| 1 | Deciphering RNA G-quadruplex function during the early steps of HIV-1 infection. (Amrane S, Jaubert C, Bedrat A, Rundstadler T, Recordon-Pinson P, Aknin C, Guédin A, De Rache A, Bartolucci L, Diene I, Lemoine F, Gascuel O, Pratviel G, Mergny JL, Andreola ML) Nucleic Acids Res 2022 Nov 28;50(21):12328-12343 21 Citations |
| 1 | Evolutionary Conservation of Structural and Functional Coupling between the BRM AT-Hook and Bromodomain. (Lupo BE, Chu P, Harms MJ, Morrison EA, Musselman CA) J Mol Biol 2021 Jul 09;433(14):166845 6 Citations |
| 2 | Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function. (Duan J, Li J, Chen GL, Ge Y, Liu J, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J, Xue C, Liang B, Zhu L, Liu W, Zhang C, Tian XL, Wang J, Clapham DE, Zeng B, Li Z, Zhang J) Sci Adv 2019 Jul;5(7):eaaw7935 91 Citations |
| 1 | Role of Conserved Histidine and Serine in the HCXXXXXRS Motif of Human Dual-Specificity Phosphatase 5. (Gupta A, Brahmbhatt J, Syrlybaeva R, Bodnar C, Bodnar N, Bongard R, Pokkuluri PR, Sem DS, Ramchandran R, Rathore R, Talipov MR) J Chem Inf Model 2019 Apr 22;59(4):1563-1574 2 Citations |
| 1 | RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand. (Jaubert C, Bedrat A, Bartolucci L, Di Primo C, Ventura M, Mergny JL, Amrane S, Andreola ML) Sci Rep 2018 May 25;8(1):8120 37 Citations |
| 1 | Characterization of the pixB gene in Xenorhabdus nematophila and discovery of a new gene family. (Lucas J, Goetsch M, Fischer M, Forst S) Microbiology (Reading) 2018 Apr;164(4):495-508 3 Citations |
| 1 | Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202. (Gregory MC, Mak PJ, Khatri Y, Kincaid JR, Sligar SG) Biochemistry 2018 Feb 06;57(5):764-771 12 Citations |
| 1 | Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat. (Martín-Gálvez D, Dunoyer de Segonzac D, Ma MCJ, Kwitek AE, Thybert D, Flicek P) BMC Genomics 2017 Dec 22;18(1):986 3 Citations |
| 1 | A pivotal role for a conserved bulky residue at the α1-helix of the αI integrin domain in ligand binding. (Wang Z, Thinn AMM, Zhu J) J Biol Chem 2017 Dec 15;292(50):20756-20768 9 Citations |
| 2 | Modulators of Enterococcus faecalis Cell Envelope Integrity and Antimicrobial Resistance Influence Stable Colonization of the Mammalian Gastrointestinal Tract. (Banla IL, Kommineni S, Hayward M, Rodrigues M, Palmer KL, Salzman NH, Kristich CJ) Infect Immun 2018 Jan;86(1) 25 Citations |
| 1 | Mutations of conserved non-coding elements of PITX2 in patients with ocular dysgenesis and developmental glaucoma. (Protas ME, Weh E, Footz T, Kasberger J, Baraban SC, Levin AV, Katz LJ, Ritch R, Walter MA, Semina EV, Gould DB) Hum Mol Genet 2017 Sep 15;26(18):3630-3638 32 Citations |
| 1 | Editorial: Crossing the divide: a novel Cd8 enhancer with activity in CTLs and CD8αα+ dendritic cells. (Jeschke JC, Williams CB) J Leukoc Biol 2015 Apr;97(4):623-5 1 Citation |
| 1 | Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics. (Paulus JD, Link BA) PLoS One 2014;9(10):e109922 22 Citations |
| 1 | The solution structure of the forkhead box-O DNA binding domain of Brugia malayi DAF-16a. (Casper SK, Schoeller SJ, Zgoba DM, Phillips AJ, Morien TJ, Chaffee GR, Sackett PC, Peterson FC, Crossgrove K, Veldkamp CT) Proteins 2014 Dec;82(12):3490-6 4 Citations |
