Medical College of Wisconsin
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Publications indexed to the term Organoids

FacultyTitle
1Self-amplifying NRF2-EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer. (Antonucci L, Li N, Duran A, Cobo I, Nicoletti C, Watari K, Nandi SP, Zhu F, Zhao Y, Riahi I, Tsuda M, Shah VM, Morgan T, Waugh T, Caputo L, Liu Y, Rundberg Nilsson A, Xian H, Todoric J, Gu L, Sanchez-Lopez E, Eibl G, Vucic EA, Krawczyk M, Xu Q, Lowy AM, Hatzivassiliou G, Roose-Girma M, Skowronska-Krawczyk D, Scott DA, Bar-Sagi D, Tamayo P, Wu Y, Sears RC, Glass CK, Alexandrov LB, Puri PL, Dawson DW, Hu Y, Diaz-Meco MT, Moscat J, Karin M) Nat Cancer 2025 Jul;6(7):1263-1282       1 Citation
1Adenoviral delivery of the CIITA transgene induces T-cell-mediated killing in glioblastoma organoids. (Salvato I, Klein E, Poli A, Rezaeipour M, Ermini L, Nosirov B, Lipsa A, Oudin A, Baus V, Dore GM, Cosma A, Golebiewska A, Marchini A, Niclou SP) Mol Oncol 2025 Mar;19(3):682-697    
1Recurrent RhoGAP gene fusion CLDN18-ARHGAP26 promotes RHOA activation and focal adhesion kinase and YAP-TEAD signalling in diffuse gastric cancer. (Zhang F, Sahu V, Peng K, Wang Y, Li T, Bala P, Aitymbayev D, Sahgal P, Schaefer A, Der CJ, Ryeom S, Yoon S, Sethi N, Bass AJ, Zhang H) Gut 2024 Jul 11;73(8):1280-1291       19 Citations
2Neutralizing antibodies with neurotropic factor treatment maintain neurodevelopmental gene expression upon exposure to human cytomegalovirus. (O'Brien BS, Mokry RL, Schumacher ML, Rosas-Rogers S, Terhune SS, Ebert AD) J Virol 2023 Oct 31;97(10):e0069623       4 Citations
1Monitoring Effects of Membrane Traffic Via Changes in Cell Polarity and Morphogenesis in Three-Dimensional Human Pluripotent Stem Cell Cysts. (Hamed MM, Taniguchi K, Duncan MC) Methods Mol Biol 2023;2557:83-98       1 Citation
2Nitric Oxide Attenuates Human Cytomegalovirus Infection yet Disrupts Neural Cell Differentiation and Tissue Organization. (Mokry RL, O'Brien BS, Adelman JW, Rosas S, Schumacher ML, Ebert AD, Terhune SS) J Virol 2022 Jul 27;96(14):e0012622       13 Citations
1ATF6 is essential for human cone photoreceptor development. (Kroeger H, Grandjean JMD, Chiang WJ, Bindels DD, Mastey R, Okalova J, Nguyen A, Powers ET, Kelly JW, Grimsey NJ, Michaelides M, Carroll J, Wiseman RL, Lin JH) Proc Natl Acad Sci U S A 2021 Sep 28;118(39)       43 Citations
1Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition. (Waters AM, Khatib TO, Papke B, Goodwin CM, Hobbs GA, Diehl JN, Yang R, Edwards AC, Walsh KH, Sulahian R, McFarland JM, Kapner KS, Gilbert TSK, Stalnecker CA, Javaid S, Barkovskaya A, Grover KR, Hibshman PS, Blake DR, Schaefer A, Nowak KM, Klomp JE, Hayes TK, Kassner M, Tang N, Tanaseichuk O, Chen K, Zhou Y, Kalkat M, Herring LE, Graves LM, Penn LZ, Yin HH, Aguirre AJ, Hahn WC, Cox AD, Der CJ) Cell Rep 2021 Jun 29;35(13):109291       23 Citations
2Modeling alcohol-induced neurotoxicity using human induced pluripotent stem cell-derived three-dimensional cerebral organoids. (Arzua T, Yan Y, Jiang C, Logan S, Allison RL, Wells C, Kumar SN, Schäfer R, Bai X) Transl Psychiatry 2020 Oct 13;10(1):347       79 Citations
1Isolation and Culture of Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoid Cells. (Yan Y, Arzua T, Logan S, Bai X) Methods Mol Biol 2022;2454:483-494       2 Citations
