| 1 | Deletion of Vβ3+CD4+ T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8+ T cells. (Ye C, Clements SA, Gu W, Geurts AM, Mathews CE, Serreze DV, Chen YG, Driver JP) Proc Natl Acad Sci U S A 2023 Dec 05;120(49):e2312039120 |
| 2 | Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer. (Kharel A, Shen J, Brown R, Chen Y, Nguyen C, Alson D, Bluemn T, Fan J, Gai K, Zhang B, Kudek M, Zhu N, Cui W) Cell Rep 2023 Jun 27;42(6):112649 3 Citations |
| 2 | Dysregulated Lymphocyte Antigen Receptor Signaling in Common Variable Immunodeficiency with Granulomatous Lymphocytic Interstitial Lung Disease. (Lui VG, Ghosh T, Rymaszewski A, Chen S, Baxter RM, Kong DS, Ghosh D, Routes JM, Verbsky JW, Hsieh EWY) J Clin Immunol 2023 Aug;43(6):1311-1325 1 Citation |
| 1 | Inflammatory CD4/CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology. (Hess NJ, Turicek DP, Riendeau J, McIlwain SJ, Contreras Guzman E, Nadiminti K, Hudson A, Callander NS, Skala MC, Gumperz JE, Hematti P, Capitini CM) Sci Adv 2023 Mar 24;9(12):eadf0567 6 Citations |
| 1 | Lymphocytic Choriomeningitis Virus Clone 13 Infection Results in CD8 T Cell-Mediated Host Mortality in Diacylglycerol Kinase α-Deficient Mice. (Kudek MR, Xin G, Alson D, Holzhauer S, Shen J, Kasmani MY, Riese M, Cui W) J Immunol 2023 May 01;210(9):1281-1291 |
| 1 | Pre-existing anti-factor VIII immunity alters therapeutic platelet-targeted factor VIII engraftment following busulfan conditioning through cytotoxic CD8 T cells. (Jing W, Baumgartner CK, Xue F, Schroeder JA, Shi Q) J Thromb Haemost 2023 Mar;21(3):488-498 1 Citation |
| 1 | Manufacture and Characterization of Good Manufacturing Practice-Compliant SARS-COV-2 Cytotoxic T Lymphocytes. (Chu Y, Milner J, Lamb M, Maryamchik E, Rigot O, Ayello J, Harrison L, Shaw R, Behbehani GK, Mardis ER, Miller K, Prakruthi Rao Venkata L, Chang H, Lee D, Rosenthal E, Kadauke S, Bunin N, Talano JA, Johnson B, Wang Y, Cairo MS) J Infect Dis 2023 Mar 28;227(6):788-799 |
| 1 | In situ vaccination with cowpea mosaic virus elicits systemic antitumor immunity and potentiates immune checkpoint blockade. (Mao C, Beiss V, Ho GW, Fields J, Steinmetz NF, Fiering S) J Immunother Cancer 2022 Dec;10(12) 9 Citations |
| 1 | Cell-Mediated Cytotoxicity in Lyme Arthritis. (Ordóñez D, Lochhead RB, Strle K, Pianta A, Arvikar S, Van Rhijn I, Stemmer-Rachamimov A, Steere AC) Arthritis Rheumatol 2023 May;75(5):782-793 2 Citations |
| 1 | Endothelial Rap1B mediates T-cell exclusion to promote tumor growth: a novel mechanism underlying vascular immunosuppression. (Sharma GP, Kosuru R, Lakshmikanthan S, Zheng S, Chen Y, Burns R, Xin G, Cui W, Chrzanowska M) Angiogenesis 2023 May;26(2):265-278 1 Citation |
| 2 | T cell-extrinsic IL-1 signaling controls long-term gammaherpesvirus infection by suppressing viral reactivation. (Sylvester PA, Corbett JA, Tarakanova VL) Virology 2022 Nov;576:134-140 1 Citation |
| 2 | S1P/S1PR1 signaling differentially regulates the allogeneic response of CD4 and CD8 T cells by modulating mitochondrial fission. (Tian L, Wu Y, Choi HJ, Sui X, Li X, Sofi MH, Kassir MF, Chen X, Mehrotra S, Ogretmen B, Yu XZ) Cell Mol Immunol 2022 Nov;19(11):1235-1250 10 Citations |
| 1 | Aberrant T-cell exhaustion in severe combined immunodeficiency survivors with poor T-cell reconstitution after transplantation. (Labrosse R, Boufaied I, Bourdin B, Gona S, Randolph HE, Logan BR, Bourbonnais S, Berthe C, Chan W, Buckley RH, Parrott RE, Cuvelier GDE, Kapoor N, Chandra S, Dávila Saldaña BJ, Eissa H, Goldman FD, Heimall J, O'Reilly R, Chaudhury S, Kolb EA, Shenoy S, Griffith LM, Pulsipher M, Kohn DB, Notarangelo LD, Pai SY, Cowan MJ, Dvorak CC, Haddad É, Puck JM, Barreiro LB, Decaluwe H) J Allergy Clin Immunol 2023 Jan;151(1):260-271 1 Citation |
| 1 | Autoreactive CD8 T cells in NOD mice exhibit phenotypic heterogeneity but restricted TCR gene usage. (Kasmani MY, Ciecko AE, Brown AK, Petrova G, Gorski J, Chen YG, Cui W) Life Sci Alliance 2022 Oct;5(10) 2 Citations |
| 1 | Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice. (Song Y, Bugada L, Li R, Hu H, Zhang L, Li C, Yuan H, Rajanayake KK, Truchan NA, Wen F, Gao W, Sun D) Sci Transl Med 2022 May 04;14(643):eabl3649 36 Citations |
| 1 | Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation. (Moustaki A, Crawford JC, Alli S, Fan Y, Boi S, Zamora AE, McDonald NMN, Wu G, Nakitandwe J, Newman S, Foy S, Silkov A, Thomas PG, Pappo A, Dyer MA, Stewart E, Federico S, Youngblood B) Sci Immunol 2022 Feb 04;7(68):eabf6136 5 Citations |
| 1 | Lymphocyte subset abnormalities in early severe scleroderma favor a Th2 phenotype and are not altered by prior immunosuppressive therapy. (Shah A, Storek J, Woolson R, Pinckney A, Keyes-Elstein L, Wallace PK, Sempowski GD, McSweeney P, Mayes MD, Crofford L, Csuka ME, Phillips K, Khanna D, Simms R, Ballen K, LeClercq S, Clair WS, Nixon AB, Nash R, Wener M, Brasington R, Silver R, Griffith LM, Furst DE, Goldmuntz E, Sullivan KM) Rheumatology (Oxford) 2022 Oct 06;61(10):4155-4162 7 Citations |
| 3 | Cytotoxic CD8-positive T-lymphocyte infiltration in the lungs as a histological pattern of SARS-CoV-2 pneumonitis. (Puzyrenko A, Felix JC, Ledeboer NA, Sun Y, Rui H, Sheinin Y) Pathology 2022 Jun;54(4):404-408 6 Citations |
| 1 | T cell receptor-targeted immunotherapeutics drive selective in vivo HIV- and CMV-specific T cell expansion in humanized mice. (Li M, Garforth SJ, O'Connor KE, Su H, Lee DM, Celikgil A, Chaparro RJ, Seidel RD, Jones RB, Arav-Boger R, Almo SC, Goldstein H) J Clin Invest 2021 Dec 01;131(23) 8 Citations |
