Autoimmun 2015 Jan;56:23-33       20 Citations
1Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. (Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Kaffenberger B, Yang C, Towns WH, Lehman A, Johnson AJ, Muthusamy N, Devine SM, Jaglowski S, Serody JS, Murphy WJ, Munn DH, Luznik L, Hill GR, Wong HK, MacDonald KK, Maillard I, Koreth J, Elias L, Cutler C, Soiffer RJ, Antin JH, Ritz J, Panoskaltsis-Mortari A, Byrd JC, Blazar BR) J Clin Invest 2014 Nov;124(11):4867-76       173 Citations
1Murine splenic CD4⁺ T cells, induced by innate immune cell interactions and secreted factors, develop antileukemia cytotoxicity. (Nelles ME, Moreau JM, Furlonger CL, Berger A, Medin JA, Paige CJ) Cancer Immunol Res 2014 Nov;2(11):1113-24       11 Citations
1Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease. (Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG) AIDS 2014 Jul 31;28(12):1749-58       105 Citations
1STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity. (Betts BC, Veerapathran A, Pidala J, Yu XZ, Anasetti C) J Leukoc Biol 2014 Feb;95(2):205-13       30 Citations
1Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice. (Haarberg KM, Li J, Heinrichs J, Wang D, Liu C, Bronk CC, Kaosaard K, Owyang AM, Holland S, Masuda E, Tso K, Blazar BR, Anasetti C, Beg AA, Yu XZ) Blood 2013 Oct 03;122(14):2500-11       35 Citations
1Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes. (Dubovsky JA, Beckwith KA, Natarajan G, Woyach JA, Jaglowski S, Zhong Y, Hessler JD, Liu TM, Chang BY, Larkin KM, Stefanovski MR, Chappell DL, Frissora FW, Smith LL, Smucker KA, Flynn JM, Jones JA, Andritsos LA, Maddocks K, Lehman AM, Furman R, Sharman J, Mishra A, Caligiuri MA, Satoskar AR, Buggy JJ, Muthusamy N, Johnson AJ, Byrd JC) Blood 2013 Oct 10;122(15):2539-49       739 Citations
1Expression of CD1c enhances human invariant NKT cell activation by α-GalCer. (Fox LM, Miksanek J, May NA, Scharf L, Lockridge JL, Veerapen N, Besra GS, Adams EJ, Hudson AW, Gumperz JE) Cancer Immun 2013;13:9       12 Citations
1Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice. (Li J, Heinrichs J, Leconte J, Haarberg K, Semple K, Liu C, Gigoux M, Kornete M, Piccirillo CA, Suh WK, Yu XZ) J Immunol 2013 Jul 01;191(1):200-7       21 Citations
1c-Rel is an essential transcription factor for the development of acute graft-versus-host disease in mice. (Yu Y, Wang D, Kaosaard K, Liu C, Fu J, Haarberg K, Anasetti C, Beg AA, Yu XZ) Eur J Immunol 2013 Sep;43(9):2327-37       19 Citations
1Premature cell senescence and T cell receptor-independent activation of CD8+ T cells in juvenile idiopathic arthritis. (Dvergsten JA, Mueller RG, Griffin P, Abedin S, Pishko A, Michel JJ, Rosenkranz ME, Reed AM, Kietz DA, Vallejo AN) Arthritis Rheum 2013 Aug;65(8):2201-10       33 Citations
1Reply to "testing for herpesvirus infection is essential in children with chromosomal-instability syndromes". (Kulinski JM, Tarakanova VL) J Virol 2013 Mar;87(6):3618       2 Citations
1Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms. (Yu Y, Cho HI, Wang D, Kaosaard K, Anasetti C, Celis E, Yu XZ) J Immunol 2013 Feb 15;190(4):1873-81       60 Citations
1High density lipoprotein biogenesis, cholesterol efflux, and immune cell function. (Sorci-Thomas MG, Thomas MJ) Arterioscler Thromb Vasc Biol 2012 Nov;32(11):2561-5       98 Citations
1The transition state analog inhibitor of Purine Nucleoside Phosphorylase (PNP) Immucillin-H arrests bone loss in rat periodontal disease models. (Deves C, de Assunção TM, Ducati RG, Campos MM, Basso LA, Santos DS, Batista EL Jr) Bone 2013 Jan;52(1):167-75       6 Citations
1Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection. (Kulinski JM, Leonardo SM, Mounce BC, Malherbe L, Gauld SB, Tarakanova VL) J Virol 2012 Dec;86(23):12826-37       33 Citations
1GB virus C infection is associated with a reduced rate of reactivation of latent HIV and protection against activation-induced T-cell death. (Rydze RT, Bhattarai N, Stapleton JT) Antivir Ther 2012;17(7):1271-9       34 Citations
1GB virus C viremia is associated with higher levels of double-negative T cells and lower T-cell activation in HIV-infected individuals receiving antiretroviral therapy. (Bhattarai N, Rydze RT, Chivero ET, Stapleton JT) J Infect Dis 2012 Nov;206(9):1469-72       22 Citations
1Expansion of follicular helper T cells in the absence of Treg cells: implications for loss of B-cell anergy. (Leonardo SM, De Santis JL, Gehrand A, Malherbe LP, Gauld SB) Eur J Immunol 2012 Oct;42(10):2597-607       22 Citations