| 2 | Evidence supporting the existence of a NUPR1-like family of helix-loop-helix chromatin proteins related to, yet distinct from, AT hook-containing HMG proteins. (Urrutia R, Velez G, Lin M, Lomberk G, Neira JL, Iovanna J) J Mol Model 2014 Aug;20(8):2357 18 Citations |
| 1 | Rhythmic expression of cytochrome P450 epoxygenases CYP4x1 and CYP2c11 in the rat brain and vasculature. (Carver KA, Lourim D, Tryba AK, Harder DR) Am J Physiol Cell Physiol 2014 Dec 01;307(11):C989-98 54 Citations |
| 1 | TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy. (Theis JL, Zimmermann MT, Larsen BT, Rybakova IN, Long PA, Evans JM, Middha S, de Andrade M, Moss RL, Wieben ED, Michels VV, Olson TM) Hum Mol Genet 2014 Nov 01;23(21):5793-804 51 Citations |
| 1 | Human pegivirus RNA is found in multiple blood mononuclear cells in vivo and serum-derived viral RNA-containing particles are infectious in vitro. (Chivero ET, Bhattarai N, Rydze RT, Winters MA, Holodniy M, Stapleton JT) J Gen Virol 2014 Jun;95(Pt 6):1307-1319 73 Citations |
| 1 | A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation. (Boccuto L, Aoki K, Flanagan-Steet H, Chen CF, Fan X, Bartel F, Petukh M, Pittman A, Saul R, Chaubey A, Alexov E, Tiemeyer M, Steet R, Schwartz CE) Hum Mol Genet 2014 Jan 15;23(2):418-33 156 Citations |
| 3 | Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young. (Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R) J Biol Chem 2013 Jun 14;288(24):17745-58 30 Citations |
| 1 | The structure of allophanate hydrolase from Granulibacter bethesdensis provides insights into substrate specificity in the amidase signature family. (Lin Y, St Maurice M) Biochemistry 2013 Jan 29;52(4):690-700 16 Citations |
| 1 | Solution structure of the cold-shock-like protein from Rickettsia rickettsii. (Gerarden KP, Fuchs AM, Koch JM, Mueller MM, Graupner DR, O'Rorke JT, Frost CD, Heinen HA, Lackner ER, Schoeller SJ, House PG, Peterson FC, Veldkamp CT) Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Nov 01;68(Pt 11):1284-8 2 Citations |
| 1 | Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. (Santos JS, Asmar-Rovira GA, Han GW, Liu W, Syeda R, Cherezov V, Baker KA, Stevens RC, Montal M) J Biol Chem 2012 Dec 14;287(51):43063-70 23 Citations |
| 1 | Analysis of FOXD3 sequence variation in human ocular disease. (Kloss BA, Reis LM, Brémond-Gignac D, Glaser T, Semina EV) Mol Vis 2012;18:1740-9 16 Citations |
| 1 | Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis. (Fairman JW, Dautin N, Wojtowicz D, Liu W, Noinaj N, Barnard TJ, Udho E, Przytycka TM, Cherezov V, Buchanan SK) Structure 2012 Jul 03;20(7):1233-43 84 Citations |
| 1 | Comparative analysis of P2-type remnant prophage loci in Xenorhabdus bovienii and Xenorhabdus nematophila required for xenorhabdicin production. (Morales-Soto N, Gaudriault S, Ogier JC, Thappeta KR, Forst S) FEMS Microbiol Lett 2012 Aug;333(1):69-76 25 Citations |
| 2 | The glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates. (Castonguay AC, Lasanajak Y, Song X, Olson LJ, Cummings RD, Smith DF, Dahms NM) Glycobiology 2012 Jul;22(7):983-96 20 Citations |
| 1 | Solution structure of CCL21 and identification of a putative CCR7 binding site. (Love M, Sandberg JL, Ziarek JJ, Gerarden KP, Rode RR, Jensen DR, McCaslin DR, Peterson FC, Veldkamp CT) Biochemistry 2012 Jan 24;51(3):733-5 41 Citations |
