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7 | RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. (George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P) Cell Rep 2021 Nov 02;37(5):109934 30 Citations |
3 | Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia. (Gao X, Qin S, Wu Y, Chu C, Jiang B, Johnson RH, Kuang D, Zhang J, Wang X, Mehta A, Tew KD, Leone GW, Yu XZ, Wang H) J Clin Invest 2021 Aug 16;131(16) 21 Citations |
1 | Generation of Human iPSCs by Protein Reprogramming and Stimulation of TLR3 Signaling. (Liu C, Ameen M, Himmati S, Thomas D, Sayed N) Methods Mol Biol 2021;2239:153-162 2 Citations |
1 | Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation. (Meyer AE, Furumo Q, Stelloh C, Minella AC, Rao S) Neoplasia 2020 Nov;22(11):644-658 11 Citations |
1 | Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice. (Wen Z, Rajagopalan A, Flietner ED, Yun G, Chesi M, Furumo Q, Burns RT, Papadas A, Ranheim EA, Pagenkopf AC, Morrow ZT, Finn R, Zhou Y, Li S, You X, Jensen J, Yu M, Cicala A, Menting J, Mitsiades CS, Callander NS, Bergsagel PL, Wang D, Asimakopoulos F, Zhang J) Blood 2021 Jan 07;137(1):61-74 16 Citations |
1 | Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes. (Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin CM, Alontaga AY, McDaniel JM, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence HR, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha AM, Cleveland JL, Epling-Burnette PK) Blood 2020 Aug 13;136(7):857-870 15 Citations |
1 | MYC needs MNT to drive B cells over the edge. (Janz S) Blood 2020 Mar 26;135(13):977-978 1 Citation |
1 | CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia. (Pulikkan JA, Hegde M, Ahmad HM, Belaghzal H, Illendula A, Yu J, O'Hagan K, Ou J, Muller-Tidow C, Wolfe SA, Zhu LJ, Dekker J, Bushweller JH, Castilla LH) Cell 2018 Jun 28;174(1):172-186.e21 52 Citations |
1 | Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. (Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H) Sci Adv 2018 Jan;4(1):eaar5701 30 Citations |
1 | RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia. (Choi A, Illendula A, Pulikkan JA, Roderick JE, Tesell J, Yu J, Hermance N, Zhu LJ, Castilla LH, Bushweller JH, Kelliher MA) Blood 2017 Oct 12;130(15):1722-1733 53 Citations |
1 | Outcomes of Patients With Double-Hit Lymphoma Who Achieve First Complete Remission. (Landsburg DJ, Falkiewicz MK, Maly J, Blum KA, Howlett C, Feldman T, Mato AR, Hill BT, Li S, Medeiros LJ, Torka P, Hernandez-Ilizaliturri F, Reddy NM, Singavi A, Fenske TS, Chavez JC, Kaplan JB, Behdad A, Petrich AM, Bast MA, Vose JM, Olszewski AJ, Costa C, Lansigan F, Gerson JN, Barta SK, Calzada O, Cohen JB, Lue JK, Amengual JE, Rivera X, Persky DO, Peace DJ, Nathan S, Cassaday RD) J Clin Oncol 2017 Jul 10;35(20):2260-2267 124 Citations |
1 | FX11 inhibits aerobic glycolysis and growth of neuroblastoma cells. (Rellinger EJ, Craig BT, Alvarez AL, Dusek HL, Kim KW, Qiao J, Chung DH) Surgery 2017 Mar;161(3):747-752 28 Citations |
1 | PIAS1 Promotes Lymphomagenesis through MYC Upregulation. (Rabellino A, Melegari M, Tompkins VS, Chen W, Van Ness BG, Teruya-Feldstein J, Conacci-Sorrell M, Janz S, Scaglioni PP) Cell Rep 2016 Jun 07;15(10):2266-2278 36 Citations |
3 | The lncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis. (Iden M, Fye S, Li K, Chowdhury T, Ramchandran R, Rader JS) PLoS One 2016;11(5):e0156274 137 Citations |
1 | KSHV-encoded vIL-6 collaborates with deregulated c-Myc to drive plasmablastic neoplasms in mice. (Rosean TR, Holman CJ, Tompkins VS, Jing X, Krasowski MD, Rose-John S, Janz S) Blood Cancer J 2016 Feb 26;6(2):e398 16 Citations |
1 | Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice. (Tang X, Liu H, Srivastava A, Pécot T, Chen Z, Wang Q, Huang K, Sáenz-Robles MT, Cantalupo P, Pipas J, Leone G) Sci Data 2016 Feb 16;3:160008 5 Citations |
