| 1 | CID-6033590 inhibits p38MAPK pathway and induces S-phase cell cycle arrest and apoptosis in DU145 and PC-3 cells. (Sharma GP, Gurung SK, Inam A, Nigam L, Bist A, Mohapatra D, Senapati S, Subbarao N, Azam A, Mondal N) Toxicol In Vitro 2019 Oct;60:420-436 14 Citations |
| 1 | A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice. (Cecchini MJ, Thwaites MJ, Talluri S, MacDonald JI, Passos DT, Chong JL, Cantalupo P, Stafford PM, Sáenz-Robles MT, Francis SM, Pipas JM, Leone G, Welch I, Dick FA) Mol Cell Biol 2014 Jun;34(11):2029-45 28 Citations |
| 1 | Characterization of O-GlcNAc cycling and proteomic identification of differentially O-GlcNAcylated proteins during G1/S transition. (Drougat L, Olivier-Van Stichelen S, Mortuaire M, Foulquier F, Lacoste AS, Michalski JC, Lefebvre T, Vercoutter-Edouart AS) Biochim Biophys Acta 2012 Dec;1820(12):1839-48 58 Citations |
| 1 | E2f1-3 are critical for myeloid development. (Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G) J Biol Chem 2011 Feb 11;286(6):4783-95 34 Citations |
| 2 | The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone. (Rao VA, Klein SR, Bonar SJ, Zielonka J, Mizuno N, Dickey JS, Keller PW, Joseph J, Kalyanaraman B, Shacter E) J Biol Chem 2010 Nov 05;285(45):34447-59 132 Citations |
| 1 | Celecoxib toxicity is cell cycle phase specific. (Bock JM, Menon SG, Sinclair LL, Bedford NS, Goswami PC, Domann FE, Trask DK) Cancer Res 2007 Apr 15;67(8):3801-8 38 Citations |
| 1 | Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation. (Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G) J Biol Chem 2006 Nov 24;281(47):36124-31 66 Citations |
| 1 | Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer. (Strock CJ, Park JI, Rosen DM, Ruggeri B, Denmeade SR, Ball DW, Nelkin BD) J Clin Endocrinol Metab 2006 Jan;91(1):79-84 44 Citations |
| 1 | Role of RhoA, mDia, and ROCK in cell shape-dependent control of the Skp2-p27kip1 pathway and the G1/S transition. (Mammoto A, Huang S, Moore K, Oh P, Ingber DE) J Biol Chem 2004 Jun 18;279(25):26323-30 197 Citations |
| 1 | Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. (Nanba D, Mammoto A, Hashimoto K, Higashiyama S) J Cell Biol 2003 Nov 10;163(3):489-502 141 Citations |
| 1 | Endostatin is a potential inhibitor of Wnt signaling. (Hanai J, Gloy J, Karumanchi SA, Kale S, Tang J, Hu G, Chan B, Ramchandran R, Jha V, Sukhatme VP, Sokol S) J Cell Biol 2002 Aug 05;158(3):529-39 145 Citations |
| 1 | The E2F1-3 transcription factors are essential for cellular proliferation. (Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G) Nature 2001 Nov 22;414(6862):457-62 537 Citations |
| 1 | Myc requires distinct E2F activities to induce S phase and apoptosis. (Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, Smith C, Nevins JR) Mol Cell 2001 Jul;8(1):105-13 226 Citations |
| 1 | Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase. (Leone G, DeGregori J, Jakoi L, Cook JG, Nevins JR) Proc Natl Acad Sci U S A 1999 Jun 08;96(12):6626-31 77 Citations |
| 1 | Ras enhances Myc protein stability. (Sears R, Leone G, DeGregori J, Nevins JR) Mol Cell 1999 Feb;3(2):169-79 406 Citations |
| 1 | Carcinoma of the breast in males: a multiinstitutional survey. (Donegan WL, Redlich PN, Lang PJ, Gall MT) Cancer 1998 Aug 01;83(3):498-509 208 Citations |
| 1 | E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. (Leone G, DeGregori J, Yan Z, Jakoi L, Ishida S, Williams RS, Nevins JR) Genes Dev 1998 Jul 15;12(14):2120-30 341 Citations |
| 1 | Role of the Rb/E2F pathway in cell growth control. (Nevins JR, Leone G, DeGregori J, Jakoi L) J Cell Physiol 1997 Nov;173(2):233-6 182 Citations |
| 1 | Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. (Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR) Nature 1997 May 22;387(6631):422-6 416 Citations |
| 1 | E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity. (DeGregori J, Leone G, Ohtani K, Miron A, Nevins JR) Genes Dev 1995 Dec 01;9(23):2873-87 204 Citations |
