| 1 | Radiogenomic Profiling of Prostate Tumors prior to External Beam Radiotherapy Converges on a Transcriptomic Signature of TGF-β Activity Driving Tumor Recurrence. (Ku AT, Shankavaram U, Trostel SY, Zhang H, Kartal S, Sater HA, Harmon SA, Carrabba NV, Liu Y, Ryu H, Proudfoot JA, Hong BH, Wood BJ, Pinto PA, Choyke PL, Roach M, Sandler HM, Pugh SL, Zeitzer KL, Mendez LC, Kapadia NS, Hall WA, Desai AB, Stoyanova RS, Pollack A, Davicioni E, Chua MLK, Turkbey B, Sowalsky AG, Citrin DE) Clin Cancer Res 2025 Dec 15;31(24):5211-5224 |
| 1 | Distinct gene expression profiles underlie morphological and etiological differences in pediatric cataracts. (Shanbagh S, Matalia J, Kannan R, Shetty R, Panmand P, Muthu SO, Chaurasia SS, Deshpande V, Bhattacharya SS, Gopalakrishnan AV, Ghosh A) Indian J Ophthalmol 2023 May;71(5):2143-2151 2 Citations |
| 1 | Innatus immunis: Evolving paradigm of adaptive NK cells. (Khalil M, Malarkannan S) J Exp Med 2022 Nov 07;219(11) 1 Citation |
| 2 | Mitigation of Multi-Organ Radiation Injury with ACE2 Agonist Diminazene Aceturate. (Gasperetti T, Sharma GP, Frei AC, Pierce L, Veley D, Szalewski N, Narayanan J, Fish BL, Himburg HA) Radiat Res 2022 Oct 01;198(4):325-335 8 Citations |
| 2 | Toll-like receptor-9 stimulated plasmacytoid dendritic cell precursors suppress autoimmune neuroinflammation in a murine model of multiple sclerosis. (Letscher H, Agbogan VA, Korniotis S, Gastineau P, Tejerina E, Gras C, Mégret J, Moe A, Drobyski WR, Zavala F) Sci Rep 2021 Feb 26;11(1):4735 13 Citations |
| 1 | Differential Expression of Cytokine-Coding Genes among Migraine Patients with and without Aura and Normal Subjects. (Taheri M, Nicknafs F, Hesami O, Javadi A, Arsang-Jang S, Sayad A, Ghafouri-Fard S) J Mol Neurosci 2021 Jun;71(6):1197-1204 15 Citations |
| 1 | Epigenomic Evaluation of Cholangiocyte Transforming Growth Factor-β Signaling Identifies a Selective Role for Histone 3 Lysine 9 Acetylation in Biliary Fibrosis. (Aseem SO, Jalan-Sakrikar N, Chi C, Navarro-Corcuera A, De Assuncao TM, Hamdan FH, Chowdhury S, Banales JM, Johnsen SA, Shah VH, Huebert RC) Gastroenterology 2021 Feb;160(3):889-905.e10 45 Citations |
| 1 | miR-146b-5p has a sex-specific role in renal and cardiac pathology in a rat model of chronic kidney disease. (Paterson MR, Geurts AM, Kriegel AJ) Kidney Int 2019 Dec;96(6):1332-1345 35 Citations |
| 1 | β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial-mesenchymal transition. (Cui Y, Jiang L, Yu R, Shao Y, Mei L, Tao Y) J Ethnopharmacol 2019 Oct 28;243:112096 41 Citations |
| 1 | Knockout of Dual-Specificity Protein Phosphatase 5 Protects Against Hypertension-Induced Renal Injury. (Zhang C, He X, Murphy SR, Zhang H, Wang S, Ge Y, Gao W, Williams JM, Geurts AM, Roman RJ, Fan F) J Pharmacol Exp Ther 2019 Aug;370(2):206-217 21 Citations |
| 2 | CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis. (Ligresti G, Caporarello N, Meridew JA, Jones DL, Tan Q, Choi KM, Haak AJ, Aravamudhan A, Roden AC, Prakash YS, Lomberk G, Urrutia RA, Tschumperlin DJ) JCI Insight 2019 May 16;5(12) 77 Citations |
| 4 | Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis. (Martin-Mateos R, De Assuncao TM, Arab JP, Jalan-Sakrikar N, Yaqoob U, Greuter T, Verma VK, Mathison AJ, Cao S, Lomberk G, Mathurin P, Urrutia R, Huebert RC, Shah VH) Cell Mol Gastroenterol Hepatol 2019;7(1):197-209 67 Citations |
| 1 | From Hepatocyte to Cholangiocyte: The Remarkable Potential of Transdifferentiation to Treat Cholestatic Diseases. (Kamath B, Mack C) Hepatology 2019 Apr;69(4):1828-1830 4 Citations |
| 2 | The Immune Landscape of Cancer. (Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS, Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I) Immunity 2018 Apr 17;48(4):812-830.e14 4120 Citations |
