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1 | Mortalin depletion induces MEK/ERK-dependent and ANT/CypD-mediated death in vemurafenib-resistant B-RafV600E melanoma cells. (Wu PK, Hong SK, Park JI) Cancer Lett 2021 Apr 01;502:25-33 11 Citations |
2 | NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma. (Hu W, Liu Z, Salato V, North PE, Bischoff J, Kumar SN, Fang Z, Rajan S, Hussain MM, Miao QR) JCI Insight 2021 Feb 08;6(3) 9 Citations |
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1 | Cell Lineage-Based Stratification for Glioblastoma. (Wang Z, Sun D, Chen YJ, Xie X, Shi Y, Tabar V, Brennan CW, Bale TA, Jayewickreme CD, Laks DR, Alcantara Llaguno S, Parada LF) Cancer Cell 2020 Sep 14;38(3):366-379.e8 57 Citations |
1 | Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance. (Bi M, Zhang Z, Jiang YZ, Xue P, Wang H, Lai Z, Fu X, De Angelis C, Gong Y, Gao Z, Ruan J, Jin VX, Marangoni E, Montaudon E, Glass CK, Li W, Huang TH, Shao ZM, Schiff R, Chen L, Liu Z) Nat Cell Biol 2020 Jun;22(6):701-715 67 Citations |
1 | Gefitinib Inhibits Invasion and Metastasis of Osteosarcoma via Inhibition of Macrophage Receptor Interacting Serine-Threonine Kinase 2. (Maloney C, Kallis MP, Edelman M, Tzanavaris C, Lesser M, Soffer SZ, Symons M, Steinberg BM) Mol Cancer Ther 2020 Jun;19(6):1340-1350 13 Citations |
1 | Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability. (Wu PK, Hong SK, Starenki D, Oshima K, Shao H, Gestwicki JE, Tsai S, Park JI) Oncogene 2020 May;39(21):4257-4270 18 Citations |
3 | Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I. (Zhang Q, Cheng G, Pan J, Zielonka J, Xiong D, Myers CR, Feng L, Shin SS, Kim YH, Bui D, Hu M, Bennett B, Schmainda K, Wang Y, Kalyanaraman B, You M) Cell Commun Signal 2020 Apr 07;18(1):58 17 Citations |
7 | miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer. (Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2019 Dec 24;29(13):4389-4406.e10 52 Citations |
4 | Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse. (Urrutia G, Salmonson A, Toro-Zapata J, de Assuncao TM, Mathison A, Dusetti N, Iovanna J, Urrutia R, Lomberk G) Mol Cancer Res 2020 Mar;18(3):448-462 10 Citations |
1 | Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia. (Dou L, Yan F, Pang J, Zheng D, Li D, Gao L, Wang L, Xu Y, Shi J, Wang Q, Zhou L, Shen N, Singh P, Wang L, Li Y, Gao Y, Liu T, Chen C, Al-Kali A, Litzow MR, Chi YI, Bode AM, Liu C, Huang H, Liu D, Marcucci G, Liu S, Yu L) Nat Commun 2019 Nov 07;10(1):5051 16 Citations |
1 | Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines. (Liu N, Wang YA, Sun Y, Ecsedy J, Sun J, Li X, Wang P) Respir Res 2019 Oct 23;20(1):230 24 Citations |
1 | In vivo longitudinal imaging of RNA interference-induced endocrine therapy resistance in breast cancer. (Biswal NC, Fu X, Jagtap JM, Shea MJ, Kumar V, Lords T, Roy R, Schiff R, Joshi A) J Biophotonics 2020 Jan;13(1):e201900180 1 Citation |
2 | Enzalutamide-Induced Feed-Forward Signaling Loop Promotes Therapy-Resistant Prostate Cancer Growth Providing an Exploitable Molecular Target for Jak2 Inhibitors. (Udhane V, Maranto C, Hoang DT, Gu L, Erickson A, Devi S, Talati PG, Banerjee A, Iczkowski KA, Jacobsohn K, See WA, Mirtti T, Kilari D, Nevalainen MT) Mol Cancer Ther 2020 Jan;19(1):231-246 17 Citations |
4 | Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis. (Cheng G, Zhang Q, Pan J, Lee Y, Ouari O, Hardy M, Zielonka M, Myers CR, Zielonka J, Weh K, Chang AC, Chen G, Kresty L, Kalyanaraman B, You M) Nat Commun 2019 May 17;10(1):2205 144 Citations |
1 | Bi2WO6 Semiconductor Nanoplates for Tumor Radiosensitization through High- Z Effects and Radiocatalysis. (Zang Y, Gong L, Mei L, Gu Z, Wang Q) ACS Appl Mater Interfaces 2019 May 29;11(21):18942-18952 70 Citations |
1 | NIR-Light-Activated Combination Therapy with a Precise Ratio of Photosensitizer and Prodrug Using a Host-Guest Strategy. (Chen H, Zeng X, Tham HP, Phua SZF, Cheng W, Zeng W, Shi H, Mei L, Zhao Y) Angew Chem Int Ed Engl 2019 Jun 03;58(23):7641-7646 123 Citations |
2 | Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models. (Papa AL, Jiang A, Korin N, Chen MB, Langan ET, Waterhouse A, Nash E, Caroff J, Graveline A, Vernet A, Mammoto A, Mammoto T, Jain A, Kamm RD, Gounis MJ, Ingber DE) Sci Transl Med 2019 Feb 13;11(479) 54 Citations |
1 | Identification and targeting of novel CDK9 complexes in acute myeloid leukemia. (Beauchamp EM, Abedin SM, Radecki SG, Fischietti M, Arslan AD, Blyth GT, Yang A, Lantz C, Nelson A, Goo YA, Akpan I, Eklund EA, Frankfurt O, Fish EN, Thomas PM, Altman JK, Platanias LC) Blood 2019 Mar 14;133(11):1171-1185 24 Citations |
1 | SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma. (Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, Van Buren G 2nd, McElhany AL, Fisher WE, Lonard DM, O'Malley BW, Wang J) Cancer Lett 2019 Feb 01;442:310-319 19 Citations |