1LBH589 enhances T cell activation in vivo and accelerates graft-versus-host disease in mice. (Wang D, Iclozan C, Liu C, Xia C, Anasetti C, Yu XZ) Biol Blood Marrow Transplant 2012 Aug;18(8):1182-1190.e1       25 Citations
1Regulation of acute graft-versus-host disease by microRNA-155. (Ranganathan P, Heaphy CE, Costinean S, Stauffer N, Na C, Hamadani M, Santhanam R, Mao C, Taylor PA, Sandhu S, He G, Shana'ah A, Nuovo GJ, Lagana A, Cascione L, Obad S, Broom O, Kauppinen S, Byrd JC, Caligiuri M, Perrotti D, Hadley GA, Marcucci G, Devine SM, Blazar BR, Croce CM, Garzon R) Blood 2012 May 17;119(20):4786-97       131 Citations
1Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation. (Kwun J, Malarkannan S, Burlingham WJ, Knechtle SJ) J Immunol 2011 Oct 15;187(8):3997-4006       17 Citations
1Effect of Thuja occidentalis and its polysaccharide on cell-mediated immune responses and cytokine levels of metastatic tumor-bearing animals. (Sunila ES, Hamsa TP, Kuttan G) Pharm Biol 2011 Oct;49(10):1065-73       33 Citations
1Roles of CD28, CTLA4, and inducible costimulator in acute graft-versus-host disease in mice. (Li J, Semple K, Suh WK, Liu C, Chen F, Blazar BR, Yu XZ) Biol Blood Marrow Transplant 2011 Jul;17(7):962-9       45 Citations
1Targeting iNKT cells for the treatment of sickle cell disease. (Field JJ, Nathan DG, Linden J) Clin Immunol 2011 Aug;140(2):177-83       41 Citations
1Efficient and selective prevention of GVHD by antigen-specific induced Tregs via linked-suppression in mice. (Semple K, Yu Y, Wang D, Anasetti C, Yu XZ) Biol Blood Marrow Transplant 2011 Mar;17(3):309-18       44 Citations
1Adenoviral-transduced dendritic cells are susceptible to suppression by T regulatory cells and promote interleukin 17 production. (Wang AY, Crome SQ, Jenkins KM, Medin JA, Bramson JL, Levings MK) Cancer Immunol Immunother 2011 Mar;60(3):381-8       3 Citations
2Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes. (Duerr CU, Salzman NH, Dupont A, Szabo A, Normark BH, Normark S, Locksley RM, Mellroth P, Hornef MW) Mucosal Immunol 2011 May;4(3):325-34       28 Citations
1Functional dichotomy between NKG2D and CD28-mediated co-stimulation in human CD8+ T cells. (Rajasekaran K, Xiong V, Fong L, Gorski J, Malarkannan S) PLoS One 2010 Sep 09;5(9)       40 Citations
1Apolipoprotein A-I modulates regulatory T cells in autoimmune LDLr-/-, ApoA-I-/- mice. (Wilhelm AJ, Zabalawi M, Owen JS, Shah D, Grayson JM, Major AS, Bhat S, Gibbs DP Jr, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2010 Nov 12;285(46):36158-69       123 Citations
2TCR stimulation drives cleavage and shedding of the ITIM receptor CD31. (Fornasa G, Groyer E, Clement M, Dimitrov J, Compain C, Gaston AT, Varthaman A, Khallou-Laschet J, Newman DK, Graff-Dubois S, Nicoletti A, Caligiuri G) J Immunol 2010 May 15;184(10):5485-92       59 Citations
2Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance. (Fu G, Chen Y, Yu M, Podd A, Schuman J, He Y, Di L, Yassai M, Haribhai D, North PE, Gorski J, Williams CB, Wang D, Wen R) J Exp Med 2010 Feb 15;207(2):309-18       118 Citations
1Acid sphingomyelinase deficiency does not protect from graft-versus-host disease in transplant recipients with Niemann-Pick disease. (Tolar J, Eapen M, Orchard PJ, Blazar BR) Blood 2010 Jan 14;115(2):434-5       3 Citations
1Lack of evidence for a pathogenic role of T-lymphocytes in an animal model for Charcot-Marie-Tooth disease 1A. (Kohl B, Groh J, Wessig C, Wiendl H, Kroner A, Martini R) Neurobiol Dis 2010 Apr;38(1):78-84       14 Citations
1Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques. (Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M Jr, O'Connor D, Lifson JD, Roederer M, Ohlen C) J Immunol 2010 Jan 01;184(1):303-14       33 Citations
1PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice. (Valenzuela JO, Iclozan C, Hossain MS, Prlic M, Hopewell E, Bronk CC, Wang J, Celis E, Engelman RW, Blazar BR, Bevan MJ, Waller EK, Yu XZ, Beg AA) J Clin Invest 2009 Dec;119(12):3774-86       70 Citations
1Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette. (Driver JP, Scheuplein F, Chen YG, Grier AE, Wilson SB, Serreze DV) Diabetes 2010 Feb;59(2):423-32       26 Citations
1A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes. (Scheuplein F, Rissiek B, Driver JP, Chen YG, Koch-Nolte F, Serreze DV) J Autoimmun 2010 Mar;34(2):145-54       29 Citations
1Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death. (Yu Y, Iclozan C, Yamazaki T, Yang X, Anasetti C, Dong C, Yu XZ) Blood 2009 Jul 30;114(5):1026-8       34 Citations
1Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity. (Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Chan L, Oka K, Thomas MJ, Sorci-Thomas MG) Arterioscler Thromb Vasc Biol 2009 Jun;29(6):843-9       112 Citations
1Murine NKG2D ligands: "double, double toil and trouble". (Samarakoon A, Chu H, Malarkannan S) Mol Immunol 2009 Mar;46(6):1011-9       40 Citations
1The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy. (Kroner A, Schwab N, Ip CW, Sommer C, Wessig C, Wiendl H, Martini R) Neurobiol Dis 2009 Jan;33(1):96-103       12 Citations
1Induction of a VLA-2 (CD49b)-expressing effector T cell population by a cell-based neuroblastoma vaccine expressing CD137L. (Yan X, Johnson BD, Orentas RJ) J Immunol 2008 Oct 01;181(7):4621-31       16 Citations
1TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. (Wang H, Peters T, Sindrilaru A, Kess D, Oreshkova T, Yu XZ, Seier AM, Schreiber H, Wlaschek M, Blakytny R, Röhrbein J, Schulz G, Weiss JM, Scharffetter-Kochanek K) J Clin Invest 2008 Jul;118(7):2629-39       61 Citations
1B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. (Ortler S, Leder C, Mittelbronn M, Zozulya AL, Knolle PA, Chen L, Kroner A, Wiendl H) Eur J Immunol 2008 Jun;38(6):1734-44       72 Citations
1Primary naive and interleukin-2-activated natural killer cells do not support efficient ectromelia virus replication. (Parker AK, Yokoyama WM, Corbett JA, Chen N, Buller RML) J Gen Virol 2008 Mar;89(Pt 3):751-759       6 Citations
1Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effects. (Liang Y, Liu C, Djeu JY, Zhong B, Peters T, Scharffetter-Kochanek K, Anasetti C, Yu XZ) Blood 2008 Jan 15;111(2):954-62       44 Citations
1Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice. (Leder C, Schwab N, Ip CW, Kroner A, Nave KA, Dornmair K, Martini R, Wiendl H) Mol Cell Neurosci 2007 Nov;36(3):416-24       16 Citations
1Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice. (Chen YG, Driver JP, Silveira PA, Serreze DV) Immunogenetics 2007 Sep;59(9):705-12       23 Citations
1Cellular immune response to an engineered cell-based tumor vaccine at the vaccination site. (Zhou Q, Johnson BD, Orentas RJ) Cell Immunol 2007 Feb;245(2):91-102       6 Citations
1Regulatory T cells dynamically control the primary immune response to foreign antigen. (Haribhai D, Lin W, Relland LM, Truong N, Williams CB, Chatila TA) J Immunol 2007 Mar 01;178(5):2961-72       203 Citations
1Regulatory T cell development in the absence of functional Foxp3. (Lin W, Haribhai D, Relland LM, Truong N, Carlson MR, Williams CB, Chatila TA) Nat Immunol 2007 Apr;8(4):359-68       427 Citations
1Frequency analysis of HLA-B7-restricted Epstein-Barr virus-specific cytotoxic T lymphocytes in patients with multiple sclerosis and healthy controls. (Gronen F, Ruprecht K, Weissbrich B, Klinker E, Kroner A, Hofstetter HH, Rieckmann P) J Neuroimmunol 2006 Nov;180(1-2):185-92       40 Citations
1Estradiol protects against ethanol-induced bone loss by inhibiting up-regulation of receptor activator of nuclear factor-kappaB ligand in osteoblasts. (Chen JR, Haley RL, Hidestrand M, Shankar K, Liu X, Lumpkin CK, Simpson PM, Badger TM, Ronis MJ) J Pharmacol Exp Ther 2006 Dec;319(3):1182-90       58 Citations
1CD38 is required for the peripheral survival of immunotolerogenic CD4+ invariant NK T cells in nonobese diabetic mice. (Chen YG, Chen J, Osborne MA, Chapman HD, Besra GS, Porcelli SA, Leiter EH, Wilson SB, Serreze DV) J Immunol 2006 Sep 01;177(5):2939-47       27 Citations
1T-cell tolerance or function is determined by combinatorial costimulatory signals. (Nurieva R, Thomas S, Nguyen T, Martin-Orozco N, Wang Y, Kaja MK, Yu XZ, Dong C) EMBO J 2006 Jun 07;25(11):2623-33       220 Citations
1Tumor-derived macrophage migration inhibitory factor (MIF) inhibits T lymphocyte activation. (Yan X, Orentas RJ, Johnson BD) Cytokine 2006 Feb 21;33(4):188-98       55 Citations
1Lack of susceptibility of cells from patients with Fabry disease to productive infection with R5 human immunodeficiency virus. (Lund N, Branch DR, Sakac D, Lingwood CA, Siatskas C, Robinson CJ, Brady RO, Medin JA) AIDS 2005 Sep 23;19(14):1543-6       32 Citations
1T-cell stimulation and regulation: with complements from CD46. (Kemper C, Verbsky JW, Price JD, Atkinson JP) Immunol Res 2005;32(1-3):31-43       46 Citations
1Autoantibodies to vascular smooth muscle are pathogenic for vasculitis. (Baiu DC, Barger B, Sandor M, Fabry Z, Hart MN) Am J Pathol 2005 Jun;166(6):1851-60       11 Citations
1A PD-1 polymorphism is associated with disease progression in multiple sclerosis. (Kroner A, Mehling M, Hemmer B, Rieckmann P, Toyka KV, Mäurer M, Wiendl H) Ann Neurol 2005 Jul;58(1):50-7       230 Citations
1Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes. (Chen YG, Choisy-Rossi CM, Holl TM, Chapman HD, Besra GS, Porcelli SA, Shaffer DJ, Roopenian D, Wilson SB, Serreze DV) J Immunol 2005 Feb 01;174(3):1196-204       133 Citations
1Functional reprogramming of the primary immune response by T cell receptor antagonism. (Haribhai D, Edwards B, Williams ML, Williams CB) J Exp Med 2004 Dec 06;200(11):1371-82       10 Citations
1Human T regulatory cells can use the perforin pathway to cause autologous target cell death. (Grossman WJ, Verbsky JW, Barchet W, Colonna M, Atkinson JP, Ley TJ) Immunity 2004 Oct;21(4):589-601       874 Citations
1Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture. (Stunz LL, Busch LK, Munroe ME, Sigmund CD, Tygrett LT, Waldschmidt TJ, Bishop GA) Immunity 2004 Aug;21(2):255-66       56 Citations
1Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. (Grossman WJ, Verbsky JW, Tollefsen BL, Kemper C, Atkinson JP, Ley TJ) Blood 2004 Nov 01;104(9):2840-8       443 Citations
2The T cell activation marker CD150 can be used to identify alloantigen-activated CD4(+)25+ regulatory T cells. (Browning MB, Woodliff JE, Konkol MC, Pati NT, Ghosh S, Truitt RL, Johnson BD) Cell Immunol 2004 Feb;227(2):129-39       18 Citations
1Lck is required for activation-induced T cell death after TCR ligation with partial agonists. (Yu XZ, Levin SD, Madrenas J, Anasetti C) J Immunol 2004 Feb 01;172(3):1437-43       17 Citations
1Selective elimination of alloreactive donor T cells attenuates graft-versus-host disease and enhances T-cell reconstitution. (Gendelman M, Yassai M, Tivol E, Krueger A, Gorski J, Drobyski WR) Biol Blood Marrow Transplant 2003 Dec;9(12):742-52       12 Citations
1Rapamycin antagonizes cyclosporin A- and tacrolimus (FK506)-mediated augmentation of linker for activation of T cell expression in T cells. (Cho CS, Chang Z, Elkahwaji J, Scheunemann TL, Manthei ER, Colburn M, Knechtle SJ, Hamawy MM) Int Immunol 2003 Nov;15(11):1369-78       11 Citations
1The immunology of psoriasis and biologic immunotherapy. (Mehlis SL, Gordon KB) J Am Acad Dermatol 2003 Aug;49(2 Suppl):S44-50       115 Citations
1Identification of T-cell epitopes in clotting factor IX and lack of tolerance in inbred mice. (Greenwood R, Wang B, Midkiff K, White GC 2nd, Lin HF, Frelinger JA) J Thromb Haemost 2003 Jan;1(1):95-102       16 Citations
1Role of the passive apoptotic pathway in graft-versus-host disease. (Drobyski WR, Komorowski R, Logan B, Gendelman M) J Immunol 2002 Aug 01;169(3):1626-33       15 Citations
1Chronic myelogenous leukemia in T cell lymphoid blastic phase achieving durable complete cytogenetic and molecular remission with imatinib mesylate (STI571; Gleevec) therapy. (Atallah E, Talpaz M, O'brien S, Rios MB, Guo JQ, Arlinghaus R, Fernandes-Reese S, Kantarjian H) Cancer 2002 Jun 01;94(11):2996-9       19 Citations
1Biologic therapy for psoriasis: the new therapeutic frontier. (Singri P, West DP, Gordon KB) Arch Dermatol 2002 May;138(5):657-63       107 Citations
1Differential abilities of central nervous system resident endothelial cells and astrocytes to serve as inducible antigen-presenting cells. (Girvin AM, Gordon KB, Welsh CJ, Clipstone NA, Miller SD) Blood 2002 May 15;99(10):3692-701       49 Citations
1Certain immune markers are not good indicators of mild to moderate biotin deficiency in rats. (Helm RM, Mock NI, Simpson P, Mock DM) J Nutr 2001 Dec;131(12):3231-6       5 Citations
1T cell proliferation and cytokine secretion to T cell epitopes of Asp f 2 in ABPA patients. (Rathore VB, Johnson B, Fink JN, Kelly KJ, Greenberger PA, Kurup VP) Clin Immunol 2001 Aug;100(2):228-35       28 Citations
1Mycobacterium bovis strain bacillus Calmette-Guérin-induced liver granulomas contain a diverse TCR repertoire, but a monoclonal T cell population is sufficient for protective granuloma formation. (Hogan LH, Macvilay K, Barger B, Co D, Malkovska I, Fennelly G, Sandor M) J Immunol 2001 May 15;166(10):6367-75       33 Citations
1Anti-CD3 epsilon F(ab')2 prevents graft-versus-host disease by selectively depleting donor T cells activated by recipient alloantigens. (Yu XZ, Bidwell SJ, Martin PJ, Anasetti C) J Immunol 2001 May 01;166(9):5835-9       33 Citations
1Quantitative analysis of the immune response to mouse non-MHC transplantation antigens in vivo: the H60 histocompatibility antigen dominates over all others. (Choi EY, Yoshimura Y, Christianson GJ, Sproule TJ, Malarkannan S, Shastri N, Joyce S, Roopenian DC) J Immunol 2001 Apr 01;166(7):4370-9       71 Citations
