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Publications indexed to the term Polysaccharides

FacultyTitle
1Thermodynamics of calcium binding to heparin: Implications of solvation and water structuring for polysaccharide biofunctions. (Knight BM, Gallagher CMB, Schulz MD, Edgar KJ, McNaul CD, McCutchin CA, Dove PM) Proc Natl Acad Sci U S A 2025 Sep 02;122(35):e2504348122    
1One N-glycan regulates natural killer cell antibody-dependent cell-mediated cytotoxicity and modulates Fc γ receptor IIIa/CD16a structure. (Kremer PG, Lampros EA, Blocker AM, Barb AW) Elife 2024 Oct 25;13    
1O-linked sialic acid residues on platelet membrane glycoprotein IIb mask the human HPA-9b alloepitope. (Zhang N, Sullivan MJ, Curtis BR, Newman PJ) Blood 2023 Nov 30;142(22):1909-1917       1 Citation
1Inhibiting N-glycan processing increases the antibody binding affinity and effector function of human natural killer cells. (Rodriguez Benavente MC, Hughes HB, Kremer PG, Subedi GP, Barb AW) Immunology 2023 Oct;170(2):202-213       7 Citations
2Impaired Response to Polysaccharide Vaccine in Selective IgE Deficiency. (Noonan E, Straesser MD, Makin T, Williams A, Al-Hazaymeh A, Routes JM, Verbsky J, Borish L, Lawrence MG) J Clin Immunol 2023 Aug;43(6):1448-1454       2 Citations
1Mucin glycans drive oral microbial community composition and function. (Wu CM, Wheeler KM, Cárcamo-Oyarce G, Aoki K, McShane A, Datta SS, Mark Welch JL, Tiemeyer M, Griffen AL, Ribbeck K) NPJ Biofilms Microbiomes 2023 Mar 23;9(1):11       29 Citations
1Characterization of the human platelet N- and O-glycome upon storage using tandem mass spectrometry. (Rosenbalm KE, Lee-Sundlov MM, Ashline DJ, Grozovsky R, Aoki K, Hanneman AJS, Hoffmeister KM) Blood Adv 2023 Aug 22;7(16):4278-4290       15 Citations
1Glia-neuron coupling via a bipartite sialylation pathway promotes neural transmission and stress tolerance in Drosophila. (Scott H, Novikov B, Ugur B, Allen B, Mertsalov I, Monagas-Valentin P, Koff M, Baas Robinson S, Aoki K, Veizaj R, Lefeber DJ, Tiemeyer M, Bellen H, Panin V) Elife 2023 Mar 22;12       2 Citations
1Host-derived O-glycans inhibit toxigenic conversion by a virulence-encoding phage in Vibrio cholerae. (Wang BX, Takagi J, McShane A, Park JH, Aoki K, Griffin C, Teschler J, Kitts G, Minzer G, Tiemeyer M, Hevey R, Yildiz F, Ribbeck K) EMBO J 2023 Feb 01;42(3):e111562       22 Citations
1Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques. (Tolbert WD, Gohain N, Kremer PG, Hederman AP, Nguyen DN, Van V, Sherburn R, Lewis GK, Finzi A, Pollara J, Ackerman ME, Barb AW, Pazgier M) Front Immunol 2022;13:960411       11 Citations
1The weaker-binding Fc γ receptor IIIa F158 allotype retains sensitivity to N-glycan composition and exhibits a destabilized antibody-binding interface. (Kremer PG, Barb AW) J Biol Chem 2022 Sep;298(9):102329       12 Citations
1Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity. (Takagi J, Aoki K, Turner BS, Lamont S, Lehoux S, Kavanaugh N, Gulati M, Valle Arevalo A, Lawrence TJ, Kim CY, Bakshi B, Ishihara M, Nobile CJ, Cummings RD, Wozniak DJ, Tiemeyer M, Hevey R, Ribbeck K) Nat Chem Biol 2022 Jul;18(7):762-773       76 Citations
1Clinical impact of glycans in platelet and megakaryocyte biology. (Falet H, Rivadeneyra L, Hoffmeister KM) Blood 2022 Jun 02;139(22):3255-3263       14 Citations
1Circulating platelet count and glycans. (Rivadeneyra L, Falet H, Hoffmeister KM) Curr Opin Hematol 2021 Nov 01;28(6):431-437       6 Citations
