| 1 | Effect of Mimic Hypoxia on the Proliferation and Expression of miR-27a, miR-9, miR-370 and their Target Genes in MOLT-4 and KG1a Cell Lines. (Emaogolizadeh Gurd Tapeh B, Mohammadi A, Alivand MR, Solali S) Asian Pac J Cancer Prev 2021 Jun 01;22(6):1975-1984 1 Citation |
| 1 | Myoglobin promotes nitrite-dependent mitochondrial S-nitrosation to mediate cytoprotection after hypoxia/reoxygenation. (Quesnelle K, Guimaraes DA, Rao K, Singh AB, Wang Y, Hogg N, Shiva S) Nitric Oxide 2020 Nov 01;104-105:36-43 5 Citations |
| 2 | Divergent mutational processes distinguish hypoxic and normoxic tumours. (Bhandari V, Li CH, Bristow RG, Boutros PC, PCAWG Consortium) Nat Commun 2020 Feb 05;11(1):737 114 Citations |
| 2 | Prophylactic supplementation of 20-HETE ameliorates hypoxia/reoxygenation injury in pulmonary vascular endothelial cells by inhibiting apoptosis. (Sugumaran P, Narayanan V, Zhu D, Medhora M, Jacobs ER, Chandramohan Y, Selvaraj V, Dhanasekaran A) Acta Histochem 2020 Jan;122(1):151461 12 Citations |
| 1 | An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium. (Yang H, Qin X, Wang H, Zhao X, Liu Y, Wo HT, Liu C, Nishiga M, Chen H, Ge J, Sayed N, Abilez OJ, Ding D, Heilshorn SC, Li K) ACS Nano 2019 Sep 24;13(9):9880-9894 127 Citations |
| 1 | Attenuation of cardiac ischemia-reperfusion injury by sodium thiosulfate is partially dependent on the effect of cystathione beta synthase in the myocardium. (Kannan S, Boovarahan SR, Rengaraju J, Prem P, Kurian GA) Cell Biochem Biophys 2019 Sep;77(3):261-272 19 Citations |
| 2 | Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice. (Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL) JCI Insight 2018 Oct 04;3(19) 67 Citations |
| 1 | Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism. (Benej M, Hong X, Vibhute S, Scott S, Wu J, Graves E, Le QT, Koong AC, Giaccia AJ, Yu B, Chen CS, Papandreou I, Denko NC) Proc Natl Acad Sci U S A 2018 Oct 16;115(42):10756-10761 147 Citations |
| 1 | Regulation of Cerebral Blood Flow: Response to Cytochrome P450 Lipid Metabolites. (Harder DR, Rarick KR, Gebremedhin D, Cohen SS) Compr Physiol 2018 Mar 25;8(2):801-821 6 Citations |
| 1 | A method for the long-term cultivation of mammalian cells in the absence of oxygen: Characterization of cell replication, hypoxia-inducible factor expression and reactive oxygen species production. (Plotkin BJ, Davis JW, Strizzi L, Lee P, Christoffersen-Cebi J, Kacmar J, Rivero OJ, Elsayed N, Zanghi N, Ito B, Sigar IM) Tissue Cell 2018 Feb;50:59-68 6 Citations |
| 1 | Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP). (Mitamura T, Pradeep S, McGuire M, Wu SY, Ma S, Hatakeyama H, Lyons YA, Hisamatsu T, Noh K, Villar-Prados A, Chen X, Ivan C, Rodriguez-Aguayo C, Hu W, Lopez-Berestein G, Coleman RL, Sood AK) Oncogene 2018 Feb 08;37(6):722-731 43 Citations |
| 3 | Twist1 in Hypoxia-induced Pulmonary Hypertension through Transforming Growth Factor-β-Smad Signaling. (Mammoto T, Muyleart M, Konduri GG, Mammoto A) Am J Respir Cell Mol Biol 2018 Feb;58(2):194-207 85 Citations |
| 1 | Development of insulin resistance through sprouting of inflammatory markers during hypoxia in 3T3-L1 adipocytes and amelioration with curcumin. (Priyanka A, Shyni GL, Anupama N, Raj PS, Anusree SS, Raghu KG) Eur J Pharmacol 2017 Oct 05;812:73-81 22 Citations |
| 3 | Identity and function of a cardiac mitochondrial small conductance Ca2+-activated K+ channel splice variant. (Yang M, Camara AKS, Aldakkak M, Kwok WM, Stowe DF) Biochim Biophys Acta Bioenerg 2017 Jun;1858(6):442-458 31 Citations |