1 | FABP4 as a key determinant of metastatic potential of ovarian cancer. (Gharpure KM, Pradeep S, Sans M, Rupaimoole R, Ivan C, Wu SY, Bayraktar E, Nagaraja AS, Mangala LS, Zhang X, Haemmerle M, Hu W, Rodriguez-Aguayo C, McGuire M, Mak CSL, Chen X, Tran MA, Villar-Prados A, Pena GA, Kondetimmanahalli R, Nini R, Koppula P, Ram P, Liu J, Lopez-Berestein G, Baggerly K, S Eberlin L, Sood AK) Nat Commun 2018 Jul 26;9(1):2923 145 Citations |
1 | miR-137 is a tumor suppressor in endometrial cancer and is repressed by DNA hypermethylation. (Zhang W, Chen JH, Shan T, Aguilera-Barrantes I, Wang LS, Huang TH, Rader JS, Sheng X, Huang YW) Lab Invest 2018 Nov;98(11):1397-1407 58 Citations |
3 | Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes. (Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reyniès A, Dusetti N, Iovanna J, Urrutia R) Nat Commun 2018 May 17;9(1):1978 157 Citations |
1 | Engineering vascularized skeletal muscle tissue with transcriptional factor ETV2-induced autologous endothelial cells. (Yan G, Yan R, Chen C, Chen C, Zhao Y, Qin W, Veldman MB, Li S, Lin S) Protein Cell 2019 Mar;10(3):217-222 8 Citations |
1 | Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation. (Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Carrami EM, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA) Nat Commun 2018 Feb 02;9(1):476 35 Citations |
1 | Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway. (Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, Miao QR, Shao S) Cancer Lett 2018 Apr 01;418:135-146 33 Citations |
1 | Inhibiting Nuclear Phospho-Progesterone Receptor Enhances Antitumor Activity of Onapristone in Uterine Cancer. (Huang Y, Hu W, Huang J, Shen F, Sun Y, Ivan C, Pradeep S, Dood R, Haemmerle M, Jiang D, Mangala LS, Noh K, Hansen JM, Dalton HJ, Previs RA, Nagaraja AS, McGuire M, Jennings NB, Broaddus R, Coleman RL, Sood AK) Mol Cancer Ther 2018 Feb;17(2):464-473 5 Citations |
1 | MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels. (Lu Y, Hu Z, Mangala LS, Stine ZE, Hu X, Jiang D, Xiang Y, Zhang Y, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, DeMarzo AM, Sood AK, Zhang L, Dang CV) Cancer Res 2018 Jan 01;78(1):64-74 82 Citations |
1 | Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP). (Mitamura T, Pradeep S, McGuire M, Wu SY, Ma S, Hatakeyama H, Lyons YA, Hisamatsu T, Noh K, Villar-Prados A, Chen X, Ivan C, Rodriguez-Aguayo C, Hu W, Lopez-Berestein G, Coleman RL, Sood AK) Oncogene 2018 Feb 08;37(6):722-731 31 Citations |
1 | Platelets reduce anoikis and promote metastasis by activating YAP1 signaling. (Haemmerle M, Taylor ML, Gutschner T, Pradeep S, Cho MS, Sheng J, Lyons YM, Nagaraja AS, Dood RL, Wen Y, Mangala LS, Hansen JM, Rupaimoole R, Gharpure KM, Rodriguez-Aguayo C, Yim SY, Lee JS, Ivan C, Hu W, Lopez-Berestein G, Wong ST, Karlan BY, Levine DA, Liu J, Afshar-Kharghan V, Sood AK) Nat Commun 2017 Aug 21;8(1):310 162 Citations |
1 | Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies. (Previs RA, Armaiz-Pena GN, Ivan C, Dalton HJ, Rupaimoole R, Hansen JM, Lyons Y, Huang J, Haemmerle M, Wagner MJ, Gharpure KM, Nagaraja AS, Filant J, McGuire MH, Noh K, Dorniak PL, Linesch SL, Mangala LS, Pradeep S, Wu SY, Sood AK) J Natl Cancer Inst 2017 Jul 01;109(7) 10 Citations |
1 | The Nogo-B receptor promotes Ras plasma membrane localization and activation. (Zhao B, Hu W, Kumar S, Gonyo P, Rana U, Liu Z, Wang B, Duong WQ, Yang Z, Williams CL, Miao QR) Oncogene 2017 Jun 15;36(24):3406-3416 25 Citations |
1 | TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. (Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS) Aging (Albany NY) 2016 Dec 16;8(12):3507-3519 45 Citations |
1 | Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth. (Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, Nagaraja AS, Haemmerle M, Kyunghee N, Derichsweiler M, Plackemeier T, Mercado-Uribe I, Lopez-Berestein G, Moss T, Ram PT, Liu J, Lu X, Mok SC, Sood AK, Nagrath D) Cell Metab 2016 Nov 08;24(5):685-700 277 Citations |
1 | Suppression of B-RafV600E melanoma cell survival by targeting mitochondria using triphenyl-phosphonium-conjugated nitroxide or ubiquinone. (Hong SK, Starenki D, Wu PK, Park JI) Cancer Biol Ther 2017 Feb;18(2):106-114 20 Citations |
1 | Antiangiogenic and tumour inhibitory effects of downregulating tumour endothelial FABP4. (Harjes U, Bridges E, Gharpure KM, Roxanis I, Sheldon H, Miranda F, Mangala LS, Pradeep S, Lopez-Berestein G, Ahmed A, Fielding B, Sood AK, Harris AL) Oncogene 2017 Feb 16;36(7):912-921 52 Citations |
1 | Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. (Miranda F, Mannion D, Liu S, Zheng Y, Mangala LS, Redondo C, Herrero-Gonzalez S, Xu R, Taylor C, Chedom DF, Carrami EM, Albukhari A, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Salah E, Abdul Azeez KR, Elkins JM, Campo L, Myers KA, Klotz D, Bivona S, Dhar S, Bast RC Jr, Saya H, Choi HG, Gray NS, Fischer R, Kessler BM, Yau C, Sood AK, Motohara T, Knapp S, Ahmed AA) Cancer Cell 2016 Aug 08;30(2):273-289 132 Citations |