| 3 | Self-Renewing Islet TCF1+ CD8 T Cells Undergo IL-27-Controlled Differentiation to Become TCF1- Terminal Effectors during the Progression of Type 1 Diabetes. (Ciecko AE, Schauder DM, Foda B, Petrova G, Kasmani MY, Burns R, Lin CW, Drobyski WR, Cui W, Chen YG) J Immunol 2021 Oct 15;207(8):1990-2004 13 Citations |
| 1 | DGKζ exerts greater control than DGKα over CD8+ T cell activity and tumor inhibition. (Gu J, Wang C, Cao C, Huang J, Holzhauer S, Desilva H, Wesley EM, Evans DB, Benci J, Wichroski M, Wee S, Riese MJ) Oncoimmunology 2021;10(1):1941566 6 Citations |
| 1 | Antitumor effects of iPSC-based cancer vaccine in pancreatic cancer. (Ouyang X, Liu Y, Zhou Y, Guo J, Wei TT, Liu C, Lee B, Chen B, Zhang A, Casey KM, Wang L, Kooreman NG, Habtezion A, Engleman EG, Wu JC) Stem Cell Reports 2021 Jun 08;16(6):1468-1477 24 Citations |
| 1 | E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation. (Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W) Proc Natl Acad Sci U S A 2021 Apr 20;118(16) 15 Citations |
| 3 | Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer. (Xin G, Chen Y, Topchyan P, Kasmani MY, Burns R, Volberding PJ, Wu X, Cohn A, Chen Y, Lin CW, Ho PC, Silverstein R, Dwinell MB, Cui W) Cancer Immunol Res 2021 Apr;9(4):454-469 20 Citations |
| 1 | STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function. (Wu Y, Tang CA, Mealer C, Bastian D, Hanief Sofi M, Tian L, Schutt S, Choi HJ, Ticer T, Zhang M, Sui X, Huang L, Mellor AL, Hu CA, Yu XZ) Cell Mol Immunol 2021 Mar;18(3):632-643 4 Citations |
| 1 | Estrogen receptor beta signaling in CD8+ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch. (Yuan B, Clark CA, Wu B, Yang J, Drerup JM, Li T, Jin VX, Hu Y, Curiel TJ, Li R) J Immunother Cancer 2021 Jan;9(1) 15 Citations |
| 3 | Kras-Deficient T Cells Attenuate Graft-versus-Host Disease but Retain Graft-versus-Leukemia Activity. (Luo L, Chen Y, Chen X, Zheng Y, Zhou V, Yu M, Burns R, Zhu W, Fu G, Felix JC, Hartley C, Damnernsawad A, Zhang J, Wen R, Drobyski WR, Gao C, Wang D) J Immunol 2020 Dec 15;205(12):3480-3490 3 Citations |
| 2 | Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease. (Yuan CY, Zhou V, Sauber G, Stollenwerk T, Komorowski R, López A, Tolón RM, Romero J, Hillard CJ, Drobyski WR) Blood 2021 Mar 04;137(9):1241-1255 11 Citations |
| 2 | CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation. (Shapiro MR, Yeh WI, Longfield JR, Gallagher J, Infante CM, Wellford S, Posgai AL, Atkinson MA, Campbell-Thompson M, Lieberman SM, Serreze DV, Geurts AM, Chen YG, Brusko TM) Front Immunol 2020;11:2180 16 Citations |
| 1 | Interferon Regulatory Factor 7 Attenuates Chronic Gammaherpesvirus Infection. (Johnson KE, Aurubin CA, Jondle CN, Lange PT, Tarakanova VL) J Virol 2020 Nov 23;94(24) 9 Citations |
| 1 | Concurrent Subcutaneous Panniculitis-like T-Cell Lymphoma and B-Cell Acute Lymphoblastic Leukemia in 2 Pediatric Patients. (Smith GA, Levinson AL, Galvin RT, Lalor LE, McCalmont T, Wang L, Geis MC, Odegaard K, Hupp M, Maguiness S, Turcotte LM, Cordoro KM, Hermiston ML) J Pediatr Hematol Oncol 2021 Aug 01;43(6):e791-e794 |
| 1 | Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer. (Axelrod ML, Nixon MJ, Gonzalez-Ericsson PI, Bergman RE, Pilkinton MA, McDonnell WJ, Sanchez V, Opalenik SR, Loi S, Zhou J, Mackay S, Rexer BN, Abramson VG, Jansen VM, Mallal S, Donaldson J, Tolaney SM, Krop IE, Garrido-Castro AC, Marotti JD, Shee K, Miller TW, Sanders ME, Mayer IA, Salgado R, Balko JM) Clin Cancer Res 2020 Nov 01;26(21):5668-5681 34 Citations |
| 1 | UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice. (Chen YG, Ciecko AE, Khaja S, Grzybowski M, Geurts AM, Lieberman SM) Sci Rep 2020 Jul 21;10(1):12019 9 Citations |
| 1 | Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes. (Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin CM, Alontaga AY, McDaniel JM, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence HR, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha AM, Cleveland JL, Epling-Burnette PK) Blood 2020 Aug 13;136(7):857-870 15 Citations |
| 1 | Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes. (Lee H, Lee YS, Harenda Q, Pietrzak S, Oktay HZ, Schreiber S, Liao Y, Sonthalia S, Ciecko AE, Chen YG, Keles S, Sridharan R, Engin F) Cell Metab 2020 Apr 07;31(4):822-836.e5 73 Citations |
| 1 | Vitamin C stabilizes CD8+ iTregs and enhances their therapeutic potential in controlling murine GVHD and leukemia relapse. (Iamsawat S, Tian L, Daenthanasanmak A, Wu Y, Nguyen HD, Bastian D, Yu XZ) Blood Adv 2019 Dec 23;3(24):4187-4201 14 Citations |
| 2 | Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation. (Ciecko AE, Foda B, Barr JY, Ramanathan S, Atkinson MA, Serreze DV, Geurts AM, Lieberman SM, Chen YG) Cell Rep 2019 Dec 03;29(10):3073-3086.e5 30 Citations |
| 2 | CXCR5+PD-1+ follicular helper CD8 T cells control B cell tolerance. (Chen Y, Yu M, Zheng Y, Fu G, Xin G, Zhu W, Luo L, Burns R, Li QZ, Dent AL, Zhu N, Cui W, Malherbe L, Wen R, Wang D) Nat Commun 2019 Sep 27;10(1):4415 56 Citations |
| 1 | Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses. (Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG) Sci Transl Med 2019 Jun 26;11(498) 63 Citations |
