| 1 | A Mutation in the Transmembrane Domain of Adenylate Cyclase 3 Impairs Enzymatic Function to Cause Sex-Specific Depression- and Anxiety-Like Behaviors and Food Seeking in a Rat Model. (Fitzpatrick MK, Dyson C, Beeson A, Adrian L, Marrs G, Grzybowski M, Klotz J, Geurts AM, Chen R, Weiner JL, Solberg Woods LC) Genes Brain Behav 2025 Jun;24(3):e70028 |
| 2 | Probiotic and high-fat diet: effects on pain assessment, body composition, and cytokines in male and female adolescent and adult rats. (Raff H, Hainsworth KR, Woyach VL, Weihrauch D, Wang X, Dean C) Am J Physiol Regul Integr Comp Physiol 2024 Aug 01;327(2):R123-R132 3 Citations |
| 1 | The effects of conjugated linoleic acid supplementation on glycemic control, adipokines, cytokines, malondialdehyde and liver function enzymes in patients at risk of cardiovascular disease: a GRADE-assessed systematic review and dose-response meta-analysis. (Ghodoosi N, Rasaei N, Goudarzi K, Hashemzadeh M, Dolatshahi S, Omran HS, Amirani N, Ashtary-Larky D, Shimi G, Asbaghi O) Nutr J 2023 Oct 05;22(1):47 10 Citations |
| 1 | The effect of weight loss on hypothalamus structure and function in obese individuals: a systematic review and meta-analysis. (Devi S, Gedda DUK, Chawla S, Doucette J, Yadav N, Mirshahi S, de Moura LP, Velloso LA, Mekary RA) Int J Neurosci 2024 Jun;134(1):75-87 1 Citation |
| 1 | Regulation of cardiovascular health and disease by visceral adipose tissue-derived metabolic hormones. (Vasamsetti SB, Natarajan N, Sadaf S, Florentin J, Dutta P) J Physiol 2023 Jun;601(11):2099-2120 57 Citations |
| 5 | Melanocortin MC4R receptor is required for energy expenditure but not blood pressure effects of angiotensin II within the mouse brain. (Oliveira V, Riedl RA, Claflin KE, Mathieu NM, Ritter ML, Balapattabi K, Wackman KK, Reho JJ, Brozoski DT, Morgan DA, Cui H, Rahmouni K, Burnett CML, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL) Physiol Genomics 2022 Jun 01;54(6):196-205 7 Citations |
| 4 | Recent Advances in Hypertension: Intersection of Metabolic and Blood Pressure Regulatory Circuits in the Central Nervous System. (Oliveira V, Kwitek AE, Sigmund CD, Morselli LL, Grobe JL) Hypertension 2021 Apr;77(4):1061-1068 27 Citations |
| 1 | Behavioral, metabolic, and renal outcomes of 1-month isolation in adolescent male Dahl salt-sensitive rats. (Nikolaienko O, Isaeva E, Levchenko V, Palygin O, Staruschenko A) Am J Physiol Regul Integr Comp Physiol 2020 Dec 01;319(6):R684-R689 5 Citations |
| 1 | Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. (Yaghootkar H, Zhang Y, Spracklen CN, Karaderi T, Huang LO, Bradfield J, Schurmann C, Fine RS, Preuss MH, Kutalik Z, Wittemans LBL, Lu Y, Metz S, Willems SM, Li-Gao R, Grarup N, Wang S, Molnos S, Sandoval-Zárate AA, Nalls MA, Lange LA, Haesser J, Guo X, Lyytikäinen LP, Feitosa MF, Sitlani CM, Venturini C, Mahajan A, Kacprowski T, Wang CA, Chasman DI, Amin N, Broer L, Robertson N, Young KL, Allison M, Auer PL, Blüher M, Borja JB, Bork-Jensen J, Carrasquilla GD, Christofidou P, Demirkan A, Doege CA, Garcia ME, Graff M, Guo K, Hakonarson H, Hong J, Ida Chen YD, Jackson R, Jakupović H, Jousilahti P, Justice AE, Kähönen M, Kizer JR, Kriebel J, LeDuc CA, Li J, Lind L, Luan J, Mackey DA, Mangino M, Männistö S, Martin Carli JF, Medina-Gomez C, Mook-Kanamori DO, Morris AP, de Mutsert R, Nauck M, Prokic I, Pennell CE, Pradhan AD, Psaty BM, Raitakari OT, Scott RA, Skaaby T, Strauch K, Taylor KD, Teumer A, Uitterlinden AG, Wu Y, Yao J, Walker M, North KE, Kovacs P, Ikram MA, van Duijn CM, Ridker PM, Lye S, Homuth G, Ingelsson E, Spector TD, McKnight B, Province MA, Lehtimäki T, Adair LS, Rotter JI, Reiner AP, Wilson JG, Harris TB, Ripatti S, Grallert H, Meigs JB, Salomaa V, Hansen T, Willems van Dijk K, Wareham NJ, Grant SFA, Langenberg C, Frayling TM, Lindgren CM, Mohlke KL, Leibel RL, Loos RJF, Kilpeläinen TO) Diabetes 2020 Dec;69(12):2806-2818 43 Citations |