1 | First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development. (Jonas O, Calligaris D, Methuku KR, Poe MM, Francois JP, Tranghese F, Changelian A, Sieghart W, Ernst M, Krummel DA, Cook JM, Pomeroy SL, Cima M, Agar NY, Langer R, Sengupta S) J Biomed Nanotechnol 2016 Jun;12(6):1297-302 37 Citations |
2 | Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer. (Chaluvally-Raghavan P, Jeong KJ, Pradeep S, Silva AM, Yu S, Liu W, Moss T, Rodriguez-Aguayo C, Zhang D, Ram P, Liu J, Lu Y, Lopez-Berestein G, Calin GA, Sood AK, Mills GB) Cell Rep 2016 May 17;15(7):1493-1504 75 Citations |
1 | Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2. (Rytelewski M, Maleki Vareki S, Mangala LS, Romanow L, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Figueredo R, Ferguson PJ, Vincent M, Sood AK, Koropatnick JD) Oncotarget 2016 Apr 12;7(15):20825-39 8 Citations |
1 | Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer. (Dwivedi SK, Mustafi SB, Mangala LS, Jiang D, Pradeep S, Rodriguez-Aguayo C, Ling H, Ivan C, Mukherjee P, Calin GA, Lopez-Berestein G, Sood AK, Bhattacharya R) Oncotarget 2016 Mar 22;7(12):15093-104 62 Citations |
1 | The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation. (Hesketh AJ, Maloney C, Behr CA, Edelman MC, Glick RD, Al-Abed Y, Symons M, Soffer SZ, Steinberg BM) PLoS One 2015;10(12):e0145197 15 Citations |
1 | Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis. (Rupaimoole R, Lee J, Haemmerle M, Ling H, Previs RA, Pradeep S, Wu SY, Ivan C, Ferracin M, Dennison JB, Millward NMZ, Nagaraja AS, Gharpure KM, McGuire M, Sam N, Armaiz-Pena GN, Sadaoui NC, Rodriguez-Aguayo C, Calin GA, Drapkin RI, Kovacs J, Mills GB, Zhang W, Lopez-Berestein G, Bhattacharya PK, Sood AK) Cell Rep 2015 Dec 22;13(11):2395-2402 95 Citations |
1 | AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer. (Hong D, Kurzrock R, Kim Y, Woessner R, Younes A, Nemunaitis J, Fowler N, Zhou T, Schmidt J, Jo M, Lee SJ, Yamashita M, Hughes SG, Fayad L, Piha-Paul S, Nadella MV, Mohseni M, Lawson D, Reimer C, Blakey DC, Xiao X, Hsu J, Revenko A, Monia BP, MacLeod AR) Sci Transl Med 2015 Nov 18;7(314):314ra185 338 Citations |
1 | The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. (Pai P, Rachagani S, Lakshmanan I, Macha MA, Sheinin Y, Smith LM, Ponnusamy MP, Batra SK) Mol Oncol 2016 Feb;10(2):224-39 27 Citations |
3 | Antitumor Activity of 3-Indolylmethanamines 31B and PS121912. (Guthrie ML, Sidhu PS, Hill EK, Horan TC, Nandhikonda P, Teske KA, Yuan NY, Sidorko M, Rodali R, Cook JM, Han L, Silvaggi NR, Bikle DD, Moore RG, Singh RK, Arnold LA) Anticancer Res 2015 Nov;35(11):6001-7 7 Citations |
1 | Erythropoietin Stimulates Tumor Growth via EphB4. (Pradeep S, Huang J, Mora EM, Nick AM, Cho MS, Wu SY, Noh K, Pecot CV, Rupaimoole R, Stein MA, Brock S, Wen Y, Xiong C, Gharpure K, Hansen JM, Nagaraja AS, Previs RA, Vivas-Mejia P, Han HD, Hu W, Mangala LS, Zand B, Stagg LJ, Ladbury JE, Ozpolat B, Alpay SN, Nishimura M, Stone RL, Matsuo K, Armaiz-Peña GN, Dalton HJ, Danes C, Goodman B, Rodriguez-Aguayo C, Kruger C, Schneider A, Haghpeykar S, Jaladurgam P, Hung MC, Coleman RL, Liu J, Li C, Urbauer D, Lopez-Berestein G, Jackson DB, Sood AK) Cancer Cell 2015 Nov 09;28(5):610-622 71 Citations |
1 | Targeting c-MYC in Platinum-Resistant Ovarian Cancer. (Reyes-González JM, Armaiz-Peña GN, Mangala LS, Valiyeva F, Ivan C, Pradeep S, Echevarría-Vargas IM, Rivera-Reyes A, Sood AK, Vivas-Mejía PE) Mol Cancer Ther 2015 Oct;14(10):2260-9 92 Citations |
1 | MicroRNA-224 promotes tumor progression in nonsmall cell lung cancer. (Cui R, Meng W, Sun HL, Kim T, Ye Z, Fassan M, Jeon YJ, Li B, Vicentini C, Peng Y, Lee TJ, Luo Z, Liu L, Xu D, Tili E, Jin V, Middleton J, Chakravarti A, Lautenschlaeger T, Croce CM) Proc Natl Acad Sci U S A 2015 Aug 04;112(31):E4288-97 133 Citations |
1 | Orai3 Surface Accumulation and Calcium Entry Evoked by Vascular Endothelial Growth Factor. (Li J, Bruns AF, Hou B, Rode B, Webster PJ, Bailey MA, Appleby HL, Moss NK, Ritchie JE, Yuldasheva NY, Tumova S, Quinney M, McKeown L, Taylor H, Prasad KR, Burke D, O'Regan D, Porter KE, Foster R, Kearney MT, Beech DJ) Arterioscler Thromb Vasc Biol 2015 Sep;35(9):1987-94 29 Citations |
1 | Quantitative single-particle digital autoradiography with α-particle emitters for targeted radionuclide therapy using the iQID camera. (Miller BW, Frost SH, Frayo SL, Kenoyer AL, Santos E, Jones JC, Green DJ, Hamlin DK, Wilbur DS, Fisher DR, Orozco JJ, Press OW, Pagel JM, Sandmaier BM) Med Phys 2015 Jul;42(7):4094-105 45 Citations |
1 | Tumor T1 Relaxation Time for Assessing Response to Bevacizumab Anti-Angiogenic Therapy in a Mouse Ovarian Cancer Model. (Ravoori MK, Nishimura M, Singh SP, Lu C, Han L, Hobbs BP, Pradeep S, Choi HJ, Bankson JA, Sood AK, Kundra V) PLoS One 2015;10(6):e0131095 9 Citations |
4 | p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion. (Qi X, Yin N, Ma S, Lepp A, Tang J, Jing W, Johnson B, Dwinell MB, Chitambar CR, Chen G) Stem Cells 2015 Sep;33(9):2738-47 29 Citations |
