Medical College of Wisconsin
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Publications indexed to the term Adaptor Proteins, Signal Transducing

FacultyTitle
1Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum. (Lee DSM, Cardone KM, Zhang DY, Tsao NL, Abramowitz S, Sharma P, DePaolo JS, Conery M, Aragam KG, Biddinger K, Dikilitas O, Hoffman-Andrews L, Judy RL, Khan A, Kullo IJ, Puckelwartz MJ, Reza N, Satterfield BA, Singhal P, Penn Medicine Biobank, Arany Z, Cappola TP, Carruth ED, Day SM, Do R, Haggerty CM, Joseph J, McNally EM, Nadkarni G, Owens AT, Rader DJ, Ritchie MD, Sun YV, Voight BF, Levin MG, Damrauer SM) Nat Genet 2025 Apr;57(4):829-838       6 Citations
1Targeted degradation of GOLM1 by CC-885 via CRL4-CRBN E3 ligase inhibits hepatocellular carcinoma progression. (He J, Guo J, Liu S, Li H, Ma Y, Ma S, Hu Z, Zhao W, Tan M, Liu W, Liu B) Cell Signal 2025 Jun;130:111665       2 Citations
1Identification of MORF4L1 as an endogenous substrate of CRBN and its potential role as a therapeutic target in cancer. (Zhang L, Liu S, He J, Hu Z, Zhu L, Huang H, Gao Q, Wang D, Chen L, Zhang X, Liu R, Wang J, Song Y, Zeng K, Li X, Chen Y, Zou X, Ma S, Wang X, Xu G, Liu W, Liu B) Sci Rep 2025 Jan 18;15(1):2384       4 Citations
1Recurrent RhoGAP gene fusion CLDN18-ARHGAP26 promotes RHOA activation and focal adhesion kinase and YAP-TEAD signalling in diffuse gastric cancer. (Zhang F, Sahu V, Peng K, Wang Y, Li T, Bala P, Aitymbayev D, Sahgal P, Schaefer A, Der CJ, Ryeom S, Yoon S, Sethi N, Bass AJ, Zhang H) Gut 2024 Jul 11;73(8):1280-1291       17 Citations
1Novel PI(3)K-p85α/p110δ-ITK-LAT-PLC-γ2 and Fyn-ADAP-Carma1-TAK1 Pathways Define Reverse Signaling via FasL. (Kumar P, Rajasekaran K, Malarkannan S) Crit Rev Immunol 2024;44(1):55-77    
1Rapid and Deep Response to Lorlatinib in Pancreatic High-Grade Neuroendocrine Carcinoma With a Treatment Emergent Novel KANK1-ALK Fusion. (Dayyani F, Lee W, Houshyar R, Fontaine P) JCO Precis Oncol 2023 Jan;7:e2200230       3 Citations
1Expression of LIM domain-binding 3 (LDB3), a striated muscle Z-band alternatively spliced PDZ-motif protein in the nervous system. (Blech-Hermoni Y, Subedi K, Silver M, Jensen L, Coscia S, Kates MM, Zhao Y, Raley C, Edwards N, Tran B, Ray-Chaudhary A, Pathak P, Mankodi A) Sci Rep 2023 Jan 06;13(1):270       6 Citations
1Role of CD19 Chimeric Antigen Receptor T Cells in Second-Line Large B Cell Lymphoma: Lessons from Phase 3 Trials. An Expert Panel Opinion from the American Society for Transplantation and Cellular Therapy. (Perales MA, Anderson LD Jr, Jain T, Kenderian SS, Oluwole OO, Shah GL, Svoboda J, Hamadani M) Transplant Cell Ther 2022 Sep;28(9):546-559       30 Citations
1S-SCAM inhibits Axin-dependent synaptic function of GSK3β in a sex-dependent manner. (Kearney G, Grau D, Nieves Torres D, Shin SM, Lee SH) Sci Rep 2022 Mar 08;12(1):4090       2 Citations
2WDR26 and MTF2 are therapeutic targets in multiple myeloma. (Sun F, Cheng Y, Riordan JD, Dupuy A, Dubois W, Pisano M, Dong J, Mock B, Zhan F, Hari P, Janz S) J Hematol Oncol 2021 Dec 07;14(1):203       8 Citations
1Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome. (Chu H, Sacharidou A, Nguyen A, Li C, Chambliss KL, Salmon JE, Shen YM, Lo J, Leone GW, Herz J, Hui DY, Marciano DK, Abrahams VM, Natale BV, Montalbano AP, Xiao X, Xu L, Natale DR, Shaul PW, Mineo C) Circ Res 2021 Sep 17;129(7):735-750       16 Citations
2Correlates and Outcomes of Early Acute Kidney Injury after Hematopoietic Cell Transplantation. (Bhasin B, Ber Ce P, Szabo A, Chhabra S, D'Souza A) Am J Med Sci 2021 Jul;362(1):72-77       5 Citations
1PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2. (Murphy SA, Miyamoto M, Kervadec A, Kannan S, Tampakakis E, Kambhampati S, Lin BL, Paek S, Andersen P, Lee DI, Zhu R, An SS, Kass DA, Uosaki H, Colas AR, Kwon C) Nat Commun 2021 Mar 12;12(1):1648       68 Citations
1Targeting oncoproteins with a positive selection assay for protein degraders. (Koduri V, Duplaquet L, Lampson BL, Wang AC, Sabet AH, Ishoey M, Paulk J, Teng M, Harris IS, Endress JE, Liu X, Dasilva E, Paulo JA, Briggs KJ, Doench JG, Ott CJ, Zhang T, Donovan KA, Fischer ES, Gygi SP, Gray NS, Bradner J, Medin JA, Buhrlage SJ, Oser MG, Kaelin WG Jr) Sci Adv 2021 Feb;7(6)       37 Citations
2Café au lait spots: When and how to pursue their genetic origins. (Lalor L, Davies OMT, Basel D, Siegel DH) Clin Dermatol 2020;38(4):421-431       24 Citations
1A non-GPCR-binding partner interacts with a novel surface on β-arrestin1 to mediate GPCR signaling. (Zhuo Y, Gurevich VV, Vishnivetskiy SA, Klug CS, Marchese A) J Biol Chem 2020 Oct 09;295(41):14111-14124       14 Citations
1Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes. (Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin CM, Alontaga AY, McDaniel JM, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence HR, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha AM, Cleveland JL, Epling-Burnette PK) Blood 2020 Aug 13;136(7):857-870       17 Citations
1Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis. (Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I) Cell Metab 2020 May 05;31(5):969-986.e7       158 Citations
1Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12. (Arab JP, Cabrera D, Sehrawat TS, Jalan-Sakrikar N, Verma VK, Simonetto D, Cao S, Yaqoob U, Leon J, Freire M, Vargas JI, De Assuncao TM, Kwon JH, Guo Y, Kostallari E, Cai Q, Kisseleva T, Oh Y, Arrese M, Huebert RC, Shah VH) J Hepatol 2020 Jul;73(1):149-160       53 Citations
1Investigation of a dilated cardiomyopathy-associated variant in BAG3 using genome-edited iPSC-derived cardiomyocytes. (McDermott-Roe C, Lv W, Maximova T, Wada S, Bukowy J, Marquez M, Lai S, Shehu A, Benjamin I, Geurts A, Musunuru K) JCI Insight 2019 Nov 14;4(22)       37 Citations
2Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. (Mammoto T, Torisawa YS, Muyleart M, Hendee K, Anugwom C, Gutterman D, Mammoto A) Aging (Albany NY) 2019 Sep 05;11(17):7051-7069       31 Citations
2ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic β-cells. (Han EH, Singh P, Lee IK, Urrutia R, Chi YI) J Biol Chem 2019 Sep 20;294(38):13983-13994       10 Citations
2CTLA4 Message Reflects Pathway Disruption in Monogenic Disorders and Under Therapeutic Blockade. (Garcia-Perez JE, Baxter RM, Kong DS, Tobin R, McCarter M, Routes JM, Verbsky J, Jordan MB, Dutmer CM, Hsieh EWY) Front Immunol 2019;10:998       13 Citations