| 2 | Impact of T Cell Dose on Outcome of T Cell-Replete HLA-Matched Allogeneic Peripheral Blood Stem Cell Transplantation. (Saad A, Lamb L, Wang T, Hemmer MT, Spellman S, Couriel D, Alousi A, Pidala J, Abdel-Azim H, Agrawal V, Aljurf M, Beitinjaneh AM, Bhatt VR, Buchbinder D, Byrne M, Cahn JY, Cairo M, Castillo P, Chhabra S, Diaz MA, Farhan S, Floisand Y, Frangoul HA, Gadalla SM, Gajewski J, Gale RP, Gandhi M, Gergis U, Hamilton BK, Hematti P, Hildebrandt GC, Kamble RT, Kanate AS, Khandelwal P, Lazaryan A, MacMillan M, Marks DI, Martino R, Mehta PA, Nishihori T, Olsson RF, Patel SS, Qayed M, Rangarajan HG, Reshef R, Ringden O, Savani BN, Schouten HC, Schultz KR, Seo S, Shaffer BC, Solh M, Teshima T, Urbano-Ispizua A, Verdonck LF, Vij R, Waller EK, William B, Wirk B, Yared JA, Yu LC, Arora M, Hashmi S) Biol Blood Marrow Transplant 2019 Sep;25(9):1875-1883 12 Citations |
| 1 | Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8+ T-Cell Activation. (Wang Z, Vaughan TY, Zhu W, Chen Y, Fu G, Medrzycki M, Nishio H, Bunting ST, Hankey-Giblin PA, Nusrat A, Parkos CA, Wang D, Wen R, Bunting KD) Front Immunol 2019;10:486 11 Citations |
| 1 | LXR Alpha Restricts Gammaherpesvirus Reactivation from Latently Infected Peritoneal Cells. (Lange PT, Jondle CN, Darrah EJ, Johnson KE, Tarakanova VL) J Virol 2019 Mar 15;93(6) 16 Citations |
| 1 | Stabilization of Foxp3 by Targeting JAK2 Enhances Efficacy of CD8 Induced Regulatory T Cells in the Prevention of Graft-versus-Host Disease. (Iamsawat S, Daenthanasanmak A, Voss JH, Nguyen H, Bastian D, Liu C, Yu XZ) J Immunol 2018 Nov 01;201(9):2812-2823 25 Citations |
| 2 | A Hypermorphic Nfkbid Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in NOD Mice. (Presa M, Racine JJ, Dwyer JR, Lamont DJ, Ratiu JJ, Sarsani VK, Chen YG, Geurts A, Schmitz I, Stearns T, Allocco J, Chapman HD, Serreze DV) J Immunol 2018 Oct 01;201(7):1907-1917 11 Citations |
| 4 | Frontline Science: PECAM-1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells. (Newman DK, Fu G, McOlash L, Schauder D, Newman PJ, Cui W, Rao S, Johnson BD, Gershan JA, Riese MJ) J Leukoc Biol 2018 Nov;104(5):883-893 14 Citations |
| 1 | Bone Marrow-derived CD8+ T Cells From Pediatric Leukemia Patients Express PD1 and Expand Ex Vivo Following Induction Chemotherapy. (Palen K, Thakar M, Johnson BD, Gershan JA) J Pediatr Hematol Oncol 2019 Nov;41(8):648-652 2 Citations |
| 1 | Bim regulates the survival and suppressive capability of CD8+ FOXP3+ regulatory T cells during murine GVHD. (Agle K, Vincent BG, Piper C, Belle L, Zhou V, Shlomchik W, Serody JS, Drobyski WR) Blood 2018 Jul 26;132(4):435-447 31 Citations |
| 1 | Regulation of Bone Remodeling by Parathyroid Hormone. (Wein MN, Kronenberg HM) Cold Spring Harb Perspect Med 2018 Aug 01;8(8) 137 Citations |
| 1 | Blockade of BAFF Receptor BR3 on T Cells Enhances Their Activation and Cytotoxicity. (Bloom DD, Reshetylo S, Nytes C, Goodsett CT, Hematti P) J Immunother 2018 Jun;41(5):213-223 7 Citations |
| 2 | Closed-system manufacturing of CD19 and dual-targeted CD20/19 chimeric antigen receptor T cells using the CliniMACS Prodigy device at an academic medical center. (Zhu F, Shah N, Xu H, Schneider D, Orentas R, Dropulic B, Hari P, Keever-Taylor CA) Cytotherapy 2018 Mar;20(3):394-406 76 Citations |
| 1 | Formulation of the bivalent prostate cancer vaccine with surgifoam elicits antigen-specific effector T cells in PSA-transgenic mice. (Karan D) Vaccine 2017 Oct 13;35(43):5794-5798 7 Citations |
| 1 | PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer. (Kansy BA, Concha-Benavente F, Srivastava RM, Jie HB, Shayan G, Lei Y, Moskovitz J, Moy J, Li J, Brandau S, Lang S, Schmitt NC, Freeman GJ, Gooding WE, Clump DA, Ferris RL) Cancer Res 2017 Nov 15;77(22):6353-6364 147 Citations |
| 1 | Versican-Derived Matrikines Regulate Batf3-Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer. (Hope C, Emmerich PB, Papadas A, Pagenkopf A, Matkowskyj KA, Van De Hey DR, Payne SN, Clipson L, Callander NS, Hematti P, Miyamoto S, Johnson MG, Deming DA, Asimakopoulos F) J Immunol 2017 Sep 01;199(5):1933-1941 70 Citations |
| 1 | SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans. (Allen EK, Randolph AG, Bhangale T, Dogra P, Ohlson M, Oshansky CM, Zamora AE, Shannon JP, Finkelstein D, Dressen A, DeVincenzo J, Caniza M, Youngblood B, Rosenberger CM, Thomas PG) Nat Med 2017 Aug;23(8):975-983 134 Citations |
| 1 | B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection. (Darrah EJ, Kulinski JM, Mboko WP, Xin G, Malherbe LP, Gauld SB, Cui W, Tarakanova VL) J Virol 2017 Oct 01;91(19) 7 Citations |
| 1 | Adoptive cell therapy using PD-1+ myeloma-reactive T cells eliminates established myeloma in mice. (Jing W, Gershan JA, Blitzer GC, Palen K, Weber J, McOlash L, Riese M, Johnson BD) J Immunother Cancer 2017;5:51 22 Citations |
| 1 | Disseminated CD8-positive, CD30-positive cutaneous lymphoproliferative eruption with overlapping features of mycosis fungoides and primary cutaneous anaplastic large cell lymphoma following remote solitary lesional presentation. (Davick JJ, Mutgi KAJ, Wanat KA, Link BK, Liu V) J Cutan Pathol 2017 Aug;44(8):703-712 4 Citations |
| 1 | CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice. (Forsberg MH, Ciecko AE, Bednar KJ, Itoh A, Kachapati K, Ridgway WM, Chen YG) J Immunol 2017 May 15;198(10):3857-3868 16 Citations |
| 1 | Immune Microenvironment in Microsatellite-Instable Endometrial Cancers: Hereditary or Sporadic Origin Matters. (Pakish JB, Zhang Q, Chen Z, Liang H, Chisholm GB, Yuan Y, Mok SC, Broaddus RR, Lu KH, Yates MS) Clin Cancer Res 2017 Aug 01;23(15):4473-4481 95 Citations |
| 1 | Dual Specificity Phosphatase 5 Is Essential for T Cell Survival. (Kutty RG, Xin G, Schauder DM, Cossette SM, Bordas M, Cui W, Ramchandran R) PLoS One 2016;11(12):e0167246 15 Citations |