1 | Bromodomain and extraterminal inhibition blocks tumor progression and promotes differentiation in neuroblastoma. (Lee S, Rellinger EJ, Kim KW, Craig BT, Romain CV, Qiao J, Chung DH) Surgery 2015 Sep;158(3):819-26 24 Citations |
3 | p38γ MAPK is required for inflammation-associated colon tumorigenesis. (Yin N, Qi X, Tsai S, Lu Y, Basir Z, Oshima K, Thomas JP, Myers CR, Stoner G, Chen G) Oncogene 2016 Feb 25;35(8):1039-48 31 Citations |
1 | XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A. (Miyake T, Pradeep S, Wu SY, Rupaimoole R, Zand B, Wen Y, Gharpure KM, Nagaraja AS, Hu W, Cho MS, Dalton HJ, Previs RA, Taylor ML, Hisamatsu T, Kang Y, Liu T, Shacham S, McCauley D, Hawke DH, Wiktorowicz JE, Coleman RL, Sood AK) Clin Cancer Res 2015 Jul 15;21(14):3286-97 36 Citations |
1 | Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer. (Gonzalez-Villasana V, Fuentes-Mattei E, Ivan C, Dalton HJ, Rodriguez-Aguayo C, Fernandez-de Thomas RJ, Aslan B, Del C Monroig P, Velazquez-Torres G, Previs RA, Pradeep S, Kahraman N, Wang H, Kanlikilicer P, Ozpolat B, Calin G, Sood AK, Lopez-Berestein G) Clin Cancer Res 2015 May 01;21(9):2127-37 61 Citations |
1 | Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis. (Pandey P, Rachagani S, Das S, Seshacharyulu P, Sheinin Y, Naslavsky N, Pan Z, Smith BL, Peters HL, Radhakrishnan P, McKenna NR, Giridharan SS, Haridas D, Kaur S, Hollingsworth MA, MacDonald RG, Meza JL, Caplan S, Batra SK, Solheim JC) Oncotarget 2015 Feb 10;6(4):2064-75 25 Citations |
1 | Photo activation of HPPH encapsulated in "Pocket" liposomes triggers multiple drug release and tumor cell killing in mouse breast cancer xenografts. (Sine J, Urban C, Thayer D, Charron H, Valim N, Tata DB, Schiff R, Blumenthal R, Joshi A, Puri A) Int J Nanomedicine 2015;10:125-45 28 Citations |
2 | Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers. (Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K, Gray J, Dusetti NJ, McGuire SE, Flores ER, Sood AK, Mills GB) Cancer Cell 2014 Dec 08;26(6):863-879 43 Citations |
1 | Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells. (Starenki D, Hong SK, Lloyd RV, Park JI) Oncogene 2015 Aug 27;34(35):4624-34 63 Citations |
1 | Isoliquiritigenin induces apoptosis and inhibits xenograft tumor growth of human lung cancer cells by targeting both wild type and L858R/T790M mutant EGFR. (Jung SK, Lee MH, Lim DY, Kim JE, Singh P, Lee SY, Jeong CH, Lim TG, Chen H, Chi YI, Kundu JK, Lee NH, Lee CC, Cho YY, Bode AM, Lee KW, Dong Z) J Biol Chem 2014 Dec 26;289(52):35839-48 95 Citations |
1 | Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. (Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK) Nat Commun 2014 Oct 29;5:5202 146 Citations |
2 | IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation. (Garcia MN, Grasso D, Lopez-Millan MB, Hamidi T, Loncle C, Tomasini R, Lomberk G, Porteu F, Urrutia R, Iovanna JL) J Clin Invest 2014 Nov;124(11):4709-22 32 Citations |
1 | Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase. (Fu X, Creighton CJ, Biswal NC, Kumar V, Shea M, Herrera S, Contreras A, Gutierrez C, Wang T, Nanda S, Giuliano M, Morrison G, Nardone A, Karlin KL, Westbrook TF, Heiser LM, Anur P, Spellman P, Guichard SM, Smith PD, Davies BR, Klinowska T, Lee AV, Mills GB, Rimawi MF, Hilsenbeck SG, Gray JW, Joshi A, Osborne CK, Schiff R) Breast Cancer Res 2014 Sep 11;16(5):430 63 Citations |
1 | Assessment and optimization of electroporation-assisted tumoral nanoparticle uptake in a nude mouse model of pancreatic ductal adenocarcinoma. (West DL, White SB, Zhang Z, Larson AC, Omary RA) Int J Nanomedicine 2014;9:4169-76 16 Citations |
1 | Sub-100nm gold nanomatryoshkas improve photo-thermal therapy efficacy in large and highly aggressive triple negative breast tumors. (Ayala-Orozco C, Urban C, Bishnoi S, Urban A, Charron H, Mitchell T, Shea M, Nanda S, Schiff R, Halas N, Joshi A) J Control Release 2014 Oct 10;191:90-97 82 Citations |
2 | Hematogenous metastasis of ovarian cancer: rethinking mode of spread. (Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK) Cancer Cell 2014 Jul 14;26(1):77-91 238 Citations |
1 | Au nanomatryoshkas as efficient near-infrared photothermal transducers for cancer treatment: benchmarking against nanoshells. (Ayala-Orozco C, Urban C, Knight MW, Urban AS, Neumann O, Bishnoi SW, Mukherjee S, Goodman AM, Charron H, Mitchell T, Shea M, Roy R, Nanda S, Schiff R, Halas NJ, Joshi A) ACS Nano 2014 Jun 24;8(6):6372-81 315 Citations |
1 | Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer. (Gharpure KM, Chu KS, Bowerman CJ, Miyake T, Pradeep S, Mangala SL, Han HD, Rupaimoole R, Armaiz-Pena GN, Rahhal TB, Wu SY, Luft JC, Napier ME, Lopez-Berestein G, DeSimone JM, Sood AK) Mol Cancer Ther 2014 Jul;13(7):1750-7 28 Citations |
1 | Notch3 pathway alterations in ovarian cancer. (Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK) Cancer Res 2014 Jun 15;74(12):3282-93 58 Citations |
