Medical College of Wisconsin
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Publications indexed to the term Oxidoreductases Acting on CH-CH Group Donors

FacultyTitle
1Cryo-EM captures the coordination of asymmetric electron transfer through a di-copper site in DPOR. (Kashyap R, Walsh N, Deveryshetty J, Tokmina-Lukaszewska M, Zhao K, Gan YJ, Hoffman BM, Sarangi R, Bothner B, Bennett B, Antony E) Nat Commun 2025 Apr 24;16(1):3866       2 Citations
1Substrate recognition induces sequential electron transfer across subunits in the nitrogenase-like DPOR complex. (Corless EI, Bennett B, Antony E) J Biol Chem 2020 Sep 25;295(39):13630-13639       9 Citations
1Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed. (Tint GS, Pan L, Shang Q, Sharpe LJ, Brown AJ, Li M, Yu H) Dev Neurosci 2014;36(2):132-42       4 Citations
1Two distinct proton donors at the active site of Escherichia coli 2,4-dienoyl-CoA reductase are responsible for the formation of different products. (Tu X, Hubbard PA, Kim JJ, Schulz H) Biochemistry 2008 Jan 29;47(4):1167-75       15 Citations
1Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice. (Yu H, Li M, Tint GS, Chen J, Xu G, Patel SB) BMC Dev Biol 2007 Apr 04;7:27       10 Citations
12-methylbutyryl-CoA dehydrogenase deficiency in Hmong infants identified by expanded newborn screen. (van Calcar SC, Gleason LA, Lindh H, Hoffman G, Rhead W, Vockley G, Wolff JA, Durkin MS) WMJ 2007 Feb;106(1):12-5       33 Citations
1The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols. (Tint GS, Yu H, Shang Q, Xu G, Patel SB) J Lipid Res 2006 Jul;47(7):1535-41       89 Citations
1Recent insights into the Smith-Lemli-Opitz syndrome. (Yu H, Patel SB) Clin Genet 2005 Nov;68(5):383-91       81 Citations
2X-ray structure of Arabidopsis At1g77680, 12-oxophytodienoate reductase isoform 1. (Fox BG, Malone TE, Johnson KA, Madson SE, Aceti D, Bingman CA, Blommel PG, Buchan B, Burns B, Cao J, Cornilescu C, Doreleijers J, Ellefson J, Frederick R, Geetha H, Hruby D, Jeon WB, Kimball T, Kunert J, Markley JL, Newman C, Olson A, Peterson FC, Phillips GN Jr, Primm J, Ramirez B, Rosenberg NS, Runnels M, Seder K, Shaw J, Smith DW, Sreenath H, Song J, Sussman MR, Thao S, Troestler D, Tyler E, Tyler R, Ulrich E, Vinarov D, Vojtik F, Volkman BF, Wesenberg G, Wrobel RL, Zhang J, Zhao Q, Zolnai Z) Proteins 2005 Oct 01;61(1):206-8       10 Citations
1Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression. (Yu H, Wessels A, Tint GS, Patel SB) Brain Res Dev Brain Res 2005 Apr 21;156(1):46-60       15 Citations
1Crystal structures of human glutaryl-CoA dehydrogenase with and without an alternate substrate: structural bases of dehydrogenation and decarboxylation reactions. (Fu Z, Wang M, Paschke R, Rao KS, Frerman FE, Kim JJ) Biochemistry 2004 Aug 03;43(30):9674-84       81 Citations
1Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. (Yu H, Wessels A, Chen J, Phelps AL, Oatis J, Tint GS, Patel SB) BMC Dev Biol 2004 Feb 02;4:1       28 Citations
1Structures of isobutyryl-CoA dehydrogenase and enzyme-product complex: comparison with isovaleryl- and short-chain acyl-CoA dehydrogenases. (Battaile KP, Nguyen TV, Vockley J, Kim JJ) J Biol Chem 2004 Apr 16;279(16):16526-34       63 Citations
1The crystal structure and reaction mechanism of Escherichia coli 2,4-dienoyl-CoA reductase. (Hubbard PA, Liang X, Schulz H, Kim JJ) J Biol Chem 2003 Sep 26;278(39):37553-60       56 Citations
17-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. (Fitzky BU, Moebius FF, Asaoka H, Waage-Baudet H, Xu L, Xu G, Maeda N, Kluckman K, Hiller S, Yu H, Batta AK, Shefer S, Chen T, Salen G, Sulik K, Simoni RD, Ness GC, Glossmann H, Patel SB, Tint GS) J Clin Invest 2001 Sep;108(6):905-15       151 Citations
1Spectrum of Delta(7)-dehydrocholesterol reductase mutations in patients with the Smith-Lemli-Opitz (RSH) syndrome. (Yu H, Lee MH, Starck L, Elias ER, Irons M, Salen G, Patel SB, Tint GS) Hum Mol Genet 2000 May 22;9(9):1385-91       98 Citations
1Analysis of carnitine esters by radio-high performance liquid chromatography in cultured skin fibroblasts from patients with mitochondrial fatty acid oxidation disorders. (Schmidt-Sommerfeld E, Bobrowski PJ, Penn D, Rhead WJ, Wanders RJ, Bennett MJ) Pediatr Res 1998 Aug;44(2):210-4       17 Citations
1Catalytic defect of medium-chain acyl-coenzyme A dehydrogenase deficiency. Lack of both cofactor responsiveness and biochemical heterogeneity in eight patients. (Amendt BA, Rhead WJ) J Clin Invest 1985 Sep;76(3):963-9       14 Citations
1Novel tritium release assays for isovaleryl-CoA and butyryl-CoA dehydrogenases. (Rhead WJ, Hall CL, Tanaka K) J Biol Chem 1981 Feb 25;256(4):1616-24       19 Citations
1Isovaleryl-CoA dehydrogenase: demonstration in rat liver mitochondria by ion exchange chromatography and isoelectric focusing. (Noda C, Rhead WJ, Tanaka K) Proc Natl Acad Sci U S A 1980 May;77(5):2646-50       22 Citations