| 3 | Twist1 in Hypoxia-induced Pulmonary Hypertension through Transforming Growth Factor-β-Smad Signaling. (Mammoto T, Muyleart M, Konduri GG, Mammoto A) Am J Respir Cell Mol Biol 2018 Feb;58(2):194-207 82 Citations |
| 3 | Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys-Dietz syndrome (LDS) impairs canonical TGF-β signaling. (Cousin MA, Zimmermann MT, Mathison AJ, Blackburn PR, Boczek NJ, Oliver GR, Lomberk GA, Urrutia RA, Deyle DR, Klee EW) Cold Spring Harb Mol Case Stud 2017 Jul;3(4) 8 Citations |
| 1 | Effect of position-specific single-point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients. (Anandalakshmi V, Murugan E, Leng EGT, Ting LW, Chaurasia SS, Yamazaki T, Nagashima T, George BL, Peh GSL, Pervushin K, Lakshminarayanan R, Mehta JS) Biochem J 2017 May 09;474(10):1705-1725 17 Citations |
| 2 | Is lumbar facet fusion biomechanically equivalent to lumbar posterolateral onlay fusion? (Toth JM, Foley KT, Wang M, Seim HB 3rd, Simon Turner A) J Neurosurg Spine 2017 May;26(5):586-593 8 Citations |
| 1 | Transient Local Bone Remodeling Effects of rhBMP-2 in an Ovine Interbody Spine Fusion Model. (Bae HW, Patel VV, Sardar ZM, Badura JM, Pradhan BB, Seim HB 3rd, Turner AS, Toth JM) J Bone Joint Surg Am 2016 Dec 21;98(24):2061-2070 25 Citations |
| 2 | Radiographic, biomechanical, and histological evaluation of rhBMP-2 in a 3-level intertransverse process spine fusion: an ovine study. (Toth JM, Wang M, Lawson J, Badura JM, DuBose KB) J Neurosurg Spine 2016 Dec;25(6):733-739 8 Citations |
| 1 | pH Induced Conformational Transitions in the Transforming Growth Factor β-Induced Protein (TGFβIp) Associated Corneal Dystrophy Mutants. (Murugan E, Venkatraman A, Lei Z, Mouvet V, Rui Yi Lim R, Muruganantham N, Goh E, Swee Lim Peh G, Beuerman RW, Chaurasia SS, Rajamani L, Mehta JS) Sci Rep 2016 Mar 31;6:23836 9 Citations |
| 2 | The adhesion molecule PECAM-1 enhances the TGF-β-mediated inhibition of T cell function. (Newman DK, Fu G, Adams T, Cui W, Arumugam V, Bluemn T, Riese MJ) Sci Signal 2016 Mar 08;9(418):ra27 21 Citations |
| 1 | ITF2357 transactivates Id3 and regulate TGFβ/BMP7 signaling pathways to attenuate corneal fibrosis. (Lim RR, Tan A, Liu YC, Barathi VA, Mohan RR, Mehta JS, Chaurasia SS) Sci Rep 2016 Feb 11;6:20841 47 Citations |
| 3 | Intact Regulatory T-Cell Function but Defective Generation of IL-17A-Producing CD4+ T Cells in XIAP Deficiency. (Gurram B, Hammelev E, Syverson G, Haribhai D, Yan K, Simpson P, Salzman N, Verbsky JW) J Pediatr Gastroenterol Nutr 2016 Aug;63(2):218-25 |
| 1 | Systematic Review and Meta-Analysis of Recombinant Human Bone Morphogenetic Protein-2 in Localized Alveolar Ridge and Maxillary Sinus Augmentation. (Kelly MP, Vaughn OL, Anderson PA) J Oral Maxillofac Surg 2016 May;74(5):928-39 71 Citations |
| 2 | Plasma-induced signatures reveal an extracellular milieu possessing an immunoregulatory bias in treatment-naive paediatric inflammatory bowel disease. (Gurram B, Salzman NH, Kaldunski ML, Jia S, Li BU, Stephens M, Sood MR, Hessner MJ) Clin Exp Immunol 2016 Apr;184(1):36-49 16 Citations |
| 1 | Instrumented Lumbar Corpectomy and Spinal Reconstruction Comparing rhBMP-2/Compression-Resistant Matrix, rhBMP-2/Absorbable Collagen Sponge/Ceramic Granules Mixture, and Autograft in Two Different Devices: A Study in Sheep. (Toth JM, Schwartz DG, Mobasser JP, Williams J) Spine (Phila Pa 1976) 2016 Mar;41(6):E313-22 |
| 2 | Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats. (Wang H, Weihrauch D, Kersten JR, Toth JM, Passerini AG, Rajamani A, Schrepfer S, LaDisa JF Jr) Am J Physiol Heart Circ Physiol 2015 Oct;309(7):H1130-40 10 Citations |
| 2 | TCR signaling intensity controls CD8+ T cell responsiveness to TGF-β. (Arumugam V, Bluemn T, Wesley E, Schmidt AM, Kambayashi T, Malarkannan S, Riese MJ) J Leukoc Biol 2015 Nov;98(5):703-12 25 Citations |