1Hemophilia factor VIII therapy. Immunological tolerance. A clinical perspective. (White GC 2nd, Greenwood R, Escobar M, Frelinger JA) Haematologica 2000 Oct;85(10 Suppl):113-6       7 Citations
1Characterization of high-risk HIV-1 seronegative hemophiliacs. (Salkowitz JR, Purvis SF, Meyerson H, Zimmerman P, O'Brien TR, Aledort L, Eyster ME, Hilgartner M, Kessler C, Konkle BA, White GC 2nd, Goedert JJ, Lederman MM) Clin Immunol 2001 Feb;98(2):200-11       55 Citations
1Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells. (Carpenter PA, Pavlovic S, Tso JY, Press OW, Gooley T, Yu XZ, Anasetti C) J Immunol 2000 Dec 01;165(11):6205-13       95 Citations
1Generation of antigen-specific, lacZ-inducible T-cell hybrids. (Malarkannan S, Mendoza LM, Shastri N) Methods Mol Biol 2001;156:265-72       18 Citations
1Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens. (Malarkannan S, Horng T, Eden P, Gonzalez F, Shih P, Brouwenstijn N, Klinge H, Christianson G, Roopenian D, Shastri N) Immunity 2000 Sep;13(3):333-44       76 Citations
1Adoptively transferred gamma delta T cells indirectly regulate murine graft-versus-host reactivity following donor leukocyte infusion therapy in mice. (Drobyski WR, Vodanovic-Jankovic S, Klein J) J Immunol 2000 Aug 01;165(3):1634-40       40 Citations
1Ligand-specific selection of MHC class II-restricted thymocytes in fetal thymic organ culture. (Kersh GJ, Engle DL, Williams CB, Allen PM) J Immunol 2000 Jun 01;164(11):5675-82       10 Citations
1CD28-specific antibody prevents graft-versus-host disease in mice. (Yu XZ, Bidwell SJ, Martin PJ, Anasetti C) J Immunol 2000 May 01;164(9):4564-8       79 Citations
1Enhancement of susceptibility to Fas-mediated apoptosis of TH1 cells by nonmitogenic anti-CD3epsilon F(ab')2. (Yu XZ, Anasetti C) Transplantation 2000 Jan 15;69(1):104-12       16 Citations
1Purified and recombinant latex proteins stimulate peripheral blood lymphocytes of latex allergic patients. (Johnson BD, Kurup VP, Sussman GL, Arif SA, Kelly KJ, Beezhold DH, Fink JN) Int Arch Allergy Immunol 1999 Dec;120(4):270-9       22 Citations
2Role of immunoregulatory donor T cells in suppression of graft-versus-host disease following donor leukocyte infusion therapy. (Johnson BD, Becker EE, LaBelle JL, Truitt RL) J Immunol 1999 Dec 15;163(12):6479-87       63 Citations
2Photochemical treatment with S-59 psoralen and ultraviolet A light to control the fate of naive or primed T lymphocytes in vivo after allogeneic bone marrow transplantation. (Truitt RL, Johnson BD, Hanke C, Talib S, Hearst JE) J Immunol 1999 Nov 01;163(9):5145-56       48 Citations
1Graft-facilitating doses of ex vivo activated gammadelta T cells do not cause lethal murine graft-vs.-host disease. (Drobyski WR, Majewski D, Hanson G) Biol Blood Marrow Transplant 1999;5(4):222-30       66 Citations
1A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. (Newton-Nash DK, Newman PJ) J Immunol 1999 Jul 15;163(2):682-8       145 Citations
1Selective induction of protective MHC class I-restricted CTL in the intestinal lamina propria of rhesus monkeys by transient SIV infection of the colonic mucosa. (Murphey-Corb M, Wilson LA, Trichel AM, Roberts DE, Xu K, Ohkawa S, Woodson B, Bohm R, Blanchard J) J Immunol 1999 Jan 01;162(1):540-9       88 Citations
1In vivo antagonism of a T cell response by an endogenously expressed ligand. (Basu D, Williams CB, Allen PM) Proc Natl Acad Sci U S A 1998 Nov 24;95(24):14332-6       38 Citations
2Sca1(+)/Mac1(+) nitric oxide-producing cells in the spleens of recipients early following bone marrow transplant suppress T cell responses in vitro. (Johnson BD, Hanke CA, Becker EE, Truitt RL) Cell Immunol 1998 Nov 01;189(2):149-59       12 Citations
1Ex vivo anti-CD3 antibody-activated donor T cells have a reduced ability to cause lethal murine graft-versus-host disease but retain their ability to facilitate alloengraftment. (Drobyski WR, Majewski D, Ozker K, Hanson G) J Immunol 1998 Sep 01;161(5):2610-9       48 Citations
1Z-138: a new mature B-cell acute lymphoblastic leukemia cell line from a patient with transformed chronic lymphocytic leukemia. (Estrov Z, Talpaz M, Ku S, Harris D, Van Q, Beran M, Hirsch-Ginsberg C, Huh Y, Yee G, Kurzrock R) Leuk Res 1998 Apr;22(4):341-53       33 Citations
1In vivo expression of a TCR antagonist: T cells escape central tolerance but are antagonized in the periphery. (Williams CB, Vidal K, Donermeyer D, Peterson DA, White JM, Allen PM) J Immunol 1998 Jul 01;161(1):128-37       30 Citations