1Stem Cell-Based Disease Modeling and Cell Therapy. (Bai X) Cells 2020 Sep 29;9(10)       27 Citations
2Alcohol-induced CYP2E1, mitochondrial dynamics and retrograde signaling in human hepatic 3D organoids. (Angireddy R, Chowdhury AR, Zielonka J, Ruthel G, Kalyanaraman B, Avadhani NG) Free Radic Biol Med 2020 Nov 01;159:1-14       26 Citations
1Dynamic Characterization of Structural, Molecular, and Electrophysiological Phenotypes of Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids, and Comparison with Fetal and Adult Gene Profiles. (Logan S, Arzua T, Yan Y, Jiang C, Liu X, Yu LK, Liu QS, Bai X) Cells 2020 May 23;9(5)       39 Citations
1Human iPSC-Derived Neurons and Cerebral Organoids Establish Differential Effects of Germline NF1 Gene Mutations. (Anastasaki C, Wegscheid ML, Hartigan K, Papke JB, Kopp ND, Chen J, Cobb O, Dougherty JD, Gutmann DH) Stem Cell Reports 2020 Apr 14;14(4):541-550       59 Citations
1Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy. (Hengel H, Bosso-Lefèvre C, Grady G, Szenker-Ravi E, Li H, Pierce S, Lebigot É, Tan TT, Eio MY, Narayanan G, Utami KH, Yau M, Handal N, Deigendesch W, Keimer R, Marzouqa HM, Gunay-Aygun M, Muriello MJ, Verhelst H, Weckhuysen S, Mahida S, Naidu S, Thomas TG, Lim JY, Tan ES, Haye D, Willemsen MAAP, Oegema R, Mitchell WG, Pierson TM, Andrews MV, Willing MC, Rodan LH, Barakat TS, van Slegtenhorst M, Gavrilova RH, Martinelli D, Gilboa T, Tamim AM, Hashem MO, AlSayed MD, Abdulrahim MM, Al-Owain M, Awaji A, Mahmoud AAH, Faqeih EA, Asmari AA, Algain SM, Jad LA, Aldhalaan HM, Helbig I, Koolen DA, Riess A, Kraegeloh-Mann I, Bauer P, Gulsuner S, Stamberger H, Ng AYJ, Tang S, Tohari S, Keren B, Schultz-Rogers LE, Klee EW, Barresi S, Tartaglia M, Mor-Shaked H, Maddirevula S, Begtrup A, Telegrafi A, Pfundt R, Schüle R, Ciruna B, Bonnard C, Pouladi MA, Stewart JC, Claridge-Chang A, Lefeber DJ, Alkuraya FS, Mathuru AS, Venkatesh B, Barycki JJ, Simpson MA, Jamuar SS, Schöls L, Reversade B) Nat Commun 2020 Jan 30;11(1):595       46 Citations
1Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal. (Kaya KD, Chen HY, Brooks MJ, Kelley RA, Shimada H, Nagashima K, de Val N, Drinnan CT, Gieser L, Kruczek K, Erceg S, Li T, Lukovic D, Adlakha YK, Welby E, Swaroop A) Mol Vis 2019;25:663-678       66 Citations
2Human Cytomegalovirus Disruption of Calcium Signaling in Neural Progenitor Cells and Organoids. (Sison SL, O'Brien BS, Johnson AJ, Seminary ER, Terhune SS, Ebert AD) J Virol 2019 Sep 01;93(17)       52 Citations
2Studying Human Neurological Disorders Using Induced Pluripotent Stem Cells: From 2D Monolayer to 3D Organoid and Blood Brain Barrier Models. (Logan S, Arzua T, Canfield SG, Seminary ER, Sison SL, Ebert AD, Bai X) Compr Physiol 2019 Mar 14;9(2):565-611       115 Citations
1Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond. (Liu C, Oikonomopoulos A, Sayed N, Wu JC) Development 2018 Mar 08;145(5)       232 Citations
1Intracellular fusion of sequentially formed endocytic compartments. (Salzman NH, Maxfield FR) J Cell Biol 1988 Apr;106(4):1083-91       60 Citations
1[Demonstration of an intact complex of epidermal growth factor and its receptor in the endosomes of A-431 cells]. (Kornilova ES, Bobrova IF, Nesterov AM, Nikol'skiĭ NN, Sorokin AB) Tsitologiia 1988 Mar;30(3):291-8       2 Citations