| 1 | Interferon-γ Limits Diabetogenic CD8+ T-Cell Effector Responses in Type 1 Diabetes. (Driver JP, Racine JJ, Ye C, Lamont DJ, Newby BN, Leeth CM, Chapman HD, Brusko TM, Chen YG, Mathews CE, Serreze DV) Diabetes 2017 Mar;66(3):710-721 24 Citations |
| 1 | Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes. (Semenkovich NP, Planer JD, Ahern PP, Griffin NW, Lin CY, Gordon JI) Proc Natl Acad Sci U S A 2016 Dec 20;113(51):14805-14810 31 Citations |
| 1 | Cell-Intrinsic Barriers of T Cell-Based Immunotherapy. (Ghoneim HE, Zamora AE, Thomas PG, Youngblood BA) Trends Mol Med 2016 Dec;22(12):1000-1011 53 Citations |
| 2 | Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression. (Belle L, Agle K, Zhou V, Yin-Yuan C, Komorowski R, Eastwood D, Logan B, Sun J, Ghilardi N, Cua D, Williams CB, Gaignage M, Marillier R, van Snick J, Drobyski WR) Blood 2016 Oct 20;128(16):2068-2082 34 Citations |
| 1 | Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease. (Cepero-Donates Y, Lacraz G, Ghobadi F, Rakotoarivelo V, Orkhis S, Mayhue M, Chen YG, Rola-Pleszczynski M, Menendez A, Ilangumaran S, Ramanathan S) Cytokine 2016 Jun;82:102-11 49 Citations |
| 1 | Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic. (Majchrzak K, Nelson MH, Bailey SR, Bowers JS, Yu XZ, Rubinstein MP, Himes RA, Paulos CM) Cancer Immunol Immunother 2016 Mar;65(3):247-59 33 Citations |
| 1 | Post-Treatment Controllers: Role in HIV "Cure" Research. (Cockerham LR, Hatano H, Deeks SG) Curr HIV/AIDS Rep 2016 Feb;13(1):1-9 24 Citations |
| 1 | Homeostasis of IL-15 dependent lymphocyte subsets in the liver. (Cepero-Donates Y, Rakotoarivelo V, Mayhue M, Ma A, Chen YG, Ramanathan S) Cytokine 2016 Jun;82:95-101 17 Citations |
| 1 | CD4+ and CD8+ T Cell Activation in Children with Hepatitis C. (Sheiko MA, Golden-Mason L, Giugliano S, Hurtado CW, Mack CL, Narkewicz MR, Rosen HR) J Pediatr 2016 Mar;170:142-8.e1 9 Citations |
| 2 | A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control. (Xin G, Schauder DM, Lainez B, Weinstein JS, Dai Z, Chen Y, Esplugues E, Wen R, Wang D, Parish IA, Zajac AJ, Craft J, Cui W) Cell Rep 2015 Nov 10;13(6):1118-1124 92 Citations |
| 1 | The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice. (Presa M, Chen YG, Grier AE, Leiter EH, Brehm MA, Greiner DL, Shultz LD, Serreze DV) J Immunol 2015 Oct 01;195(7):3011-9 11 Citations |
| 2 | TCR signaling intensity controls CD8+ T cell responsiveness to TGF-β. (Arumugam V, Bluemn T, Wesley E, Schmidt AM, Kambayashi T, Malarkannan S, Riese MJ) J Leukoc Biol 2015 Nov;98(5):703-12 22 Citations |
| 1 | MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice. (Wu Y, Heinrichs J, Bastian D, Fu J, Nguyen H, Schutt S, Liu Y, Jin J, Liu C, Li QJ, Xia C, Yu XZ) Blood 2015 Sep 10;126(11):1314-23 52 Citations |
| 1 | Structural Determinants for the Selective Anti-HIV-1 Activity of the All-β Alternative Conformer of XCL1. (Guzzo C, Fox JC, Miao H, Volkman BF, Lusso P) J Virol 2015 Sep;89(17):9061-7 11 Citations |
| 1 | Editorial: Crossing the divide: a novel Cd8 enhancer with activity in CTLs and CD8αα+ dendritic cells. (Jeschke JC, Williams CB) J Leukoc Biol 2015 Apr;97(4):623-5 1 Citation |
| 1 | Elite control of HIV: is this the right model for a functional cure? (Cockerham LR, Hatano H) Trends Microbiol 2015 Feb;23(2):71-5 23 Citations |
| 1 | Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes. (Papadakis KA, Krempski J, Reiter J, Svingen P, Xiong Y, Sarmento OF, Huseby A, Johnson AJ, Lomberk GA, Urrutia RA, Faubion WA) Am J Physiol Cell Physiol 2015 Mar 01;308(5):C362-71 23 Citations |
| 1 | CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. (Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG) PLoS One 2014;9(10):e110731 82 Citations |
| 1 | NF-κB is crucial in proximal T-cell signaling for calcium influx and NFAT activation. (Bronk CC, Yoder S, Hopewell EL, Yang S, Celis E, Yu XZ, Beg AA) Eur J Immunol 2014 Dec;44(12):3741-6 9 Citations |
| 1 | Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. (Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ) PLoS One 2014;9(8):e102709 26 Citations |
| 1 | Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy. (Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK) J Infect Dis 2014 Dec 01;210(11):1838-43 10 Citations |
| 1 | Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease. (Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG) AIDS 2014 Jul 31;28(12):1749-58 89 Citations |
| 2 | Mice with an absent stress response are protected against ischemic renal injury. (Sreedharan R, Chen S, Miller M, Haribhai D, Williams CB, Van Why SK) Kidney Int 2014 Sep;86(3):515-24 10 Citations |
| 1 | High-dose IgG therapy mitigates bile duct-targeted inflammation and obstruction in a mouse model of biliary atresia. (Fenner EK, Boguniewicz J, Tucker RM, Sokol RJ, Mack CL) Pediatr Res 2014 Jul;76(1):72-80 17 Citations |
| 1 | Human pegivirus RNA is found in multiple blood mononuclear cells in vivo and serum-derived viral RNA-containing particles are infectious in vitro. (Chivero ET, Bhattarai N, Rydze RT, Winters MA, Holodniy M, Stapleton JT) J Gen Virol 2014 Jun;95(Pt 6):1307-1319 62 Citations |
| 1 | The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1. (Guzzo C, Fox J, Lin Y, Miao H, Cimbro R, Volkman BF, Fauci AS, Lusso P) PLoS Pathog 2013;9(12):e1003852 31 Citations |
| 2 | Regulation of antiviral CD8 T-cell responses. (Kulinski JM, Tarakanova VL, Verbsky J) Crit Rev Immunol 2013;33(6):477-88 20 Citations |