1 | Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression. (Hale JS, Otvos B, Sinyuk M, Alvarado AG, Hitomi M, Stoltz K, Wu Q, Flavahan W, Levison B, Johansen ML, Schmitt D, Neltner JM, Huang P, Ren B, Sloan AE, Silverstein RL, Gladson CL, DiDonato JA, Brown JM, McIntyre T, Hazen SL, Horbinski C, Rich JN, Lathia JD) Stem Cells 2014 Jul;32(7):1746-58 166 Citations |
1 | 2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. (Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK) Nat Commun 2014 Mar 12;5:3459 106 Citations |
1 | The surprising in vivo instability of near-IR-absorbing hollow Au-Ag nanoshells. (Goodman AM, Cao Y, Urban C, Neumann O, Ayala-Orozco C, Knight MW, Joshi A, Nordlander P, Halas NJ) ACS Nano 2014 Apr 22;8(4):3222-31 143 Citations |
1 | CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis. (James MA, Vikis HG, Tate E, Rymaszewski AL, You M) Cancer Res 2014 Feb 15;74(4):1116-27 53 Citations |
1 | Down regulation of SPAG9 reduces growth and invasive potential of triple-negative breast cancer cells: possible implications in targeted therapy. (Sinha A, Agarwal S, Parashar D, Verma A, Saini S, Jagadish N, Ansari AS, Lohiya NK, Suri A) J Exp Clin Cancer Res 2013 Sep 19;32(1):69 41 Citations |
1 | Targeting SRC and tubulin in mucinous ovarian carcinoma. (Liu T, Hu W, Dalton HJ, Choi HJ, Huang J, Kang Y, Pradeep S, Miyake T, Song JH, Wen Y, Lu C, Pecot CV, Bottsford-Miller J, Zand B, Jennings NB, Ivan C, Gallick GE, Baggerly KA, Hangauer DG, Coleman RL, Frumovitz M, Sood AK) Clin Cancer Res 2013 Dec 01;19(23):6532-43 33 Citations |
1 | Targeting pancreatic cancer with magneto-fluorescent theranostic gold nanoshells. (Chen W, Ayala-Orozco C, Biswal NC, Perez-Torres C, Bartels M, Bardhan R, Stinnet G, Liu XD, Ji B, Deorukhkar A, Brown LV, Guha S, Pautler RG, Krishnan S, Halas NJ, Joshi A) Nanomedicine (Lond) 2014;9(8):1209-22 59 Citations |
1 | Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. (Kang Y, Hu W, Ivan C, Dalton HJ, Miyake T, Pecot CV, Zand B, Liu T, Huang J, Jennings NB, Rupaimoole R, Taylor M, Pradeep S, Wu SY, Lu C, Wen Y, Huang J, Liu J, Sood AK) J Natl Cancer Inst 2013 Oct 02;105(19):1485-95 151 Citations |
1 | Non-covalent assembly of meso-tetra-4-pyridyl porphine with single-stranded DNA to form nano-sized complexes with hydrophobicity-dependent DNA release and anti-tumor activity. (Ghosh S, Ucer KB, D'Agostino R Jr, Grant K, Sirintrapun J, Thomas MJ, Hantgan R, Bharadwaj M, Gmeiner WH) Nanomedicine 2014 Feb;10(2):451-61 14 Citations |
1 | Activation of MAPK pathways due to DUSP4 loss promotes cancer stem cell-like phenotypes in basal-like breast cancer. (Balko JM, Schwarz LJ, Bhola NE, Kurupi R, Owens P, Miller TW, Gómez H, Cook RS, Arteaga CL) Cancer Res 2013 Oct 15;73(20):6346-58 119 Citations |
2 | Role of collagen matrix in tumor angiogenesis and glioblastoma multiforme progression. (Mammoto T, Jiang A, Jiang E, Panigrahy D, Kieran MW, Mammoto A) Am J Pathol 2013 Oct;183(4):1293-1305 125 Citations |
1 | GATA2 and Lmo2 control angiogenesis and lymphangiogenesis via direct transcriptional regulation of neuropilin-2. (Coma S, Allard-Ratick M, Akino T, van Meeteren LA, Mammoto A, Klagsbrun M) Angiogenesis 2013 Oct;16(4):939-52 44 Citations |
1 | A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. (Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, Patient R, Sood AK, Banham AH, Harris AL, Buffa FM) Cancer Cell 2013 Aug 12;24(2):229-41 214 Citations |
1 | Gene silencing of A-kinase anchor protein 4 inhibits cervical cancer growth in vitro and in vivo. (Saini S, Agarwal S, Sinha A, Verma A, Parashar D, Gupta N, Ansari AS, Lohiya NK, Jagadish N, Suri A) Cancer Gene Ther 2013 Jul;20(7):413-20 22 Citations |
1 | A novel anti-tumor inhibitor identified by virtual screen with PLK1 structure and zebrafish assay. (Lu J, Xin S, Meng H, Veldman M, Schoenfeld D, Che C, Yan R, Zhong H, Li S, Lin S) PLoS One 2013;8(4):e53317 15 Citations |
1 | Mitochondria-targeted nitroxide, Mito-CP, suppresses medullary thyroid carcinoma cell survival in vitro and in vivo. (Starenki D, Park JI) J Clin Endocrinol Metab 2013 Apr;98(4):1529-40 40 Citations |
1 | Visualizing the prostate gland by MR imaging in young and old mice. (Ravoori M, Duggal J, Gagea M, Han L, Singh S, Liu P, Wei W, Ragan DK, Bankson JA, Ma J, Kundra V) PLoS One 2013;8(3):e55746 4 Citations |
1 | Brief report: Mesenchymal stromal cell atrophy in coculture increases aggressiveness of transformed cells. (Castellone MD, Laatikainen LE, Laurila JP, Langella A, Hematti P, Soricelli A, Salvatore M, Laukkanen MO) Stem Cells 2013 Jun;31(6):1218-23 22 Citations |
1 | Ocimum gratissimum retards breast cancer growth and progression and is a natural inhibitor of matrix metalloproteases. (Nangia-Makker P, Raz T, Tait L, Shekhar MP, Li H, Balan V, Makker H, Fridman R, Maddipati K, Raz A) Cancer Biol Ther 2013 May;14(5):417-27 29 Citations |