1Theiler's virus infection of genetically susceptible mice induces central nervous system-infiltrating CTLs with no apparent viral or major myelin antigenic specificity. (Lin X, Pease LR, Murray PD, Rodriguez M) J Immunol 1998 Jun 01;160(11):5661-8       34 Citations
1Presentation of proteolipid protein epitopes and B7-1-dependent activation of encephalitogenic T cells by IFN-gamma-activated SJL/J astrocytes. (Tan L, Gordon KB, Mueller JP, Matis LA, Miller SD) J Immunol 1998 May 01;160(9):4271-9       108 Citations
2Glycosphingolipids as novel targets for T-cell suppression by the B subunit of recombinant heat-labile enterotoxin. (Truitt RL, Hanke C, Radke J, Mueller R, Barbieri JT) Infect Immun 1998 Apr;66(4):1299-308       35 Citations
1Elevated mutant frequencies in gene lacI in splenic lipopolysaccharide blasts after exposure to activated phagocytes in vitro. (Felix K, Lin S, Janz S) Eur J Immunol 1997 Sep;27(9):2160-4       5 Citations
1Donor gamma delta T lymphocytes promote allogeneic engraftment across the major histocompatibility barrier in mice. (Drobyski WR, Majewski D) Blood 1997 Feb 01;89(3):1100-9       41 Citations
1IFN-gamma-activated primary murine astrocytes express B7 costimulatory molecules and prime naive antigen-specific T cells. (Nikcevich KM, Gordon KB, Tan L, Hurst SD, Kroepfl JF, Gardinier M, Barrett TA, Miller SD) J Immunol 1997 Jan 15;158(2):614-21       143 Citations
1Induction of apoptosis by anti-CD3 epsilon F(ab')2 in antigen receptor transgenic murine T cells activated by specific peptide. (Yu XZ, Zhu L, Davis JE, Tso JY, Hansen JA, Anasetti C) J Immunol 1996 Oct 15;157(8):3420-9       20 Citations
2Modulation of in vitro and in vivo T-cell responses by transferrin-gallium and gallium nitrate. (Drobyski WR, Ul-Haq R, Majewski D, Chitambar CR) Blood 1996 Oct 15;88(8):3056-64       27 Citations
2Impaired immune function in a premature infant with zinc deficiency after total parenteral nutrition. (Fan PC, Teng RJ, Chou CC, Wu TJ, Tsou Yau KI, Hsieh KH) Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 1996;37(5):364-9    
1Endogenous altered peptide ligands can affect peripheral T cell responses. (Vidal K, Hsu BL, Williams CB, Allen PM) J Exp Med 1996 Apr 01;183(4):1311-21       61 Citations
1Immunoregulatory properties of ISG15, an interferon-induced cytokine. (D'Cunha J, Knight E Jr, Haas AL, Truitt RL, Borden EC) Proc Natl Acad Sci U S A 1996 Jan 09;93(1):211-5       347 Citations
1Silicone-induced T cell proliferation in mice. (McDonald AH, Weir K, Sanger JR) Curr Top Microbiol Immunol 1996;210:189-98       8 Citations
1A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells. (Malarkannan S, Afkarian M, Shastri N) J Exp Med 1995 Dec 01;182(6):1739-50       65 Citations
1Bacterial toxin superantigens stimulate all members of susceptible VB gene families. (Yassai M, Newton-Nash D, Gorski J) Ann N Y Acad Sci 1995 Jul 07;756:110-2       3 Citations
2Delayed infusion of immunocompetent donor cells after bone marrow transplantation breaks graft-host tolerance allows for persistent antileukemic reactivity without severe graft-versus-host disease. (Johnson BD, Truitt RL) Blood 1995 Jun 01;85(11):3302-12       136 Citations
2Characterization of human proliferative T cell responses to adenovirus. (Flomenberg P, Piaskowski V, Truitt RL, Casper JT) J Infect Dis 1995 May;171(5):1090-6       115 Citations
1Investigation of the role of the disulphide bond in the activity and structure of staphylococcal enterotoxin C1. (Hovde CJ, Marr JC, Hoffmann ML, Hackett SP, Chi YI, Crum KK, Stevens DL, Stauffacher CV, Bohach GA) Mol Microbiol 1994 Sep;13(5):897-909       89 Citations
1Predictions of T-cell receptor- and major histocompatibility complex-binding sites on staphylococcal enterotoxin C1. (Hoffmann ML, Jablonski LM, Crum KK, Hackett SP, Chi YI, Stauffacher CV, Stevens DL, Bohach GA) Infect Immun 1994 Aug;62(8):3396-407       65 Citations
1Efficacy of an influenza hemagglutinin-diphtheria toxoid conjugate vaccine in elderly nursing home subjects during an influenza outbreak. (Gravenstein S, Drinka P, Duthie EH, Miller BA, Brown CS, Hensley M, Circo R, Langer E, Ershler WB) J Am Geriatr Soc 1994 Mar;42(3):245-51       103 Citations
2Delayed cardiac allograft rejection due to combined cyclosporine and antioxidant therapy. (Slakey DP, Roza AM, Pieper GM, Johnson CP, Adams MB) Transplantation 1993 Dec;56(6):1305-9       35 Citations
1Differential effect of polymorphism at HLA-DR1 beta-chain positions 85 and 86 on binding and recognition of DR1-restricted antigenic peptides. (Newton-Nash DK, Eckels DD) J Immunol 1993 Mar 01;150(5):1813-21       69 Citations