| 1 | Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension. (Maloney JP, Stearman RS, Bull TM, Calabrese DW, Tripp-Addison ML, Wick MJ, Broeckel U, Robbins IM, Wheeler LA, Cogan JD, Loyd JE) Am J Physiol Lung Cell Mol Physiol 2012 Mar 15;302(6):L541-54 41 Citations |
| 2 | A conformational switch in the CRIB-PDZ module of Par-6. (Whitney DS, Peterson FC, Volkman BF) Structure 2011 Nov 09;19(11):1711-22 21 Citations |
| 1 | VSX2 mutations in autosomal recessive microphthalmia. (Reis LM, Khan A, Kariminejad A, Ebadi F, Tyler RC, Semina EV) Mol Vis 2011;17:2527-32 35 Citations |
| 2 | Effects of the L511P and D512G mutations on the Escherichia coli ABC transporter MsbA. (Schultz KM, Merten JA, Klug CS) Biochemistry 2011 Apr 05;50(13):2594-602 16 Citations |
| 1 | FOXE3 plays a significant role in autosomal recessive microphthalmia. (Reis LM, Tyler RC, Schneider A, Bardakjian T, Stoler JM, Melancon SB, Semina EV) Am J Med Genet A 2010 Mar;152A(3):582-90 56 Citations |
| 1 | Transcriptional regulatory regions of gap43 needed in developing and regenerating retinal ganglion cells. (Kusik BW, Hammond DR, Udvadia AJ) Dev Dyn 2010 Feb;239(2):482-95 34 Citations |
| 1 | Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36. (Means TK, Mylonakis E, Tampakakis E, Colvin RA, Seung E, Puckett L, Tai MF, Stewart CR, Pukkila-Worley R, Hickman SE, Moore KJ, Calderwood SB, Hacohen N, Luster AD, El Khoury J) J Exp Med 2009 Mar 16;206(3):637-53 208 Citations |
| 1 | Functionally important ATP binding and hydrolysis sites in Escherichia coli MsbA. (Westfahl KM, Merten JA, Buchaklian AH, Klug CS) Biochemistry 2008 Dec 30;47(52):13878-86 27 Citations |
| 1 | GATA4 sequence variants in patients with congenital heart disease. (Tomita-Mitchell A, Maslen CL, Morris CD, Garg V, Goldmuntz E) J Med Genet 2007 Dec;44(12):779-83 190 Citations |
| 1 | Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants. (Piana S, Laio A, Marinelli F, Van Troys M, Bourry D, Ampe C, Martins JC) J Mol Biol 2008 Jan 11;375(2):460-70 44 Citations |
| 1 | Mapping the specific cytoprotective interaction of humanin with the pro-apoptotic protein bid. (Choi J, Zhai D, Zhou X, Satterthwait A, Reed JC, Marassi FM) Chem Biol Drug Des 2007 Nov;70(5):383-92 20 Citations |
| 1 | Cloning and characterization of canine PAX6 and evaluation as a candidate gene in a canine model of aniridia. (Hunter LS, Sidjanin DJ, Hijar MV, Johnson JL, Kirkness E, Acland GM, Aguirre GD) Mol Vis 2007 Mar 26;13:431-42 3 Citations |
| 1 | Structural characterization of mumps virus fusion protein core. (Liu Y, Xu Y, Lou Z, Zhu J, Hu X, Gao GF, Qiu B, Rao Z, Tien P) Biochem Biophys Res Commun 2006 Sep 29;348(3):916-22 15 Citations |
| 1 | Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2. (Subramanian VS, Marchant JS, Said HM) Am J Physiol Cell Physiol 2006 Nov;291(5):C851-9 73 Citations |
| 2 | Solution structure of Arabidopsis thaliana protein At5g39720.1, a member of the AIG2-like protein family. (Lytle BL, Peterson FC, Tyler EM, Newman CL, Vinarov DA, Markley JL, Volkman BF) Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 Jun 01;62(Pt 6):490-3 8 Citations |
| 1 | Genome-wide analysis of core promoter elements from conserved human and mouse orthologous pairs. (Jin VX, Singer GA, Agosto-Pérez FJ, Liyanarachchi S, Davuluri RV) BMC Bioinformatics 2006 Mar 07;7:114 66 Citations |
