| 1 | Nascent preplatelets and B4GALT1 glycosylation contribute to 5-FU-induced bone marrow recovery. (Weich N, Rivadeneyra L, Roisman A, Rajaraman R, Steenackers A, Zheng S, Glabere S, Desai UR, Gu T, Falet H, Gaertner F, Hoffmeister KM) Blood Adv 2026 Jul 28;10(14):5045-5057 |
| 1 | Differentiating pathogenic from bystander autoantibodies in immune thrombocytopenia using intact glycoproteindeficient megakaryocytes. (Zhang N, Uzun G, Bakchoul T, Curtis BR, Newman PJ) Haematologica 2026 May 01;111(5):1725-1734 |
| 1 | Genetic engineering of megakaryocytes from blood progenitor cells using messenger RNA lipid nanoparticles. (Leung J, Primbetova A, Strong C, Hay BN, Hsu HH, Hagner A, Foster LJ, Devine D, Cullis PR, Zandstra PW, Kastrup CJ) J Thromb Haemost 2025 Jan;23(1):306-313 3 Citations |
| 1 | Elevating TPO production up a Notch. (Falet H, Hoffmeister KM) Blood 2024 Jun 27;143(26):2684-2686 1 Citation |
| 1 | Clinical impact of glycans in platelet and megakaryocyte biology. (Falet H, Rivadeneyra L, Hoffmeister KM) Blood 2022 Jun 02;139(22):3255-3263 15 Citations |
| 1 | Circulating platelet count and glycans. (Rivadeneyra L, Falet H, Hoffmeister KM) Curr Opin Hematol 2021 Nov 01;28(6):431-437 7 Citations |
| 2 | Immune cells surveil aberrantly sialylated O-glycans on megakaryocytes to regulate platelet count. (Lee-Sundlov MM, Burns RT, Kim TO, Grozovsky R, Giannini S, Rivadeneyra L, Zheng Y, Glabere SH, Kahr WHA, Abdi R, Despotovic JM, Wang D, Hoffmeister KM) Blood 2021 Dec 09;138(23):2408-2424 28 Citations |
| 2 | Platelet and myeloid cell phenotypes in a rat model of Fabry disease. (Kanack AJ, Aoki K, Tiemeyer M, Dahms NM) FASEB J 2021 Aug;35(8):e21818 4 Citations |
| 1 | Long-acting PGE2 and Lisinopril Mitigate H-ARS. (Saunders J, Niswander LM, McGrath KE, Koniski A, Catherman SC, Ture SK, Medhora M, Kingsley PD, Calvi LM, Williams JP, Morrell CN, Palis J) Radiat Res 2021 Sep 01;196(3):284-296 3 Citations |
| 1 | Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs. (Di Buduo CA, Giannini S, Abbonante V, Rosti V, Hoffmeister KM, Balduini A) Blood 2021 Apr 15;137(15):2085-2089 13 Citations |
| 2 | β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis. (Giannini S, Lee-Sundlov MM, Rivadeneyra L, Di Buduo CA, Burns R, Lau JT, Falet H, Balduini A, Hoffmeister KM) Nat Commun 2020 Jan 17;11(1):356 46 Citations |
| 1 | Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies. (Zhang N, Santoso S, Aster RH, Curtis BR, Newman PJ) Blood 2019 Nov 28;134(22):e1-e8 21 Citations |
| 2 | Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation. (Moroi AJ, Zwifelhofer NM, Riese MJ, Newman DK, Newman PJ) Blood Adv 2019 Apr 09;3(7):1154-1166 9 Citations |
| 1 | Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice. (Lorenz V, Ramsey H, Liu ZJ, Italiano J Jr, Hoffmeister K, Bihorel S, Mager D, Hu Z, Slayton WB, Kile BT, Sola-Visner M, Ferrer-Marin F) Thromb Haemost 2017 Dec;117(12):2322-2333 17 Citations |
| 1 | Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease. (Kahr WH, Pluthero FG, Elkadri A, Warner N, Drobac M, Chen CH, Lo RW, Li L, Li R, Li Q, Thoeni C, Pan J, Leung G, Lara-Corrales I, Murchie R, Cutz E, Laxer RM, Upton J, Roifman CM, Yeung RS, Brumell JH, Muise AM) Nat Commun 2017 Apr 03;8:14816 207 Citations |
