| 1 | Increased Survival in Patients With Molybdenum Cofactor Deficiency Type A Treated With Cyclic Pyranopterin Monophosphate. (Schwarz G, Basel DG, Schwahn BC, Spiegel R, Wong FY, Bliss R, Squires L) J Inherit Metab Dis 2025 Mar;48(2):e70000 1 Citation |
| 2 | Enhancing Radiation Therapy Response in Prostate Cancer Through Metabolic Modulation by Mito-Lonidamine: A 1H and 31P Magnetic Resonance Spectroscopy Study. (Orlovskiy S, Gupta PK, Arias-Mendoza F, Singh DK, Nova S, Nelson DS, Narayan V, Koch CJ, Hardy M, You M, Kalyanaraman B, Nath K) Int J Mol Sci 2025 Jan 09;26(2) |
| 3 | Mitigating gut microbial degradation of levodopa and enhancing brain dopamine: Implications in Parkinson's disease. (Cheng G, Hardy M, Hillard CJ, Feix JB, Kalyanaraman B) Commun Biol 2024 May 30;7(1):668 21 Citations |
| 3 | Synthesis of fluorinated triphenylphosphonium analogs that improve cancer cell selectivity and in vivo detection. (Keyes RF, McAllister D, Dwinell MB, Smith BC) STAR Protoc 2023 Sep 15;4(3):102437 |
| 3 | Redox-crippled MitoQ potently inhibits breast cancer and glioma cell proliferation: A negative control for verifying the antioxidant mechanism of MitoQ in cancer and other oxidative pathologies. (Cheng G, Karoui H, Hardy M, Kalyanaraman B) Free Radic Biol Med 2023 Aug 20;205:175-187 14 Citations |
| 3 | Potent inhibition of tumour cell proliferation and immunoregulatory function by mitochondria-targeted atovaquone. (Cheng G, Hardy M, Topchyan P, Zander R, Volberding P, Cui W, Kalyanaraman B) Sci Rep 2020 Oct 21;10(1):17872 44 Citations |
| 1 | New therapeutic approaches to overcoming resistant EGFR exon 20 alterations. (Li AM, Boichard A, Felip E, Kurzrock R) Crit Rev Oncol Hematol 2020 Jul;151:102990 16 Citations |
| 1 | Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin. (Sherwood AM, Halberstadt AL, Klein AK, McCorvy JD, Kaylo KW, Kargbo RB, Meisenheimer P) J Nat Prod 2020 Feb 28;83(2):461-467 68 Citations |
| 1 | The C terminus of the bacterial multidrug transporter EmrE couples drug binding to proton release. (Thomas NE, Wu C, Morrison EA, Robinson AE, Werner JP, Henzler-Wildman KA) J Biol Chem 2018 Dec 07;293(49):19137-19147 18 Citations |
| 1 | New free-exchange model of EmrE transport. (Robinson AE, Thomas NE, Morrison EA, Balthazor BM, Henzler-Wildman KA) Proc Natl Acad Sci U S A 2017 Nov 21;114(47):E10083-E10091 49 Citations |
| 5 | A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds. (Kalyanaraman B, Cheng G, Hardy M, Ouari O, Lopez M, Joseph J, Zielonka J, Dwinell MB) Redox Biol 2018 Apr;14:316-327 218 Citations |
| 5 | Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications. (Zielonka J, Joseph J, Sikora A, Hardy M, Ouari O, Vasquez-Vivar J, Cheng G, Lopez M, Kalyanaraman B) Chem Rev 2017 Aug 09;117(15):10043-10120 1518 Citations |
| 2 | Effect of mitochondrially targeted carboxy proxyl nitroxide on Akt-mediated survival in Daudi cells: Significance of a dual mode of action. (Variar G, Pant T, Singh A, Ravichandran A, Swami S, Kalyanaraman B, Dhanasekaran A) PLoS One 2017;12(4):e0174546 1 Citation |
| 5 | Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism. (Cheng G, Zielonka J, McAllister D, Hardy M, Ouari O, Joseph J, Dwinell MB, Kalyanaraman B) Cancer Lett 2015 Aug 28;365(1):96-106 71 Citations |
| 1 | A mitochondrial-targeted coenzyme q analog prevents weight gain and ameliorates hepatic dysfunction in high-fat-fed mice. (Fink BD, Herlein JA, Guo DF, Kulkarni C, Weidemann BJ, Yu L, Grobe JL, Rahmouni K, Kerns RJ, Sivitz WI) J Pharmacol Exp Ther 2014 Dec;351(3):699-708 44 Citations |