| 1 | Novel Epigenetic Controlling of Hypoxia Pathway Related to Overexpression and Promoter Hypomethylation of TET1 and TET2 in RPE Cells. (Alivand MR, Soheili ZS, Pornour M, Solali S, Sabouni F) J Cell Biochem 2017 Oct;118(10):3193-3204 25 Citations |
| 1 | Upregulation of 20-HETE Synthetic Cytochrome P450 Isoforms by Oxygen-Glucose Deprivation in Cortical Neurons. (Zhang H, Falck JR, Roman RJ, Harder DR, Koehler RC, Yang ZJ) Cell Mol Neurobiol 2017 Oct;37(7):1279-1286 13 Citations |
| 1 | Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation. (Zhang Y, Hong G, Lee KS, Hammock BD, Gebremedhin D, Harder DR, Koehler RC, Sapirstein A) J Neurochem 2017 Mar;140(5):814-825 25 Citations |
| 1 | FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. (Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK) J Clin Invest 2016 May 02;126(5):1885-96 114 Citations |
| 1 | Involvement of gap junctions between smooth muscle cells in sustained hypoxic pulmonary vasoconstriction development: a potential role for 15-HETE and 20-HETE. (Kizub IV, Lakhkar A, Dhagia V, Joshi SR, Jiang H, Wolin MS, Falck JR, Koduru SR, Errabelli R, Jacobs ER, Schwartzman ML, Gupte SA) Am J Physiol Lung Cell Mol Physiol 2016 Apr 15;310(8):L772-83 18 Citations |
| 1 | Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. (Rupaimoole R, Ivan C, Yang D, Gharpure KM, Wu SY, Pecot CV, Previs RA, Nagaraja AS, Armaiz-Pena GN, McGuire M, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Zhang W, Lopez-Berestein G, Calin GA, Sood AK) Oncogene 2016 Aug 18;35(33):4312-20 84 Citations |
| 2 | Thrombopoietin receptor agonists protect human cardiac myocytes from injury by activation of cell survival pathways. (Baker JE, Su J, Koprowski S, Dhanasekaran A, Aufderheide TP, Gross GJ) J Pharmacol Exp Ther 2015 Mar;352(3):429-37 12 Citations |
| 1 | Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. (Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK) Nat Commun 2014 Oct 29;5:5202 159 Citations |
| 1 | Erythropoietin protects cardiomyocytes from cell death during hypoxia/reperfusion injury through activation of survival signaling pathways. (Parvin A, Pranap R, Shalini U, Devendran A, Baker JE, Dhanasekaran A) PLoS One 2014;9(9):e107453 29 Citations |
| 2 | In vivo detection of hyperoxia-induced pulmonary endothelial cell death using (99m)Tc-duramycin. (Audi SH, Jacobs ER, Zhao M, Roerig DL, Haworth ST, Clough AV) Nucl Med Biol 2015 Jan;42(1):46-52 32 Citations |
| 1 | Melatonin suppresses hypoxia-induced migration of HUVECs via inhibition of ERK/Rac1 activation. (Yang L, Zheng J, Xu R, Zhang Y, Gu L, Dong J, Zhu Y, Zhou R, Zheng L, Zhang X, Du J) Int J Mol Sci 2014 Aug 13;15(8):14102-21 29 Citations |
| 1 | Oxidative stress induced mitochondrial protein kinase A mediates cytochrome c oxidase dysfunction. (Srinivasan S, Spear J, Chandran K, Joseph J, Kalyanaraman B, Avadhani NG) PLoS One 2013;8(10):e77129 56 Citations |
| 1 | Mechanistic insights into self-reinforcing processes driving abnormal histogenesis during the development of pancreatic cancer. (Iovanna JL, Marks DL, Fernandez-Zapico ME, Urrutia R) Am J Pathol 2013 Apr;182(4):1078-86 16 Citations |
| 1 | Measuring tumor cycling hypoxia and angiogenesis using a side-firing fiber optic probe. (Yu B, Shah A, Wang B, Rajaram N, Wang Q, Ramanujam N, Palmer GM, Dewhirst MW) J Biophotonics 2014 Jul;7(7):552-64 17 Citations |
| 2 | Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death. (Hamidi T, Cano CE, Grasso D, Garcia MN, Sandi MJ, Calvo EL, Dagorn JC, Lomberk G, Urrutia R, Goruppi S, Carracedo A, Velasco G, Iovanna JL) Clin Cancer Res 2012 Oct 01;18(19):5234-46 65 Citations |
| 2 | LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. (Mammoto T, Chen J, Jiang E, Jiang A, Smith LE, Ingber DE, Mammoto A) PLoS One 2012;7(7):e41596 32 Citations |