| 5 | Single-Nucleus RNA Sequencing of the Hypothalamic Arcuate Nucleus of C57BL/6J Mice After Prolonged Diet-Induced Obesity. (Deng G, Morselli LL, Wagner VA, Balapattabi K, Sapouckey SA, Knudtson KL, Rahmouni K, Cui H, Sigmund CD, Kwitek AE, Grobe JL) Hypertension 2020 Aug;76(2):589-597 33 Citations |
| 1 | Circadian Misalignment of the 24-hour Profile of Endocannabinoid 2-Arachidonoylglycerol (2-AG) in Obese Adults. (Hanlon EC, Leproult R, Stuhr KL, Doncheck EM, Hillard CJ, Van Cauter E) J Clin Endocrinol Metab 2020 Mar 01;105(3):792-802 13 Citations |
| 1 | Acute Blockade of PACAP-Dependent Activity in the Ventromedial Nucleus of the Hypothalamus Disrupts Leptin-Induced Behavioral and Molecular Changes in Rats. (Hurley MM, Anderson EM, Chen C, Maunze B, Hess EM, Block ME, Patel N, Cooper Z, McCoy R, Dabra T, Conley W, Reilly MJ, Hearing M, Choi S) Neuroendocrinology 2020;110(3-4):271-281 14 Citations |
| 1 | Preventive Effects by Black Raspberries of Endometrial Carcinoma Initiation and Promotion Induced by a High-Fat Diet. (Huang YW, Chen JH, Rader JS, Aguilera-Barrantes I, Wang LS) Mol Nutr Food Res 2019 Jun;63(12):e1900013 5 Citations |
| 1 | Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance. (Balsevich G, Sticht M, Bowles NP, Singh A, Lee TTY, Li Z, Chelikani PK, Lee FS, Borgland SL, Hillard CJ, McEwen BS, Hill MN) Proc Natl Acad Sci U S A 2018 Jul 17;115(29):7605-7610 41 Citations |
| 1 | Cardiovascular and Metabolic Consequences of Testosterone Supplements in Young and Old Male Spontaneously Hypertensive Rats: Implications for Testosterone Supplements in Men. (Dalmasso C, Patil CN, Yanes Cardozo LL, Romero DG, Maranon RO) J Am Heart Assoc 2017 Oct 17;6(10) 28 Citations |
| 2 | Potential mechanisms of hypothalamic renin-angiotensin system activation by leptin and DOCA-salt for the control of resting metabolism. (Sapouckey SA, Deng G, Sigmund CD, Grobe JL) Physiol Genomics 2017 Dec 01;49(12):722-732 24 Citations |
| 1 | Insulin sensitivity, leptin, adiponectin, resistin, and testosterone in adult male and female rats after maternal-neonatal separation and environmental stress. (Raff H, Hoeynck B, Jablonski M, Leonovicz C, Phillips JM, Gehrand AL) Am J Physiol Regul Integr Comp Physiol 2018 Jan 01;314(1):R12-R21 25 Citations |
| 1 | The temporal expression of adipokines during spinal fusion. (Virk S, Bertone AL, Hussein HH, Toth JM, Kaido M, Khan S) Spine J 2017 Dec;17(12):1897-1906 5 Citations |
| 2 | Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism. (Claflin KE, Sandgren JA, Lambertz AM, Weidemann BJ, Littlejohn NK, Burnett CM, Pearson NA, Morgan DA, Gibson-Corley KN, Rahmouni K, Grobe JL) J Clin Invest 2017 Apr 03;127(4):1414-1424 68 Citations |
| 1 | Obesity alters immune and metabolic profiles: New insight from obese-resistant mice on high-fat diet. (Boi SK, Buchta CM, Pearson NA, Francis MB, Meyerholz DK, Grobe JL, Norian LA) Obesity (Silver Spring) 2016 Oct;24(10):2140-9 64 Citations |
