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| 1 | Myoglobin promotes nitrite-dependent mitochondrial S-nitrosation to mediate cytoprotection after hypoxia/reoxygenation. (Quesnelle K, Guimaraes DA, Rao K, Singh AB, Wang Y, Hogg N, Shiva S) Nitric Oxide 2020 Nov 01;104-105:36-43 5 Citations |
| 2 | Divergent mutational processes distinguish hypoxic and normoxic tumours. (Bhandari V, Li CH, Bristow RG, Boutros PC, PCAWG Consortium) Nat Commun 2020 Feb 05;11(1):737 108 Citations |
| 1 | An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium. (Yang H, Qin X, Wang H, Zhao X, Liu Y, Wo HT, Liu C, Nishiga M, Chen H, Ge J, Sayed N, Abilez OJ, Ding D, Heilshorn SC, Li K) ACS Nano 2019 Sep 24;13(9):9880-9894 120 Citations |
| 1 | Attenuation of cardiac ischemia-reperfusion injury by sodium thiosulfate is partially dependent on the effect of cystathione beta synthase in the myocardium. (Kannan S, Boovarahan SR, Rengaraju J, Prem P, Kurian GA) Cell Biochem Biophys 2019 Sep;77(3):261-272 17 Citations |
| 2 | Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice. (Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL) JCI Insight 2018 Oct 04;3(19) 63 Citations |
| 1 | Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism. (Benej M, Hong X, Vibhute S, Scott S, Wu J, Graves E, Le QT, Koong AC, Giaccia AJ, Yu B, Chen CS, Papandreou I, Denko NC) Proc Natl Acad Sci U S A 2018 Oct 16;115(42):10756-10761 140 Citations |
| 1 | Regulation of Cerebral Blood Flow: Response to Cytochrome P450 Lipid Metabolites. (Harder DR, Rarick KR, Gebremedhin D, Cohen SS) Compr Physiol 2018 Mar 25;8(2):801-821 5 Citations |
| 1 | A method for the long-term cultivation of mammalian cells in the absence of oxygen: Characterization of cell replication, hypoxia-inducible factor expression and reactive oxygen species production. (Plotkin BJ, Davis JW, Strizzi L, Lee P, Christoffersen-Cebi J, Kacmar J, Rivero OJ, Elsayed N, Zanghi N, Ito B, Sigar IM) Tissue Cell 2018 Feb;50:59-68 6 Citations |
| 1 | Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP). (Mitamura T, Pradeep S, McGuire M, Wu SY, Ma S, Hatakeyama H, Lyons YA, Hisamatsu T, Noh K, Villar-Prados A, Chen X, Ivan C, Rodriguez-Aguayo C, Hu W, Lopez-Berestein G, Coleman RL, Sood AK) Oncogene 2018 Feb 08;37(6):722-731 41 Citations |
| 3 | Twist1 in Hypoxia-induced Pulmonary Hypertension through Transforming Growth Factor-β-Smad Signaling. (Mammoto T, Muyleart M, Konduri GG, Mammoto A) Am J Respir Cell Mol Biol 2018 Feb;58(2):194-207 80 Citations |
| 1 | Development of insulin resistance through sprouting of inflammatory markers during hypoxia in 3T3-L1 adipocytes and amelioration with curcumin. (Priyanka A, Shyni GL, Anupama N, Raj PS, Anusree SS, Raghu KG) Eur J Pharmacol 2017 Oct 05;812:73-81 20 Citations |
| 2 | Identity and function of a cardiac mitochondrial small conductance Ca2+-activated K+ channel splice variant. (Yang M, Camara AKS, Aldakkak M, Kwok WM, Stowe DF) Biochim Biophys Acta Bioenerg 2017 Jun;1858(6):442-458 30 Citations |
| 1 | Novel Epigenetic Controlling of Hypoxia Pathway Related to Overexpression and Promoter Hypomethylation of TET1 and TET2 in RPE Cells. (Alivand MR, Soheili ZS, Pornour M, Solali S, Sabouni F) J Cell Biochem 2017 Oct;118(10):3193-3204 25 Citations |
