| 1 | Chromosome 2 Fragment Substitutions in Dahl Salt-Sensitive Rats and RNA Sequencing Identified Enpep and Hs2st1 as Vascular Inflammatory Modulators. (Berillo O, Ouerd S, Idris-Khodja N, Rehman A, Richer C, Sinnett D, Kwitek AE, Paradis P, Schiffrin EL) Hypertension 2021 Jan;77(1):178-189 6 Citations |
| 3 | Mapping genetic modifiers of radiation-induced cardiotoxicity to rat chromosome 3. (Schlaak RA, Frei A, Schottstaedt AM, Tsaih SW, Fish BL, Harmann L, Liu Q, Gasperetti T, Medhora M, North PE, Strande JL, Sun Y, Rui H, Flister MJ, Bergom C) Am J Physiol Heart Circ Physiol 2019 Jun 01;316(6):H1267-H1280 37 Citations |
| 1 | A High-Resolution Genetic Map for the Laboratory Rat. (Littrell J, Tsaih SW, Baud A, Rastas P, Solberg-Woods L, Flister MJ) G3 (Bethesda) 2018 Jul 02;8(7):2241-2248 14 Citations |
| 1 | Genome-wide map of proximity linkage to renin proximal promoter in rat. (Stodola TJ, Liu P, Liu Y, Vallejos AK, Geurts AM, Greene AS, Liang M) Physiol Genomics 2018 May 01;50(5):323-331 8 Citations |
| 1 | Congenic Strains Confirm the Pleiotropic Effect of Chromosome 4 QTL on Mouse Femoral Geometry and Biomechanical Performance. (Kristianto J, Litscher SJ, Johnson MG, Patel F, Patel M, Fisher J, Zastrow RK, Radcliff AB, Blank RD) PLoS One 2016;11(2):e0148571 6 Citations |
| 2 | Pappa2 is linked to salt-sensitive hypertension in Dahl S rats. (Cowley AW Jr, Yang C, Kumar V, Lazar J, Jacob H, Geurts AM, Liu P, Dayton A, Kurth T, Liang M) Physiol Genomics 2016 Jan;48(1):62-72 34 Citations |
| 2 | A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells. (Tsaih SW, Presa M, Khaja S, Ciecko AE, Serreze DV, Chen YG) Genes Immun 2015;16(3):221-30 7 Citations |
| 1 | Systems biology with high-throughput sequencing reveals genetic mechanisms underlying the metabolic syndrome in the Lyon hypertensive rat. (Wang J, Ma MC, Mennie AK, Pettus JM, Xu Y, Lin L, Traxler MG, Jakoubek J, Atanur SS, Aitman TJ, Xing Y, Kwitek AE) Circ Cardiovasc Genet 2015 Apr;8(2):316-26 18 Citations |
| 1 | Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma. (Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, Kozlov S, Mao JH, Van Dyke T, Kwok PY, Khan J, Balmain A, Fan Q, Weiss WA) Cell Rep 2014 Nov 06;9(3):1034-46 32 Citations |
| 2 | FMRI and fcMRI phenotypes map the genomic effect of chromosome 13 in Brown Norway and Dahl salt-sensitive rats. (Li Z, Ward BD, Dwinell MR, Lombard JH, Pawela CP) Neuroimage 2014 Apr 15;90:403-12 5 Citations |
| 2 | Analysis of disease-associated objects at the Rat Genome Database. (Wang SJ, Laulederkind SJ, Hayman GT, Smith JR, Petri V, Lowry TF, Nigam R, Dwinell MR, Worthey EA, Munzenmaier DH, Shimoyama M, Jacob HJ) Database (Oxford) 2013;2013:bat046 8 Citations |
| 2 | Genetic control of murine invariant natural killer T cells maps to multiple type 1 diabetes regions. (Tsaih SW, Khaja S, Ciecko AE, MacKinney E, Chen YG) Genes Immun 2013 Sep;14(6):380-6 4 Citations |
| 3 | Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats. (Basile DP, Dwinell MR, Wang SJ, Shames BD, Donohoe DL, Chen S, Sreedharan R, Van Why SK) Kidney Int 2013 Feb;83(2):242-50 21 Citations |
| 1 | Identification of a region of rat chromosome 1 that impairs the myogenic response and autoregulation of cerebral blood flow in fawn-hooded hypertensive rats. (Pabbidi MR, Juncos J, Juncos L, Renic M, Tullos HJ, Lazar J, Jacob HJ, Harder DR, Roman RJ) Am J Physiol Heart Circ Physiol 2013 Jan 15;304(2):H311-7 19 Citations |
| 1 | Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock rats. (Solberg Woods LC, Holl KL, Oreper D, Xie Y, Tsaih SW, Valdar W) Physiol Genomics 2012 Nov 01;44(21):1013-26 38 Citations |
| 1 | Identification of hypertension susceptibility loci on rat chromosome 12. (Flister MJ, Prisco SZ, Sarkis AB, O'Meara CC, Hoffman M, Wendt-Andrae J, Moreno C, Lazar J, Jacob HJ) Hypertension 2012 Oct;60(4):942-8 23 Citations |