2 | Wnt/β-Catenin Signaling Activation beyond Robust Nuclear β-Catenin Accumulation in Nondysplastic Barrett's Esophagus: Regulation via Dickkopf-1. (Lyros O, Rafiee P, Nie L, Medda R, Jovanovic N, Otterson MF, Behmaram B, Gockel I, Mackinnon A, Shaker R) Neoplasia 2015 Jul;17(7):598-611 16 Citations |
1 | Targeting c-MYC in Platinum-Resistant Ovarian Cancer. (Reyes-González JM, Armaiz-Peña GN, Mangala LS, Valiyeva F, Ivan C, Pradeep S, Echevarría-Vargas IM, Rivera-Reyes A, Sood AK, Vivas-Mejía PE) Mol Cancer Ther 2015 Oct;14(10):2260-9 95 Citations |
1 | Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. (Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, Sáenz-Robles MT, Cantalupo P, Pipas JM, Leone G) Nat Cell Biol 2015 Aug;17(8):1036-48 56 Citations |
1 | A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma. (Wang F, Remke M, Bhat K, Wong ET, Zhou S, Ramaswamy V, Dubuc A, Fonkem E, Salem S, Zhang H, Hsieh TC, O'Rourke ST, Wu L, Li DW, Hawkins C, Kohane IS, Wu JM, Wu M, Taylor MD, Wu E) Oncotarget 2015 Feb 20;6(5):2709-24 17 Citations |
1 | Silencing of CDC42 inhibits neuroblastoma cell proliferation and transformation. (Lee S, Craig BT, Romain CV, Qiao J, Chung DH) Cancer Lett 2014 Dec 28;355(2):210-6 21 Citations |
1 | CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. (Huang CH, Lujambio A, Zuber J, Tschaharganeh DF, Doran MG, Evans MJ, Kitzing T, Zhu N, de Stanchina E, Sawyers CL, Armstrong SA, Lewis JS, Sherr CJ, Lowe SW) Genes Dev 2014 Aug 15;28(16):1800-14 154 Citations |
1 | Viral oncogene expression in the stem/progenitor cell compartment of the mouse intestine induces adenomatous polyps. (Sáenz Robles MT, Chong JL, Koivisto C, Trimboli A, Liu H, Leone G, Pipas JM) Mol Cancer Res 2014 Oct;12(10):1355-64 3 Citations |
1 | A new model of LMP1-MYC interaction in B cell lymphoma. (Ontiveros EP, Halwani A, Stunz LL, Kamberos N, Olivier AK, Janz S, Bishop GA) Leuk Lymphoma 2014 Dec;55(12):2917-23 5 Citations |
1 | Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery. (Guan X, Mack DL, Moreno CM, Strande JL, Mathieu J, Shi Y, Markert CD, Wang Z, Liu G, Lawlor MW, Moorefield EC, Jones TN, Fugate JA, Furth ME, Murry CE, Ruohola-Baker H, Zhang Y, Santana LF, Childers MK) Stem Cell Res 2014 Mar;12(2):467-80 102 Citations |
1 | Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis. (Wu L, de Bruin A, Wang H, Simmons T, Cleghorn W, Goldenberg LE, Sites E, Sandy A, Trimboli A, Fernandez SA, Eng C, Shapiro C, Leone G) Oncogene 2015 Jan 02;34(1):119-28 27 Citations |
1 | α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth. (Sengupta S, Weeraratne SD, Sun H, Phallen J, Rallapalli SK, Teider N, Kosaras B, Amani V, Pierre-Francois J, Tang Y, Nguyen B, Yu F, Schubert S, Balansay B, Mathios D, Lechpammer M, Archer TC, Tran P, Reimer RJ, Cook JM, Lim M, Jensen FE, Pomeroy SL, Cho YJ) Acta Neuropathol 2014 Apr;127(4):593-603 35 Citations |
1 | Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. (Zhou X, Fan LX, Sweeney WE Jr, Denu JM, Avner ED, Li X) J Clin Invest 2013 Jul;123(7):3084-98 117 Citations |
1 | Dual ALK and MYC rearrangements leading to an aggressive variant of anaplastic large cell lymphoma. (Liang X, Branchford B, Greffe B, McGavran L, Carstens B, Meltesen L, Albano EA, Quinones R, Cook B, Graham DK) J Pediatr Hematol Oncol 2013 Jul;35(5):e209-13 20 Citations |
1 | Piperlongumine inhibits proliferation and survival of Burkitt lymphoma in vitro. (Han SS, Son DJ, Yun H, Kamberos NL, Janz S) Leuk Res 2013 Feb;37(2):146-54 46 Citations |
1 | The feed-forward loop between YB-1 and MYC is essential for multiple myeloma cell survival. (Bommert KS, Effenberger M, Leich E, Küspert M, Murphy D, Langer C, Moll R, Janz S, Mottok A, Weissbach S, Rosenwald A, Bargou R, Bommert K) Leukemia 2013 Feb;27(2):441-50 44 Citations |