| 1 | FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. (Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK) J Clin Invest 2016 May 02;126(5):1885-96 109 Citations |
| 1 | Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression. (Rupaimoole R, Ivan C, Yang D, Gharpure KM, Wu SY, Pecot CV, Previs RA, Nagaraja AS, Armaiz-Pena GN, McGuire M, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Zhang W, Lopez-Berestein G, Calin GA, Sood AK) Oncogene 2016 Aug 18;35(33):4312-20 84 Citations |
| 2 | Thrombopoietin receptor agonists protect human cardiac myocytes from injury by activation of cell survival pathways. (Baker JE, Su J, Koprowski S, Dhanasekaran A, Aufderheide TP, Gross GJ) J Pharmacol Exp Ther 2015 Mar;352(3):429-37 11 Citations |
| 1 | Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. (Rupaimoole R, Wu SY, Pradeep S, Ivan C, Pecot CV, Gharpure KM, Nagaraja AS, Armaiz-Pena GN, McGuire M, Zand B, Dalton HJ, Filant J, Miller JB, Lu C, Sadaoui NC, Mangala LS, Taylor M, van den Beucken T, Koch E, Rodriguez-Aguayo C, Huang L, Bar-Eli M, Wouters BG, Radovich M, Ivan M, Calin GA, Zhang W, Lopez-Berestein G, Sood AK) Nat Commun 2014 Oct 29;5:5202 158 Citations |
| 1 | Erythropoietin protects cardiomyocytes from cell death during hypoxia/reperfusion injury through activation of survival signaling pathways. (Parvin A, Pranap R, Shalini U, Devendran A, Baker JE, Dhanasekaran A) PLoS One 2014;9(9):e107453 28 Citations |
| 1 | In vivo detection of hyperoxia-induced pulmonary endothelial cell death using (99m)Tc-duramycin. (Audi SH, Jacobs ER, Zhao M, Roerig DL, Haworth ST, Clough AV) Nucl Med Biol 2015 Jan;42(1):46-52 31 Citations |
| 1 | Melatonin suppresses hypoxia-induced migration of HUVECs via inhibition of ERK/Rac1 activation. (Yang L, Zheng J, Xu R, Zhang Y, Gu L, Dong J, Zhu Y, Zhou R, Zheng L, Zhang X, Du J) Int J Mol Sci 2014 Aug 13;15(8):14102-21 28 Citations |
| 1 | Oxidative stress induced mitochondrial protein kinase A mediates cytochrome c oxidase dysfunction. (Srinivasan S, Spear J, Chandran K, Joseph J, Kalyanaraman B, Avadhani NG) PLoS One 2013;8(10):e77129 56 Citations |
| 1 | Mechanistic insights into self-reinforcing processes driving abnormal histogenesis during the development of pancreatic cancer. (Iovanna JL, Marks DL, Fernandez-Zapico ME, Urrutia R) Am J Pathol 2013 Apr;182(4):1078-86 16 Citations |
| 1 | Measuring tumor cycling hypoxia and angiogenesis using a side-firing fiber optic probe. (Yu B, Shah A, Wang B, Rajaram N, Wang Q, Ramanujam N, Palmer GM, Dewhirst MW) J Biophotonics 2014 Jul;7(7):552-64 17 Citations |
| 2 | Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death. (Hamidi T, Cano CE, Grasso D, Garcia MN, Sandi MJ, Calvo EL, Dagorn JC, Lomberk G, Urrutia R, Goruppi S, Carracedo A, Velasco G, Iovanna JL) Clin Cancer Res 2012 Oct 01;18(19):5234-46 64 Citations |
| 2 | LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. (Mammoto T, Chen J, Jiang E, Jiang A, Smith LE, Ingber DE, Mammoto A) PLoS One 2012;7(7):e41596 32 Citations |
| 1 | Dopaminergic-like cells from epigenetically reprogrammed mesenchymal stem cells. (Zhang Z, Alexanian AR) J Cell Mol Med 2012 Nov;16(11):2708-14 12 Citations |
