| 1 | Necessary Role of Ceramides in the Human Microvascular Endothelium During Health and Disease. (SenthilKumar G, Katunaric B, Zirgibel Z, Lindemer B, Jaramillo-Torres MJ, Bordas-Murphy H, Schulz ME, Pearson PJ, Freed JK) Circ Res 2024 Jan 05;134(1):81-96 12 Citations |
| 2 | S1P/S1PR1 signaling differentially regulates the allogeneic response of CD4 and CD8 T cells by modulating mitochondrial fission. (Tian L, Wu Y, Choi HJ, Sui X, Li X, Sofi MH, Kassir MF, Chen X, Mehrotra S, Ogretmen B, Yu XZ) Cell Mol Immunol 2022 Nov;19(11):1235-1250 31 Citations |
| 1 | Structural basis for receptor selectivity and inverse agonism in S1P5 receptors. (Lyapina E, Marin E, Gusach A, Orekhov P, Gerasimov A, Luginina A, Vakhrameev D, Ergasheva M, Kovaleva M, Khusainov G, Khorn P, Shevtsov M, Kovalev K, Bukhdruker S, Okhrimenko I, Popov P, Hu H, Weierstall U, Liu W, Cho Y, Gushchin I, Rogachev A, Bourenkov G, Park S, Park G, Hyun HJ, Park J, Gordeliy V, Borshchevskiy V, Mishin A, Cherezov V) Nat Commun 2022 Aug 12;13(1):4736 18 Citations |
| 1 | Sphinganine is associated with 24-h MAP in the non-sleepy with OSA. (Pak VM, Russell K, Shi Z, Zhang Q, Cox J, Uppal K, Yu T, Hertzberg V, Liu K, Ioachimescu OC, Collop N, Bliwise DL, Kutner NG, Rogers A, Dunbar SB) Metabolomics 2022 Apr 07;18(4):23 3 Citations |
| 5 | Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer. (Gupta P, Kadamberi IP, Mittal S, Tsaih SW, George J, Kumar S, Vijayan DK, Geethadevi A, Parashar D, Topchyan P, McAlarnen L, Volkman BF, Cui W, Zhang KYJ, Di Vizio D, Chaluvally-Raghavan P, Pradeep S) Adv Sci (Weinh) 2022 May;9(14):e2104452 63 Citations |
| 2 | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. (Liu S, Paknejad N, Zhu L, Kihara Y, Ray M, Chun J, Liu W, Hite RK, Huang XY) Nat Commun 2022 Feb 08;13(1):731 74 Citations |
| 1 | Investigations on T cell transmigration in a human skin-on-chip (SoC) model. (Ren X, Getschman AE, Hwang S, Volkman BF, Klonisch T, Levin D, Zhao M, Santos S, Liu S, Cheng J, Lin F) Lab Chip 2021 Apr 20;21(8):1527-1539 47 Citations |
| 1 | Manipulation of the Sphingolipid Rheostat Influences the Mediator of Flow-Induced Dilation in the Human Microvasculature. (Schulz ME, Katunaric B, Hockenberry JC, Gutterman DD, Freed JK) J Am Heart Assoc 2019 Sep 03;8(17):e013153 7 Citations |
| 1 | Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity. (Chakraborty P, Vaena SG, Thyagarajan K, Chatterjee S, Al-Khami A, Selvam SP, Nguyen H, Kang I, Wyatt MW, Baliga U, Hedley Z, Ngang RN, Guo B, Beeson GC, Husain S, Paulos CM, Beeson CC, Zilliox MJ, Hill EG, Mehrotra M, Yu XZ, Ogretmen B, Mehrotra S) Cell Rep 2019 Aug 13;28(7):1879-1893.e7 91 Citations |
| 6 | Acid ceramidase confers radioresistance to glioblastoma cells. (Doan NB, Nguyen HS, Al-Gizawiy MM, Mueller WM, Sabbadini RA, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP) Oncol Rep 2017 Oct;38(4):1932-1940 45 Citations |
| 1 | S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization. (Lee MH, Appleton KM, El-Shewy HM, Sorci-Thomas MG, Thomas MJ, Lopes-Virella MF, Luttrell LM, Hammad SM, Klein RL) J Lipid Res 2017 Feb;58(2):325-338 42 Citations |
| 1 | Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. (Wang R, Ding Q, De Assuncao TM, Mounajjed T, Maiers JL, Dou C, Cao S, Yaqoob U, Huebert RC, Shah VH) Am J Pathol 2017 Jan;187(1):134-145 6 Citations |
| 1 | Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration. (Wang R, Ding Q, Yaqoob U, de Assuncao TM, Verma VK, Hirsova P, Cao S, Mukhopadhyay D, Huebert RC, Shah VH) J Biol Chem 2015 Dec 25;290(52):30684-96 209 Citations |
| 4 | Ceramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation. (Freed JK, Beyer AM, LoGiudice JA, Hockenberry JC, Gutterman DD) Circ Res 2014 Aug 15;115(5):525-32 121 Citations |
| 4 | New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. (de Assuncao TM, Lomberk G, Cao S, Yaqoob U, Mathison A, Simonetto DA, Huebert RC, Urrutia RA, Shah VH) J Biol Chem 2014 May 30;289(22):15798-809 47 Citations |
| 1 | Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. (Liu M, Seo J, Allegood J, Bi X, Zhu X, Boudyguina E, Gebre AK, Avni D, Shah D, Sorci-Thomas MG, Thomas MJ, Shelness GS, Spiegel S, Parks JS) J Biol Chem 2014 Jan 31;289(5):2801-14 70 Citations |
| 1 | High density lipoprotein biogenesis, cholesterol efflux, and immune cell function. (Sorci-Thomas MG, Thomas MJ) Arterioscler Thromb Vasc Biol 2012 Nov;32(11):2561-5 97 Citations |
| 1 | Extracellular matrix molecules regulate endothelial cell migration stimulated by lysophosphatidic acid. (Panetti TS, Hannah DF, Avraamides C, Gaughan JP, Marcinkiewicz C, Huttenlocher A, Mosher DF) J Thromb Haemost 2004 Sep;2(9):1645-56 37 Citations |
| 1 | Ceramide reduces endothelium-dependent vasodilation by increasing superoxide production in small bovine coronary arteries. (Zhang DX, Zou AP, Li PL) Circ Res 2001 Apr 27;88(8):824-31 73 Citations |
| 2 | Effect of ceramide on KCa channel activity and vascular tone in coronary arteries. (Li PL, Zhang DX, Zou AP, Campbell WB) Hypertension 1999 Jun;33(6):1441-6 48 Citations |
| 1 | An accessory role for ceramide in interleukin-1beta induced prostaglandin synthesis. (Kirtikara K, Laulederkind SJ, Raghow R, Kanekura T, Ballou LR) Mol Cell Biochem 1998 Apr;181(1-2):41-8 21 Citations |
| 1 | Protein kinase A induces phosphorylation of the human 5-HT1A receptor and augments its desensitization by protein kinase C in CHO-K1 cells. (Raymond JR, Olsen CL) Biochemistry 1994 Sep 20;33(37):11264-9 26 Citations |
| 1 | Sphingosine-mediated phosphatidylinositol metabolism and calcium mobilization. (Chao CP, Laulederkind SJ, Ballou LR) J Biol Chem 1994 Feb 25;269(8):5849-56 88 Citations |
| 1 | Protein kinase C induces phosphorylation and desensitization of the human 5-HT1A receptor. (Raymond JR) J Biol Chem 1991 Aug 05;266(22):14747-53 111 Citations |
