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Publications indexed to the term Proto-Oncogene Proteins c-myc

FacultyTitle
2Critical Role for Cap-Independent c-MYC Translation in Progression of Multiple Myeloma. (Shi Y, Sun F, Cheng Y, Holmes B, Dhakal B, Gera JF, Janz S, Lichtenstein A) Mol Cancer Ther 2022 Apr 01;21(4):502-510       3 Citations
7RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2021 Nov 02;37(5):109934       30 Citations
3Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia. (Gao X, Qin S, Wu Y, Chu C, Jiang B, Johnson RH, Kuang D, Zhang J, Wang X, Mehta A, Tew KD, Leone GW, Yu XZ, Wang H) J Clin Invest 2021 Aug 16;131(16)       21 Citations
1Generation of Human iPSCs by Protein Reprogramming and Stimulation of TLR3 Signaling. (Liu C, Ameen M, Himmati S, Thomas D, Sayed N) Methods Mol Biol 2021;2239:153-162       2 Citations
1Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation. (Meyer AE, Furumo Q, Stelloh C, Minella AC, Rao S) Neoplasia 2020 Nov;22(11):644-658       11 Citations
1Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice. (Wen Z, Rajagopalan A, Flietner ED, Yun G, Chesi M, Furumo Q, Burns RT, Papadas A, Ranheim EA, Pagenkopf AC, Morrow ZT, Finn R, Zhou Y, Li S, You X, Jensen J, Yu M, Cicala A, Menting J, Mitsiades CS, Callander NS, Bergsagel PL, Wang D, Asimakopoulos F, Zhang J) Blood 2021 Jan 07;137(1):61-74       16 Citations
1Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes. (Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin CM, Alontaga AY, McDaniel JM, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence HR, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha AM, Cleveland JL, Epling-Burnette PK) Blood 2020 Aug 13;136(7):857-870       15 Citations
1MYC needs MNT to drive B cells over the edge. (Janz S) Blood 2020 Mar 26;135(13):977-978       1 Citation
1CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia. (Pulikkan JA, Hegde M, Ahmad HM, Belaghzal H, Illendula A, Yu J, O'Hagan K, Ou J, Muller-Tidow C, Wolfe SA, Zhu LJ, Dekker J, Bushweller JH, Castilla LH) Cell 2018 Jun 28;174(1):172-186.e21       52 Citations
1Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. (Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H) Sci Adv 2018 Jan;4(1):eaar5701       30 Citations
1RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia. (Choi A, Illendula A, Pulikkan JA, Roderick JE, Tesell J, Yu J, Hermance N, Zhu LJ, Castilla LH, Bushweller JH, Kelliher MA) Blood 2017 Oct 12;130(15):1722-1733       53 Citations
1Outcomes of Patients With Double-Hit Lymphoma Who Achieve First Complete Remission. (Landsburg DJ, Falkiewicz MK, Maly J, Blum KA, Howlett C, Feldman T, Mato AR, Hill BT, Li S, Medeiros LJ, Torka P, Hernandez-Ilizaliturri F, Reddy NM, Singavi A, Fenske TS, Chavez JC, Kaplan JB, Behdad A, Petrich AM, Bast MA, Vose JM, Olszewski AJ, Costa C, Lansigan F, Gerson JN, Barta SK, Calzada O, Cohen JB, Lue JK, Amengual JE, Rivera X, Persky DO, Peace DJ, Nathan S, Cassaday RD) J Clin Oncol 2017 Jul 10;35(20):2260-2267       124 Citations
1FX11 inhibits aerobic glycolysis and growth of neuroblastoma cells. (Rellinger EJ, Craig BT, Alvarez AL, Dusek HL, Kim KW, Qiao J, Chung DH) Surgery 2017 Mar;161(3):747-752       28 Citations
1PIAS1 Promotes Lymphomagenesis through MYC Upregulation. (Rabellino A, Melegari M, Tompkins VS, Chen W, Van Ness BG, Teruya-Feldstein J, Conacci-Sorrell M, Janz S, Scaglioni PP) Cell Rep 2016 Jun 07;15(10):2266-2278       36 Citations
3The lncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis. (Iden M, Fye S, Li K, Chowdhury T, Ramchandran R, Rader JS) PLoS One 2016;11(5):e0156274       137 Citations
1KSHV-encoded vIL-6 collaborates with deregulated c-Myc to drive plasmablastic neoplasms in mice. (Rosean TR, Holman CJ, Tompkins VS, Jing X, Krasowski MD, Rose-John S, Janz S) Blood Cancer J 2016 Feb 26;6(2):e398       16 Citations
1Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice. (Tang X, Liu H, Srivastava A, Pécot T, Chen Z, Wang Q, Huang K, Sáenz-Robles MT, Cantalupo P, Pipas J, Leone G) Sci Data 2016 Feb 16;3:160008       5 Citations
2Wnt/β-Catenin Signaling Activation beyond Robust Nuclear β-Catenin Accumulation in Nondysplastic Barrett's Esophagus: Regulation via Dickkopf-1. (Lyros O, Rafiee P, Nie L, Medda R, Jovanovic N, Otterson MF, Behmaram B, Gockel I, Mackinnon A, Shaker R) Neoplasia 2015 Jul;17(7):598-611       16 Citations
1Targeting c-MYC in Platinum-Resistant Ovarian Cancer. (Reyes-González JM, Armaiz-Peña GN, Mangala LS, Valiyeva F, Ivan C, Pradeep S, Echevarría-Vargas IM, Rivera-Reyes A, Sood AK, Vivas-Mejía PE) Mol Cancer Ther 2015 Oct;14(10):2260-9       95 Citations
1Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. (Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, Sáenz-Robles MT, Cantalupo P, Pipas JM, Leone G) Nat Cell Biol 2015 Aug;17(8):1036-48       56 Citations
1A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma. (Wang F, Remke M, Bhat K, Wong ET, Zhou S, Ramaswamy V, Dubuc A, Fonkem E, Salem S, Zhang H, Hsieh TC, O'Rourke ST, Wu L, Li DW, Hawkins C, Kohane IS, Wu JM, Wu M, Taylor MD, Wu E) Oncotarget 2015 Feb 20;6(5):2709-24       17 Citations
1Silencing of CDC42 inhibits neuroblastoma cell proliferation and transformation. (Lee S, Craig BT, Romain CV, Qiao J, Chung DH) Cancer Lett 2014 Dec 28;355(2):210-6       21 Citations
1CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. (Huang CH, Lujambio A, Zuber J, Tschaharganeh DF, Doran MG, Evans MJ, Kitzing T, Zhu N, de Stanchina E, Sawyers CL, Armstrong SA, Lewis JS, Sherr CJ, Lowe SW) Genes Dev 2014 Aug 15;28(16):1800-14       154 Citations
1Viral oncogene expression in the stem/progenitor cell compartment of the mouse intestine induces adenomatous polyps. (Sáenz Robles MT, Chong JL, Koivisto C, Trimboli A, Liu H, Leone G, Pipas JM) Mol Cancer Res 2014 Oct;12(10):1355-64       3 Citations
1A new model of LMP1-MYC interaction in B cell lymphoma. (Ontiveros EP, Halwani A, Stunz LL, Kamberos N, Olivier AK, Janz S, Bishop GA) Leuk Lymphoma 2014 Dec;55(12):2917-23       5 Citations
1Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery. (Guan X, Mack DL, Moreno CM, Strande JL, Mathieu J, Shi Y, Markert CD, Wang Z, Liu G, Lawlor MW, Moorefield EC, Jones TN, Fugate JA, Furth ME, Murry CE, Ruohola-Baker H, Zhang Y, Santana LF, Childers MK) Stem Cell Res 2014 Mar;12(2):467-80       102 Citations
1Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis. (Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G) Oncogene 2015 Jan 02;34(1):119-28       27 Citations
1α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth. (Sengupta S, Weeraratne SD, Sun H, Phallen J, Rallapalli SK, Teider N, Kosaras B, Amani V, Pierre-Francois J, Tang Y, Nguyen B, Yu F, Schubert S, Balansay B, Mathios D, Lechpammer M, Archer TC, Tran P, Reimer RJ, Cook JM, Lim M, Jensen FE, Pomeroy SL, Cho YJ) Acta Neuropathol 2014 Apr;127(4):593-603       35 Citations
1Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. (Zhou X, Fan LX, Sweeney WE Jr, Denu JM, Avner ED, Li X) J Clin Invest 2013 Jul;123(7):3084-98       117 Citations
1Dual ALK and MYC rearrangements leading to an aggressive variant of anaplastic large cell lymphoma. (Liang X, Branchford B, Greffe B, McGavran L, Carstens B, Meltesen L, Albano EA, Quinones R, Cook B, Graham DK) J Pediatr Hematol Oncol 2013 Jul;35(5):e209-13       20 Citations
1Piperlongumine inhibits proliferation and survival of Burkitt lymphoma in vitro. (Han SS, Son DJ, Yun H, Kamberos NL, Janz S) Leuk Res 2013 Feb;37(2):146-54       46 Citations