| 1 | Localized interleukin-12 delivery for immunotherapy of solid tumours. (Wei LZ, Xu Y, Nelles EM, Furlonger C, Wang JC, Di Grappa MA, Khokha R, Medin JA, Paige CJ) J Cell Mol Med 2013 Nov;17(11):1465-74 14 Citations |
| 1 | Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function. (Sckisel GD, Tietze JK, Zamora AE, Hsiao HH, Priest SO, Wilkins DE, Lanier LL, Blazar BR, Baumgarth N, Murphy WJ) Clin Exp Immunol 2014 Jan;175(1):79-91 43 Citations |
| 1 | Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes. (Dubovsky JA, Beckwith KA, Natarajan G, Woyach JA, Jaglowski S, Zhong Y, Hessler JD, Liu TM, Chang BY, Larkin KM, Stefanovski MR, Chappell DL, Frissora FW, Smith LL, Smucker KA, Flynn JM, Jones JA, Andritsos LA, Maddocks K, Lehman AM, Furman R, Sharman J, Mishra A, Caligiuri MA, Satoskar AR, Buggy JJ, Muthusamy N, Johnson AJ, Byrd JC) Blood 2013 Oct 10;122(15):2539-49 628 Citations |
| 1 | Premature cell senescence and T cell receptor-independent activation of CD8+ T cells in juvenile idiopathic arthritis. (Dvergsten JA, Mueller RG, Griffin P, Abedin S, Pishko A, Michel JJ, Rosenkranz ME, Reed AM, Kietz DA, Vallejo AN) Arthritis Rheum 2013 Aug;65(8):2201-10 29 Citations |
| 2 | Programmed death receptor-1/programmed death receptor ligand-1 blockade after transient lymphodepletion to treat myeloma. (Kearl TJ, Jing W, Gershan JA, Johnson BD) J Immunol 2013 Jun 01;190(11):5620-8 83 Citations |
| 1 | DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity. (Chuang I, Sedegah M, Cicatelli S, Spring M, Polhemus M, Tamminga C, Patterson N, Guerrero M, Bennett JW, McGrath S, Ganeshan H, Belmonte M, Farooq F, Abot E, Banania JG, Huang J, Newcomer R, Rein L, Litilit D, Richie NO, Wood C, Murphy J, Sauerwein R, Hermsen CC, McCoy AJ, Kamau E, Cummings J, Komisar J, Sutamihardja A, Shi M, Epstein JE, Maiolatesi S, Tosh D, Limbach K, Angov E, Bergmann-Leitner E, Bruder JT, Doolan DL, King CR, Carucci D, Dutta S, Soisson L, Diggs C, Hollingdale MR, Ockenhouse CF, Richie TL) PLoS One 2013;8(2):e55571 116 Citations |
| 1 | Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms. (Yu Y, Cho HI, Wang D, Kaosaard K, Anasetti C, Celis E, Yu XZ) J Immunol 2013 Feb 15;190(4):1873-81 52 Citations |
| 1 | Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis. (Kron MA, Metwali A, Vodanovic-Jankovic S, Elliott D) Clin Vaccine Immunol 2013 Feb;20(2):276-81 35 Citations |
| 1 | GB virus C infection is associated with a reduced rate of reactivation of latent HIV and protection against activation-induced T-cell death. (Rydze RT, Bhattarai N, Stapleton JT) Antivir Ther 2012;17(7):1271-9 31 Citations |
| 1 | GB virus C viremia is associated with higher levels of double-negative T cells and lower T-cell activation in HIV-infected individuals receiving antiretroviral therapy. (Bhattarai N, Rydze RT, Chivero ET, Stapleton JT) J Infect Dis 2012 Nov;206(9):1469-72 19 Citations |
| 1 | Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. (Ip CW, Kroner A, Groh J, Huber M, Klein D, Spahn I, Diem R, Williams SK, Nave KA, Edgar JM, Martini R) PLoS One 2012;7(8):e42554 27 Citations |
| 1 | Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse. (Bobbala D, Chen XL, Leblanc C, Mayhue M, Stankova J, Tanaka T, Chen YG, Ilangumaran S, Ramanathan S) Diabetologia 2012 Nov;55(11):3010-20 33 Citations |
| 1 | Transient CD8-memory contraction: a potential contributor to latent cytomegalovirus reactivation. (Campbell J, Trgovcich J, Kincaid M, Zimmerman PD, Klenerman P, Sims S, Cook CH) J Leukoc Biol 2012 Nov;92(5):933-7 12 Citations |
| 1 | BRAF(V600) inhibitor GSK2118436 targeted inhibition of mutant BRAF in cancer patients does not impair overall immune competency. (Hong DS, Vence L, Falchook G, Radvanyi LG, Liu C, Goodman V, Legos JJ, Blackman S, Scarmadio A, Kurzrock R, Lizee G, Hwu P) Clin Cancer Res 2012 Apr 15;18(8):2326-35 95 Citations |
| 1 | Granzyme B regulates antiviral CD8+ T cell responses. (Salti SM, Hammelev EM, Grewal JL, Reddy ST, Zemple SJ, Grossman WJ, Grayson MH, Verbsky JW) J Immunol 2011 Dec 15;187(12):6301-9 59 Citations |
| 1 | BB rat Gimap gene expression in sorted lymphoid T and B cells. (Moralejo DH, Fuller JM, Rutledge EA, Van Yserloo B, Ettinger RA, Jensen R, Osborne W, Kwitek A, Lernmark A) Life Sci 2011 Nov 07;89(19-20):748-54 9 Citations |
| 1 | Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation. (Kwun J, Malarkannan S, Burlingham WJ, Knechtle SJ) J Immunol 2011 Oct 15;187(8):3997-4006 15 Citations |
| 1 | CD103 deficiency prevents graft-versus-host disease but spares graft-versus-tumor effects mediated by alloreactive CD8 T cells. (Liu K, Anthony BA, Yearsly MM, Hamadani M, Gaughan A, Wang JJ, Devine SM, Hadley GA) PLoS One 2011;6(7):e21968 10 Citations |
| 1 | Dual antigen target-based immunotherapy for prostate cancer eliminates the growth of established tumors in mice. (Karan D, Dubey S, Van Veldhuizen P, Holzbeierlein JM, Tawfik O, Thrasher JB) Immunotherapy 2011 Jun;3(6):735-46 20 Citations |
| 2 | Immunosuppressive effects of multiple myeloma are overcome by PD-L1 blockade. (Hallett WH, Jing W, Drobyski WR, Johnson BD) Biol Blood Marrow Transplant 2011 Aug;17(8):1133-45 137 Citations |
| 1 | Depletion of CD25⁺ T cells from hematopoietic stem cell grafts increases posttransplantation vaccine-induced immunity to neuroblastoma. (Jing W, Yan X, Hallett WH, Gershan JA, Johnson BD) Blood 2011 Jun 23;117(25):6952-62 37 Citations |
| 1 | Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model. (Felizardo TC, Wang JC, McGray RA, Evelegh C, Spaner DE, Fowler DH, Bramson JL, Medin JA) Gene Ther 2011 Oct;18(10):986-95 11 Citations |