| 1 | Dopaminergic-like cells from epigenetically reprogrammed mesenchymal stem cells. (Zhang Z, Alexanian AR) J Cell Mol Med 2012 Nov;16(11):2708-14 12 Citations |
| 1 | Anti-inflammatory properties of histone deacetylase inhibitors: a mechanistic study. (Chong W, Li Y, Liu B, Liu Z, Zhao T, Wonsey DR, Chen C, Velmahos GC, deMoya MA, King DR, Kung AL, Alam HB) J Trauma Acute Care Surg 2012 Feb;72(2):347-53; discussion 353-4 28 Citations |
| 3 | Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures. (Renic M, Kumar SN, Gebremedhin D, Florence MA, Gerges NZ, Falck JR, Harder DR, Roman RJ) Am J Physiol Heart Circ Physiol 2012 Mar 15;302(6):H1285-93 32 Citations |
| 1 | The mitochondrial bioenergetic phenotype for protection from cardiac ischemia in SUR2 mutant mice. (Aggarwal NT, Pravdic D, McNally EM, Bosnjak ZJ, Shi NQ, Makielski JC) Am J Physiol Heart Circ Physiol 2010 Dec;299(6):H1884-90 12 Citations |
| 1 | Role of mitochondrial reactive oxygen species in osteoclast differentiation. (Srinivasan S, Koenigstein A, Joseph J, Sun L, Kalyanaraman B, Zaidi M, Avadhani NG) Ann N Y Acad Sci 2010 Mar;1192(1):245-52 118 Citations |
| 2 | 20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells. (Dhanasekaran A, Bodiga S, Gruenloh S, Gao Y, Dunn L, Falck JR, Buonaccorsi JN, Medhora M, Jacobs ER) Am J Physiol Heart Circ Physiol 2009 Mar;296(3):H777-86 45 Citations |
| 2 | Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross. (Kunert MP, Dwinell MR, Drenjancevic Peric I, Lombard JH) Am J Physiol Regul Integr Comp Physiol 2008 Aug;295(2):R516-27 11 Citations |
| 1 | Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha. (Chung C, Doll JA, Stellmach VM, Gonzales J, Surapureddi S, Cornwell M, Reddy JK, Crawford SE) Adv Exp Med Biol 2008;617:591-7 26 Citations |
| 2 | Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia. (Dhanasekaran A, Gruenloh SK, Buonaccorsi JN, Zhang R, Gross GJ, Falck JR, Patel PK, Jacobs ER, Medhora M) Am J Physiol Heart Circ Physiol 2008 Feb;294(2):H724-35 165 Citations |
| 1 | Role of 20-HETE in the hypoxia-induced activation of Ca2+-activated K+ channel currents in rat cerebral arterial muscle cells. (Gebremedhin D, Yamaura K, Harder DR) Am J Physiol Heart Circ Physiol 2008 Jan;294(1):H107-20 53 Citations |
| 1 | ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts. (Grobe JL, Der Sarkissian S, Stewart JM, Meszaros JG, Raizada MK, Katovich MJ) Clin Sci (Lond) 2007 Oct;113(8):357-64 77 Citations |
| 2 | Isoflurane preconditioning uncouples mitochondria and protects against hypoxia-reoxygenation. (Ljubkovic M, Mio Y, Marinovic J, Stadnicka A, Warltier DC, Bosnjak ZJ, Bienengraeber M) Am J Physiol Cell Physiol 2007 May;292(5):C1583-90 75 Citations |
| 2 | Contribution of epoxyeicosatrienoic acids to the hypoxia-induced activation of Ca2+ -activated K+ channel current in cultured rat hippocampal astrocytes. (Yamaura K, Gebremedhin D, Zhang C, Narayanan J, Hoefert K, Jacobs ER, Koehler RC, Harder DR) Neuroscience 2006 Dec;143(3):703-16 46 Citations |
| 1 | Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation. (Gladwin MT, Raat NJ, Shiva S, Dezfulian C, Hogg N, Kim-Shapiro DB, Patel RP) Am J Physiol Heart Circ Physiol 2006 Nov;291(5):H2026-35 297 Citations |
| 1 | A novel mechanism for regulation of retinal blood flow by lactate: gap junctions, hypoxia, and pericytes. (Lombard JH) Am J Physiol Heart Circ Physiol 2006 Mar;290(3):H921-2 10 Citations |
| 1 | Steroidogenesis in human aldosterone-secreting adenomas and adrenal hyperplasias: effects of hypoxia in vitro. (Raff H, Bruder ED, St. Luke's Medical Center Adrenal Tumor Study Group) Am J Physiol Endocrinol Metab 2006 Jan;290(1):E199-E203 10 Citations |