1 | Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein. (Shimizu A, Nakayama H, Wang P, König C, Akino T, Sandlund J, Coma S, Italiano JE Jr, Mammoto A, Bielenberg DR, Klagsbrun M) J Biol Chem 2013 Jan 25;288(4):2210-22 83 Citations |
1 | Mechanistic basis for overcoming platinum resistance using copper chelating agents. (Liang ZD, Long Y, Tsai WB, Fu S, Kurzrock R, Gagea-Iurascu M, Zhang F, Chen HH, Hennessy BT, Mills GB, Savaraj N, Kuo MT) Mol Cancer Ther 2012 Nov;11(11):2483-94 66 Citations |
1 | PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors. (Meric-Bernstam F, Akcakanat A, Chen H, Do KA, Sangai T, Adkins F, Gonzalez-Angulo AM, Rashid A, Crosby K, Dong M, Phan AT, Wolff RA, Gupta S, Mills GB, Yao J) Clin Cancer Res 2012 Mar 15;18(6):1777-89 186 Citations |
3 | Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases. (Lomberk G, Mathison AJ, Grzenda A, Seo S, DeMars CJ, Rizvi S, Bonilla-Velez J, Calvo E, Fernandez-Zapico ME, Iovanna J, Buttar NS, Urrutia R) J Biol Chem 2012 Apr 13;287(16):13026-39 45 Citations |
1 | Limitation of in vivo models investigating angiogenesis in breast cancer. (Gehmert S, Gehmert S, Bai X, Klein S, Ortmann O, Prantl L) Clin Hemorheol Microcirc 2011;49(1-4):519-26 11 Citations |
1 | Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells. (Sun Y, Zheng S, Torossian A, Speirs CK, Schleicher S, Giacalone NJ, Carbone DP, Zhao Z, Lu B) Int J Radiat Oncol Biol Phys 2012 Mar 01;82(3):e563-72 61 Citations |
1 | Effect of dietary polyunsaturated fatty acids on castration-resistant Pten-null prostate cancer. (Wang S, Wu J, Suburu J, Gu Z, Cai J, Axanova LS, Cramer SD, Thomas MJ, Perry DL, Edwards IJ, Mucci LA, Sinnott JA, Loda MF, Sui G, Berquin IM, Chen YQ) Carcinogenesis 2012 Feb;33(2):404-12 43 Citations |
1 | ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer. (Miller TW, Balko JM, Fox EM, Ghazoui Z, Dunbier A, Anderson H, Dowsett M, Jiang A, Smith RA, Maira SM, Manning HC, González-Angulo AM, Mills GB, Higham C, Chanthaphaychith S, Kuba MG, Miller WR, Shyr Y, Arteaga CL) Cancer Discov 2011 Sep;1(4):338-51 260 Citations |
1 | A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer. (Fox EM, Miller TW, Balko JM, Kuba MG, Sánchez V, Smith RA, Liu S, González-Angulo AM, Mills GB, Ye F, Shyr Y, Manning HC, Buck E, Arteaga CL) Cancer Res 2011 Nov 01;71(21):6773-84 131 Citations |
1 | An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma. (Atkinson JM, Shelat AA, Carcaboso AM, Kranenburg TA, Arnold LA, Boulos N, Wright K, Johnson RA, Poppleton H, Mohankumar KM, Féau C, Phoenix T, Gibson P, Zhu L, Tong Y, Eden C, Ellison DW, Priebe W, Koul D, Yung WK, Gajjar A, Stewart CF, Guy RK, Gilbertson RJ) Cancer Cell 2011 Sep 13;20(3):384-99 93 Citations |
1 | Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer. (Yang X, Turke AB, Qi J, Song Y, Rexer BN, Miller TW, Jänne PA, Arteaga CL, Cantley LC, Engelman JA, Asara JM) Cancer Res 2011 Sep 15;71(18):5965-75 14 Citations |
2 | Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid. (Singh SK, Baumgart S, Singh G, König AO, Reutlinger K, Hofbauer LC, Barth P, Gress TM, Lomberk G, Urrutia R, Fernandez-Zapico ME, Ellenrieder V) J Biol Chem 2011 Aug 19;286(33):28761-28771 22 Citations |
1 | Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells. (Teng IW, Hou PC, Lee KD, Chu PY, Yeh KT, Jin VX, Tseng MJ, Tsai SJ, Chang YS, Wu CS, Sun HS, Tsai KD, Jeng LB, Nephew KP, Huang TH, Hsiao SH, Leu YW) Cancer Res 2011 Jul 01;71(13):4653-63 89 Citations |
1 | Inhibition of JAK2 signaling by TG101209 enhances radiotherapy in lung cancer models. (Sun Y, Moretti L, Giacalone NJ, Schleicher S, Speirs CK, Carbone DP, Lu B) J Thorac Oncol 2011 Apr;6(4):699-706 |
1 | A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth. (Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, Almada LL, Han JJ, Mukhopadhyay D, Ordog T, Buttar NS, Urrutia R) Biochem J 2011 Apr 15;435(2):529-37 83 Citations |
1 | MS-275 sensitizes TRAIL-resistant breast cancer cells, inhibits angiogenesis and metastasis, and reverses epithelial-mesenchymal transition in vivo. (Srivastava RK, Kurzrock R, Shankar S) Mol Cancer Ther 2010 Dec;9(12):3254-66 111 Citations |
1 | Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment. (Lee YJ, Karl DL, Maduekwe UN, Rothrock C, Ryeom S, D'Amore PA, Yoon SS) Cancer Res 2010 Nov 01;70(21):8357-67 52 Citations |
1 | Therapeutic targeting of C-terminal binding protein in human cancer. (Straza MW, Paliwal S, Kovi RC, Rajeshkumar B, Trenh P, Parker D, Whalen GF, Lyle S, Schiffer CA, Grossman SR) Cell Cycle 2010 Sep 15;9(18):3740-50 52 Citations |
2 | Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. (Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R) Pancreatology 2010;10(4):505-16 |
1 | Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. (Bardsley MR, Horváth VJ, Asuzu DT, Lorincz A, Redelman D, Hayashi Y, Popko LN, Young DL, Lomberk GA, Urrutia RA, Farrugia G, Rubin BP, Ordog T) Gastroenterology 2010 Sep;139(3):942-52 98 Citations |