| 1 | Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. (Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, Veeraraghavan N, Walter K, Chen L, Yanek L, Becker LC, Peloso GM, Wakabayashi A, Kals M, Metspalu A, Esko T, Fox K, Wallace R, Franceschini N, Matijevic N, Rice KM, Bartz TM, Lyytikäinen LP, Kähönen M, Lehtimäki T, Raitakari OT, Li-Gao R, Mook-Kanamori DO, Lettre G, van Duijn CM, Franco OH, Rich SS, Rivadeneira F, Hofman A, Uitterlinden AG, Wilson JG, Psaty BM, Soranzo N, Dehghan A, Boerwinkle E, Zhang X, Johnson AD, O'Donnell CJ, Johnsen JM, Reiner AP, Ganesh SK, Sankaran VG) Am J Hum Genet 2016 Aug 04;99(2):481-8 40 Citations |
| 1 | Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases. (Crescente M, Pluthero FG, Li L, Lo RW, Walsh TG, Schenk MP, Holbrook LM, Louriero S, Ali MS, Vaiyapuri S, Falet H, Jones IM, Poole AW, Kahr WH, Gibbins JM) Arterioscler Thromb Vasc Biol 2016 Jun;36(6):1164-73 57 Citations |
| 1 | Megakaryocyte- and megakaryocyte precursor-related gene therapies. (Wilcox DA) Blood 2016 Mar 10;127(10):1260-8 16 Citations |
| 2 | FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets. (Begonja AJ, Pluthero FG, Suphamungmee W, Giannini S, Christensen H, Leung R, Lo RW, Nakamura F, Lehman W, Plomann M, Hoffmeister KM, Kahr WH, Hartwig JH, Falet H) Blood 2015 Jul 02;126(1):80-8 52 Citations |
| 2 | Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice. (Bender M, Giannini S, Grozovsky R, Jönsson T, Christensen H, Pluthero FG, Ko A, Mullally A, Kahr WH, Hoffmeister KM, Falet H) Blood 2015 Feb 05;125(6):1014-24 45 Citations |
| 1 | Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect. (Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B) Nat Commun 2014 Sep 04;5:4746 88 Citations |
| 1 | Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan. (Liu ZJ, Hoffmeister KM, Hu Z, Mager DE, Ait-Oudhia S, Debrincat MA, Pleines I, Josefsson EC, Kile BT, Italiano J Jr, Ramsey H, Grozovsky R, Veng-Pedersen P, Chavda C, Sola-Visner M) Blood 2014 May 29;123(22):3381-9 67 Citations |
| 2 | High-level transgene expression in induced pluripotent stem cell-derived megakaryocytes: correction of Glanzmann thrombasthenia. (Sullivan SK, Mills JA, Koukouritaki SB, Vo KK, Lyde RB, Paluru P, Zhao G, Zhai L, Sullivan LM, Wang Y, Kishore S, Gharaibeh EZ, Lambert MP, Wilcox DA, French DL, Poncz M, Gadue P) Blood 2014 Jan 30;123(5):753-7 53 Citations |
| 2 | C560Rβ3 caused platelet integrin αII b β3 to bind fibrinogen continuously, but resulted in a severe bleeding syndrome and increased murine mortality. (Fang J, Nurden P, North P, Nurden AT, Du LM, Valentin N, Wilcox DA) J Thromb Haemost 2013 Jun;11(6):1163-71 19 Citations |
| 2 | Chronically inadequate sleep results in abnormal bone formation and abnormal bone marrow in rats. (Everson CA, Folley AE, Toth JM) Exp Biol Med (Maywood) 2012 Sep;237(9):1101-9 65 Citations |
| 1 | Death regulates platelet birth and life. (Hoffmeister KM) Blood 2012 Jun 14;119(24):5617-8 1 Citation |