2Immune cells surveil aberrantly sialylated O-glycans on megakaryocytes to regulate platelet count. (Lee-Sundlov MM, Burns RT, Kim TO, Grozovsky R, Giannini S, Rivadeneyra L, Zheng Y, Glabere SH, Kahr WHA, Abdi R, Despotovic JM, Wang D, Hoffmeister KM) Blood 2021 Dec 09;138(23):2408-2424       24 Citations
1Mucin O-glycans suppress quorum-sensing pathways and genetic transformation in Streptococcus mutans. (Werlang CA, Chen WG, Aoki K, Wheeler KM, Tymm C, Mileti CJ, Burgos AC, Kim K, Tiemeyer M, Ribbeck K) Nat Microbiol 2021 May;6(5):574-583       59 Citations
1Global mapping of glycosylation pathways in human-derived cells. (Huang YF, Aoki K, Akase S, Ishihara M, Liu YS, Yang G, Kizuka Y, Mizumoto S, Tiemeyer M, Gao XD, Aoki-Kinoshita KF, Fujita M) Dev Cell 2021 Apr 19;56(8):1195-1209.e7       84 Citations
1Characterization and statistical modeling of glycosylation changes in sickle cell disease. (Ashwood HE, Ashwood C, Schmidt AP, Gundry RL, Hoffmeister KM, Anani WQ) Blood Adv 2021 Mar 09;5(5):1463-1473       9 Citations
1Modified tamarind kernel polysaccharide-based matrix alters neuro-keratinocyte cross-talk and serves as a suitable scaffold for skin tissue engineering. (Choudhury P, Chawla S, Agarwal S, Singh A, Nayak A, Kumar A, Maji PK, Goswami C, Goswami L) Mater Sci Eng C Mater Biol Appl 2021 Feb;121:111779       5 Citations
1Predictive modeling of complex ABO glycan phenotypes by lectin microarrays. (Anani WQ, Ashwood HE, Schmidt A, Burns RT, Denomme GA, Hoffmeister KM) Blood Adv 2020 Aug 25;4(16):3960-3970       6 Citations
1Desialylation of O-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance. (Wang Y, Chen W, Zhang W, Lee-Sundlov MM, Casari C, Berndt MC, Lanza F, Bergmeier W, Hoffmeister KM, Zhang XF, Li R) Haematologica 2021 Jan 01;106(1):220-229       32 Citations
1The HMW2 adhesin of non-typeable Haemophilus influenzae is a human-adapted lectin that mediates high-affinity binding to 2-6 linked N-acetylneuraminic acid glycans. (Atack JM, Day CJ, Poole J, Brockman KL, Bakaletz LO, Barenkamp SJ, Jennings MP) Biochem Biophys Res Commun 2018 Sep 05;503(2):1103-1107       18 Citations
1Airway glycomic and allergic inflammatory consequences resulting from keratan sulfate galactose 6-O-sulfotransferase (CHST1) deficiency. (Kumagai T, Kiwamoto T, Brummet ME, Wu F, Aoki K, Zhu Z, Bochner BS, Tiemeyer M) Glycobiology 2018 Jun 01;28(6):406-417       16 Citations
1Hydroxyethyl methacrylate grafted carboxy methyl tamarind (CMT-g-HEMA) polysaccharide based matrix as a suitable scaffold for skin tissue engineering. (Choudhury P, Kumar S, Singh A, Kumar A, Kaur N, Sanyasi S, Chawla S, Goswami C, Goswami L) Carbohydr Polym 2018 Jun 01;189:87-98       29 Citations
1Glucuronylated core 1 glycans are required for precise localization of neuromuscular junctions and normal formation of basement membranes on Drosophila muscles. (Itoh K, Akimoto Y, Kondo S, Ichimiya T, Aoki K, Tiemeyer M, Nishihara S) Dev Biol 2018 Apr 15;436(2):108-124       16 Citations
1GlyTouCan: an accessible glycan structure repository. (Tiemeyer M, Aoki K, Paulson J, Cummings RD, York WS, Karlsson NG, Lisacek F, Packer NH, Campbell MP, Aoki NP, Fujita A, Matsubara M, Shinmachi D, Tsuchiya S, Yamada I, Pierce M, Ranzinger R, Narimatsu H, Aoki-Kinoshita KF) Glycobiology 2017 Oct 01;27(10):915-919       140 Citations
1The importance of N-glycosylation on β3 integrin ligand binding and conformational regulation. (Cai X, Thinn AMM, Wang Z, Shan H, Zhu J) Sci Rep 2017 Jul 05;7(1):4656       63 Citations
1Circulating blood and platelets supply glycosyltransferases that enable extrinsic extracellular glycosylation. (Lee-Sundlov MM, Ashline DJ, Hanneman AJ, Grozovsky R, Reinhold VN, Hoffmeister KM, Lau JT) Glycobiology 2017 Jan;27(2):188-198       60 Citations
