Medical College of Wisconsin
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Publications indexed to the term Capsid Proteins

FacultyTitle
1Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibody evasion. (Kellish PC, Marsic D, Crosson SM, Choudhury S, Scalabrino ML, Strang CE, Hill J, McCullough KT, Peterson JJ, Fajardo D, Gupte S, Makal V, Kondratov O, Kondratova L, Iyer S, Witherspoon CD, Gamlin PD, Zolotukhin S, Boye SL, Boye SE) Mol Ther 2023 Dec 06;31(12):3441-3456       24 Citations
1Improving retinal vascular endothelial cell tropism through rational rAAV capsid design. (Periasamy R, Patel DD, Boye SL, Boye SE, Lipinski DM) PLoS One 2023;18(5):e0285370       4 Citations
1Strain-Specific Interactions between the Viral Capsid Proteins VP4, VP7 and VP6 Influence Rescue of Rotavirus Reassortants by Reverse Genetics. (Valusenko-Mehrkens R, Gadicherla AK, Johne R, Falkenhagen A) Int J Mol Sci 2023 Mar 16;24(6)       9 Citations
1Tough Way In, Tough Way Out: The Complex Interplay of Host and Viral Factors in Nucleocytoplasmic Trafficking during HIV-1 Infection. (Sarkar S, Balakrishnan K, Chintala K, Mohareer K, Luedde T, Vasudevan AAJ, Münk C, Banerjee S) Viruses 2022 Nov 12;14(11)       12 Citations
2Diffuse interstitial pneumonia-like/macrophage activation syndrome-like changes in patients with COVID-19 correlate with length of illness. (Felix JC, Sheinin YM, Suster D, Ronen N, Ratiani M, Vanden Heuvel T, Winge E, Patton MD, Rau MJ, Ge L, Sun Y, Udhane SS, Langenheim JF, Rui H) Ann Diagn Pathol 2021 Aug;53:151744       5 Citations
1Generation of Simian Rotavirus Reassortants with VP4- and VP7-Encoding Genome Segments from Human Strains Circulating in Africa Using Reverse Genetics. (Falkenhagen A, Patzina-Mehling C, Gadicherla AK, Strydom A, O'Neill HG, Johne R) Viruses 2020 Feb 11;12(2)       32 Citations
1An Examination of HPV16 Natural Immunity in Men Who Have Sex with Men (MSM) in the HPV in Men (HIM) Study. (Beachler DC, Pinto LA, Kemp TJ, Nyitray AG, Hildesheim A, Viscidi R, Schussler J, Kreimer AR, Giuliano AR) Cancer Epidemiol Biomarkers Prev 2018 Apr;27(4):496-502       25 Citations
1Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo. (De Silva SR, Charbel Issa P, Singh MS, Lipinski DM, Barnea-Cramer AO, Walker NJ, Barnard AR, Hankins MW, MacLaren RE) Gene Ther 2016 Nov;23(11):767-774       29 Citations
1Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection. (Lipinski DM, Reid CA, Boye SL, Peterson JJ, Qi X, Boye SE, Boulton ME, Hauswirth WW) Hum Gene Ther 2015 Nov;26(11):767-76       15 Citations
1Solid-State NMR-Restrained Ensemble Dynamics of a Membrane Protein in Explicit Membranes. (Cheng X, Jo S, Qi Y, Marassi FM, Im W) Biophys J 2015 Apr 21;108(8):1954-62       11 Citations
1NMR-based simulation studies of Pf1 coat protein in explicit membranes. (Cheng X, Jo S, Marassi FM, Im W) Biophys J 2013 Aug 06;105(3):691-8       20 Citations
1Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA. (Zhang H, Endrizzi JA, Shu Y, Haque F, Sauter C, Shlyakhtenko LS, Lyubchenko Y, Guo P, Chi YI) RNA 2013 Sep;19(9):1226-37       121 Citations
1Human cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection. (Savaryn JP, Reitsma JM, Bigley TM, Halligan BD, Qian Z, Yu D, Terhune SS) J Virol 2013 Mar;87(5):2463-74       29 Citations
1Structure and dynamics of the membrane-bound form of Pf1 coat protein: implications of structural rearrangement for virus assembly. (Park SH, Marassi FM, Black D, Opella SJ) Biophys J 2010 Sep 08;99(5):1465-74       68 Citations
1Generation of cytotoxic T-cell lines using overlapping pentadecapeptides derived from conserved regions of the adenovirus hexon protein. (Zhu F, Xu H, Tsao A, Margolis DA, Keever-Taylor CA) J Gen Virol 2010 Jun;91(Pt 6):1577-89       5 Citations
1Mechanism of action of cyclophilin a explored by metadynamics simulations. (Leone V, Lattanzi G, Molteni C, Carloni P) PLoS Comput Biol 2009 Mar;5(3):e1000309       41 Citations
1Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. (Moorman NJ, Cristea IM, Terhune SS, Rout MP, Chait BT, Shenk T) Cell Host Microbe 2008 Apr 17;3(4):253-62       181 Citations
1Human cytomegalovirus UL38 protein blocks apoptosis. (Terhune S, Torigoi E, Moorman N, Silva M, Qian Z, Shenk T, Yu D) J Virol 2007 Apr;81(7):3109-23       144 Citations
1Dipolar waves map the structure and topology of helices in membrane proteins. (Mesleh MF, Lee S, Veglia G, Thiriot DS, Marassi FM, Opella SJ) J Am Chem Soc 2003 Jul 23;125(29):8928-35       91 Citations
1Simultaneous assignment and structure determination of a membrane protein from NMR orientational restraints. (Marassi FM, Opella SJ) Protein Sci 2003 Mar;12(3):403-11       170 Citations
1Hsp90 phosphorylation is linked to its chaperoning function. Assembly of the reovirus cell attachment protein. (Zhao YG, Gilmore R, Leone G, Coffey MC, Weber B, Lee PW) J Biol Chem 2001 Aug 31;276(35):32822-7       93 Citations
1Detection of adenovirus DNA in peripheral blood mononuclear cells by polymerase chain reaction assay. (Flomenberg P, Gutierrez E, Piaskowski V, Casper JT) J Med Virol 1997 Mar;51(3):182-8       49 Citations
1Co-translational trimerization of the reovirus cell attachment protein. (Gilmore R, Coffey MC, Leone G, McLure K, Lee PW) EMBO J 1996 Jun 03;15(11):2651-8       44 Citations
1C-terminal trimerization, but not N-terminal trimerization, of the reovirus cell attachment protein Is a posttranslational and Hsp70/ATP-dependent process. (Leone G, Coffey MC, Gilmore R, Duncan R, Maybaum L, Lee PW) J Biol Chem 1996 Apr 05;271(14):8466-71       26 Citations
2Spontaneous, persistent infection of a B-cell lymphoma with adenovirus. (Flomenberg P, Piaskowski V, Harb J, Segura A, Casper JT) J Med Virol 1996 Mar;48(3):267-72       31 Citations
1Binding of reovirus to receptor leads to conformational changes in viral capsid proteins that are reversible upon virus detachment. (Fernandes J, Tang D, Leone G, Lee PW) J Biol Chem 1994 Jun 24;269(25):17043-7       25 Citations
1Reovirus protein sigma 1: from cell attachment to protein oligomerization and folding mechanisms. (Lee PW, Leone G) Bioessays 1994 Mar;16(3):199-206       10 Citations
1The reovirus cell attachment protein possesses two independently active trimerization domains: basis of dominant negative effects. (Leone G, Maybaum L, Lee PW) Cell 1992 Oct 30;71(3):479-88       39 Citations
1Trimerization of the reovirus cell attachment protein (sigma 1) induces conformational changes in sigma 1 necessary for its cell-binding function. (Leone G, Duncan R, Lee PW) Virology 1991 Oct;184(2):758-61       19 Citations
1Biochemical and biophysical characterization of the reovirus cell attachment protein sigma 1: evidence that it is a homotrimer. (Strong JE, Leone G, Duncan R, Sharma RK, Lee PW) Virology 1991 Sep;184(1):23-32       64 Citations
1Conformational and functional analysis of the C-terminal globular head of the reovirus cell attachment protein. (Duncan R, Horne D, Strong JE, Leone G, Pon RT, Yeung MC, Lee PW) Virology 1991 Jun;182(2):810-9       38 Citations
1The N-terminal heptad repeat region of reovirus cell attachment protein sigma 1 is responsible for sigma 1 oligomer stability and possesses intrinsic oligomerization function. (Leone G, Duncan R, Mah DC, Price A, Cashdollar LW, Lee PW) Virology 1991 May;182(1):336-45       36 Citations
1The incorporation of reovirus cell attachment protein sigma 1 into virions requires the N-terminal hydrophobic tail and the adjacent heptad repeat region. (Leone G, Mah DC, Lee PW) Virology 1991 May;182(1):346-50       34 Citations
1The N-terminal quarter of reovirus cell attachment protein sigma 1 possesses intrinsic virion-anchoring function. (Mah DC, Leone G, Jankowski JM, Lee PW) Virology 1990 Nov;179(1):95-103       37 Citations
1Resistance of human cells to the adenovirus E3 effect on class I MHC antigen expression. Implications for antiviral immunity. (Routes JM, Cook JL) J Immunol 1990 Apr 01;144(7):2763-70       20 Citations