1The feed-forward loop between YB-1 and MYC is essential for multiple myeloma cell survival. (Bommert KS, Effenberger M, Leich E, Küspert M, Murphy D, Langer C, Moll R, Janz S, Mottok A, Weissbach S, Rosenwald A, Bargou R, Bommert K) Leukemia 2013 Feb;27(2):441-50       44 Citations
1Characterization of ARF-BP1/HUWE1 interactions with CTCF, MYC, ARF and p53 in MYC-driven B cell neoplasms. (Qi CF, Kim YS, Xiang S, Abdullaev Z, Torrey TA, Janz S, Kovalchuk AL, Sun J, Chen D, Cho WC, Gu W, Morse Iii HC) Int J Mol Sci 2012;13(5):6204-6219       27 Citations
1Polycomb repressive complex 2 is required for MLL-AF9 leukemia. (Neff T, Sinha AU, Kluk MJ, Zhu N, Khattab MH, Stein L, Xie H, Orkin SH, Armstrong SA) Proc Natl Acad Sci U S A 2012 Mar 27;109(13):5028-33       181 Citations
1Chromatin-modifying enzymes as modulators of reprogramming. (Onder TT, Kara N, Cherry A, Sinha AU, Zhu N, Bernt KM, Cahan P, Marcarci BO, Unternaehrer J, Gupta PB, Lander ES, Armstrong SA, Daley GQ) Nature 2012 Mar 04;483(7391):598-602       527 Citations
1Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia. (LeGrand J, Park ES, Wang H, Gupta S, Owens JD Jr, Nelson PJ, DuBois W, Bair T, Janz S, Mushinski JF) Blood 2012 Jan 26;119(4):1018-28       5 Citations
1A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance. (Miller TW, Balko JM, Ghazoui Z, Dunbier A, Anderson H, Dowsett M, González-Angulo AM, Mills GB, Miller WR, Wu H, Shyr Y, Arteaga CL) Clin Cancer Res 2011 Apr 01;17(7):2024-34       81 Citations
1Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. (Li Y, Zhang Q, Yin X, Yang W, Du Y, Hou P, Ge J, Liu C, Zhang W, Zhang X, Wu Y, Li H, Liu K, Wu C, Song Z, Zhao Y, Shi Y, Deng H) Cell Res 2011 Jan;21(1):196-204       277 Citations
1B-cell activating factor and v-Myc myelocytomatosis viral oncogene homolog (c-Myc) influence progression of chronic lymphocytic leukemia. (Zhang W, Kater AP, Widhopf GF 2nd, Chuang HY, Enzler T, James DF, Poustovoitov M, Tseng PH, Janz S, Hoh C, Herschman H, Karin M, Kipps TJ) Proc Natl Acad Sci U S A 2010 Nov 02;107(44):18956-60       56 Citations
1Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms. (Zingone A, Cultraro CM, Shin DM, Bean CM, Morse HC 3rd, Janz S, Kuehl WM) Leukemia 2010 Jun;24(6):1171-8       20 Citations
1Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. (Zhang L, Ren X, Alt E, Bai X, Huang S, Xu Z, Lynch PM, Moyer MP, Wen XF, Wu X) Nature 2010 Apr 15;464(7291):1058-61       124 Citations
3Follicular lymphoma transformation to dual translocated Burkitt-like lymphoma: improved disease control associated with radiation therapy. (Parker SM, Olteanu H, VanTuinen P, Lawton CA, Schultz CJ, Christians KK, Fenske TS) Int J Hematol 2009 Dec;90(5):616-622       10 Citations
1N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. (Cotterman R, Jin VX, Krig SR, Lemen JM, Wey A, Farnham PJ, Knoepfler PS) Cancer Res 2008 Dec 01;68(23):9654-62       108 Citations
1Deregulation of c-Myc Confers distinct survival requirements for memory B cells, plasma cells, and their progenitors. (Khuda SE, Loo WM, Janz S, Van Ness B, Erickson LD) J Immunol 2008 Dec 01;181(11):7537-49       22 Citations
1Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding. (Chahdi A, Sorokin A) Mol Cell Biol 2008 Mar;28(5):1679-87       40 Citations
1CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. (Opavsky R, Wang SH, Trikha P, Raval A, Huang Y, Wu YZ, Rodriguez B, Keller B, Liyanarachchi S, Wei G, Davuluri RV, Weinstein M, Felsher D, Ostrowski M, Leone G, Plass C) PLoS Genet 2007 Sep;3(9):1757-69       37 Citations
1Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis. (Opavsky R, Tsai SY, Guimond M, Arora A, Opavska J, Becknell B, Kaufmann M, Walton NA, Stephens JA, Fernandez SA, Muthusamy N, Felsher DW, Porcu P, Caligiuri MA, Leone G) Proc Natl Acad Sci U S A 2007 Sep 25;104(39):15400-5       50 Citations