1 | Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents. (Konson A, Pradeep S, Seger R) Cancer Res 2010 Aug 01;70(15):6247-57 33 Citations |
1 | Salirasib in the treatment of pancreatic cancer. (Bustinza-Linares E, Kurzrock R, Tsimberidou AM) Future Oncol 2010 Jun;6(6):885-91 41 Citations |
1 | Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin. (Klenotic PA, Huang P, Palomo J, Kaur B, Van Meir EG, Vogelbaum MA, Febbraio M, Gladson CL, Silverstein RL) Am J Pathol 2010 Apr;176(4):2039-50 43 Citations |
1 | Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth. (Alexanian A, Rufanova VA, Miller B, Flasch A, Roman RJ, Sorokin A) Anticancer Res 2009 Oct;29(10):3819-24 45 Citations |
1 | Molecular imaging of gefitinib activity in an epidermal growth factor receptor (EGFR)-bearing xenograft model. (Gong J, Yang DJ, Kohanim S, Angelo LS, Kurzrock R) Cancer Biol Ther 2009 Dec;8(23):2239-47 2 Citations |
1 | TrkBT1 induces liver metastasis of pancreatic cancer cells by sequestering Rho GDP dissociation inhibitor and promoting RhoA activation. (Li Z, Chang Z, Chiao LJ, Kang Y, Xia Q, Zhu C, Fleming JB, Evans DB, Chiao PJ) Cancer Res 2009 Oct 01;69(19):7851-9 43 Citations |
1 | Imaging biomarkers predict response to anti-HER2 (ErbB2) therapy in preclinical models of breast cancer. (Shah C, Miller TW, Wyatt SK, McKinley ET, Olivares MG, Sanchez V, Nolting DD, Buck JR, Zhao P, Ansari MS, Baldwin RM, Gore JC, Schiff R, Arteaga CL, Manning HC) Clin Cancer Res 2009 Jul 15;15(14):4712-21 77 Citations |
1 | Determination of minimum effective dose and optimal dosing schedule for liposomal curcumin in a xenograft human pancreatic cancer model. (Mach CM, Mathew L, Mosley SA, Kurzrock R, Smith JA) Anticancer Res 2009 Jun;29(6):1895-9 52 Citations |
1 | Suberoylanilide hydroxamic acid (Zolinza/vorinostat) sensitizes TRAIL-resistant breast cancer cells orthotopically implanted in BALB/c nude mice. (Shankar S, Davis R, Singh KP, Kurzrock R, Ross DD, Srivastava RK) Mol Cancer Ther 2009 Jun;8(6):1596-605 52 Citations |
1 | Secreted interleukin-1alpha induces a metastatic phenotype in pancreatic cancer by sustaining a constitutive activation of nuclear factor-kappaB. (Melisi D, Niu J, Chang Z, Xia Q, Peng B, Ishiyama S, Evans DB, Chiao PJ) Mol Cancer Res 2009 May;7(5):624-33 77 Citations |
1 | Molecular imaging of Bcr-Abl phosphokinase in a xenograft model. (Wu JY, Yang DJ, Angelo LS, Kohanim S, Kurzrock R) Mol Cancer Ther 2009 Mar;8(3):703-10 5 Citations |
1 | Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells. (Benavente S, Huang S, Armstrong EA, Chi A, Hsu KT, Wheeler DL, Harari PM) Clin Cancer Res 2009 Mar 01;15(5):1585-92 85 Citations |
1 | Vasculostatin inhibits intracranial glioma growth and negatively regulates in vivo angiogenesis through a CD36-dependent mechanism. (Kaur B, Cork SM, Sandberg EM, Devi NS, Zhang Z, Klenotic PA, Febbraio M, Shim H, Mao H, Tucker-Burden C, Silverstein RL, Brat DJ, Olson JJ, Van Meir EG) Cancer Res 2009 Feb 01;69(3):1212-20 91 Citations |
1 | Biological surgery: synergetic angiogenic therapy using coadministration of two progenitor cell populations. (Li W, Silverstein RL) Circ Res 2008 Sep 26;103(7):684-6 |
1 | Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. (Rizzo P, Miao H, D'Souza G, Osipo C, Song LL, Yun J, Zhao H, Mascarenhas J, Wyatt D, Antico G, Hao L, Yao K, Rajan P, Hicks C, Siziopikou K, Selvaggi S, Bashir A, Bhandari D, Marchese A, Lendahl U, Qin JZ, Tonetti DA, Albain K, Nickoloff BJ, Miele L) Cancer Res 2008 Jul 01;68(13):5226-35 301 Citations |
1 | Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model. (Hobbs JE, Zakarija A, Cundiff DL, Doll JA, Hymen E, Cornwell M, Crawford SE, Liu N, Signaevsky M, Soff GA) Thromb Res 2007;120 Suppl 2:S13-21 77 Citations |
1 | CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. (Opavsky R, Wang SH, Trikha P, Raval A, Huang Y, Wu YZ, Rodriguez B, Keller B, Liyanarachchi S, Wei G, Davuluri RV, Weinstein M, Felsher D, Ostrowski M, Leone G, Plass C) PLoS Genet 2007 Sep;3(9):1757-69 37 Citations |
1 | Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer. (Cheng YY, Yu J, Wong YP, Man EP, To KF, Jin VX, Li J, Tao Q, Sung JJ, Chan FK, Leung WK) Br J Cancer 2007 Oct 08;97(7):895-901 116 Citations |
1 | Feasibility of multiple-mouse dynamic contrast-enhanced MRI. (Ramirez MS, Ragan DK, Kundra V, Bankson JA) Magn Reson Med 2007 Sep;58(3):610-5 13 Citations |
1 | Celecoxib toxicity is cell cycle phase specific. (Bock JM, Menon SG, Sinclair LL, Bedford NS, Goswami PC, Domann FE, Trask DK) Cancer Res 2007 Apr 15;67(8):3801-8 37 Citations |
1 | Liposomal curcumin with and without oxaliplatin: effects on cell growth, apoptosis, and angiogenesis in colorectal cancer. (Li L, Ahmed B, Mehta K, Kurzrock R) Mol Cancer Ther 2007 Apr;6(4):1276-82 311 Citations |