| 1 | Biochemical properties and aggregation propensity of transforming growth factor-induced protein (TGFBIp) and the amyloid forming mutants. (Lakshminarayanan R, Chaurasia SS, Murugan E, Venkatraman A, Chai SM, Vithana EN, Beuerman RW, Mehta JS) Ocul Surf 2015 Jan;13(1):9-25 13 Citations |
| 1 | Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes. (Papadakis KA, Krempski J, Reiter J, Svingen P, Xiong Y, Sarmento OF, Huseby A, Johnson AJ, Lomberk GA, Urrutia RA, Faubion WA) Am J Physiol Cell Physiol 2015 Mar 01;308(5):C362-71 26 Citations |
| 2 | Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. (Bohnsack RN, Warejcka DJ, Wang L, Gillespie SR, Bernstein AM, Twining SS, Dahms NM) Invest Ophthalmol Vis Sci 2014 Oct 30;55(12):7697-708 20 Citations |
| 1 | Clinical and genetic aspects of the TGFBI-associated corneal dystrophies. (Lakshminarayanan R, Chaurasia SS, Anandalakshmi V, Chai SM, Murugan E, Vithana EN, Beuerman RW, Mehta JS) Ocul Surf 2014 Oct;12(4):234-51 67 Citations |
| 1 | Reducing CD73 expression by IL1β-Programmed Th17 cells improves immunotherapeutic control of tumors. (Chatterjee S, Thyagarajan K, Kesarwani P, Song JH, Soloshchenko M, Fu J, Bailey SR, Vasu C, Kraft AS, Paulos CM, Yu XZ, Mehrotra S) Cancer Res 2014 Nov 01;74(21):6048-59 50 Citations |
| 1 | Cytokines associated with necrotizing enterocolitis in extremely-low-birth-weight infants. (Maheshwari A, Schelonka RL, Dimmitt RA, Carlo WA, Munoz-Hernandez B, Das A, McDonald SA, Thorsen P, Skogstrand K, Hougaard DM, Higgins RD, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network) Pediatr Res 2014 Jul;76(1):100-8 130 Citations |
| 1 | Prostaglandin E2 modifies SMAD2 and promotes SMAD2-SMAD4 complex formation. (Yang C, Chen C, Sorokin A) Prostaglandins Leukot Essent Fatty Acids 2014 May;90(5):145-9 2 Citations |
| 1 | TGF-β: duality of function between tumor prevention and carcinogenesis. (Principe DR, Doll JA, Bauer J, Jung B, Munshi HG, Bartholin L, Pasche B, Lee C, Grippo PJ) J Natl Cancer Inst 2014 Feb;106(2):djt369 466 Citations |
| 1 | Tgfβ-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves. (Barnette DN, Hulin A, Ahmed AS, Colige AC, Azhar M, Lincoln J) J Mol Cell Cardiol 2013 Dec;65:137-46 36 Citations |
| 2 | Temporal induction of immunoregulatory processes coincides with age-dependent resistance to viral-induced type 1 diabetes. (Chen YG, Mordes JP, Blankenhorn EP, Kashmiri H, Kaldunski ML, Jia S, Geoffrey R, Wang X, Hessner MJ) Genes Immun 2013 Sep;14(6):387-400 12 Citations |
| 2 | A novel role of the Sp/KLF transcription factor KLF11 in arresting progression of endometriosis. (Daftary GS, Zheng Y, Tabbaa ZM, Schoolmeester JK, Gada RP, Grzenda AL, Mathison AJ, Keeney GL, Lomberk GA, Urrutia R) PLoS One 2013;8(3):e60165 43 Citations |
| 1 | Early-term and mid-term histologic events during single-level posterolateral intertransverse process fusion with rhBMP-2/collagen carrier and a ceramic bulking agent in a nonhuman primate model: implications for bone graft preparation. (Khan SN, Toth JM, Gupta K, Glassman SD, Gupta MC) J Spinal Disord Tech 2014 Jun;27(4):212-9 8 Citations |
| 2 | Hyperglycemia reduces proteoglycan levels in tendons. (Burner T, Gohr C, Mitton-Fitzgerald E, Rosenthal AK) Connect Tissue Res 2012;53(6):535-41 53 Citations |
| 1 | Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression. (Kohn EA, Yang YA, Du Z, Nagano Y, Van Schyndle CM, Herrmann MA, Heldman M, Chen JQ, Stuelten CH, Flanders KC, Wakefield LM) Mol Cancer Res 2012 Oct;10(10):1389-99 20 Citations |
| 1 | Targeting regulatory T cells in the treatment of type 1 diabetes mellitus. (Cabrera SM, Rigby MR, Mirmira RG) Curr Mol Med 2012 Dec;12(10):1261-72 49 Citations |