| 1 | Using bioinformatics and systems genetics to dissect HDL-cholesterol genetics in an MRL/MpJ x SM/J intercross. (Leduc MS, Blair RH, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B) J Lipid Res 2012 Jun;53(6):1163-75 11 Citations |
| 1 | Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density. (Ackert-Bicknell CL, Demissie S, Tsaih SW, Beamer WG, Cupples LA, Paigen BJ, Hsu YH, Kiel DP, Karasik D) Bone 2012 May;50(5):1188-95 14 Citations |
| 1 | Comprehensive skeletal phenotyping and linkage mapping in an intercross of recombinant congenic mouse strains HcB-8 and HcB-23. (Saless N, Litscher SJ, Houlihan MJ, Han IK, Wilson D, Demant P, Blank RD) Cells Tissues Organs 2011;194(2-4):244-8 10 Citations |
| 1 | Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice. (Leduc MS, Hageman RS, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B) J Lipid Res 2011 Sep;52(9):1672-82 22 Citations |
| 1 | Unmasking genes in a type 1 diabetes-resistant mouse strain that enhances pathogenic CD8 T-cell responses. (Driver JP, Chen YG, Zhang W, Asrat S, Serreze DV) Diabetes 2011 Apr;60(4):1354-9 6 Citations |
| 1 | Narrowing a region on rat chromosome 13 that protects against hypertension in Dahl SS-13BN congenic strains. (Moreno C, Williams JM, Lu L, Liang M, Lazar J, Jacob HJ, Cowley AW Jr, Roman RJ) Am J Physiol Heart Circ Physiol 2011 Apr;300(4):H1530-5 29 Citations |
| 2 | Vascular responses in aortic rings of a consomic rat panel derived from the Fawn Hooded Hypertensive strain. (Kunert MP, Dwinell MR, Lombard JH) Physiol Genomics 2010 Nov 29;42A(4):244-58 8 Citations |
| 1 | Sequence variation at multiple loci influences red cell hemoglobin concentration. (Peters LL, Shavit JA, Lambert AJ, Tsaih SW, Li Q, Su Z, Leduc MS, Paigen B, Churchill GA, Ginsburg D, Brugnara C) Blood 2010 Dec 16;116(25):e139-49 10 Citations |
| 1 | Dynamic convergence and divergence of renal genomic and biological pathways in protection from Dahl salt-sensitive hypertension. (Lu L, Li P, Yang C, Kurth T, Misale M, Skelton M, Moreno C, Roman RJ, Greene AS, Jacob HJ, Lazar J, Liang M, Cowley AW Jr) Physiol Genomics 2010 Mar 03;41(1):63-70 29 Citations |
| 2 | Differential effects of leptin receptor mutation on male and female BBDR Gimap5-/Gimap5- spontaneously diabetic rats. (Moralejo DH, Hansen CT, Treuting P, Hessner MJ, Fuller JM, Van Yserloo B, Jensen R, Osborne W, Kwitek AE, Lernmark A) Physiol Genomics 2010 Mar 03;41(1):9-20 9 Citations |
| 1 | Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains. (Wiessner JH, Garrett MR, Roman RJ, Mandel NS) Am J Physiol Renal Physiol 2009 Aug;297(2):F301-6 4 Citations |
| 1 | Quantitative trait loci for biomechanical performance and femoral geometry in an intercross of recombinant congenic mice: restriction of the Bmd7 candidate interval. (Saless N, Litscher SJ, Lopez Franco GE, Houlihan MJ, Sudhakaran S, Raheem KA, O'Neil TK, Vanderby R, Demant P, Blank RD) FASEB J 2009 Jul;23(7):2142-54 24 Citations |
| 1 | Congenic strains provide evidence that four mapped loci in chromosomes 2, 4, and 16 influence hypertension in the SHR. (Aneas I, Rodrigues MV, Pauletti BA, Silva GJ, Carmona R, Cardoso L, Kwitek AE, Jacob HJ, Soler JM, Krieger JE) Physiol Genomics 2009 Mar 03;37(1):52-7 17 Citations |
| 2 | Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross. (Kunert MP, Dwinell MR, Drenjancevic Peric I, Lombard JH) Am J Physiol Regul Integr Comp Physiol 2008 Aug;295(2):R516-27 11 Citations |
| 2 | Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic rats. (Liang M, Lee NH, Wang H, Greene AS, Kwitek AE, Kaldunski ML, Luu TV, Frank BC, Bugenhagen S, Jacob HJ, Cowley AW Jr) Physiol Genomics 2008 Jun 12;34(1):54-64 43 Citations |
| 1 | Effects of chromosome 17 on features of the metabolic syndrome in the Lyon hypertensive rat. (Gilibert S, Kwitek AE, Hubner N, Tschannen M, Jacob HJ, Sassard J, Bataillard A) Physiol Genomics 2008 Apr 22;33(2):212-7 16 Citations |