| 2 | Contribution of platelet vs. endothelial VWF to platelet adhesion and hemostasis. (Kanaji S, Fahs SA, Shi Q, Haberichter SL, Montgomery RR) J Thromb Haemost 2012 Aug;10(8):1646-52 119 Citations |
| 1 | The origin and function of platelet glycosyltransferases. (Wandall HH, Rumjantseva V, Sørensen AL, Patel-Hett S, Josefsson EC, Bennett EP, Italiano JE Jr, Clausen H, Hartwig JH, Hoffmeister KM) Blood 2012 Jul 19;120(3):626-35 96 Citations |
| 2 | FlnA-null megakaryocytes prematurely release large and fragile platelets that circulate poorly. (Jurak Begonja A, Hoffmeister KM, Hartwig JH, Falet H) Blood 2011 Aug 25;118(8):2285-95 101 Citations |
| 1 | Cytoskeletal mechanics of proplatelet maturation and platelet release. (Thon JN, Montalvo A, Patel-Hett S, Devine MT, Richardson JL, Ehrlicher A, Larson MK, Hoffmeister K, Hartwig JH, Italiano JE Jr) J Cell Biol 2010 Nov 15;191(4):861-74 247 Citations |
| 2 | Platelets as delivery systems for disease treatments. (Shi Q, Montgomery RR) Adv Drug Deliv Rev 2010 Sep 30;62(12):1196-203 56 Citations |
| 2 | Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice. (Zhang G, Shi Q, Fahs SA, Kuether EL, Walsh CE, Montgomery RR) Blood 2010 Aug 26;116(8):1235-43 49 Citations |
| 2 | Type 2B von Willebrand disease associated with the release of platelet agglutinates from megakaryocytes in the bone marrow. (Slayton WB, Patel M, Sola-Visner M, Harris N, Rivers A, Montgomery RR, Friedman KD) J Pediatr Hematol Oncol 2008 Sep;30(9):708-11 7 Citations |
| 1 | The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. (Chen Z, Naveiras O, Balduini A, Mammoto A, Conti MA, Adelstein RS, Ingber D, Daley GQ, Shivdasani RA) Blood 2007 Jul 01;110(1):171-9 144 Citations |
| 1 | Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin. (Curtis BR, Kaliszewski J, Marques MB, Saif MW, Nabelle L, Blank J, McFarland JG, Aster RH) Am J Hematol 2006 Mar;81(3):193-8 104 Citations |
| 3 | Targeting platelet GPIbalpha transgene expression to human megakaryocytes and forming a complete complex with endogenous GPIbbeta and GPIX. (Shi Q, Wilcox DA, Morateck PA, Fahs SA, Kenny D, Montgomery RR) J Thromb Haemost 2004 Nov;2(11):1989-97 33 Citations |
| 1 | Enhanced effect of vascular endothelial growth factor, thrombopoietin peptide agonist, SCF, and Flt3-L on LTC-IC and reporter gene transduction from umbilical cord blood CD34+ cells. (Smith SL, Kiss J, Siatskas C, Medin JA, Moldwin RL) Transfusion 2004 Mar;44(3):438-49 2 Citations |
| 5 | Induction of megakaryocytes to synthesize and store a releasable pool of human factor VIII. (Wilcox DA, Shi Q, Nurden P, Haberichter SL, Rosenberg JB, Johnson BD, Nurden AT, White GC 2nd, Montgomery RR) J Thromb Haemost 2003 Dec;1(12):2477-89 56 Citations |
| 2 | Gene therapy for platelet disorders: studies with Glanzmann's thrombasthenia. (Wilcox DA, White GC 2nd) J Thromb Haemost 2003 Nov;1(11):2300-11 34 Citations |
| 1 | Decreased PMCA4b expression has no effect on calcium homeostasis in Meg-01 cells. (Wan TC, Dean WL) Platelets 2003 Aug;14(5):295-303 3 Citations |