| 1 | Expression, purification and characterization of fourth FAS1 domain of TGFβIp-associated corneal dystrophic mutants. (Elavazhagan M, Lakshminarayanan R, Zhou L, Ting LW, Tong L, Beuerman RW, Chaurasia SS, Mehta JS) Protein Expr Purif 2012 Jul;84(1):108-15 14 Citations |
| 3 | Requirements for growth and IL-10 expression of highly purified human T regulatory cells. (Bonacci B, Edwards B, Jia S, Williams CB, Hessner MJ, Gauld SB, Verbsky JW) J Clin Immunol 2012 Oct;32(5):1118-28 11 Citations |
| 1 | Degradation of internalized αvβ5 integrin is controlled by uPAR bound uPA: effect on β1 integrin activity and α-SMA stress fiber assembly. (Wang L, Pedroja BS, Meyers EE, Garcia AL, Twining SS, Bernstein AM) PLoS One 2012;7(3):e33915 23 Citations |
| 1 | Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension. (Maloney JP, Stearman RS, Bull TM, Calabrese DW, Tripp-Addison ML, Wick MJ, Broeckel U, Robbins IM, Wheeler LA, Cogan JD, Loyd JE) Am J Physiol Lung Cell Mol Physiol 2012 Mar 15;302(6):L541-54 41 Citations |
| 1 | Evolution of treatment for diabetic nephropathy: historical progression from RAAS inhibition and onward. (Blumenthal SS) Postgrad Med 2011 Nov;123(6):166-79 10 Citations |
| 1 | Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly. (Veerapathran A, Pidala J, Beato F, Yu XZ, Anasetti C) Blood 2011 Nov 17;118(20):5671-80 127 Citations |
| 1 | A novel mutation in transforming growth factor-beta induced protein (TGFβIp) reveals secondary structure perturbation in lattice corneal dystrophy. (Lakshminarayanan R, Vithana EN, Chai SM, Chaurasia SS, Saraswathi P, Venkatraman A, Rojare C, Venkataraman D, Tan D, Aung T, Beuerman RW, Mehta JS) Br J Ophthalmol 2011 Oct;95(10):1457-62 27 Citations |
| 1 | ChIP-seq defined genome-wide map of TGFβ/SMAD4 targets: implications with clinical outcome of ovarian cancer. (Kennedy BA, Deatherage DE, Gu F, Tang B, Chan MW, Nephew KP, Huang TH, Jin VX) PLoS One 2011;6(7):e22606 30 Citations |
| 1 | Efficient and selective prevention of GVHD by antigen-specific induced Tregs via linked-suppression in mice. (Semple K, Yu Y, Wang D, Anasetti C, Yu XZ) Biol Blood Marrow Transplant 2011 Mar;17(3):309-18 43 Citations |
| 1 | A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland. (Kohn EA, Du Z, Sato M, Van Schyndle CM, Welsh MA, Yang YA, Stuelten CH, Tang B, Ju W, Bottinger EP, Wakefield LM) Breast Cancer Res 2010;12(5):R83 22 Citations |
| 1 | Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-beta activation. (Fitchev PP, Wcislak SM, Lee C, Bergh A, Brendler CB, Stellmach VM, Crawford SE, Mavroudis CD, Cornwell ML, Doll JA) Lab Invest 2010 Jul;90(7):1078-90 23 Citations |
| 1 | Conservation of the TGFbeta/Labial homeobox signaling loop in endoderm-derived cells between Drosophila and mammals. (Lomberk GA, Imoto I, Gebelein B, Urrutia R, Cook TA) Pancreatology 2010;10(1):74-84 3 Citations |
| 1 | Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expression. (Relland LM, Mishra MK, Haribhai D, Edwards B, Ziegelbauer J, Williams CB) J Immunol 2009 Feb 01;182(3):1341-50 26 Citations |
| 1 | Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling. (Truty MJ, Lomberk G, Fernandez-Zapico ME, Urrutia R) J Biol Chem 2009 Mar 06;284(10):6291-300 57 Citations |
| 1 | Aging alters gene expression of growth and remodeling factors in human skeletal muscle both at rest and in response to acute resistance exercise. (Dennis RA, Przybyla B, Gurley C, Kortebein PM, Simpson P, Sullivan DH, Peterson CA) Physiol Genomics 2008 Feb 19;32(3):393-400 89 Citations |
| 1 | Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF. (Fujita K, Janz S) Mol Cancer 2007 Oct 30;6:71 160 Citations |
| 1 | ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts. (Grobe JL, Der Sarkissian S, Stewart JM, Meszaros JG, Raizada MK, Katovich MJ) Clin Sci (Lond) 2007 Oct;113(8):357-64 77 Citations |
