Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Publications indexed to the term Loss of Heterozygosity

FacultyTitle
1Determinants of mosaic chromosomal alteration fitness. (Pershad Y, Mack T, Poisner H, Jakubek YA, Stilp AM, Mitchell BD, Lewis JP, Boerwinkle E, Loos RJF, Chami N, Wang Z, Barnes K, Pankratz N, Fornage M, Redline S, Psaty BM, Bis JC, Shojaie A, Silverman EK, Cho MH, Yun JH, DeMeo D, Levy D, Johnson AD, Mathias RA, Taub MA, Arnett D, North KE, Raffield LM, Carson AP, Doyle MF, Rich SS, Rotter JI, Guo X, Cox NJ, Roden DM, Franceschini N, Desai P, Reiner AP, Auer PL, Scheet PA, Jaiswal S, Weinstock JS, Bick AG) Nat Commun 2024 May 07;15(1):3800       8 Citations
1Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. (Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf D, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I, Cancer Genome Atlas Research Network, Monnat RJ Jr, Xiao Y, Wang C) Cell Rep 2018 Apr 03;23(1):239-254.e6       910 Citations
1Single-molecule analysis reveals widespread structural variation in multiple myeloma. (Gupta A, Place M, Goldstein S, Sarkar D, Zhou S, Potamousis K, Kim J, Flanagan C, Li Y, Newton MA, Callander NS, Hematti P, Bresnick EH, Ma J, Asimakopoulos F, Schwartz DC) Proc Natl Acad Sci U S A 2015 Jun 23;112(25):7689-94       49 Citations
1Fhit deficiency-induced global genome instability promotes mutation and clonal expansion. (Miuma S, Saldivar JC, Karras JR, Waters CE, Paisie CA, Wang Y, Jin V, Sun J, Druck T, Zhang J, Huebner K) PLoS One 2013;8(11):e80730       29 Citations
1Single nucleotide polymorphism array analysis of bone marrow failure patients reveals characteristic patterns of genetic changes. (Babushok DV, Xie HM, Roth JJ, Perdigones N, Olson TS, Cockroft JD, Gai X, Perin JC, Li Y, Paessler ME, Hakonarson H, Podsakoff GM, Mason PJ, Biegel JA, Bessler M) Br J Haematol 2014 Jan;164(1):73-82       22 Citations
1Enhancing diagnosis, prognosis, and therapeutic outcome prediction of gliomas using genomics. (Assem M, Sibenaller Z, Agarwal S, Al-Keilani MS, Alqudah MA, Ryken TC) OMICS 2012 Mar;16(3):113-22       26 Citations
1Methylation not a frequent "second hit" in tumors with germline BRCA mutations. (Dworkin AM, Spearman AD, Tseng SY, Sweet K, Toland AE) Fam Cancer 2009;8(4):339-46       57 Citations
1Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors. (Jackson EM, Sievert AJ, Gai X, Hakonarson H, Judkins AR, Tooke L, Perin JC, Xie H, Shaikh TH, Biegel JA) Clin Cancer Res 2009 Mar 15;15(6):1923-30       177 Citations
1Clinically applicable models to characterize BRCA1 and BRCA2 variants of uncertain significance. (Spearman AD, Sweet K, Zhou XP, McLennan J, Couch FJ, Toland AE) J Clin Oncol 2008 Nov 20;26(33):5393-400       73 Citations
1Infertility and abnormal cervical mucus in two sisters who are compound heterozygotes for the cystic fibrosis (CF) DeltaF508 and R117H/7T mutations. (Schoyer KD, Gilbert F, Rosenwaks Z) Fertil Steril 2008 Oct;90(4):1201.e19-22       17 Citations
2Direct evidence for epithelial-mesenchymal transitions in breast cancer. (Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G) Cancer Res 2008 Feb 01;68(3):937-45       328 Citations
1CD83 gene polymorphisms increase susceptibility to human invasive cervical cancer. (Zhang Z, Borecki I, Nguyen L, Ma D, Smith K, Huettner PC, Mutch DG, Herzog TJ, Gibb RK, Powell MA, Grigsby PW, Massad LS, Hernandez E, Judson PL, Swisher EM, Crowder S, Li J, Gerhard DS, Rader JS) Cancer Res 2007 Dec 01;67(23):11202-8       32 Citations