| 1 | Anti-inflammatory properties of histone deacetylase inhibitors: a mechanistic study. (Chong W, Li Y, Liu B, Liu Z, Zhao T, Wonsey DR, Chen C, Velmahos GC, deMoya MA, King DR, Kung AL, Alam HB) J Trauma Acute Care Surg 2012 Feb;72(2):347-53; discussion 353-4 28 Citations |
| 2 | Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures. (Renic M, Kumar SN, Gebremedhin D, Florence MA, Gerges NZ, Falck JR, Harder DR, Roman RJ) Am J Physiol Heart Circ Physiol 2012 Mar 15;302(6):H1285-93 31 Citations |
| 1 | Role of mitochondrial reactive oxygen species in osteoclast differentiation. (Srinivasan S, Koenigstein A, Joseph J, Sun L, Kalyanaraman B, Zaidi M, Avadhani NG) Ann N Y Acad Sci 2010 Mar;1192(1):245-52 115 Citations |
| 1 | Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross. (Kunert MP, Dwinell MR, Drenjancevic Peric I, Lombard JH) Am J Physiol Regul Integr Comp Physiol 2008 Aug;295(2):R516-27 11 Citations |
| 1 | Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha. (Chung C, Doll JA, Stellmach VM, Gonzales J, Surapureddi S, Cornwell M, Reddy JK, Crawford SE) Adv Exp Med Biol 2008;617:591-7 25 Citations |
| 1 | The cardioprotective effect of mesenchymal stem cells is mediated by IGF-I and VEGF. (Sadat S, Gehmert S, Song YH, Yen Y, Bai X, Gaiser S, Klein H, Alt E) Biochem Biophys Res Commun 2007 Nov 23;363(3):674-9 290 Citations |
| 1 | ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts. (Grobe JL, Der Sarkissian S, Stewart JM, Meszaros JG, Raizada MK, Katovich MJ) Clin Sci (Lond) 2007 Oct;113(8):357-64 76 Citations |
| 1 | Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation. (Gladwin MT, Raat NJ, Shiva S, Dezfulian C, Hogg N, Kim-Shapiro DB, Patel RP) Am J Physiol Heart Circ Physiol 2006 Nov;291(5):H2026-35 294 Citations |
| 1 | Steroidogenesis in human aldosterone-secreting adenomas and adrenal hyperplasias: effects of hypoxia in vitro. (Raff H, Bruder ED, St. Luke's Medical Center Adrenal Tumor Study Group) Am J Physiol Endocrinol Metab 2006 Jan;290(1):E199-E203 10 Citations |
| 2 | Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries. (Zhu D, Medhora M, Campbell WB, Spitzbarth N, Baker JE, Jacobs ER) Circ Res 2003 May 16;92(9):992-1000 142 Citations |
| 1 | Oxygen-dependent expression of hypoxia-inducible factor-1alpha in renal medullary cells of rats. (Zou AP, Yang ZZ, Li PL, Cowley AW JR) Physiol Genomics 2001 Aug 28;6(3):159-68 52 Citations |
| 1 | HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation. (Yu F, White SB, Zhao Q, Lee FS) Proc Natl Acad Sci U S A 2001 Aug 14;98(17):9630-5 726 Citations |
| 1 | Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein. (Yu F, White SB, Zhao Q, Lee FS) Cancer Res 2001 May 15;61(10):4136-42 82 Citations |
| 2 | Increased mitochondrial K(ATP) channel activity during chronic myocardial hypoxia: is cardioprotection mediated by improved bioenergetics? (Eells JT, Henry MM, Gross GJ, Baker JE) Circ Res 2000 Nov 10;87(10):915-21 65 Citations |
| 1 | Augmented endothelium-dependent constriction to hypoxia early and late following reperfusion of the canine coronary artery. (Pearson PJ, Lin PJ, Schaff HV, Vanhoutte PM) Clin Exp Pharmacol Physiol 1996 Aug;23(8):634-41 31 Citations |
| 1 | Vasoconstriction to hypoxia of the human internal mammary artery. (Lin PJ, Pearson PJ, Schaff HV) Changgeng Yi Xue Za Zhi 1991 Sep;14(3):141-8 |