| 1 | Responses to drugs of abuse and non-drug rewards in leptin deficient ob/ob mice. (Muelbl MJ, Nawarawong NN, Clancy PT, Nettesheim CE, Lim YW, Olsen CM) Psychopharmacology (Berl) 2016 Jul;233(14):2799-811 23 Citations |
| 1 | Effect of selective expression of dominant-negative PPARγ in pro-opiomelanocortin neurons on the control of energy balance. (Stump M, Guo DF, Lu KT, Mukohda M, Liu X, Rahmouni K, Sigmund CD) Physiol Genomics 2016 Jul 01;48(7):491-501 17 Citations |
| 1 | Neonatal growth restriction-related leptin deficiency enhances leptin-triggered sympathetic activation and central angiotensin II receptor-dependent stress-evoked hypertension. (Peotta V, Rahmouni K, Segar JL, Morgan DA, Pitz KM, Rice OM, Roghair RD) Pediatr Res 2016 Aug;80(2):244-51 5 Citations |
| 2 | Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. (Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE) J Clin Invest 2015 Oct 01;125(10):3819-30 72 Citations |
| 1 | In Nonobese Girls, Waist Circumference as a Predictor of Insulin Resistance Is Comparable to MRI Fat Measures and Superior to BMI. (Wolfgram PM, Connor EL, Rehm JL, Eickhoff JC, Zha W, Reeder SB, Allen DB) Horm Res Paediatr 2015;84(4):258-65 16 Citations |
| 2 | Leptin attenuates the detrimental effects of β-amyloid on spatial memory and hippocampal later-phase long term potentiation in rats. (Tong JQ, Zhang J, Hao M, Yang J, Han YF, Liu XJ, Shi H, Wu MN, Liu QS, Qi JS) Horm Behav 2015 Jul;73:125-30 42 Citations |
| 1 | Olanzapine for cachexia in patients with advanced cancer: an exploratory study of effects on weight and metabolic cytokines. (Naing A, Dalal S, Abdelrahim M, Wheler J, Hess K, Fu S, Hong DS, Janku F, Falchook GS, Ilustre A, Ouyang F, Kurzrock R) Support Care Cancer 2015 Sep;23(9):2649-54 44 Citations |
| 1 | Circadian rhythm of circulating levels of the endocannabinoid 2-arachidonoylglycerol. (Hanlon EC, Tasali E, Leproult R, Stuhr KL, Doncheck E, de Wit H, Hillard CJ, Van Cauter E) J Clin Endocrinol Metab 2015 Jan;100(1):220-6 97 Citations |
| 1 | Umbilical cord plasma and salivary insulin and leptin concentrations in AGA neonates: a preliminary report. (Seal N, Siddiqui DS, Seal J, Bernhard KA, Williams S) J Matern Fetal Neonatal Med 2014 Nov;27(16):1716-8 1 Citation |
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| 2 | Intestinal microbiota determine severity of myocardial infarction in rats. (Lam V, Su J, Koprowski S, Hsu A, Tweddell JS, Rafiee P, Gross GJ, Salzman NH, Baker JE) FASEB J 2012 Apr;26(4):1727-35 305 Citations |
| 1 | Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. (Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD) PLoS Genet 2011 Oct;7(10):e1002323 61 Citations |
| 1 | The antiproliferative effects of pterostilbene on breast cancer in vitro are via inhibition of constitutive and leptin-induced Janus kinase/signal transducer and activator of transcription activation. (McCormack D, Schneider J, McDonald D, McFadden D) Am J Surg 2011 Nov;202(5):541-4 43 Citations |
| 2 | Repeated exposure to severely limited sleep results in distinctive and persistent physiological imbalances in rats. (Everson CA, Szabo A) PLoS One 2011;6(8):e22987 53 Citations |
| 1 | Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. (Harlan SM, Morgan DA, Agassandian K, Guo DF, Cassell MD, Sigmund CD, Mark AL, Rahmouni K) Circ Res 2011 Apr 01;108(7):808-12 135 Citations |
| 1 | Cholecystokinin knockout mice are resistant to high-fat diet-induced obesity. (Lo CM, King A, Samuelson LC, Kindel TL, Rider T, Jandacek RJ, Raybould HE, Woods SC, Tso P) Gastroenterology 2010 May;138(5):1997-2005 66 Citations |