1In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 3' regulatory region induces MYC expression at the immature stage of B cell development. (Yan Y, Park SS, Janz S, Eckhardt LA) Genes Chromosomes Cancer 2007 Oct;46(10):950-9       16 Citations
1Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link. (Zada AA, Pulikkan JA, Bararia D, Geletu M, Trivedi AK, Balkhi MY, Hiddemann WD, Tenen DG, Behre HM, Behre G) Leukemia 2006 Dec;20(12):2137-46       27 Citations
1Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis. (Wen R, Chen Y, Bai L, Fu G, Schuman J, Dai X, Zeng H, Yang C, Stephan RP, Cleveland JL, Wang D) Mol Cell Biol 2006 Dec;26(24):9364-76       29 Citations
1CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms. (Han SS, Peng L, Chung ST, DuBois W, Maeng SH, Shaffer AL, Sporn MB, Janz S) Mol Cancer 2006 Jun 07;5:22       15 Citations
1Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1. (Han SS, Shaffer AL, Peng L, Chung ST, Lim JH, Maeng S, Kim JS, McNeil N, Ried T, Staudt LM, Janz S) Mol Cancer 2005 Nov 09;4:40       6 Citations
1Uncovering MYC's full oncogenic potential in the hematopoietic system. (Janz S) Oncogene 2005 May 19;24(22):3541-3       8 Citations
1Location of Myc, Igh, and Igk on Robertsonian fusion chromosomes is inconsequential for Myc translocations and plasmacytoma development in mice, but Rb(6.15)-carrying tumors prefer Igk-Myc inversions over translocations. (Silva S, Wiener F, Klein G, Janz S) Genes Chromosomes Cancer 2005 Apr;42(4):416-26       7 Citations
1Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice. (Cheung WC, Kim JS, Linden M, Peng L, Van Ness B, Polakiewicz RD, Janz S) J Clin Invest 2004 Jun;113(12):1763-73       94 Citations
2Expression of p53, c-Myc, or Bcl-6 suggests a poor prognosis in primary central nervous system diffuse large B-cell lymphoma among immunocompetent individuals. (Chang CC, Kampalath B, Schultz C, Bunyi-Teopengco E, Logan B, Eshoa C, Dincer AP, Perkins SL) Arch Pathol Lab Med 2003 Feb;127(2):208-12       71 Citations
1Myc requires distinct E2F activities to induce S phase and apoptosis. (Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, Smith C, Nevins JR) Mol Cell 2001 Jul;8(1):105-13       209 Citations
1Large cell/anaplastic medulloblastomas and medullomyoblastomas: clinicopathological and genetic features. (Leonard JR, Cai DX, Rivet DJ, Kaufman BA, Park TS, Levy BK, Perry A) J Neurosurg 2001 Jul;95(1):82-8       90 Citations
1Burkitt lymphoma in the mouse. (Kovalchuk AL, Qi CF, Torrey TA, Taddesse-Heath L, Feigenbaum L, Park SS, Gerbitz A, Klobeck G, Hoertnagel K, Polack A, Bornkamm GW, Janz S, Morse HC 3rd) J Exp Med 2000 Oct 16;192(8):1183-90       182 Citations
1Chromosomes 1 and 5 harbor plasmacytoma progressor genes in mice. (Coleman AE, Ried T, Janz S) Genes Chromosomes Cancer 2000 Sep;29(1):70-4       11 Citations
1Complex transcriptional regulatory mechanisms control expression of the E2F3 locus. (Adams MR, Sears R, Nuckolls F, Leone G, Nevins JR) Mol Cell Biol 2000 May;20(10):3633-9       115 Citations
1Ras enhances Myc protein stability. (Sears R, Leone G, DeGregori J, Nevins JR) Mol Cell 1999 Feb;3(2):169-79       388 Citations
1Follicular large cell lymphoma with immunoblastic features in a child with Wiskott-Aldrich syndrome: an unusual immunodeficiency-related neoplasm not associated with Epstein-Barr virus. (Kroft SH, Finn WG, Singleton TP, Ross CW, Sheldon S, Schnitzer B) Am J Clin Pathol 1998 Jul;110(1):95-9       19 Citations
1Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. (Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR) Nature 1997 May 22;387(6631):422-6       406 Citations
1Interaction of the bHLH-zip domain of c-Myc with H1-type peptides. Characterization of helicity in the H1 peptides by NMR. (Draeger LJ, Mullen GP) J Biol Chem 1994 Jan 21;269(3):1785-93       45 Citations