| 1 | Serum cytokines as biomarkers of disease and clues to pathogenesis. (Mack CL) Hepatology 2007 Jul;46(1):6-8 24 Citations |
| 1 | Effect on bone induction of using contrast media to reconstitute recombinant human bone morphogenetic protein-2 in an ectopic model in rats. (Zanella JM, Oliver C, Peckham SM, McKay B, Toth JM, Boden SD) J Neurosurg Spine 2006 Nov;5(5):434-9 1 Citation |
| 1 | Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7). (Grobe JL, Mecca AP, Lingis M, Shenoy V, Bolton TA, Machado JM, Speth RC, Raizada MK, Katovich MJ) Am J Physiol Heart Circ Physiol 2007 Feb;292(2):H736-42 320 Citations |
| 1 | Lessons learned from psoriatic plaques concerning mechanisms of tissue repair, remodeling, and inflammation. (Nickoloff BJ, Bonish BK, Marble DJ, Schriedel KA, DiPietro LA, Gordon KB, Lingen MW) J Investig Dermatol Symp Proc 2006 Sep;11(1):16-29 67 Citations |
| 1 | The interaction of adenovirus E1A with p300 family members modulates cellular gene expression to reduce tumorigenicity. (Miura TA, Cook JL, Potter TA, Ryan S, Routes JM) J Cell Biochem 2007 Mar 01;100(4):929-40 5 Citations |
| 1 | Soluble endoglin contributes to the pathogenesis of preeclampsia. (Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA) Nat Med 2006 Jun;12(6):642-9 1626 Citations |
| 1 | BMP and FGF regulatory pathways control cell lineage diversification of heart valve precursor cells. (Lincoln J, Alfieri CM, Yutzey KE) Dev Biol 2006 Apr 15;292(2):292-302 100 Citations |
| 1 | Hearts and bones: shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development. (Lincoln J, Lange AW, Yutzey KE) Dev Biol 2006 Jun 15;294(2):292-302 167 Citations |
| 1 | A member of the transforming growth factor-beta receptor family from Echinococcus multilocularis is activated by human bone morphogenetic protein 2. (Zavala-Góngora R, Kroner A, Bernthaler P, Knaus P, Brehm K) Mol Biochem Parasitol 2006 Apr;146(2):265-71 43 Citations |
| 1 | Expression of lysyl oxidase and transforming growth factor beta2 in women with severe pelvic organ prolapse. (Kobak W, Lu J, Hardart A, Zhang C, Stanczyk FZ, Felix JC) J Reprod Med 2005 Nov;50(11):827-31 27 Citations |
| 2 | Polyetheretherketone as a biomaterial for spinal applications. (Toth JM, Wang M, Estes BT, Scifert JL, Seim HB 3rd, Turner AS) Biomaterials 2006 Jan;27(3):324-34 496 Citations |
| 1 | Epicutaneously induced TGF-beta-dependent tolerance inhibits experimental autoimmune encephalomyelitis. (Szczepanik M, Tutaj M, Bryniarski K, Dittel BN) J Neuroimmunol 2005 Jul;164(1-2):105-14 47 Citations |
| 1 | Epicutaneous immunization induces alphabeta T-cell receptor CD4 CD8 double-positive non-specific suppressor T cells that inhibit contact sensitivity via transforming growth factor-beta. (Szczepanik M, Bryniarski K, Tutaj M, Ptak M, Skrzeczynska J, Askenase PW, Ptak W) Immunology 2005 May;115(1):42-54 57 Citations |
| 1 | Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy. (Torrealba JR, Colburn M, Golner S, Chang Z, Scheunemann T, Fechner JH, Roenneburg D, Hu H, Alam T, Kim HT, Kanmaz T, Oberley T, Knechtle SJ, Hamawy MM) Am J Transplant 2005 Jan;5(1):58-67 17 Citations |
| 1 | Ontogeny of vascular growth factors in perinatal sheep myocardium. (van Natta TL, Ralphe JC, Mascio CE, Bedell KA, Scholz TD, Segar JL) J Soc Gynecol Investig 2004 Dec;11(8):503-10 3 Citations |
| 1 | Dose dependence and time course of the immunologic response to administration of standardized cat allergen extract. (Nanda A, O'connor M, Anand M, Dreskin SC, Zhang L, Hines B, Lane D, Wheat W, Routes JM, Sawyer R, Rosenwasser LJ, Nelson HS) J Allergy Clin Immunol 2004 Dec;114(6):1339-44 138 Citations |