1 | Characterization of ARF-BP1/HUWE1 interactions with CTCF, MYC, ARF and p53 in MYC-driven B cell neoplasms. (Qi CF, Kim YS, Xiang S, Abdullaev Z, Torrey TA, Janz S, Kovalchuk AL, Sun J, Chen D, Cho WC, Gu W, Morse Iii HC) Int J Mol Sci 2012;13(5):6204-6219 27 Citations |
1 | Polycomb repressive complex 2 is required for MLL-AF9 leukemia. (Neff T, Sinha AU, Kluk MJ, Zhu N, Khattab MH, Stein L, Xie H, Orkin SH, Armstrong SA) Proc Natl Acad Sci U S A 2012 Mar 27;109(13):5028-33 181 Citations |
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1 | Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia. (LeGrand J, Park ES, Wang H, Gupta S, Owens JD Jr, Nelson PJ, DuBois W, Bair T, Janz S, Mushinski JF) Blood 2012 Jan 26;119(4):1018-28 5 Citations |
1 | A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance. (Miller TW, Balko JM, Ghazoui Z, Dunbier A, Anderson H, Dowsett M, González-Angulo AM, Mills GB, Miller WR, Wu H, Shyr Y, Arteaga CL) Clin Cancer Res 2011 Apr 01;17(7):2024-34 81 Citations |
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1 | Ectopic expression of wild-type FGFR3 cooperates with MYC to accelerate development of B-cell lineage neoplasms. (Zingone A, Cultraro CM, Shin DM, Bean CM, Morse HC 3rd, Janz S, Kuehl WM) Leukemia 2010 Jun;24(6):1171-8 20 Citations |
1 | Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. (Zhang L, Ren X, Alt E, Bai X, Huang S, Xu Z, Lynch PM, Moyer MP, Wen XF, Wu X) Nature 2010 Apr 15;464(7291):1058-61 124 Citations |
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1 | N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. (Cotterman R, Jin VX, Krig SR, Lemen JM, Wey A, Farnham PJ, Knoepfler PS) Cancer Res 2008 Dec 01;68(23):9654-62 108 Citations |
1 | Deregulation of c-Myc Confers distinct survival requirements for memory B cells, plasma cells, and their progenitors. (Khuda SE, Loo WM, Janz S, Van Ness B, Erickson LD) J Immunol 2008 Dec 01;181(11):7537-49 22 Citations |
1 | Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding. (Chahdi A, Sorokin A) Mol Cell Biol 2008 Mar;28(5):1679-87 40 Citations |
1 | CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells. (Opavsky R, Wang SH, Trikha P, Raval A, Huang Y, Wu YZ, Rodriguez B, Keller B, Liyanarachchi S, Wei G, Davuluri RV, Weinstein M, Felsher D, Ostrowski M, Leone G, Plass C) PLoS Genet 2007 Sep;3(9):1757-69 37 Citations |
1 | Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis. (Opavsky R, Tsai SY, Guimond M, Arora A, Opavska J, Becknell B, Kaufmann M, Walton NA, Stephens JA, Fernandez SA, Muthusamy N, Felsher DW, Porcu P, Caligiuri MA, Leone G) Proc Natl Acad Sci U S A 2007 Sep 25;104(39):15400-5 50 Citations |
1 | In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 3' regulatory region induces MYC expression at the immature stage of B cell development. (Yan Y, Park SS, Janz S, Eckhardt LA) Genes Chromosomes Cancer 2007 Oct;46(10):950-9 16 Citations |
1 | Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link. (Zada AA, Pulikkan JA, Bararia D, Geletu M, Trivedi AK, Balkhi MY, Hiddemann WD, Tenen DG, Behre HM, Behre G) Leukemia 2006 Dec;20(12):2137-46 27 Citations |
1 | Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis. (Wen R, Chen Y, Bai L, Fu G, Schuman J, Dai X, Zeng H, Yang C, Stephan RP, Cleveland JL, Wang D) Mol Cell Biol 2006 Dec;26(24):9364-76 29 Citations |
1 | CDDO-Imidazolide inhibits growth and survival of c-Myc-induced mouse B cell and plasma cell neoplasms. (Han SS, Peng L, Chung ST, DuBois W, Maeng SH, Shaffer AL, Sporn MB, Janz S) Mol Cancer 2006 Jun 07;5:22 15 Citations |
1 | Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1. (Han SS, Shaffer AL, Peng L, Chung ST, Lim JH, Maeng S, Kim JS, McNeil N, Ried T, Staudt LM, Janz S) Mol Cancer 2005 Nov 09;4:40 6 Citations |
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