| 3 | Expression of human factor VIII under control of the platelet-specific alphaIIb promoter in megakaryocytic cell line as well as storage together with VWF. (Shi Q, Wilcox DA, Fahs SA, Kroner PA, Montgomery RR) Mol Genet Metab 2003 May;79(1):25-33 46 Citations |
| 1 | Ex vivo expansion of megakaryocyte precursors from umbilical cord blood CD34 cells in a closed liquid culture system. (Shaw PH, Gilligan D, Wang XM, Thall PF, Corey SJ) Biol Blood Marrow Transplant 2003 Mar;9(3):151-6 20 Citations |
| 2 | Mechanisms and implications of platelet discoid shape. (Italiano JE Jr, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister KM, André P, Wagner DD, Shivdasani RA) Blood 2003 Jun 15;101(12):4789-96 148 Citations |
| 1 | Expansion of megakaryocyte precursors and stem cells from umbilical cord blood CD34+ cells in collagen and liquid culture media. (Shaw PH, Olszewski M, Kletzel M) J Hematother Stem Cell Res 2001 Jun;10(3):391-403 11 Citations |
| 1 | rhIL-11 for the prevention of dose-limiting chemotherapy-induced thrombocytopenia. (Kurzrock R) Oncology (Williston Park) 2000 Sep;14(9 Suppl 8):9-11 9 Citations |
| 2 | Megakaryocyte-targeted synthesis of the integrin beta(3)-subunit results in the phenotypic correction of Glanzmann thrombasthenia. (Wilcox DA, Olsen JC, Ishizawa L, Bray PF, French DL, Steeber DA, Bell WR, Griffith M, White GC 2nd) Blood 2000 Jun 15;95(12):3645-51 52 Citations |
| 1 | A phase I trial of recombinant human thrombopoietin in patients with delayed platelet recovery after hematopoietic stem cell transplantation. (Nash RA, Kurzrock R, DiPersio J, Vose J, Linker C, Maharaj D, Nademanee AP, Negrin R, Nimer S, Shulman H, Ashby M, Jones D, Appelbaum FR, Champlin R) Biol Blood Marrow Transplant 2000;6(1):25-34 83 Citations |
| 1 | Primary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta 3 signaling. (Shiraga M, Ritchie A, Aidoudi S, Baron V, Wilcox D, White G, Ybarrondo B, Murphy G, Leavitt A, Shattil S) J Cell Biol 1999 Dec 27;147(7):1419-30 78 Citations |
| 1 | Forced expression of the leukemia-associated gene EVI1 in ES cells: a model for myeloid leukemia with 3q26 rearrangements. (Sitailo S, Sood R, Barton K, Nucifora G) Leukemia 1999 Nov;13(11):1639-45 66 Citations |
| 2 | Integrin alphaIIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells. (Wilcox DA, Olsen JC, Ishizawa L, Griffith M, White GC 2nd) Proc Natl Acad Sci U S A 1999 Aug 17;96(17):9654-9 52 Citations |
| 1 | Thrombopoietin stimulates myelodysplastic syndrome granulocyte-macrophage and erythroid progenitor proliferation. (Ferrajoli A, Talpaz M, Kurzrock R, Harris D, Van Q, Estey EH, Estrov Z) Leuk Lymphoma 1998 Jul;30(3-4):279-92 8 Citations |
| 1 | Effect of ethanol on thrombopoiesis. (Levine RF, Spivak JL, Meagher RC, Sieber F) Br J Haematol 1986 Feb;62(2):345-54 66 Citations |
| 1 | Susceptibility to merocyanine 540-mediated photosensitization: a differentiation marker on murine hematopoietic progenitor cells. (Meagher RC, Sieber F, Spivak JL) J Cell Physiol 1983 Jul;116(1):118-24 54 Citations |
| 1 | The role of viral infections in aplastic anemia. (Camitta BM) Haematol Blood Transfus 1979;24:39-46 11 Citations |