2The Roles of Hippo Signaling Transducers Yap and Taz in Chromatin Remodeling. (Hillmer RE, Link BA) Cells 2019 May 24;8(5)       52 Citations
1The bispecific antibody HB-32, blockade of both VEGF and DLL4 shows potent anti-angiogenic activity in vitro and anti-tumor activity in breast cancer xenograft models. (Zhou R, Wang S, Wen H, Wang M, Wu M) Exp Cell Res 2019 Jul 15;380(2):141-148       20 Citations
1Lessons learned from a lncRNA odyssey for two genes with vascular functions, DLL4 and TIE1. (Chowdhury TA, Li K, Ramchandran R) Vascul Pharmacol 2019 Mar;114:103-109       4 Citations
1Assessment of expression of RELN signaling pathway in multiple sclerosis patients. (Talebian S, Gharesouran J, Ghafouri-Fard S, Esfahani BS, Arsang-Jang S, Omrani MD, Taheri M, Rezazadeh M) Immunobiology 2019 May;224(3):402-407       7 Citations
1TRPV4 regulates matrix stiffness and TGFβ1-induced epithelial-mesenchymal transition. (Sharma S, Goswami R, Zhang DX, Rahaman SO) J Cell Mol Med 2019 Feb;23(2):761-774       94 Citations
2Endothelial YAP1 in Regenerative Lung Growth through the Angiopoietin-Tie2 Pathway. (Mammoto T, Muyleart M, Mammoto A) Am J Respir Cell Mol Biol 2019 Jan;60(1):117-127       32 Citations
1Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency. (Rak MA, Buehler J, Zeltzer S, Reitsma J, Molina B, Terhune S, Goodrum F) J Virol 2018 Oct 15;92(20)       40 Citations
1Temperature-sensitive sarcomeric protein post-translational modifications revealed by top-down proteomics. (Cai W, Hite ZL, Lyu B, Wu Z, Lin Z, Gregorich ZR, Messer AE, McIlwain SJ, Marston SB, Kohmoto T, Ge Y) J Mol Cell Cardiol 2018 Sep;122:11-22       18 Citations
1Expression Analysis of CYFIP1 and CAMKK2 Genes in the Blood of Epileptic and Schizophrenic Patients. (Sayad A, Ranjbaran F, Ghafouri-Fard S, Arsang-Jang S, Taheri M) J Mol Neurosci 2018 Jul;65(3):336-342       7 Citations
1Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension. (Cornelius RJ, Zhang C, Erspamer KJ, Agbor LN, Sigmund CD, Singer JD, Yang CL, Ellison DH) Am J Physiol Renal Physiol 2018 Oct 01;315(4):F1006-F1018       24 Citations
2YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α. (Mammoto A, Muyleart M, Kadlec A, Gutterman D, Mammoto T) Microvasc Res 2018 Sep;119:73-83       50 Citations
1Assessment of Protein Prenylation Pathway in Multiple Sclerosis Patients. (Taheri M, Ghafouri-Fard S, Sayad A, Arsang-Jang S, Mazdeh M, Toghi M, Omrani MD) J Mol Neurosci 2018 Apr;64(4):581-590       10 Citations
3Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. (Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH) JCI Insight 2017 Dec 21;2(24)       21 Citations
1MRAP2 regulates ghrelin receptor signaling and hunger sensing. (Srisai D, Yin TC, Lee AA, Rouault AAJ, Pearson NA, Grobe JL, Sebag JA) Nat Commun 2017 Sep 28;8(1):713       63 Citations
2The two novel DLL4-targeting antibody-drug conjugates MvM03 and MGD03 show potent anti-tumour activity in breast cancer xenograft models. (Wang S, Zhou R, Sun F, Li R, Wang M, Wu M) Cancer Lett 2017 Nov 28;409:125-136       12 Citations