| 3 | A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2(R1441G)) transgenic mouse model of Parkinson's disease. (Dranka BP, Gifford A, McAllister D, Zielonka J, Joseph J, O'Hara CL, Stucky CL, Kanthasamy AG, Kalyanaraman B) Neurosci Lett 2014 Nov 07;583:159-64 54 Citations |
| 3 | Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model. (Dickey JS, Gonzalez Y, Aryal B, Mog S, Nakamura AJ, Redon CE, Baxa U, Rosen E, Cheng G, Zielonka J, Parekh P, Mason KP, Joseph J, Kalyanaraman B, Bonner W, Herman E, Shacter E, Rao VA) PLoS One 2013;8(8):e70575 62 Citations |
| 2 | Mitochondria-targeted antioxidant and glycolysis inhibition: synergistic therapy in hepatocellular carcinoma. (Dilip A, Cheng G, Joseph J, Kunnimalaiyaan S, Kalyanaraman B, Kunnimalaiyaan M, Gamblin TC) Anticancer Drugs 2013 Oct;24(9):881-8 30 Citations |
| 2 | Real-time monitoring of reactive oxygen and nitrogen species in a multiwell plate using the diagnostic marker products of specific probes. (Zielonka J, Joseph J, Sikora A, Kalyanaraman B) Methods Enzymol 2013;526:145-57 24 Citations |
| 2 | Reaction between peroxynitrite and triphenylphosphonium-substituted arylboronic acid isomers: identification of diagnostic marker products and biological implications. (Sikora A, Zielonka J, Adamus J, Debski D, Dybala-Defratyka A, Michalowski B, Joseph J, Hartley RC, Murphy MP, Kalyanaraman B) Chem Res Toxicol 2013 Jun 17;26(6):856-67 44 Citations |
| 1 | Mitochondria-targeted nitroxide, Mito-CP, suppresses medullary thyroid carcinoma cell survival in vitro and in vivo. (Starenki D, Park JI) J Clin Endocrinol Metab 2013 Apr;98(4):1529-40 44 Citations |
| 1 | Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells. (Cunniff B, Benson K, Stumpff J, Newick K, Held P, Taatjes D, Joseph J, Kalyanaraman B, Heintz NH) J Cell Physiol 2013 Apr;228(4):835-45 40 Citations |
| 2 | Adverse alterations in mitochondrial function contribute to type 2 diabetes mellitus-related endothelial dysfunction in humans. (Kizhakekuttu TJ, Wang J, Dharmashankar K, Ying R, Gutterman DD, Vita JA, Widlansky ME) Arterioscler Thromb Vasc Biol 2012 Oct;32(10):2531-9 95 Citations |
| 1 | Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemia-reperfusion: therapeutic potential of mitochondrially targeted antioxidants. (Mukhopadhyay P, Horváth B, Zsengellėr Z, Bátkai S, Cao Z, Kechrid M, Holovac E, Erdėlyi K, Tanchian G, Liaudet L, Stillman IE, Joseph J, Kalyanaraman B, Pacher P) Free Radic Biol Med 2012 Sep 01;53(5):1123-38 128 Citations |
| 3 | Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death. (Cheng G, Zielonka J, Dranka BP, McAllister D, Mackinnon AC Jr, Joseph J, Kalyanaraman B) Cancer Res 2012 May 15;72(10):2634-44 240 Citations |
| 2 | Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy. (Mukhopadhyay P, Horváth B, Zsengellér Z, Zielonka J, Tanchian G, Holovac E, Kechrid M, Patel V, Stillman IE, Parikh SM, Joseph J, Kalyanaraman B, Pacher P) Free Radic Biol Med 2012 Jan 15;52(2):497-506 194 Citations |
| 4 | Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. (Cheng G, Lopez M, Zielonka J, Hauser AD, Joseph J, McAllister D, Rowe JJ, Sugg SL, Williams CL, Kalyanaraman B) Cancer Biol Ther 2011 Oct 15;12(8):707-17 28 Citations |
| 1 | Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis. (Chacko BK, Srivastava A, Johnson MS, Benavides GA, Chang MJ, Ye Y, Jhala N, Murphy MP, Kalyanaraman B, Darley-Usmar VM) Hepatology 2011 Jul;54(1):153-63 124 Citations |
| 1 | Adverse events in the long-term follow-up of patients treated with samarium Sm 153 lexidronam for osseous metastases. (Paravati AJ, Russo AL, Aitken C) Int J Radiat Oncol Biol Phys 2011 Oct 01;81(2):506-10 7 Citations |