| 1 | Modeling prostate cancer: in regards to Nahum et al. (Int J Radiat Oncol Biol Phys 2003;57:391-401). (Wang JZ, Mayr NA, Li XA, Stewart RD) Int J Radiat Oncol Biol Phys 2005 Jan 01;61(1):309-10; author reply 310-1 4 Citations |
| 4 | Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries. (Zhu D, Medhora M, Campbell WB, Spitzbarth N, Baker JE, Jacobs ER) Circ Res 2003 May 16;92(9):992-1000 143 Citations |
| 1 | Functional activation of heat shock factor and hypoxia-inducible factor in the kidney. (Eickelberg O, Seebach F, Riordan M, Thulin G, Mann A, Reidy KH, Van Why SK, Kashgarian M, Siegel N) J Am Soc Nephrol 2002 Aug;13(8):2094-101 57 Citations |
| 1 | Oxygen-dependent expression of hypoxia-inducible factor-1alpha in renal medullary cells of rats. (Zou AP, Yang ZZ, Li PL, Cowley AW JR) Physiol Genomics 2001 Aug 28;6(3):159-68 52 Citations |
| 1 | HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation. (Yu F, White SB, Zhao Q, Lee FS) Proc Natl Acad Sci U S A 2001 Aug 14;98(17):9630-5 743 Citations |
| 1 | Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein. (Yu F, White SB, Zhao Q, Lee FS) Cancer Res 2001 May 15;61(10):4136-42 82 Citations |
| 1 | Ion exchange activity in pulmonary artery smooth muscle cells: the response to hypoxia. (Madden JA, Ray DE, Keller PA, Kleinman JG) Am J Physiol Lung Cell Mol Physiol 2001 Feb;280(2):L264-71 35 Citations |
| 2 | Increased mitochondrial K(ATP) channel activity during chronic myocardial hypoxia: is cardioprotection mediated by improved bioenergetics? (Eells JT, Henry MM, Gross GJ, Baker JE) Circ Res 2000 Nov 10;87(10):915-21 65 Citations |
| 1 | Understanding the temporal relationship of ATP loss, calcium loading, and rigor contracture during anoxia, and hypercontracture after anoxia in cardiac myocytes. (Stowe DF) Cardiovasc Res 1999 Aug 01;43(2):285-7 3 Citations |
| 1 | Augmented endothelium-dependent constriction to hypoxia early and late following reperfusion of the canine coronary artery. (Pearson PJ, Lin PJ, Schaff HV, Vanhoutte PM) Clin Exp Pharmacol Physiol 1996 Aug;23(8):634-41 31 Citations |
| 1 | Correlation of radiobiological assays of hypoxic fraction with phosphorus-31 magnetic resonance spectroscopy across multiple tumor lines. (Li SJ, Jin GY, Fish BL, Moulder JE) Radiat Res 1995 Jul;143(1):45-53 10 Citations |
| 2 | Hypoxia increases the activity of Ca(2+)-sensitive K+ channels in cat cerebral arterial muscle cell membranes. (Gebremedhin D, Bonnet P, Greene AS, England SK, Rusch NJ, Lombard JH, Harder DR) Pflugers Arch 1994 Oct;428(5-6):621-30 99 Citations |
| 1 | Effect of hypoxia and norepinephrine on cytoplasmic free Ca2+ in pulmonary and cerebral arterial myocytes. (Vadula MS, Kleinman JG, Madden JA) Am J Physiol 1993 Dec;265(6 Pt 1):L591-7 113 Citations |
| 1 | Vasoconstriction to hypoxia of the human internal mammary artery. (Lin PJ, Pearson PJ, Schaff HV) Changgeng Yi Xue Za Zhi 1991 Sep;14(3):141-8 |
| 1 | Prediction of tumor radiosensitivity by hexafluoromisonidazole retention monitored by [1H]/[19F] magnetic resonance spectroscopy. (Li SJ, Jin GY, Moulder JE) Cancer Commun 1991 May;3(5):133-9 17 Citations |
| 1 | Effects of hypoxia on a potassium channel in cat cerebral arterial muscle cells. (Bonnet P, Gebremedhin D, Rush NJ, Harder DR) Z Kardiol 1991;80 Suppl 7:25-7 13 Citations |
| 1 | Dynamic measurements of hexafluoromisonidazole (CCI-103F) retention in mouse tumours by 1H/19F magnetic resonance spectroscopy. (Jin GY, Li SJ, Moulder JE, Raleigh JA) Int J Radiat Biol 1990 Dec;58(6):1025-34 26 Citations |