4The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function. (Lertkiatmongkol P, Paddock C, Newman DK, Zhu J, Thomas MJ, Newman PJ) J Biol Chem 2016 Dec 09;291(50):26216-26225       29 Citations
1A Modified Polysaccharide-Based Hydrogel for Enhanced Osteogenic Maturation and Mineralization Independent of Differentiation Factors. (Sanyasi S, Kumar S, Ghosh A, Majhi RK, Kaur N, Choudhury P, Singh UP, Goswami C, Goswami L) Macromol Biosci 2017 Mar;17(3)       19 Citations
1Mass Spectrometric Quantification of N-Linked Glycans by Reference to Exogenous Standards. (Mehta N, Porterfield M, Struwe WB, Heiss C, Azadi P, Rudd PM, Tiemeyer M, Aoki K) J Proteome Res 2016 Sep 02;15(9):2969-80       37 Citations
1Blocking inhibition of prothrombinase by tissue factor pathway inhibitor alpha: a procoagulant property of heparins. (Wood JP, Baumann Kreuziger LM, Desai UR, Mast AE) Br J Haematol 2016 Oct;175(1):123-32       4 Citations
2Glycans and the platelet life cycle. (Li R, Hoffmeister KM, Falet H) Platelets 2016 Sep;27(6):505-11       65 Citations
2Thymidylate Limitation Potentiates Cephalosporin Activity toward Enterococci via an Exopolysaccharide-Based Mechanism. (Hoff JS, Kristich CJ) ACS Chem Biol 2016 Jun 17;11(6):1561-8       11 Citations
1Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model. (Parkinson WM, Dookwah M, Dear ML, Gatto CL, Aoki K, Tiemeyer M, Broadie K) Dis Model Mech 2016 May 01;9(5):513-27       31 Citations
1The association and aggregation of the metamorphic chemokine lymphotactin with fondaparinux: from nm molecular complexes to μm molecular assemblies. (Harvey SR, MacPhee CE, Volkman BF, Barran PE) Chem Commun (Camb) 2016 Jan 07;52(2):394-7       4 Citations
2Regulating billions of blood platelets: glycans and beyond. (Grozovsky R, Giannini S, Falet H, Hoffmeister KM) Blood 2015 Oct 15;126(16):1877-84       138 Citations
1Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway. (Gong J, Sun F, Li Y, Zhou X, Duan Z, Duan F, Zhao L, Chen H, Qi S, Shen J) Neuropharmacology 2015 Apr;91:123-34       97 Citations
1Improved in-gel reductive β-elimination for comprehensive O-linked and sulfo-glycomics by mass spectrometry. (Nix DB, Kumagai T, Katoh T, Tiemeyer M, Aoki K) J Vis Exp 2014 Nov 20(93):e51840       9 Citations
1Qrator: a web-based curation tool for glycan structures. (Eavenson M, Kochut KJ, Miller JA, Ranzinger R, Tiemeyer M, Aoki K, York WS) Glycobiology 2015 Jan;25(1):66-73       8 Citations
1Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I. (Mbua NE, Li X, Flanagan-Steet HR, Meng L, Aoki K, Moremen KW, Wolfert MA, Steet R, Boons GJ) Angew Chem Int Ed Engl 2013 Dec 02;52(49):13012-5       78 Citations
1In-gel β-elimination and aqueous-organic partition for improved O- and sulfoglycomics. (Kumagai T, Katoh T, Nix DB, Tiemeyer M, Aoki K) Anal Chem 2013 Sep 17;85(18):8692-9       34 Citations
1Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia. (Bakchoul T, Greinacher A, Sachs UJ, Krautwurst A, Renz H, Harb H, Bein G, Newman PJ, Santoso S) Blood 2013 Jul 18;122(3):321-7       43 Citations
1Stage-specific expression and antigenicity of glycoprotein glycans isolated from the human liver fluke, Opisthorchis viverrini. (Talabnin K, Aoki K, Saichua P, Wongkham S, Kaewkes S, Boons GJ, Sripa B, Tiemeyer M) Int J Parasitol 2013 Jan;43(1):37-50       18 Citations
1Porcine sperm bind to specific 6-sialylated biantennary glycans to form the oviduct reservoir. (Kadirvel G, Machado SA, Korneli C, Collins E, Miller P, Bess KN, Aoki K, Tiemeyer M, Bovin N, Miller DJ) Biol Reprod 2012 Jun;87(6):147       65 Citations