| 1 | Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin. (Rahmouni K, Sigmund CD, Haynes WG, Mark AL) Diabetes 2009 Mar;58(3):536-42 185 Citations |
| 1 | Control of leptin with altitude exposure. (Raff H) J Appl Physiol (1985) 2008 Nov;105(5):1686-7 3 Citations |
| 1 | Epidermal growth factor and parathyroid hormone-related peptide mRNA in the mammary gland and their concentrations in milk: effects of postpartum hypoxia in lactating rats. (Bruder ED, Hoof JV, Young JB, Raff H) Horm Metab Res 2008 Jul;40(7):446-53 11 Citations |
| 1 | Nonalcoholic Fatty gallbladder disease: the influence of diet in lean and obese mice. (Goldblatt MI, Swartz-Basile DA, Al-Azzawi HH, Tran KQ, Nakeeb A, Pitt HA) J Gastrointest Surg 2006 Feb;10(2):193-201 24 Citations |
| 1 | Plasma leptin and ghrelin in the neonatal rat: interaction of dexamethasone and hypoxia. (Bruder ED, Jacobson L, Raff H) J Endocrinol 2005 Jun;185(3):477-84 30 Citations |
| 1 | Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome. (Fath MA, Mullins RF, Searby C, Nishimura DY, Wei J, Rahmouni K, Davis RE, Tayeh MK, Andrews M, Yang B, Sigmund CD, Stone EM, Sheffield VC) Hum Mol Genet 2005 May 01;14(9):1109-18 168 Citations |
| 1 | Leptin-resistant obese mice do not form biliary crystals on a high cholesterol diet. (Graewin SJ, Lee KH, Tran KQ, Goldblatt MI, Svatek CL, Nakeeb A, Pitt HA) J Surg Res 2004 Dec;122(2):145-9 10 Citations |
| 1 | Reductions in circulating anabolic hormones induced by sustained sleep deprivation in rats. (Everson CA, Crowley WR) Am J Physiol Endocrinol Metab 2004 Jun;286(6):E1060-70 186 Citations |
| 1 | Adipose depot-specific modulation of angiotensinogen gene expression in diet-induced obesity. (Rahmouni K, Mark AL, Haynes WG, Sigmund CD) Am J Physiol Endocrinol Metab 2004 Jun;286(6):E891-5 105 Citations |
| 1 | Diabetes and hyperlipidemia correlate with gallbladder contractility in leptin-related murine obesity. (Tran KQ, Goldblatt MI, Swartz-Basile DA, Svatek C, Nakeeb A, Pitt HA) J Gastrointest Surg 2003 Nov;7(7):857-62; discussion 863 42 Citations |
| 1 | Decreased gallbladder response in leptin-deficient obese mice. (Goldblatt MI, Swartz-Basile DA, Svatek CL, Nakeeb A, Pitt HA) J Gastrointest Surg 2002;6(3):438-42; discussion 443-4 55 Citations |
| 1 | Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms. (Zhang P, Klenk ES, Lazzaro MA, Williams LB, Considine RV) Endocrinology 2002 Jan;143(1):99-106 39 Citations |
| 1 | Effect of neonatal hypoxia on leptin, insulin, growth hormone and body composition in the rat. (Raff H, Bruder ED, Jankowski BM, Colman RJ) Horm Metab Res 2001 Mar;33(3):151-5 54 Citations |
| 1 | Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice. (Mark AL, Shaffer RA, Correia ML, Morgan DA, Sigmund CD, Haynes WG) J Hypertens 1999 Dec;17(12 Pt 2):1949-53 242 Citations |
| 1 | The effect of hypoxia on plasma leptin and insulin in newborn and juvenile rats. (Raff H, Bruder ED, Jankowski BM) Endocrine 1999 Aug;11(1):37-9 54 Citations |
| 1 | Sympathetic inhibition, leptin, and uncoupling protein subtype expression in normal fasting rats. (Sivitz WI, Fink BD, Morgan DA, Fox JM, Donohoue PA, Haynes WG) Am J Physiol 1999 Oct;277(4):E668-77 53 Citations |
| 1 | Fasting and leptin modulate adipose and muscle uncoupling protein: divergent effects between messenger ribonucleic acid and protein expression. (Sivitz WI, Fink BD, Donohoue PA) Endocrinology 1999 Apr;140(4):1511-9 99 Citations |
