3 | Interleukin-9 production by type 2 innate lymphoid cells induces Paneth cell metaplasia and small intestinal remodeling. (Yuan C, Rayasam A, Moe A, Hayward M, Wells C, Szabo A, Mackenzie A, Salzman N, Drobyski WR) Nat Commun 2023 Dec 02;14(1):7963 1 Citation |
1 | The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut. (Ramadan R, Wouters VM, van Neerven SM, de Groot NE, Garcia TM, Muncan V, Franklin OD, Battle M, Carlson KS, Leach J, Sansom OJ, Boulard O, Chamaillard M, Vermeulen L, Medema JP, Huels DJ) Biol Open 2022 Dec 15;11(12) 2 Citations |
1 | Feeding Formula Eliminates the Necessity of Bacterial Dysbiosis and Induces Inflammation and Injury in the Paneth Cell Disruption Murine NEC Model in an Osmolality-Dependent Manner. (Lueschow SR, Kern SL, Gong H, Grobe JL, Segar JL, Carlson SJ, McElroy SJ) Nutrients 2020 Mar 26;12(4) 10 Citations |
3 | Paneth cell defects in Crohn's disease patients promote dysbiosis. (Liu TC, Gurram B, Baldridge MT, Head R, Lam V, Luo C, Cao Y, Simpson P, Hayward M, Holtz ML, Bousounis P, Noe J, Lerner D, Cabrera J, Biank V, Stephens M, Huttenhower C, McGovern DP, Xavier RJ, Stappenbeck TS, Salzman NH) JCI Insight 2016 Jun 02;1(8):e86907 82 Citations |
1 | Dysbiosis--a consequence of Paneth cell dysfunction. (Salzman NH, Bevins CL) Semin Immunol 2013 Nov 30;25(5):334-41 76 Citations |
1 | Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. (Chu H, Pazgier M, Jung G, Nuccio SP, Castillo PA, de Jong MF, Winter MG, Winter SE, Wehkamp J, Shen B, Salzman NH, Underwood MA, Tsolis RM, Young GM, Lu W, Lehrer RI, Bäumler AJ, Bevins CL) Science 2012 Jul 27;337(6093):477-81 304 Citations |
1 | Alternative luminal activation mechanisms for paneth cell α-defensins. (Mastroianni JR, Costales JK, Zaksheske J, Selsted ME, Salzman NH, Ouellette AJ) J Biol Chem 2012 Mar 30;287(14):11205-12 34 Citations |
1 | Expansion of Paneth cell population in response to enteric Salmonella enterica serovar Typhimurium infection. (Martinez Rodriguez NR, Eloi MD, Huynh A, Dominguez T, Lam AH, Carcamo-Molina D, Naser Z, Desharnais R, Salzman NH, Porter E) Infect Immun 2012 Jan;80(1):266-75 54 Citations |
1 | Paneth cell defensins and the regulation of the microbiome: détente at mucosal surfaces. (Salzman NH) Gut Microbes 2010;1(6):401-6 97 Citations |
1 | Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis. (Bevins CL, Salzman NH) Nat Rev Microbiol 2011 May;9(5):356-68 859 Citations |
1 | Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa. (Salzman NH, Underwood MA, Bevins CL) Semin Immunol 2007 Apr;19(2):70-83 327 Citations |
1 | Reduced Paneth cell alpha-defensins in ileal Crohn's disease. (Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H Jr, Fellermann K, Ganz T, Stange EF, Bevins CL) Proc Natl Acad Sci U S A 2005 Dec 13;102(50):18129-34 828 Citations |
1 | Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. (Salzman NH, Ghosh D, Huttner KM, Paterson Y, Bevins CL) Nature 2003 Apr 03;422(6931):522-6 658 Citations |
1 | Enteric salmonella infection inhibits Paneth cell antimicrobial peptide expression. (Salzman NH, Chou MM, de Jong H, Liu L, Porter EM, Paterson Y) Infect Immun 2003 Mar;71(3):1109-15 122 Citations |
1 | Enteric defensin expression in necrotizing enterocolitis. (Salzman NH, Polin RA, Harris MC, Ruchelli E, Hebra A, Zirin-Butler S, Jawad A, Martin Porter E, Bevins CL) Pediatr Res 1998 Jul;44(1):20-6 114 Citations |