| 1 | Unmasking genes in a type 1 diabetes-resistant mouse strain that enhances pathogenic CD8 T-cell responses. (Driver JP, Chen YG, Zhang W, Asrat S, Serreze DV) Diabetes 2011 Apr;60(4):1354-9 4 Citations |
| 1 | Functional dichotomy between NKG2D and CD28-mediated co-stimulation in human CD8+ T cells. (Rajasekaran K, Xiong V, Fong L, Gorski J, Malarkannan S) PLoS One 2010 Sep 09;5(9) 35 Citations |
| 2 | Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice. (Kerschen E, Hernandez I, Zogg M, Jia S, Hessner MJ, Fernandez JA, Griffin JH, Huettner CS, Castellino FJ, Weiler H) J Clin Invest 2010 Sep;120(9):3167-78 82 Citations |
| 1 | Early expression of stem cell-associated genes within the CD8 compartment after treatment with a tumor vaccine. (Kohler ME, Hallett WH, Chen QR, Khan J, Johnson BD, Orentas RJ) Cell Immunol 2010;265(1):65-73 4 Citations |
| 1 | Graft-versus-host disease: role of inflammation in the development of chromosomal abnormalities of keratinocytes. (Sloand EM, Pfannes L, Ling C, Feng X, Jasek M, Calado R, Tucker ZC, Hematti P, Maciejewski J, Dunbar C, Barrett J, Young N) Biol Blood Marrow Transplant 2010 Dec;16(12):1665-73 19 Citations |
| 1 | CD8-positive primary cutaneous anaplastic large T-cell lymphoma (PCALCL): case report and review of this unusual variant of PCALCL. (Plaza JA, Ortega P, Lynott J, Mullane M, Kroft S, Olteanu H) Am J Dermatopathol 2010 Jul;32(5):489-91 16 Citations |
| 1 | MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques. (O'Connor SL, Lhost JJ, Becker EA, Detmer AM, Johnson RC, Macnair CE, Wiseman RW, Karl JA, Greene JM, Burwitz BJ, Bimber BN, Lank SM, Tuscher JJ, Mee ET, Rose NJ, Desrosiers RC, Hughes AL, Friedrich TC, Carrington M, O'Connor DH) Sci Transl Med 2010 Mar 10;2(22):22ra18 76 Citations |
| 1 | Generation of cytotoxic T-cell lines using overlapping pentadecapeptides derived from conserved regions of the adenovirus hexon protein. (Zhu F, Xu H, Tsao A, Margolis DA, Keever-Taylor CA) J Gen Virol 2010 Jun;91(Pt 6):1577-89 5 Citations |
| 1 | Acid sphingomyelinase deficiency does not protect from graft-versus-host disease in transplant recipients with Niemann-Pick disease. (Tolar J, Eapen M, Orchard PJ, Blazar BR) Blood 2010 Jan 14;115(2):434-5 3 Citations |
| 1 | Ectopic T-cell specificity and absence of perforin and granzyme B alleviate neural damage in oligodendrocyte mutant mice. (Kroner A, Ip CW, Thalhammer J, Nave KA, Martini R) Am J Pathol 2010 Feb;176(2):549-55 22 Citations |
| 1 | Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques. (Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M Jr, O'Connor D, Lifson JD, Roederer M, Ohlen C) J Immunol 2010 Jan 01;184(1):303-14 33 Citations |
| 1 | Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette. (Driver JP, Scheuplein F, Chen YG, Grier AE, Wilson SB, Serreze DV) Diabetes 2010 Feb;59(2):423-32 24 Citations |
| 1 | PD-1 regulates neural damage in oligodendroglia-induced inflammation. (Kroner A, Schwab N, Ip CW, Leder C, Nave KA, Mäurer M, Wiendl H, Martini R) PLoS One 2009;4(2):e4405 18 Citations |
| 1 | Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory. (Jing W, Gershan JA, Johnson BD) Blood 2009 Apr 30;113(18):4449-57 39 Citations |
| 1 | Tacrolimus (FK506) causes disease aggravation in models for inherited peripheral myelinopathies. (Ip CW, Kroner A, Kohl B, Wessig C, Martini R) Neurobiol Dis 2009 Feb;33(2):207-12 7 Citations |
| 1 | The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy. (Kroner A, Schwab N, Ip CW, Sommer C, Wessig C, Wiendl H, Martini R) Neurobiol Dis 2009 Jan;33(1):96-103 12 Citations |
| 1 | Overexpression of CD7 in classical Hodgkin lymphoma-infiltrating T lymphocytes. (Seegmiller AC, Karandikar NJ, Kroft SH, McKenna RW, Xu Y) Cytometry B Clin Cytom 2009 May;76(3):169-74 27 Citations |
| 1 | Induction of a VLA-2 (CD49b)-expressing effector T cell population by a cell-based neuroblastoma vaccine expressing CD137L. (Yan X, Johnson BD, Orentas RJ) J Immunol 2008 Oct 01;181(7):4621-31 15 Citations |
| 5 | Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. (Schulteis RD, Chu H, Dai X, Chen Y, Edwards B, Haribhai D, Williams CB, Malarkannan S, Hessner MJ, Glisic-Milosavljevic S, Jana S, Kerschen EJ, Ghosh S, Wang D, Kwitek AE, Lernmark A, Gorski J, Weiler H) Blood 2008 Dec 15;112(13):4905-14 54 Citations |
| 2 | Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice. (Chen YG, Scheuplein F, Osborne MA, Tsaih SW, Chapman HD, Serreze DV) Diabetes 2008 Dec;57(12):3273-80 18 Citations |
| 1 | Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice. (Mukhopadhaya A, Hanafusa T, Jarchum I, Chen YG, Iwai Y, Serreze DV, Steinman RM, Tarbell KV, DiLorenzo TP) Proc Natl Acad Sci U S A 2008 Apr 29;105(17):6374-9 122 Citations |
| 1 | Tumor protection following vaccination with low doses of lentivirally transduced DCs expressing the self-antigen erbB2. (Mossoba ME, Walia JS, Rasaiah VI, Buxhoeveden N, Head R, Ying C, Foley JE, Bramson JL, Fowler DH, Medin JA) Mol Ther 2008 Mar;16(3):607-17 22 Citations |
| 1 | Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice. (Leder C, Schwab N, Ip CW, Kroner A, Nave KA, Dornmair K, Martini R, Wiendl H) Mol Cell Neurosci 2007 Nov;36(3):416-24 17 Citations |
| 1 | A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia. (Roman LD, Wilczynski S, Muderspach LI, Burnett AF, O'Meara A, Brinkman JA, Kast WM, Facio G, Felix JC, Aldana M, Weber JS) Gynecol Oncol 2007 Sep;106(3):558-66 96 Citations |