| 1 | The flagellar motility of Chlamydomonas pf25 mutant lacking an AKAP-binding protein is overtly sensitive to medium conditions. (Yang C, Yang P) Mol Biol Cell 2006 Jan;17(1):227-38 26 Citations |
| 1 | The NH2 terminus of RCK1 domain regulates Ca2+-dependent BK(Ca) channel gating. (Krishnamoorthy G, Shi J, Sept D, Cui J) J Gen Physiol 2005 Sep;126(3):227-41 29 Citations |
| 1 | PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha. (Dey M, Trieselmann B, Locke EG, Lu J, Cao C, Dar AC, Krishnamoorthy T, Dong J, Sicheri F, Dever TE) Mol Cell Biol 2005 Apr;25(8):3063-75 62 Citations |
| 1 | Homeodomain revisited: a lesson from disease-causing mutations. (Chi YI) Hum Genet 2005 May;116(6):433-44 65 Citations |
| 1 | Site-directed mutagenesis analysis of amino acids critical for activity of the type I signal peptidase of the archaeon Methanococcus voltae. (Bardy SL, Ng SY, Carnegie DS, Jarrell KF) J Bacteriol 2005 Feb;187(3):1188-91 24 Citations |
| 1 | OMGProm: a database of orthologous mammalian gene promoters. (Palaniswamy SK, Jin VX, Sun H, Davuluri RV) Bioinformatics 2005 Mar;21(6):835-6 17 Citations |
| 1 | Mutations in PITX2 may contribute to cases of omphalocele and VATER-like syndromes. (Katz LA, Schultz RE, Semina EV, Torfs CP, Krahn KN, Murray JC) Am J Med Genet A 2004 Oct 15;130A(3):277-83 22 Citations |
| 1 | PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators. (Lamba V, Yasuda K, Lamba JK, Assem M, Davila J, Strom S, Schuetz EG) Toxicol Appl Pharmacol 2004 Sep 15;199(3):251-65 194 Citations |
| 1 | Structural studies of apoptosis and ion transport regulatory proteins in membranes. (Franzin CM, Choi J, Zhai D, Reed JC, Marassi FM) Magn Reson Chem 2004 Feb;42(2):172-9 41 Citations |
| 1 | Two novel conserved motifs in the hepatitis C virus NS3 protein critical for helicase action. (Lam AM, Keeney D, Frick DN) J Biol Chem 2003 Nov 07;278(45):44514-24 57 Citations |
| 1 | Molecular cloning and sequencing of the human heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase from bone marrow culture. (Omasa T, Chen YG, Mantalaris A, Tsai YC, Wu JH) DNA Seq 2002 Jun;13(3):133-7 4 Citations |
| 1 | Iron-sulfur cluster biosynthesis. Kinetic analysis of [2Fe-2S] cluster transfer from holo ISU to apo Fd: role of redox chemistry and a conserved aspartate. (Wu SP, Wu G, Surerus KK, Cowan JA) Biochemistry 2002 Jul 16;41(28):8876-85 93 Citations |
| 1 | AA.AG@helix.ends: A:A and A:G base-pairs at the ends of 16 S and 23 S rRNA helices. (Elgavish T, Cannone JJ, Lee JC, Harvey SC, Gutell RR) J Mol Biol 2001 Jul 20;310(4):735-53 59 Citations |
| 1 | Genomic analysis of the histidine kinase family in bacteria and archaea. (Kim DJ, Forst S) Microbiology (Reading) 2001 May;147(Pt 5):1197-1212 128 Citations |
| 1 | Positional cloning of a novel gene on chromosome 16q causing Bardet-Biedl syndrome (BBS2). (Nishimura DY, Searby CC, Carmi R, Elbedour K, Van Maldergem L, Fulton AB, Lam BL, Powell BR, Swiderski RE, Bugge KE, Haider NB, Kwitek-Black AE, Ying L, Duhl DM, Gorman SW, Heon E, Iannaccone A, Bonneau D, Biesecker LG, Jacobson SG, Stone EM, Sheffield VC) Hum Mol Genet 2001 Apr 01;10(8):865-74 220 Citations |
| 1 | A winged helix protein from yeast Saccharomyces cerevisiae recognizes centromere sequences. (Myrich E, Shiyanova T, Liao X) Arch Biochem Biophys 2000 Mar 01;375(1):78-82 1 Citation |