1Toll-like receptor 2 ligands promote microglial cell death by inducing autophagy. (Arroyo DS, Soria JA, Gaviglio EA, Garcia-Keller C, Cancela LM, Rodriguez-Galan MC, Wang JM, Iribarren P) FASEB J 2013 Jan;27(1):299-312       49 Citations
1Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis. (Nairn AV, Aoki K, dela Rosa M, Porterfield M, Lim JM, Kulik M, Pierce JM, Wells L, Dalton S, Tiemeyer M, Moremen KW) J Biol Chem 2012 Nov 02;287(45):37835-56       90 Citations
2The glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates. (Castonguay AC, Lasanajak Y, Song X, Olson LJ, Cummings RD, Smith DF, Dahms NM) Glycobiology 2012 Jul;22(7):983-96       20 Citations
1Preparation of a mannose-6-phosphate glycan microarray through fluorescent derivatization, phosphorylation, and immobilization of natural high-mannose N-glycans and application in ligand identification of P-type lectins. (Song X, Heimburg-Molinaro J, Dahms NM, Smith DF, Cummings RD) Methods Mol Biol 2012;808:137-48       12 Citations
1The role of lectins and glycans in platelet clearance. (Hoffmeister KM) J Thromb Haemost 2011 Jul;9 Suppl 1(0 1):35-43       71 Citations
2Mannose 6-phosphate receptor homology (MRH) domain-containing lectins in the secretory pathway. (Castonguay AC, Olson LJ, Dahms NM) Biochim Biophys Acta 2011 Sep;1810(9):815-26       32 Citations
1Effect of Thuja occidentalis and its polysaccharide on cell-mediated immune responses and cytokine levels of metastatic tumor-bearing animals. (Sunila ES, Hamsa TP, Kuttan G) Pharm Biol 2011 Oct;49(10):1065-73       32 Citations
1Glycomic analyses of mouse models of congenital muscular dystrophy. (Stalnaker SH, Aoki K, Lim JM, Porterfield M, Liu M, Satz JS, Buskirk S, Xiong Y, Zhang P, Campbell KP, Hu H, Live D, Tiemeyer M, Wells L) J Biol Chem 2011 Jun 17;286(24):21180-90       69 Citations
4Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling. (Gao C, Boylan B, Fang J, Wilcox DA, Newman DK, Newman PJ) Blood 2011 May 05;117(18):4946-52       120 Citations
1Sugar-free frosting, a homolog of SAD kinase, drives neural-specific glycan expression in the Drosophila embryo. (Baas S, Sharrow M, Kotu V, Middleton M, Nguyen K, Flanagan-Steet H, Aoki K, Tiemeyer M) Development 2011 Feb;138(3):553-63       21 Citations
1Uncovering genes and regulatory pathways related to urinary albumin excretion. (Hageman RS, Leduc MS, Caputo CR, Tsaih SW, Churchill GA, Korstanje R) J Am Soc Nephrol 2011 Jan;22(1):73-81       12 Citations
1The status of diagnostic markers for inflammatory bowel disease. (Beniwal P, Harrell L) Curr Gastroenterol Rep 2010 Dec;12(6):479-84       17 Citations
1The glycomics of glycan glucuronylation in Drosophila melanogaster. (Aoki K, Tiemeyer M) Methods Enzymol 2010;480:297-321       38 Citations
1A lectin affinity workflow targeting glycosite-specific, cancer-related carbohydrate structures in trypsin-digested human plasma. (Drake PM, Schilling B, Niles RK, Braten M, Johansen E, Liu H, Lerch M, Sorensen DJ, Li B, Allen S, Hall SC, Witkowska HE, Regnier FE, Gibson BW, Fisher SJ) Anal Biochem 2011 Jan 01;408(1):71-85       57 Citations
1Site mapping and characterization of O-glycan structures on alpha-dystroglycan isolated from rabbit skeletal muscle. (Stalnaker SH, Hashmi S, Lim JM, Aoki K, Porterfield M, Gutierrez-Sanchez G, Wheeler J, Ervasti JM, Bergmann C, Tiemeyer M, Wells L) J Biol Chem 2010 Aug 06;285(32):24882-91       87 Citations