| 1 | Cartilage-derived morphogenetic protein-1 promotes the differentiation of mesenchymal stem cells into chondrocytes. (Bai X, Xiao Z, Pan Y, Hu J, Pohl J, Wen J, Li L) Biochem Biophys Res Commun 2004 Dec 10;325(2):453-60 85 Citations |
| 1 | Role of pressure in angiotensin II-induced renal injury: chronic servo-control of renal perfusion pressure in rats. (Mori T, Cowley AW Jr) Hypertension 2004 Apr;43(4):752-9 111 Citations |
| 1 | Astrocyte regulation of human brain capillary endothelial fibrinolysis. (Kim JA, Tran ND, Wang SJ, Fisher MJ) Thromb Res 2003;112(3):159-65 30 Citations |
| 1 | Transforming growth factor-beta1 inhibition of vascular smooth muscle cell activation is mediated via Smad3. (Feinberg MW, Watanabe M, Lebedeva MA, Depina AS, Hanai J, Mammoto T, Frederick JP, Wang XF, Sukhatme VP, Jain MK) J Biol Chem 2004 Apr 16;279(16):16388-93 66 Citations |
| 1 | Identification and characterisation of two distinct Smad proteins from the fox-tapeworm Echinococcus multilocularis. (Zavala-Góngora R, Kroner A, Wittek B, Knaus P, Brehm K) Int J Parasitol 2003 Dec;33(14):1665-77 39 Citations |
| 1 | Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. (Budisavljevic MN, Hodge L, Barber K, Fulmer JR, Durazo-Arvizu RA, Self SE, Kuhlmann M, Raymond JR, Greene EL) Am J Physiol Renal Physiol 2003 Dec;285(6):F1138-48 55 Citations |
| 1 | Transforming growth factor beta1 receptor II is downregulated by E1A in adenovirus-infected cells. (Tarakanova VL, Wold WS) J Virol 2003 Sep;77(17):9324-36 9 Citations |
| 1 | BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. (Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R) Nat Med 2003 Jul;9(7):964-8 1256 Citations |
| 2 | Evaluation of 70/30 poly (L-lactide-co-D,L-lactide) for use as a resorbable interbody fusion cage. (Toth JM, Estes BT, Wang M, Seim HB 3rd, Scifert JL, Turner AS, Cornwall GB) J Neurosurg 2002 Nov;97(4 Suppl):423-32 48 Citations |
| 1 | Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells. (Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ) Clin Cancer Res 2002 Nov;8(11):3628-38 59 Citations |
| 1 | Epicutaneous application of protein antigens incorporated into cosmetic cream induces antigen-nonspecific unresponsiveness in mice and affects the cell-mediated immune response. (Ptak W, Szczepanik M, Bryniarski K, Tutaj M, Ptak M) Int Arch Allergy Immunol 2002 May;128(1):8-14 31 Citations |
| 1 | Transglutaminase participates in the incorporation of latent TGFbeta into the extracellular matrix of aging articular chondrocytes. (Le M, Gohr CM, Rosenthal AK) Connect Tissue Res 2001;42(4):245-53 17 Citations |
| 1 | Effects of gestational age on myocardial blood flow and coronary flow reserve in pressure-loaded ovine fetal hearts. (Dalshaug GB, Scholz TD, Smith OM, Bedell KA, Caldarone CA, Segar JL) Am J Physiol Heart Circ Physiol 2002 Apr;282(4):H1359-69 17 Citations |
| 1 | Histologic evaluation of the efficacy of rhBMP-2 compared with autograft bone in sheep spinal anterior interbody fusion. (Sandhu HS, Toth JM, Diwan AD, Seim HB 3rd, Kanim LE, Kabo JM, Turner AS) Spine (Phila Pa 1976) 2002 Mar 15;27(6):567-75 106 Citations |
| 1 | Identification of endothelial cell genes expressed in an in vitro model of angiogenesis: induction of ESM-1, (beta)ig-h3, and NrCAM. (Aitkenhead M, Wang SJ, Nakatsu MN, Mestas J, Heard C, Hughes CC) Microvasc Res 2002 Mar;63(2):159-71 136 Citations |
| 1 | Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas. (Yen TW, Aardal NP, Bronner MP, Thorning DR, Savard CE, Lee SP, Bell RH Jr) Surgery 2002 Feb;131(2):129-34 119 Citations |
| 1 | Transforming growth factor beta-1 stimulates articular chondrocyte elaboration of matrix vesicles capable of greater calcium pyrophosphate precipitation. (Derfus BA, Camacho NP, Olmez U, Kushnaryov VM, Westfall PR, Ryan LM, Rosenthal AK) Osteoarthritis Cartilage 2001 Apr;9(3):189-94 22 Citations |
