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Publications indexed to the term Protein Engineering

1Evolution of fold switching in a metamorphic protein. (Dishman AF, Tyler RC, Fox JC, Kleist AB, Prehoda KE, Babu MM, Peterson FC, Volkman BF) Science 2021 01 01;371(6524):86-90       2 Citations
1Natural and engineered chemokine (C-X-C motif) receptor 4 agonists prevent acute respiratory distress syndrome after lung ischemia-reperfusion injury and hemorrhage. (Babu FS, Liang X, Enten GA, DeSantis AJ, Volkman BF, Gao X, Majetschak M) Sci Rep 2020 07 09;10(1):11359       1 Citation
1TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome. (Olsen RHJ, DiBerto JF, English JG, Glaudin AM, Krumm BE, Slocum ST, Che T, Gavin AC, McCorvy JD, Roth BL, Strachan RT) Nat Chem Biol 2020 08;16(8):841-849       15 Citations
1Unfolding the Mysteries of Protein Metamorphosis. (Dishman AF, Volkman BF) ACS Chem Biol 2018 06 15;13(6):1438-1446       21 Citations
2Production of Recombinant Chemokines and Validation of Refolding. (Veldkamp CT, Koplinski CA, Jensen DR, Peterson FC, Smits KM, Smith BL, Johnson SK, Lettieri C, Buchholz WG, Solheim JC, Volkman BF) Methods Enzymol 2016;570:539-65       13 Citations
2Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-Inhibitory Dimer Conformation. (Fox JC, Tyler RC, Guzzo C, Tuinstra RL, Peterson FC, Lusso P, Volkman BF) ACS Chem Biol 2015 Nov 20;10(11):2580-8       18 Citations
1Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes. (Scaife M, Pacienza N, Au BC, Wang JC, Devine S, Scheid E, Lee CJ, Lopez-Perez O, Neschadim A, Fowler DH, Foley R, Medin JA) Gene Ther 2013 Jan;20(1):24-34       12 Citations
1Thrombomodulin is required for the antithrombotic activity of thrombin mutant W215A/E217A in a mouse model of arterial thrombosis. (Vicente CP, Weiler H, Di Cera E, Tollefsen DM) Thromb Res 2012 Oct;130(4):646-8       7 Citations
1Hemophilia: an amazing 35-year journey from the depths of HIV to the threshold of cure. (White GC) Trans Am Clin Climatol Assoc 2010;121:61-73; discussion 74-5       14 Citations
1Generation of gene-specific mutated rats using zinc-finger nucleases. (Geurts AM, Cost GJ, Rémy S, Cui X, Tesson L, Usal C, Ménoret S, Jacob HJ, Anegon I, Buelow R) Methods Mol Biol 2010;597:211-25       81 Citations
1A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes. (Scheuplein F, Rissiek B, Driver JP, Chen YG, Koch-Nolte F, Serreze DV) J Autoimmun 2010 Mar;34(2):145-54       24 Citations
2Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. (Kerschen EJ, Fernandez JA, Cooley BC, Yang XV, Sood R, Mosnier LO, Castellino FJ, Mackman N, Griffin JH, Weiler H) J Exp Med 2007 Oct 01;204(10):2439-48       245 Citations
2An engineered second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like conformation with XCR1 agonist activity. (Tuinstra RL, Peterson FC, Elgin ES, Pelzek AJ, Volkman BF) Biochemistry 2007 Mar 13;46(10):2564-73       37 Citations
1Improved "optical highlighter" probes derived from discosoma red fluorescent protein. (Robinson LC, Marchant JS) Biophys J 2005 Feb;88(2):1444-57       10 Citations
1Characterization of the heptad repeat regions, HR1 and HR2, and design of a fusion core structure model of the spike protein from severe acute respiratory syndrome (SARS) coronavirus. (Xu Y, Zhu J, Liu Y, Lou Z, Yuan F, Liu Y, Cole DK, Ni L, Su N, Qin L, Li X, Bai Z, Bell JI, Pang H, Tien P, Gao GF, Rao Z) Biochemistry 2004 Nov 09;43(44):14064-71       37 Citations
1Production of knockout rats using ENU mutagenesis and a yeast-based screening assay. (Zan Y, Haag JD, Chen KS, Shepel LA, Wigington D, Wang YR, Hu R, Lopez-Guajardo CC, Brose HL, Porter KI, Leonard RA, Hitt AA, Schommer SL, Elegbede AF, Gould MN) Nat Biotechnol 2003 Jun;21(6):645-51       177 Citations
1A polar, solvent-exposed residue can be essential for native protein structure. (Hill RB, DeGrado WF) Structure 2000 May 15;8(5):471-9       37 Citations
1Role of tryptophan 26 in the NAD glycohydrolase reaction of the S-1 subunit of pertussis toxin. (Cortina G, Barbieri JT) J Biol Chem 1989 Oct 15;264(29):17322-8       12 Citations