1 | Elevated expression of vascular endothelial growth factor correlates with increased angiogenesis and decreased progression-free survival among patients with low-grade neuroendocrine tumors. (Zhang J, Jia Z, Li Q, Wang L, Rashid A, Zhu Z, Evans DB, Vauthey JN, Xie K, Yao JC) Cancer 2007 Apr 15;109(8):1478-86 177 Citations |
1 | Novel in vivo imaging shows up-regulation of death receptors by paclitaxel and correlates with enhanced antitumor effects of receptor agonist antibodies. (Gong J, Yang D, Kohanim S, Humphreys R, Broemeling L, Kurzrock R) Mol Cancer Ther 2006 Dec;5(12):2991-3000 33 Citations |
1 | Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells. (Khanbolooki S, Nawrocki ST, Arumugam T, Andtbacka R, Pino MS, Kurzrock R, Logsdon CD, Abbruzzese JL, McConkey DJ) Mol Cancer Ther 2006 Sep;5(9):2251-60 124 Citations |
1 | Androgen deprivation induces human prostate epithelial neuroendocrine differentiation of androgen-sensitive LNCaP cells. (Yuan TC, Veeramani S, Lin FF, Kondrikou D, Zelivianski S, Igawa T, Karan D, Batra SK, Lin MF) Endocr Relat Cancer 2006 Mar;13(1):151-67 124 Citations |
1 | Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer. (Strock CJ, Park JI, Rosen DM, Ruggeri B, Denmeade SR, Ball DW, Nelkin BD) J Clin Endocrinol Metab 2006 Jan;91(1):79-84 42 Citations |
1 | Improved excitation light rejection enhances small-animal fluorescent optical imaging. (Hwang K, Houston JP, Rasmussen JC, Joshi A, Ke S, Li C, Sevick-Muraca EM) Mol Imaging 2005;4(3):194-204 35 Citations |
1 | Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice. (Bauer TW, Liu W, Fan F, Camp ER, Yang A, Somcio RJ, Bucana CD, Callahan J, Parry GC, Evans DB, Boyd DD, Mazar AP, Ellis LM) Cancer Res 2005 Sep 01;65(17):7775-81 133 Citations |
1 | Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors. (Gray MJ, Wey JS, Belcheva A, McCarty MF, Trevino JG, Evans DB, Ellis LM, Gallick GE) Cancer Res 2005 May 01;65(9):3664-70 82 Citations |
1 | Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin. (Sclabas GM, Uwagawa T, Schmidt C, Hess KR, Evans DB, Abbruzzese JL, Chiao PJ) Cancer 2005 Jun 15;103(12):2485-90 67 Citations |
1 | Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells. (Sclabas GM, Fujioka S, Schmidt C, Li Z, Frederick WA, Yang W, Yokoi K, Evans DB, Abbruzzese JL, Hess KR, Zhang W, Fidler IJ, Chiao PJ) Clin Cancer Res 2005 Jan 15;11(2 Pt 1):440-9 120 Citations |
1 | Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model. (Hwang RF, Yokoi K, Bucana CD, Tsan R, Killion JJ, Evans DB, Fidler IJ) Clin Cancer Res 2003 Dec 15;9(17):6534-44 154 Citations |
2 | Estrogen receptor inhibits c-Jun-dependent stress-induced cell death by binding and modifying c-Jun activity in human breast cancer cells. (Qi X, Borowicz S, Pramanik R, Schultz RM, Han J, Chen G) J Biol Chem 2004 Feb 20;279(8):6769-77 29 Citations |
1 | Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas. (Karan D, Lin FC, Bryan M, Ringel J, Moniaux N, Lin MF, Batra SK) Int J Oncol 2003 Nov;23(5):1365-71 75 Citations |
1 | CEP-701 and CEP-751 inhibit constitutively activated RET tyrosine kinase activity and block medullary thyroid carcinoma cell growth. (Strock CJ, Park JI, Rosen M, Dionne C, Ruggeri B, Jones-Bolin S, Denmeade SR, Ball DW, Nelkin BD) Cancer Res 2003 Sep 01;63(17):5559-63 91 Citations |
1 | Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. (Doll JA, Stellmach VM, Bouck NP, Bergh AR, Lee C, Abramson LP, Cornwell ML, Pins MR, Borensztajn J, Crawford SE) Nat Med 2003 Jun;9(6):774-80 271 Citations |
1 | Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice. (Solorzano CC, Hwang R, Baker CH, Bucana CD, Pisters PW, Evans DB, Killion JJ, Fidler IJ) Clin Cancer Res 2003 May;9(5):1858-67 37 Citations |
1 | Radiation increases the activity of oncolytic adenovirus cancer gene therapy vectors that overexpress the ADP (E3-11.6K) protein. (Toth K, Tarakanova V, Doronin K, Ward P, Kuppuswamy M, Locke JE, Dawson JE, Kim HJ, Wold WS) Cancer Gene Ther 2003 Mar;10(3):193-200 40 Citations |
1 | Wilms' tumor growth is suppressed by antiangiogenic pigment epithelium-derived factor in a xenograft model. (Abramson LP, Stellmach V, Doll JA, Cornwell M, Arensman RM, Crawford SE) J Pediatr Surg 2003 Mar;38(3):336-42; discussion 336-42 61 Citations |
1 | Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis. (Fujioka S, Sclabas GM, Schmidt C, Niu J, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ) Oncogene 2003 Mar 06;22(9):1365-70 152 Citations |
1 | Function of nuclear factor kappaB in pancreatic cancer metastasis. (Fujioka S, Sclabas GM, Schmidt C, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ) Clin Cancer Res 2003 Jan;9(1):346-54 213 Citations |
1 | Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. (Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ) Clin Cancer Res 2002 Nov;8(11):3628-38 59 Citations |
1 | Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model. (Igawa T, Lin FF, Lee MS, Karan D, Batra SK, Lin MF) Prostate 2002 Mar 01;50(4):222-35 165 Citations |
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