| 2 | Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model. (Ghosh A, Chandran K, Kalivendi SV, Joseph J, Antholine WE, Hillard CJ, Kanthasamy A, Kanthasamy A, Kalyanaraman B) Free Radic Biol Med 2010 Dec 01;49(11):1674-84 186 Citations |
| 2 | The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone. (Rao VA, Klein SR, Bonar SJ, Zielonka J, Mizuno N, Dickey JS, Keller PW, Joseph J, Kalyanaraman B, Shacter E) J Biol Chem 2010 Nov 05;285(45):34447-59 132 Citations |
| 1 | SOD1 and MitoTEMPO partially prevent mitochondrial permeability transition pore opening, necrosis, and mitochondrial apoptosis after ATP depletion recovery. (Liang HL, Sedlic F, Bosnjak Z, Nilakantan V) Free Radic Biol Med 2010 Nov 30;49(10):1550-60 131 Citations |
| 1 | Tandem dosing of samarium-153 ethylenediamine tetramethylene phosphoric acid with stem cell support for patients with high-risk osteosarcoma. (Loeb DM, Hobbs RF, Okoli A, Chen AR, Cho S, Srinivasan S, Sgouros G, Shokek O, Wharam MD Jr, Scott T, Schwartz CL) Cancer 2010 Dec 01;116(23):5470-8 21 Citations |
| 1 | Role of mitochondrial reactive oxygen species in osteoclast differentiation. (Srinivasan S, Koenigstein A, Joseph J, Sun L, Kalyanaraman B, Zaidi M, Avadhani NG) Ann N Y Acad Sci 2010 Mar;1192(1):245-52 121 Citations |
| 1 | Dose-finding study of 153Sm-EDTMP in patients with poor-prognosis osteosarcoma. (Loeb DM, Garrett-Mayer E, Hobbs RF, Prideaux AR, Sgouros G, Shokek O, Wharam MD Jr, Scott T, Schwartz CL) Cancer 2009 Jun 01;115(11):2514-22 47 Citations |
| 3 | Doxorubicin inactivates myocardial cytochrome c oxidase in rats: cardioprotection by Mito-Q. (Chandran K, Aggarwal D, Migrino RQ, Joseph J, McAllister D, Konorev EA, Antholine WE, Zielonka J, Srinivasan S, Avadhani NG, Kalyanaraman B) Biophys J 2009 Feb 18;96(4):1388-98 168 Citations |
| 1 | Tetraalkylphosphonium polyoxometalate ionic liquids: novel, organic-inorganic hybrid materials. (Rickert PG, Antonio MR, Firestone MA, Kubatko KA, Szreder T, Wishart JF, Dietz ML) J Phys Chem B 2007 May 10;111(18):4685-92 164 Citations |
| 1 | Tetraalkylphosphonium polyoxometalates: electroactive, "task-specific" ionic liquids. (Rickert PG, Antonio MR, Firestone MA, Kubatko KA, Szreder T, Wishart JF, Dietz ML) Dalton Trans 2007 Feb 07(5):529-31 71 Citations |
| 1 | Synthesis and ESR studies of a novel cyclic nitrone spin trap attached to a phosphonium group-a suitable trap for mitochondria-generated ROS? (Xu Y, Kalyanaraman B) Free Radic Res 2007 Jan;41(1):1-7 41 Citations |
| 1 | Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide. (Dhanasekaran A, Kotamraju S, Karunakaran C, Kalivendi SV, Thomas S, Joseph J, Kalyanaraman B) Free Radic Biol Med 2005 Sep 01;39(5):567-83 187 Citations |
| 1 | Determining the antiviral activity of tenofovir disoproxil fumarate in treatment-naive chronically HIV-1-infected individuals. (Louie M, Hogan C, Hurley A, Simon V, Chung C, Padte N, Lamy P, Flaherty J, Coakley D, Di Mascio M, Perelson AS, Markowitz M) AIDS 2003 May 23;17(8):1151-6 80 Citations |
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| 1 | Randomized, controlled study of the safety and efficacy of intravenous cidofovir for the treatment of relapsing cytomegalovirus retinitis in patients with AIDS. (Lalezari JP, Holland GN, Kramer F, McKinley GF, Kemper CA, Ives DV, Nelson R, Hardy WD, Kuppermann BD, Northfelt DW, Youle M, Johnson M, Lewis RA, Weinberg DV, Simon GL, Wolitz RA, Ruby AE, Stagg RJ, Jaffe HS) J Acquir Immune Defic Syndr Hum Retrovirol 1998 Apr 01;17(4):339-44 109 Citations |
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