| 1 | Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. (Yamada M, Revelli JP, Eichele G, Barron M, Schwartz RJ) Dev Biol 2000 Dec 01;228(1):95-105 186 Citations |
| 1 | CD36 and atherosclerosis. (Silverstein RL, Febbraio M) Curr Opin Lipidol 2000 Oct;11(5):483-91 113 Citations |
| 1 | Practical illustrations in tissue engineering: surgical considerations relevant to the implantation of osteoinductive devices. (Vögelin E, Jones NF, Huang JI, Brekke JH, Toth JM) Tissue Eng 2000 Aug;6(4):449-60 13 Citations |
| 1 | Participation of transglutaminase in the activation of latent transforming growth factor beta1 in aging articular cartilage. (Rosenthal AK, Gohr CM, Henry LA, Le M) Arthritis Rheum 2000 Aug;43(8):1729-33 44 Citations |
| 1 | Requirement for BMP and FGF signaling during cardiogenic induction in non-precardiac mesoderm is specific, transient, and cooperative. (Barron M, Gao M, Lough J) Dev Dyn 2000 Jun;218(2):383-93 146 Citations |
| 1 | TGF-beta 2 reduces demyelination, virus antigen expression, and macrophage recruitment in a viral model of multiple sclerosis. (Drescher KM, Murray PD, Lin X, Carlino JA, Rodriguez M) J Immunol 2000 Mar 15;164(6):3207-13 37 Citations |
| 1 | Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle. (Chiao PJ, Hunt KK, Grau AM, Abramian A, Fleming J, Zhang W, Breslin T, Abbruzzese JL, Evans DB) Ann N Y Acad Sci 1999 Jun 30;880:31-7 31 Citations |
| 1 | Serotonin 5-HT2A receptor induces TGF-beta1 expression in mesangial cells via ERK: proliferative and fibrotic signals. (Grewal JS, Mukhin YV, Garnovskaya MN, Raymond JR, Greene EL) Am J Physiol 1999 Jun;276(6):F922-30 136 Citations |
| 1 | The use of recombinant human bone morphogenetic protein 2 (rhBMP-2) to promote spinal fusion in a nonhuman primate anterior interbody fusion model. (Hecht BP, Fischgrund JS, Herkowitz HN, Penman L, Toth JM, Shirkhoda A) Spine (Phila Pa 1976) 1999 Apr 01;24(7):629-36 149 Citations |
| 1 | MDS1/EVI1 enhances TGF-beta1 signaling and strengthens its growth-inhibitory effect but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-beta1. (Sood R, Talwar-Trikha A, Chakrabarti SR, Nucifora G) Leukemia 1999 Mar;13(3):348-57 108 Citations |
| 1 | Thyroid hormones induce features of the hypertrophic phenotype and stimulate correlates of CPPD crystal formation in articular chondrocytes. (Rosenthal AK, Henry LA) J Rheumatol 1999 Feb;26(2):395-401 41 Citations |
| 1 | Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells. (Hunt KK, Fleming JB, Abramian A, Zhang L, Evans DB, Chiao PJ) Cancer Res 1998 Dec 15;58(24):5656-61 50 Citations |
| 1 | Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry. (Yoshioka H, Meno C, Koshiba K, Sugihara M, Itoh H, Ishimaru Y, Inoue T, Ohuchi H, Semina EV, Murray JC, Hamada H, Noji S) Cell 1998 Aug 07;94(3):299-305 332 Citations |
| 1 | Association of MSX1 and TGFB3 with nonsyndromic clefting in humans. (Lidral AC, Romitti PA, Basart AM, Doetschman T, Leysens NJ, Daack-Hirsch S, Semina EV, Johnson LR, Machida J, Burds A, Parnell TJ, Rubenstein JL, Murray JC) Am J Hum Genet 1998 Aug;63(2):557-68 265 Citations |
| 1 | Z-138: a new mature B-cell acute lymphoblastic leukemia cell line from a patient with transformed chronic lymphocytic leukemia. (Estrov Z, Talpaz M, Ku S, Harris D, Van Q, Beran M, Hirsch-Ginsberg C, Huh Y, Yee G, Kurzrock R) Leuk Res 1998 Apr;22(4):341-53 33 Citations |
| 1 | Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. (Grau AM, Zhang L, Wang W, Ruan S, Evans DB, Abbruzzese JL, Zhang W, Chiao PJ) Cancer Res 1997 Sep 15;57(18):3929-34 148 Citations |
| 1 | Opposing effects of activin A and follistatin on developing skeletal muscle cells. (Link BA, Nishi R) Exp Cell Res 1997 Jun 15;233(2):350-62 52 Citations |