| 1 | Residues of 14-3-3 zeta required for activation of exoenzyme S of Pseudomonas aeruginosa. (Zhang L, Wang H, Masters SC, Wang B, Barbieri JT, Fu H) Biochemistry 1999 Sep 14;38(37):12159-64 38 Citations |
| 1 | The 5'-untranslated region of GM-CSF mRNA suppresses translational repression mediated by the 3' adenosine-uridine-rich element and the poly(A) tail. (Jarzembowski JA, Rajagopalan LE, Shin HC, Malter JS) Nucleic Acids Res 1999 Sep 15;27(18):3660-6 13 Citations |
| 1 | Identification of a conserved N-terminal sequence involved in transmembrane signal transduction in EnvZ. (Waukau J, Forst S) J Bacteriol 1999 Sep;181(17):5534-8 10 Citations |
| 1 | A new human homeobox gene OGI2X is a member of the most conserved homeobox gene family and is expressed during heart development in mouse. (Semina EV, Reiter RS, Murray JC) Hum Mol Genet 1998 Mar;7(3):415-22 48 Citations |
| 1 | Conserved enhancer elements in human and mouse renin genes have different transcriptional effects in As4.1 cells. (Yan Y, Jones CA, Sigmund CD, Gross KW, Catanzaro DF) Circ Res 1997 Oct;81(4):558-66 52 Citations |
| 1 | Detection of adenovirus DNA in peripheral blood mononuclear cells by polymerase chain reaction assay. (Flomenberg P, Gutierrez E, Piaskowski V, Casper JT) J Med Virol 1997 Mar;51(3):182-8 49 Citations |
| 1 | The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes. (Bessman MJ, Frick DN, O'Handley SF) J Biol Chem 1996 Oct 11;271(41):25059-62 628 Citations |
| 1 | The role of Glu 57 in the mechanism of the Escherichia coli MutT enzyme by mutagenesis and heteronuclear NMR. (Lin J, Abeygunawardana C, Frick DN, Bessman MJ, Mildvan AS) Biochemistry 1996 May 28;35(21):6715-26 52 Citations |
| 1 | Insulin-like growth factor II/cation-independent mannose 6-phosphate receptor and lysosomal enzyme recognition. (Dahms NM) Biochem Soc Trans 1996 Feb;24(1):136-41 38 Citations |
| 1 | Identification of a novel divergent calmodulin isoform from soybean which has differential ability to activate calmodulin-dependent enzymes. (Lee SH, Kim JC, Lee MS, Heo WD, Seo HY, Yoon HW, Hong JC, Lee SY, Bahk JD, Hwang I) J Biol Chem 1995 Sep 15;270(37):21806-12 127 Citations |
| 1 | Biochemical analysis of mutations at tyrosine-98 of the S1 subunit of pertussis toxin. (Xu Y, Barbieri JT) Biochemistry 1994 Feb 15;33(6):1573-9 |
| 1 | Interaction of the bHLH-zip domain of c-Myc with H1-type peptides. Characterization of helicity in the H1 peptides by NMR. (Draeger LJ, Mullen GP) J Biol Chem 1994 Jan 21;269(3):1785-93 51 Citations |
| 1 | Identification of a phosphorylation site and functional analysis of conserved aspartic acid residues of OmpR, a transcriptional activator for ompF and ompC in Escherichia coli. (Delgado J, Forst S, Harlocker S, Inouye M) Mol Microbiol 1993 Dec;10(5):1037-47 94 Citations |
| 1 | Molecular cloning of a cDNA encoding human histidase. (Suchi M, Harada N, Wada Y, Takagi Y) Biochim Biophys Acta 1993 Nov 16;1216(2):293-5 24 Citations |
| 1 | Biochemical analysis of mutant alleles of the vaccinia virus topoisomerase I carrying targeted substitutions in a highly conserved domain. (Klemperer N, Traktman P) J Biol Chem 1993 Jul 25;268(21):15887-99 28 Citations |
© 2026 Clinical & Translational Science Institute