3Immunological evaluation of pediatric cancer patients receiving recombinant interleukin-2 in a phase I trial. (Truitt RL, Piaskowski V, Kirchner P, McOlash L, Camitta BM, Casper JT) J Immunother (1991) 1992 May;11(4):274-85       19 Citations
1Effects of localized HLA class II beta chain polymorphism on binding of antigenic peptide and stimulation of T cells. (Newton-Nash DK, Eckels DD) Hum Immunol 1992 Mar;33(3):213-23       16 Citations
2Regulation of lymphokine-activated killer activity in T-replete and T-cell-depleted human bone marrow by interleukin 4. (Drobyski WR, LeFever AV, Truitt RL) Exp Hematol 1991 Oct;19(9):950-7       1 Citation
1The immunoregulatory effects of merocyanine 540 on in vitro human T- and B-lymphocyte functions. (Lum LG, Yamagami M, Giddings BR, Joshi I, Schober SL, Sensenbrenner LL, Sieber F) Blood 1991 Jun 15;77(12):2701-6       15 Citations
1Further characterization of PNK-E: a monoclonal antibody enhancing porcine natural killer cell activity. (Johnson BD, Wierda WG, Kim YB) Cell Immunol 1991 May;134(2):378-89       11 Citations
1A new method for delivering alkanes to mammalian cells: preparation and preliminary characterization of an inclusion complex between beta-cyclodextrin and pristane (2,6,10,14-tetramethylpentadecane). (Janz S, Shacter E) Toxicology 1991;69(3):301-15       27 Citations
3Preservation of lymphokine-activated killer activity following T cell depletion of human bone marrow. (Drobyski WR, Piaskowski V, Ash RC, Casper JT, Truitt RL) Transplantation 1990 Oct;50(4):625-32       17 Citations
1Immunotrophic methodology. (Nauss KM, Ross AC, Twining SS) Methods Enzymol 1990;190:259-73       3 Citations
1Modulation of lymphocyte proliferation and immunoglobulin production by transferrin-gallium. (Chitambar CR, Seigneuret MC, Matthaeus WG, Lum LG) Cancer Res 1989 Mar 01;49(5):1125-9       24 Citations
1Sleep deprivation in the rat: VII. Immune function. (Benca RM, Kushida CA, Everson CA, Kalski R, Bergmann BM, Rechtschaffen A) Sleep 1989 Feb;12(1):47-52       52 Citations
1The classical and alternate pathways of T cell activation are impaired in leprosy. (Muthukkaruppan V, Chakkalath HR, Malarkannan S) Immunol Lett 1988 Sep;19(1):55-8       4 Citations
1Cellular immunoregulation of acute pulmonary inflammation in strain 2 guinea pigs. (Pontzer CH, Newton-Nash DK, Garancis JC, Abramoff P) Reg Immunol 1988;1(2):119-27    
1Impaired immune function in obstructive jaundice. (Vane DW, Redlich P, Weber T, Leapman S, Siddiqui AR, Grosfeld JL) J Surg Res 1988 Sep;45(3):287-93       39 Citations
1Increase of protein synthesis by uridine supplement in lectin-stimulated peripheral blood lymphocytes and EB virus-transformed B cell line of hereditary orotic aciduria type I. (Yazaki M, Okajima K, Suchi M, Morishita H, Wada Y) Tohoku J Exp Med 1987 Nov;153(3):189-95       4 Citations
1Downregulation of L3T4+ cytotoxic T lymphocytes by interleukin-2. (Shih CC, Truitt RL) Science 1987 Oct 16;238(4825):344-7       11 Citations
1Prophylaxis of graft-vs-host disease by adoptive transfer of a class II antigen-specific murine T-cell clone. (Shih CC, Truitt RL) Prog Clin Biol Res 1987;244:439-47       5 Citations
1Manipulation of T-cell content in transplanted human bone marrow: effect on GVH and GVL reactions. (Truitt RL, Ash RC) Prog Clin Biol Res 1987;244:409-21       16 Citations
1Migration of cytotoxic effector cells. (LeFever AV, Truitt RL) Prog Clin Biol Res 1987;244:313-24       4 Citations
1Large scale separation of human bone marrow by counterflow centrifugation elutriation. (Noga SJ, Cremo CA, Duff SC, Schwartz CL, Melaragno A, Civin CI, Donnenberg AD) J Immunol Methods 1986 Sep 27;92(2):211-8       13 Citations
1Development of a simplified counterflow centrifugation elutriation procedure for depletion of lymphocytes from human bone marrow. (Noga SJ, Donnenberg AD, Schwartz CL, Strauss LC, Civin CI, Santos GW) Transplantation 1986 Feb;41(2):220-9       38 Citations
1Effect of dietary chronic cadmium exposure on cell-mediated immune response in rhesus monkeys (Macaca mulatta): role of calcium deficiency. (Chopra RK, Prasad R, Sharma N, Paliwal VK, Nath R) Arch Toxicol 1984 Dec;56(2):128-31       7 Citations
1Evaluation of lymphocyte subsets and suppressor cell function in long-term renal transplant recipients. (Redlich PN, Leapman SB, Marder P, Schmidtke J, Smith EJ, Fineberg N, Filo RS) Transplant Proc 1984 Dec;16(6):1555-7       1 Citation
1Vitamin E attenuates the effects of FMLP on rabbit circulating granulocytes. (Lafuze JE, Weisman SJ, Alpert LA, Baehner RL) Pediatr Res 1984 Jun;18(6):536-40       9 Citations