1N-linked glycan at residue 523 of human parainfluenza virus type 3 hemagglutinin-neuraminidase masks a second receptor-binding site. (Mishin VP, Watanabe M, Taylor G, Devincenzo J, Bose M, Portner A, Alymova IV) J Virol 2010 Mar;84(6):3094-100       33 Citations
2Cation-independent mannose 6-phosphate receptor: a composite of distinct phosphomannosyl binding sites. (Bohnsack RN, Song X, Olson LJ, Kudo M, Gotschall RR, Canfield WM, Cummings RD, Smith DF, Dahms NM) J Biol Chem 2009 Dec 11;284(50):35215-26       64 Citations
2Glycan microarray analysis of P-type lectins reveals distinct phosphomannose glycan recognition. (Song X, Lasanajak Y, Olson LJ, Boonen M, Dahms NM, Kornfeld S, Cummings RD, Smith DF) J Biol Chem 2009 Dec 11;284(50):35201-14       61 Citations
2Gangliosides as high affinity receptors for tetanus neurotoxin. (Chen C, Fu Z, Kim JJ, Barbieri JT, Baldwin MR) J Biol Chem 2009 Sep 25;284(39):26569-77       115 Citations
1IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells. (Orlando R, Lim JM, Atwood JA 3rd, Angel PM, Fang M, Aoki K, Alvarez-Manilla G, Moremen KW, York WS, Tiemeyer M, Pierce M, Dalton S, Wells L) J Proteome Res 2009 Aug;8(8):3816-23       110 Citations
1Mapping glycans onto specific N-linked glycosylation sites of Pyrus communis PGIP redefines the interface for EPG-PGIP interactions. (Lim JM, Aoki K, Angel P, Garrison D, King D, Tiemeyer M, Bergmann C, Wells L) J Proteome Res 2009 Feb;8(2):673-80       20 Citations
1Glycans and glycosylation of platelets: current concepts and implications for transfusion. (Sørensen AL, Hoffmeister KM, Wandall HH) Curr Opin Hematol 2008 Nov;15(6):606-11       15 Citations
1The diversity of O-linked glycans expressed during Drosophila melanogaster development reflects stage- and tissue-specific requirements for cell signaling. (Aoki K, Porterfield M, Lee SS, Dong B, Nguyen K, McGlamry KH, Tiemeyer M) J Biol Chem 2008 Oct 31;283(44):30385-400       127 Citations
1Identification of N-glycosylated proteins from the central nervous system of Drosophila melanogaster. (Koles K, Lim JM, Aoki K, Porterfield M, Tiemeyer M, Wells L, Panin V) Glycobiology 2007 Dec;17(12):1388-403       85 Citations
1Heparin-induced thrombocytopenia associated with fondaparinux. (Warkentin TE, Maurer BT, Aster RH) N Engl J Med 2007 Jun 21;356(25):2653-5; discussion 2653-5       249 Citations
1Dynamic developmental elaboration of N-linked glycan complexity in the Drosophila melanogaster embryo. (Aoki K, Perlman M, Lim JM, Cantu R, Wells L, Tiemeyer M) J Biol Chem 2007 Mar 23;282(12):9127-42       239 Citations
1Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. (Gantner BN, Simmons RM, Underhill DM) EMBO J 2005 Mar 23;24(6):1277-86       570 Citations
1Identification and characterization of the unique N-linked glycan common to the flagellins and S-layer glycoprotein of Methanococcus voltae. (Voisin S, Houliston RS, Kelly J, Brisson JR, Watson D, Bardy SL, Jarrell KF, Logan SM) J Biol Chem 2005 Apr 29;280(17):16586-93       128 Citations
1Heparin is not required for detection of antibodies associated with heparin-induced thrombocytopenia/thrombosis. (Visentin GP, Moghaddam M, Beery SE, McFarland JG, Aster RH) J Lab Clin Med 2001 Jul;138(1):22-31       122 Citations
1Characterization and quantitation of wound matrix in the fetal rabbit. (DePalma RL, Krummel TM, Durham LA 3rd, Michna BA, Thomas BL, Nelson JM, Diegelmann RF) Matrix 1989 Jun;9(3):224-31       129 Citations
1Erythroid colony formation in cultures of mouse and human bone marrow: analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose-concanavalin A. (Iscove NN, Sieber F, Winterhalter KH) J Cell Physiol 1974 Apr;83(2):309-20       756 Citations