| 1 | Oligoclonal expansions of CD4+ and CD8+ T-cells in the target organ of patients with biliary atresia. (Mack CL, Falta MT, Sullivan AK, Karrer F, Sokol RJ, Freed BM, Fontenot AP) Gastroenterology 2007 Jul;133(1):278-87 94 Citations |
| 1 | Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine. (Karan D, Krieg AM, Lubaroff DM) Int J Cancer 2007 Oct 01;121(7):1520-8 41 Citations |
| 1 | Monkeypox without exanthem. (Lewis MW, Graham MB, Hammarlund E, Hanifin J, Slifka MK) N Engl J Med 2007 May 17;356(20):2112-4 24 Citations |
| 1 | Epicutaneous (EC) immunization with myelin basic protein (MBP) induces TCRalphabeta+ CD4+ CD8+ double positive suppressor cells that protect from experimental autoimmune encephalomyelitis (EAE). (Tutaj M, Szczepanik M) J Autoimmun 2007 Jun;28(4):208-15 43 Citations |
| 1 | Induction of natural killer cell responses by ectromelia virus controls infection. (Parker AK, Parker S, Yokoyama WM, Corbett JA, Buller RM) J Virol 2007 Apr;81(8):4070-9 92 Citations |
| 1 | Gammadelta T cells do not require fully functional cytotoxic pathways or the ability to recognize recipient alloantigens to prevent graft rejection. (Vodanovic-Jankovic S, Drobyski WR) Biol Blood Marrow Transplant 2006 Nov;12(11):1125-34 6 Citations |
| 1 | Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice. (Ip CW, Kroner A, Crocker PR, Nave KA, Martini R) Neurobiol Dis 2007 Jan;25(1):105-11 49 Citations |
| 1 | Role of immune cells in animal models for inherited peripheral neuropathies. (Wang Ip C, Kroner A, Fischer S, Berghoff M, Kobsar I, Mäurer M, Martini R) Neuromolecular Med 2006;8(1-2):175-90 40 Citations |
| 1 | Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells. (Yu XZ, Liang Y, Nurieva RI, Guo F, Anasetti C, Dong C) J Immunol 2006 Jun 15;176(12):7394-401 43 Citations |
| 1 | Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion. (Chen J, Chen YG, Reifsnyder PC, Schott WH, Lee CH, Osborne M, Scheuplein F, Haag F, Koch-Nolte F, Serreze DV, Leiter EH) J Immunol 2006 Apr 15;176(8):4590-9 52 Citations |
| 1 | Alloantigen affinity and CD4 help determine severity of graft-versus-host disease mediated by CD8 donor T cells. (Yu XZ, Albert MH, Anasetti C) J Immunol 2006 Mar 15;176(6):3383-90 23 Citations |
| 1 | Attenuated demyelination in the absence of the macrophage-restricted adhesion molecule sialoadhesin (Siglec-1) in mice heterozygously deficient in P0. (Kobsar I, Oetke C, Kroner A, Wessig C, Crocker P, Martini R) Mol Cell Neurosci 2006 Apr;31(4):685-91 37 Citations |
| 1 | Memory stem cells sustain disease. (Yu XZ, Anasetti C) Nat Med 2005 Dec;11(12):1282-3 4 Citations |
| 1 | Epicutaneously induced TGF-beta-dependent tolerance inhibits experimental autoimmune encephalomyelitis. (Szczepanik M, Tutaj M, Bryniarski K, Dittel BN) J Neuroimmunol 2005 Jul;164(1-2):105-14 47 Citations |
| 1 | Epicutaneous immunization induces alphabeta T-cell receptor CD4 CD8 double-positive non-specific suppressor T cells that inhibit contact sensitivity via transforming growth factor-beta. (Szczepanik M, Bryniarski K, Tutaj M, Ptak M, Skrzeczynska J, Askenase PW, Ptak W) Immunology 2005 May;115(1):42-54 56 Citations |
| 1 | Efficient transfer of PSA and PSMA cDNAs into DCs generates antibody and T cell antitumor responses in vivo. (Medin JA, Liang SB, Hou JW, Kelley LS, Peace DJ, Fowler DH) Cancer Gene Ther 2005 Jun;12(6):540-51 24 Citations |
| 1 | Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes. (Chen YG, Choisy-Rossi CM, Holl TM, Chapman HD, Besra GS, Porcelli SA, Shaffer DJ, Roopenian D, Wilson SB, Serreze DV) J Immunol 2005 Feb 01;174(3):1196-204 123 Citations |
| 1 | Tracking ex vivo-expanded CD4+CD25+ and CD8+CD25+ regulatory T cells after infusion to prevent donor lymphocyte infusion-induced lethal acute graft-versus-host disease. (Xia G, Kovochich M, Truitt RL, Johnson BD) Biol Blood Marrow Transplant 2004 Nov;10(11):748-60 26 Citations |
| 1 | Phosphatidylserine regulates the maturation of human dendritic cells. (Chen X, Doffek K, Sugg SL, Shilyansky J) J Immunol 2004 Sep 01;173(5):2985-94 92 Citations |
| 1 | Unusual immunophenotype of CD8+ T cells in familial hemophagocytic lymphohistiocytosis. (Karandikar NJ, Kroft SH, Yegappan S, Rogers BB, Aquino VM, Lee KM, Kumar V, Guenaga FJ, Jaffe ES, Douek DC, McKenna RW) Blood 2004 Oct 01;104(7):2007-9 22 Citations |
| 1 | CD28 ligation induces transplantation tolerance by IFN-gamma-dependent depletion of T cells that recognize alloantigens. (Yu XZ, Albert MH, Martin PJ, Anasetti C) J Clin Invest 2004 Jun;113(11):1624-30 56 Citations |
| 1 | Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation. (Mack CL, Tucker RM, Sokol RJ, Karrer FM, Kotzin BL, Whitington PF, Miller SD) Pediatr Res 2004 Jul;56(1):79-87 179 Citations |
| 1 | Murine CD8 lymphocyte expansion in vitro by artificial antigen-presenting cells expressing CD137L (4-1BBL) is superior to CD28, and CD137L expressed on neuroblastoma expands CD8 tumour-reactive effector cells in vivo. (Yan X, Johnson BD, Orentas RJ) Immunology 2004 May;112(1):105-16 30 Citations |
| 1 | Elimination of leukemia in the absence of lethal graft-versus-host disease after allogenic bone marrow transplantation. (Drobyski WR, Gendelman M, Vodanovic-Jankovic S, Gorski J) J Immunol 2003 Mar 15;170(6):3046-53 16 Citations |
| 1 | CD28 signal enhances apoptosis of CD8 T cells after strong TCR ligation. (Yu XZ, Martin PJ, Anasetti C) J Immunol 2003 Mar 15;170(6):3002-6 28 Citations |
| 1 | Real-time T-cell profiling identifies H60 as a major minor histocompatibility antigen in murine graft-versus-host disease. (Choi EY, Christianson GJ, Yoshimura Y, Jung N, Sproule TJ, Malarkannan S, Joyce S, Roopenian DC) Blood 2002 Dec 15;100(13):4259-65 62 Citations |