1Heated lymphocytes express HLA-DR antigens despite their inability to stimulate in MLC. (Brewer JA, Hank JA, Wendel T, Schmeling GJ, Blank JL, Morrissey LW, Robins HI, Sondel PM) Tissue Antigens 1983 Oct;22(4):246-56       26 Citations
1In vitro enhancement of peripheral blood mononuclear cell natural killer activity following short term incubation with fetal calf serum. (Lauer SJ, Finlan J, Borella LD, Piaskowski VD, Casper JT) J Clin Lab Immunol 1983 Oct;12(2):105-10       11 Citations
1Marijuana smoking and fungal sensitization. (Kagen SL, Kurup VP, Sohnle PG, Fink JN) J Allergy Clin Immunol 1983 Apr;71(4):389-93       97 Citations
1Kinetics of lymphokine production by lymphocytes from elderly humans. (Sohnle PG, Collins-Lech C, Huhta KE) Gerontology 1983;29(3):169-75       5 Citations
1Analysis of the lymphocyte transformation response to Pityrosporum orbiculare in patients with tinea versicolor. (Sohnle PG, Collins-Lech C) Clin Exp Immunol 1982 Sep;49(3):559-64       33 Citations
1Effects of reduced temperature on the components of human lymphocyte transformation responses to antigens. (Lettau LA, Sohnle PG) Infect Immun 1982 Jul;37(1):179-82       4 Citations
1Effect of age on generation of progeny from antigen-stimulated human lymphocytes. (Sohnle PG, Collins-Lech C, Huhta KE) Mech Ageing Dev 1982 Jan;18(1):53-8    
1Age-related effects on the number of human lymphocytes in culture initially responding to an antigenic stimulus. (Sohnle PG, Collins-Lech C, Huhta KE) Clin Exp Immunol 1982 Jan;47(1):138-46       16 Citations
1Lymphocyte transformation and the number of antigen-responsive cells in humans. (Sohnle PG, Collins-Lech C) J Immunol 1981 Aug;127(2):612-5       8 Citations
1A genetic defect of granulocyte oxidative metabolism in a man with disseminated aspergillosis. (Chusid MJ, Sohnle PG, Fink JN, Shea ML) J Lab Clin Med 1981 May;97(5):730-8       13 Citations
1Relative antigenicity of P. orbiculare and C. albicans. (Sohnle PG, Collins-Lech C) J Invest Dermatol 1980 Sep;75(3):279-83       19 Citations
1Direct stimulation of lymphokine production by cephalothin. (Larson SE, DaMert GJ, Collins-Lech C, Sohnle PG) J Infect Dis 1980 Aug;142(2):265-72       9 Citations
1Failure of lymphokine-producing lymphocytes from aged humans to undergo activation by recall antigens. (Sohnle PG, Larson SE, Collins-Lech C, Guansing AR) J Immunol 1980 May;124(5):2169-74       11 Citations
1Lymphocyte function in relapsed pulmonary blastomycosis. (Sohnle PG, Varkey B, Rose HD) J Allergy Clin Immunol 1980 May;65(5):376-80       3 Citations
1Genetic control of immune response to sperm whale myoglobin in mice. II. T lymphocyte proliferative response to the synthetic antigenic sites. (Okuda K, Twining SS, David CS, Atassi MZ) J Immunol 1979 Jul;123(1):182-8       111 Citations
1Differentiation of the effects of preincubation and indomethacin on lymphocyte transformation. (Sohnle PG, Collins-Lech C) Clin Immunol Immunopathol 1979 May;13(1):47-55       14 Citations
1Inhibition of lymphocyte transformation responses to phytohemagglutinin by normal human plasma. (Sohnle PG, Collins-Lech C) Cell Immunol 1979 Feb;42(2):428-36       9 Citations
1Effect of chloramphenicol on in vitro function of lymphocytes. (DaMert GJ, Sohnle PG) J Infect Dis 1979 Feb;139(2):220-4       18 Citations
1Heterogeneity in the membrane proteins of human lymphoid cell lines as seen in sodium dodecyl sulfate-polyacrylamide electrophoresis slab gels. (Rogan KM, Faldetta TJ, Boto W, Aiken JJ, DeMartino JL, Howe RC, Spiro RC, Humphreys RE) Cancer Res 1978 Nov;38(11 Pt 1):3604-10       12 Citations
1Genetic control of immune response to sperm whale myoglobin in mice. I. T lymphocyte proliferative response under H-2-linked Ir gene control. (Okuda K, Christadoss PR, Twining S, Atassi MZ, David CS) J Immunol 1978 Sep;121(3):866-8       67 Citations
1Cell-mediated immunity to Pityrosporum orbiculare in tinea versicolor. (Sohnle PG, Collins-Lech C) J Clin Invest 1978 Jul;62(1):45-53       59 Citations
1Interstitial nephritis due to phenytoin hypersensitivity. (Sheth KJ, Casper JT, Good TA) J Pediatr 1977 Sep;91(3):438-41       35 Citations
1Are Actinomyces viscosus antigens B cell mitogens? (Burckhardt JJ, Guggenheim B, Hefti A) J Immunol 1977 Apr;118(4):1460-5       30 Citations
1Study of possible mechanisms of basophil accumulation in experimental cutaneous candidiasis in guinea pigs. (Sohnle PG, Kirkpatrick CH) J Allergy Clin Immunol 1977 Feb;59(2):171-7       11 Citations