| 1 | Quantitative trait loci associated with blood pressure of metabolic syndrome in the progeny of NZO/HILtJxC3H/HeJ intercrosses. (Nishihara E, Tsaih SW, Tsukahara C, Langley S, Sheehan S, DiPetrillo K, Kunita S, Yagami K, Churchill GA, Paigen B, Sugiyama F) Mamm Genome 2007 Aug;18(8):573-83 10 Citations |
| 1 | Differences in cardiovascular sensitivity to propofol in a chromosome substitution rat model. (Stekiel TA, Weber CA, Contney SJ, Bosnjak ZJ) Croat Med J 2007 Jun;48(3):312-8 8 Citations |
| 2 | Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. (Geurts AM, Collier LS, Geurts JL, Oseth LL, Bell ML, Mu D, Lucito R, Godbout SA, Green LE, Lowe SW, Hirsch BA, Leinwand LA, Largaespada DA) PLoS Genet 2006 Sep 29;2(9):e156 85 Citations |
| 1 | Complex genetic architecture revealed by analysis of high-density lipoprotein cholesterol in chromosome substitution strains and F2 crosses. (Stylianou IM, Tsaih SW, DiPetrillo K, Ishimori N, Li R, Paigen B, Churchill G) Genetics 2006 Oct;174(2):999-1007 29 Citations |
| 4 | Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. (Kunert MP, Drenjancevic-Peric I, Dwinell MR, Lombard JH, Cowley AW Jr, Greene AS, Kwitek AE, Jacob HJ) Physiol Genomics 2006 Aug 16;26(3):218-25 25 Citations |
| 1 | Structure-based prediction of insertion-site preferences of transposons into chromosomes. (Geurts AM, Hackett CS, Bell JB, Bergemann TL, Collier LS, Carlson CM, Largaespada DA, Hackett PB) Nucleic Acids Res 2006;34(9):2803-11 66 Citations |
| 1 | NADPH oxidase in the renal medulla causes oxidative stress and contributes to salt-sensitive hypertension in Dahl S rats. (Taylor NE, Glocka P, Liang M, Cowley AW Jr) Hypertension 2006 Apr;47(4):692-8 175 Citations |
| 1 | Chromosomal substitution-dependent differences in cardiovascular responses to sodium pentobarbital. (Stekiel TA, Contney SJ, Bosnjak ZJ, Kampine JP, Roman RJ, Stekiel WJ) Anesth Analg 2006 Mar;102(3):799-805 9 Citations |
| 1 | Plasma cell tumour progression in iMycEmu gene-insertion mice. (Kim JS, Han SS, Park SS, McNeil N, Janz S) J Pathol 2006 May;209(1):44-55 10 Citations |
| 1 | Arteriolar responses to vasodilator stimuli and elevated P(O2) in renin congenic and Dahl salt-sensitive rats. (Drenjancevic-Peric I, Greene AS, Kunert MP, Lombard JH) Microcirculation 2004 Dec;11(8):669-77 15 Citations |
| 1 | Substitution of chromosome 1 ameliorates L-NAME hypertension and renal disease in the fawn-hooded hypertensive rat. (Mattson DL, Kunert MP, Roman RJ, Jacob HJ, Cowley AW Jr) Am J Physiol Renal Physiol 2005 May;288(5):F1015-22 30 Citations |
| 1 | Deregulated expression of the Myc cellular oncogene drives development of mouse "Burkitt-like" lymphomas from naive B cells. (Zhu D, Qi CF, Morse HC 3rd, Janz S, Stevenson FK) Blood 2005 Mar 01;105(5):2135-7 35 Citations |
| 2 | Mapping the genetic determinants of hypertension, metabolic diseases, and related phenotypes in the lyon hypertensive rat. (Bilusic M, Bataillard A, Tschannen MR, Gao L, Barreto NE, Vincent M, Wang T, Jacob HJ, Sassard J, Kwitek AE) Hypertension 2004 Nov;44(5):695-701 50 Citations |
| 1 | Genome sequence of the Brown Norway rat yields insights into mammalian evolution. (Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Simons R, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium) Nature 2004 Apr 01;428(6982):493-521 1823 Citations |
| 1 | Genetic analysis of blood pressure in C3H/HeJ and SWR/J mice. (DiPetrillo K, Tsaih SW, Sheehan S, Johns C, Kelmenson P, Gavras H, Churchill GA, Paigen B) Physiol Genomics 2004 Apr 13;17(2):215-20 48 Citations |
| 1 | BCL2 accelerates inflammation-induced BALB/c plasmacytomas and promotes novel tumors with coexisting T(12;15) and T(6;15) translocations. (Silva S, Kovalchuk AL, Kim JS, Klein G, Janz S) Cancer Res 2003 Dec 15;63(24):8656-63 26 Citations |
| 1 | Influence of diet and genetics on hypertension and renal disease in Dahl salt-sensitive rats. (Mattson DL, Kunert MP, Kaldunski ML, Greene AS, Roman RJ, Jacob HJ, Cowley AW Jr) Physiol Genomics 2004 Jan 15;16(2):194-203 74 Citations |
