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1 | Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth. (Nyquist MD, Ang LS, Corella A, Coleman IM, Meers MP, Christiani AJ, Pierce C, Janssens DH, Meade HE, Bose A, Brady L, Howard T, De Sarkar N, Frank SB, Dumpit RF, Dalton JT, Corey E, Plymate SR, Haffner MC, Mostaghel EA, Nelson PS) J Clin Invest 2021 May 17;131(10) 22 Citations |
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1 | Strain-specific joint invasion and colonization by Lyme disease spirochetes is promoted by outer surface protein C. (Lin YP, Tan X, Caine JA, Castellanos M, Chaconas G, Coburn J, Leong JM) PLoS Pathog 2020 May;16(5):e1008516 27 Citations |
1 | Preclinical Assessment with Clinical Validation of Selinexor with Gemcitabine and Nab-Paclitaxel for the Treatment of Pancreatic Ductal Adenocarcinoma. (Azmi AS, Khan HY, Muqbil I, Aboukameel A, Neggers JE, Daelemans D, Mahipal A, Dyson G, Kamgar M, Al-Hallak MN, Tesfaye A, Kim S, Shidham V, M Mohammad R, Philip PA) Clin Cancer Res 2020 Mar 15;26(6):1338-1348 26 Citations |
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1 | SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma. (Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, Van Buren G 2nd, McElhany AL, Fisher WE, Lonard DM, O'Malley BW, Wang J) Cancer Lett 2019 Feb 01;442:310-319 19 Citations |
1 | Human mesenchymal stromal cells do not promote recurrence of soft tissue sarcomas in mouse xenografts after radiation and surgery. (Filomeno PA, Kim KP, Yoon N, Rashedi I, Dayan V, Kandel RA, Wang XH, Felizardo TC, Berinstein E, Jelveh S, Filomeno A, Medin JA, Ferguson PC, Keating A) Cytotherapy 2018 Aug;20(8):1001-1012 1 Citation |
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1 | P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts. (Dou C, Liu Z, Tu K, Zhang H, Chen C, Yaqoob U, Wang Y, Wen J, van Deursen J, Sicard D, Tschumperlin D, Zou H, Huang WC, Urrutia R, Shah VH, Kang N) Gastroenterology 2018 Jun;154(8):2209-2221.e14 134 Citations |
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1 | Cancer stemness in bone marrow micrometastases of human breast cancer. (Kuo MC, Kothari AN, Kuo PC, Mi Z) Surgery 2018 Feb;163(2):330-335 16 Citations |
1 | Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer. (Hampsch RA, Shee K, Bates D, Lewis LD, Désiré L, Leblond B, Demidenko E, Stefan K, Huang YH, Miller TW) Oncotarget 2017 Mar 28;8(13):21806-21817 30 Citations |
1 | Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation. (Wu Y, Wang Y, Lin Y, Liu Y, Wang Y, Jia J, Singh P, Chi YI, Wang C, Dong C, Li W, Tao M, Napier D, Shi Q, Deng J, Evers BM, Zhou BP) Nat Commun 2017 Feb 15;8:14228 104 Citations |
1 | CD82 Is a Marker for Prospective Isolation of Human Muscle Satellite Cells and Is Linked to Muscular Dystrophies. (Alexander MS, Rozkalne A, Colletta A, Spinazzola JM, Johnson S, Rahimov F, Meng H, Lawlor MW, Estrella E, Kunkel LM, Gussoni E) Cell Stem Cell 2016 Dec 01;19(6):800-807 81 Citations |
1 | Relative distribution of Gb3 isoforms/analogs in NOD/SCID/Fabry mice tissues determined by tandem mass spectrometry. (Provençal P, Boutin M, Dworski S, Au B, Medin JA, Auray-Blais C) Bioanalysis 2016 Sep;8(17):1793-807 14 Citations |
1 | Heat shock protein 70-2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth. (Jagadish N, Parashar D, Gupta N, Agarwal S, Suri V, Kumar R, Suri V, Sadasukhi TC, Gupta A, Ansari AS, Lohiya NK, Suri A) BMC Cancer 2016 Jul 29;16:561 48 Citations |
1 | Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs. (Fox JM, Moynihan JR, Mott BT, Mazzone JR, Anders NM, Brown PA, Rudek MA, Liu JO, Arav-Boger R, Posner GH, Civin CI, Chen X) Oncotarget 2016 Feb 09;7(6):7268-79 25 Citations |
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1 | AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer. (Hong D, Kurzrock R, Kim Y, Woessner R, Younes A, Nemunaitis J, Fowler N, Zhou T, Schmidt J, Jo M, Lee SJ, Yamashita M, Hughes SG, Fayad L, Piha-Paul S, Nadella MV, Mohseni M, Lawson D, Reimer C, Blakey DC, Xiao X, Hsu J, Revenko A, Monia BP, MacLeod AR) Sci Transl Med 2015 Nov 18;7(314):314ra185 338 Citations |
1 | The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. (Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV) J Immunol 2015 Oct 01;195(7):3011-9 11 Citations |
1 | Evaluation of Bystander Cell Killing Effects in Suicide Gene Therapy of Cancer: Engineered Thymidylate Kinase (TMPK)/AZT Enzyme-Prodrug Axis. (Sato T, Neschadim A, Nakagawa R, Yanagisawa T, Medin JA) Methods Mol Biol 2015;1317:55-67 3 Citations |
1 | STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma. (Wu C, Molavi O, Zhang H, Gupta N, Alshareef A, Bone KM, Gopal K, Wu F, Lewis JT, Douglas DN, Kneteman NM, Lai R) Blood 2015 Jul 16;126(3):336-45 22 Citations |
1 | Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer. (Weber CE, Kothari AN, Wai PY, Li NY, Driver J, Zapf MA, Franzen CA, Gupta GN, Osipo C, Zlobin A, Syn WK, Zhang J, Kuo PC, Mi Z) Oncogene 2015 Sep 10;34(37):4821-33 159 Citations |
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1 | Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery. (Guan X, Mack DL, Moreno CM, Strande JL, Mathieu J, Shi Y, Markert CD, Wang Z, Liu G, Lawlor MW, Moorefield EC, Jones TN, Fugate JA, Furth ME, Murry CE, Ruohola-Baker H, Zhang Y, Santana LF, Childers MK) Stem Cell Res 2014 Mar;12(2):467-80 102 Citations |
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1 | Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia. (Bakchoul T, Greinacher A, Sachs UJ, Krautwurst A, Renz H, Harb H, Bein G, Newman PJ, Santoso S) Blood 2013 Jul 18;122(3):321-7 41 Citations |
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1 | From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. (Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE) Stem Cells Transl Med 2012 Jan;1(1):36-43 43 Citations |
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1 | The FGFR4-G388R single-nucleotide polymorphism alters pancreatic neuroendocrine tumor progression and response to mTOR inhibition therapy. (Serra S, Zheng L, Hassan M, Phan AT, Woodhouse LJ, Yao JC, Ezzat S, Asa SL) Cancer Res 2012 Nov 15;72(22):5683-91 45 Citations |
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1 | Lentivector transduction improves outcomes over transplantation of human HSCs alone in NOD/SCID/Fabry mice. (Pacienza N, Yoshimitsu M, Mizue N, Au BC, Wang JC, Fan X, Takenaka T, Medin JA) Mol Ther 2012 Jul;20(7):1454-61 24 Citations |
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