| 1 | Cellular sources and targets of IFN-gamma-mediated protection against viral demyelination and neurological deficits. (Murray PD, McGavern DB, Pease LR, Rodriguez M) Eur J Immunol 2002 Mar;32(3):606-15 30 Citations |
| 1 | Chemokine expression in the central nervous system of mice with a viral disease resembling multiple sclerosis: roles of CD4+ and CD8+ T cells and viral persistence. (Ransohoff RM, Wei T, Pavelko KD, Lee JC, Murray PD, Rodriguez M) J Virol 2002 Mar;76(5):2217-24 43 Citations |
| 1 | Spontaneous remyelination following extensive demyelination is associated with improved neurological function in a viral model of multiple sclerosis. (Murray PD, McGavern DB, Sathornsumetee S, Rodriguez M) Brain 2001 Jul;124(Pt 7):1403-16 60 Citations |
| 1 | Quantitative analysis of the immune response to mouse non-MHC transplantation antigens in vivo: the H60 histocompatibility antigen dominates over all others. (Choi EY, Yoshimura Y, Christianson GJ, Sproule TJ, Malarkannan S, Shastri N, Joyce S, Roopenian DC) J Immunol 2001 Apr 01;166(7):4370-9 69 Citations |
| 1 | Impaired expression of the CD3-zeta chain in peripheral blood T cells of patients with chronic myeloid leukaemia results in an increased susceptibility to apoptosis. (Chen X, Woiciechowsky A, Raffegerst S, Schendel D, Kolb HJ, Roskrow M) Br J Haematol 2000 Dec;111(3):817-25 54 Citations |
| 1 | Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells. (Carpenter PA, Pavlovic S, Tso JY, Press OW, Gooley T, Yu XZ, Anasetti C) J Immunol 2000 Dec 01;165(11):6205-13 89 Citations |
| 1 | Generation of antigen-specific, lacZ-inducible T-cell hybrids. (Malarkannan S, Mendoza LM, Shastri N) Methods Mol Biol 2001;156:265-72 18 Citations |
| 1 | Identification of CD8+ T-cell-stimulating antigen genes in cDNA libraries. (Mendoza LM, Malarkannan S, Shastri N) Methods Mol Biol 2001;156:255-63 3 Citations |
| 1 | Ligand-specific selection of MHC class II-restricted thymocytes in fetal thymic organ culture. (Kersh GJ, Engle DL, Williams CB, Allen PM) J Immunol 2000 Jun 01;164(11):5675-82 10 Citations |
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| 1 | Graft-facilitating doses of ex vivo activated gammadelta T cells do not cause lethal murine graft-vs.-host disease. (Drobyski WR, Majewski D, Hanson G) Biol Blood Marrow Transplant 1999;5(4):222-30 61 Citations |
| 1 | Graft-vs.-host and graft-vs.-leukemia reactions after delayed infusions of donor T-subsets. (Johnson BD, Becker EE, Truitt RL) Biol Blood Marrow Transplant 1999;5(3):123-32 54 Citations |
| 1 | Ex vivo anti-CD3 antibody-activated donor T cells have a reduced ability to cause lethal murine graft-versus-host disease but retain their ability to facilitate alloengraftment. (Drobyski WR, Majewski D, Ozker K, Hanson G) J Immunol 1998 Sep 01;161(5):2610-9 46 Citations |
| 1 | CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis. (Murray PD, Pavelko KD, Leibowitz J, Lin X, Rodriguez M) J Virol 1998 Sep;72(9):7320-9 110 Citations |
| 1 | Theiler's virus infection of genetically susceptible mice induces central nervous system-infiltrating CTLs with no apparent viral or major myelin antigenic specificity. (Lin X, Pease LR, Murray PD, Rodriguez M) J Immunol 1998 Jun 01;160(11):5661-8 32 Citations |
| 1 | Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice. (Graham MB, Braciale TJ) J Exp Med 1997 Dec 15;186(12):2063-8 201 Citations |
| 1 | IL-2 induces Fas ligand/Fas (CD95L/CD95) cytotoxicity in CD8+ and CD4+ T lymphocyte clones. (Esser MT, Dinglasan RD, Krishnamurthy B, Gullo CA, Graham MB, Braciale VL) J Immunol 1997 Jun 15;158(12):5612-8 52 Citations |
| 1 | The role of CD4+ and CD8+ T cells in demyelinating disease following Theiler's virus infection: a model for multiple sclerosis. (Rodriguez M, Rivera-Quinones C, Murray PD, Kariuki Njenga M, Wettstein PJ, Mak T) J Neurovirol 1997 May;3 Suppl 1:S43-5 10 Citations |
| 1 | Response duration and recovery of CD4+ lymphocytes following deoxycoformycin in interferon-alpha-resistant hairy cell leukemia: 7-year follow-up. (Seymour JF, Talpaz M, Kurzrock R) Leukemia 1997 Jan;11(1):42-7 64 Citations |
| 1 | The mouse mammary tumor virus env gene is the source of a CD8+ T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma. (Malarkannan S, Serwold T, Nguyen V, Sherman LA, Shastri N) Proc Natl Acad Sci U S A 1996 Nov 26;93(24):13991-6 23 Citations |
| 1 | Alloreactive CD8+ T cells can recognize unusual, rare, and unique processed peptide/MHC complexes. (Malarkannan S, Gonzalez F, Nguyen V, Adair G, Shastri N) J Immunol 1996 Nov 15;157(10):4464-73 36 Citations |
| 1 | Psychological disturbance differentially alters CD4+ and CD8+ leukocytes in the blood and intrathecal compartments. (Hou FY, Coe CL, Erickson C) J Neuroimmunol 1996 Aug;68(1-2):13-8 10 Citations |
| 1 | A monoclonal natural autoantibody that promotes remyelination suppresses central nervous system inflammation and increases virus expression after Theiler's virus-induced demyelination. (Miller DJ, Njenga MK, Murray PD, Leibowitz J, Rodriguez M) Int Immunol 1996 Jan;8(1):131-41 29 Citations |
| 1 | Human immunodeficiency virus (HIV) type 1 infection status and in vitro susceptibility to HIV infection among high-risk HIV-1-seronegative hemophiliacs. (Lederman MM, Jackson JB, Kroner BL, White GC 3rd, Eyster ME, Aledort LM, Hilgartner MW, Kessler CM, Cohen AR, Kiger KP) J Infect Dis 1995 Jul;172(1):228-31 13 Citations |