1MLH3 mutation in endometrial cancer. (Taylor NP, Powell MA, Gibb RK, Rader JS, Huettner PC, Thibodeau SN, Mutch DG, Goodfellow PJ) Cancer Res 2006 Aug 01;66(15):7502-8       27 Citations
1DNA mismatch repair and TP53 defects are early events in uterine carcinosarcoma tumorigenesis. (Taylor NP, Zighelboim I, Huettner PC, Powell MA, Gibb RK, Rader JS, Mutch DG, Edmonston TB, Goodfellow PJ) Mod Pathol 2006 Oct;19(10):1333-8       66 Citations
1Fine mapping and evaluation of candidate genes for cervical cancer on 11q23. (Zhang Z, Gerhard DS, Nguyen L, Li J, Traugott A, Huettner PC, Rader JS) Genes Chromosomes Cancer 2005 May;43(1):95-103       15 Citations
1Characterization of FRA6E and its potential role in autosomal recessive juvenile parkinsonism and ovarian cancer. (Denison SR, Callahan G, Becker NA, Phillips LA, Smith DI) Genes Chromosomes Cancer 2003 Sep;38(1):40-52       127 Citations
1Characterization of the common fragile site FRA9E and its potential role in ovarian cancer. (Callahan G, Denison SR, Phillips LA, Shridhar V, Smith DI) Oncogene 2003 Jan 30;22(4):590-601       64 Citations
1Oligodendroglioma: pathology and molecular biology. (Engelhard HH, Stelea A, Cochran EJ) Surg Neurol 2002 Aug;58(2):111-7; discussion 117       83 Citations
1Loss of heterozygosity at 11q23.3 in vasculoinvasive and metastatic squamous cell carcinoma of the cervix. (O'sullivan MJ, Rader JS, Gerhard DS, Li Y, Trinkaus KM, Gersell DJ, Huettner PC) Hum Pathol 2001 May;32(5):475-8       17 Citations
1Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. (Agathanggelou A, Honorio S, Macartney DP, Martinez A, Dallol A, Rader J, Fullwood P, Chauhan A, Walker R, Shaw JA, Hosoe S, Lerman MI, Minna JD, Maher ER, Latif F) Oncogene 2001 Mar 22;20(12):1509-18       376 Citations
1Population risk and physiological rate parameters for colon cancer. The union of an explicit model for carcinogenesis with the public health records of the United States. (Herrero-Jimenez P, Tomita-Mitchell A, Furth EE, Morgenthaler S, Thilly WG) Mutat Res 2000 Jan 17;447(1):73-116       44 Citations
1Detailed genetic and physical mapping of tumor suppressor loci on chromosome 3p in ovarian cancer. (Fullwood P, Marchini S, Rader JS, Martinez A, Macartney D, Broggini M, Morelli C, Barbanti-Brodano G, Maher ER, Latif F) Cancer Res 1999 Sep 15;59(18):4662-7       55 Citations
1Genetic analysis of prostatic atypical adenomatous hyperplasia (adenosis). (Doll JA, Zhu X, Furman J, Kaleem Z, Torres C, Humphrey PA, Donis-Keller H) Am J Pathol 1999 Sep;155(3):967-71       39 Citations
1Frequent deletions within FRA7G at 7q31.2 in invasive epithelial ovarian cancer. (Huang H, Reed CP, Mordi A, Lomberk G, Wang L, Shridhar V, Hartmann L, Jenkins R, Smith DI) Genes Chromosomes Cancer 1999 Jan;24(1):48-55       40 Citations
1Mapping an endometrial cancer tumor suppressor gene at 10q25 and development of a bacterial clone contig for the consensus deletion interval. (Peiffer-Schneider S, Noonan FC, Mutch DG, Simpkins SB, Herzog T, Rader J, Elbendary A, Gersell DJ, Call K, Goodfellow PJ) Genomics 1998 Aug 15;52(1):9-16       31 Citations
1Analysis of MSH3 in endometrial cancers with defective DNA mismatch repair. (Swisher EM, Mutch DG, Herzog TJ, Rader JS, Kowalski LD, Elbendary A, Goodfellow PJ) J Soc Gynecol Investig 1998;5(4):210-6       19 Citations
1Cervical intraepithelial neoplasia III shows frequent allelic loss in 3p and 6p. (Rader JS, Gerhard DS, O'Sullivan MJ, Li Y, Li L, Liapis H, Huettner PC) Genes Chromosomes Cancer 1998 May;22(1):57-65       49 Citations