| 1 | Experimental spinal fusion with recombinant human bone morphogenetic protein-2 without decortication of osseous elements. (Sandhu HS, Kanim LE, Toth JM, Kabo JM, Liu D, Delamarter RB, Dawson EG) Spine (Phila Pa 1976) 1997 Jun 01;22(11):1171-80 110 Citations |
| 1 | Increased interleukin-6 production by cerebral cortical tissue of adult versus young mice. (Prechel MM, Halbur L, Devata S, Vaidya AM, Young MR) Mech Ageing Dev 1996 Dec 20;92(2-3):185-94 26 Citations |
| 1 | Effective doses of recombinant human bone morphogenetic protein-2 in experimental spinal fusion. (Sandhu HS, Kanim LE, Kabo JM, Toth JM, Zeegen EN, Liu D, Delamarter RB, Dawson EG) Spine (Phila Pa 1976) 1996 Sep 15;21(18):2115-22 176 Citations |
| 1 | Molecular and biologic characterization of a newly established Philadelphia-positive acute lymphoblastic leukemia cell line (Z-33) with an autocrine response to GM-CSF. (Estrov Z, Talpaz M, Ku S, Harris D, LaPushin R, Koller CA, Hirsh-Ginsberg C, Huh Y, Yee G, Kurzrock R) Leukemia 1996 Sep;10(9):1534-43 17 Citations |
| 1 | Combined BMP-2 and FGF-4, but neither factor alone, induces cardiogenesis in non-precardiac embryonic mesoderm. (Lough J, Barron M, Brogley M, Sugi Y, Bolender DL, Zhu X) Dev Biol 1996 Aug 25;178(1):198-202 195 Citations |
| 1 | Retinoic acid stimulates pyrophosphate elaboration by cartilage and chondrocytes. (Rosenthal AK, Henry LA) Calcif Tissue Int 1996 Aug;59(2):128-33 15 Citations |
| 1 | Transforming growth factor beta 1, a major stimulator of hyaluronan synthesis in human synovial lining cells. (Haubeck HD, Kock R, Fischer DC, Van de Leur E, Hoffmeister K, Greiling H) Arthritis Rheum 1995 May;38(5):669-77 58 Citations |
| 1 | Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression. (Udvadia AJ, Templeton DJ, Horowitz JM) Proc Natl Acad Sci U S A 1995 Apr 25;92(9):3953-7 200 Citations |
| 1 | Cloning of a canine cDNA homologous to the human transforming growth factor-beta 1-encoding gene. (Manning AM, Auchampach JA, Drong RF, Slightom JL) Gene 1995 Apr 03;155(2):307-8 14 Citations |
| 1 | Insulin-like growth factor-1 suppresses pyrophosphate elaboration by transforming growth factor beta1-stimulated chondrocytes and cartilage. (Olmez U, Ryan LM, Kurup IV, Rosenthal AK) Osteoarthritis Cartilage 1994 Sep;2(3):149-54 35 Citations |
| 1 | Ageing increases growth factor-induced inorganic pyrophosphate elaboration by articular cartilage. (Rosenthal AK, Ryan LM) Mech Ageing Dev 1994 Jul;75(1):35-44 21 Citations |
| 1 | Probenecid inhibits transforming growth factor-beta 1 induced pyrophosphate elaboration by chondrocytes. (Rosenthal AK, Ryan LM) J Rheumatol 1994 May;21(5):896-900 45 Citations |
| 1 | Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpression. (Udvadia AJ, Rogers KT, Higgins PD, Murata Y, Martin KH, Humphrey PA, Horowitz JM) Proc Natl Acad Sci U S A 1993 Apr 15;90(8):3265-9 198 Citations |
| 1 | A comparison of the effect of transforming growth factor beta 1 on pyrophosphate elaboration from various articular tissues. (Rosenthal AK, McCarty BA, Cheung HS, Ryan LM) Arthritis Rheum 1993 Apr;36(4):539-42 36 Citations |
| 1 | Transforming growth factor beta 1 stimulates inorganic pyrophosphate elaboration by porcine cartilage. (Rosenthal AK, Cheung HS, Ryan LM) Arthritis Rheum 1991 Jul;34(7):904-11 69 Citations |
| 1 | Constitutive expression of leukemia inhibitory factor RNA by human bone marrow stromal cells and modulation by IL-1, TNF-alpha, and TGF-beta. (Wetzler M, Talpaz M, Lowe DG, Baiocchi G, Gutterman JU, Kurzrock R) Exp Hematol 1991 Jun;19(5):347-51 87 Citations |
| 1 | Polypeptide growth factors in metanephric growth and segmental nephron differentiation. (Avner ED, Sweeney WE Jr) Pediatr Nephrol 1990 Jul;4(4):372-7 79 Citations |
© 2026 Clinical & Translational Science Institute