1Platelets reduce anoikis and promote metastasis by activating YAP1 signaling. (Haemmerle M, Taylor ML, Gutschner T, Pradeep S, Cho MS, Sheng J, Lyons YM, Nagaraja AS, Dood RL, Wen Y, Mangala LS, Hansen JM, Rupaimoole R, Gharpure KM, Rodriguez-Aguayo C, Yim SY, Lee JS, Ivan C, Hu W, Lopez-Berestein G, Wong ST, Karlan BY, Levine DA, Liu J, Afshar-Kharghan V, Sood AK) Nat Commun 2017 Aug 21;8(1):310       224 Citations
7Host genetic modifiers of nonproductive angiogenesis inhibit breast cancer. (Flister MJ, Tsaih SW, Stoddard A, Plasterer C, Jagtap J, Parchur AK, Sharma G, Prisco AR, Lemke A, Murphy D, Al-Gizawiy M, Straza M, Ran S, Geurts AM, Dwinell MR, Greene AS, Bergom C, LaViolette PS, Joshi A) Breast Cancer Res Treat 2017 Aug;165(1):53-64       15 Citations
1Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro. (Schaefer A, van Duijn TJ, Majolee J, Burridge K, Hordijk PL) J Immunol 2017 Jun 15;198(12):4823-4836       16 Citations
1Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies. (Previs RA, Armaiz-Pena GN, Ivan C, Dalton HJ, Rupaimoole R, Hansen JM, Lyons Y, Huang J, Haemmerle M, Wagner MJ, Gharpure KM, Nagaraja AS, Filant J, McGuire MH, Noh K, Dorniak PL, Linesch SL, Mangala LS, Pradeep S, Wu SY, Sood AK) J Natl Cancer Inst 2017 Jul 01;109(7)       12 Citations
1Genome-wide association study of sepsis in extremely premature infants. (Srinivasan L, Page G, Kirpalani H, Murray JC, Das A, Higgins RD, Carlo WA, Bell EF, Goldberg RN, Schibler K, Sood BG, Stevenson DK, Stoll BJ, Van Meurs KP, Johnson KJ, Levy J, McDonald SA, Zaterka-Baxter KM, Kennedy KA, Sánchez PJ, Duara S, Walsh MC, Shankaran S, Wynn JL, Cotten CM, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network) Arch Dis Child Fetal Neonatal Ed 2017 Sep;102(5):F439-F445       29 Citations
1Proteomic Screen for Cellular Targets of the Vaccinia Virus F10 Protein Kinase Reveals that Phosphorylation of mDia Regulates Stress Fiber Formation. (Greseth MD, Carter DC, Terhune SS, Traktman P) Mol Cell Proteomics 2017 Apr;16(4 suppl 1):S124-S143       9 Citations
1Multimodal Imaging of Photoreceptor Structure in Choroideremia. (Sun LW, Johnson RD, Williams V, Summerfelt P, Dubra A, Weinberg DV, Stepien KE, Fishman GA, Carroll J) PLoS One 2016;11(12):e0167526       58 Citations
1β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4. (Alekhina O, Marchese A) J Biol Chem 2016 Dec 09;291(50):26083-26097       30 Citations
1Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. (Jagadish N, Gupta N, Agarwal S, Parashar D, Sharma A, Fatima R, Topno AP, Kumar V, Suri A) Tumour Biol 2016 Oct;37(10):13101-13110       20 Citations
1MICAL1 controls cell invasive phenotype via regulating oxidative stress in breast cancer cells. (Deng W, Wang Y, Gu L, Duan B, Cui J, Zhang Y, Chen Y, Sun S, Dong J, Du J) BMC Cancer 2016 Jul 18;16:489       56 Citations
1A humanized anti-DLL4 antibody promotes dysfunctional angiogenesis and inhibits breast tumor growth. (Jia X, Wang W, Xu Z, Wang S, Wang T, Wang M, Wu M) Sci Rep 2016 Jun 15;6:27985       26 Citations
1A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. (Goetz B, An W, Mohapatra B, Zutshi N, Iseka F, Storck MD, Meza J, Sheinin Y, Band V, Band H) Oncotarget 2016 Aug 09;7(32):51107-51123       11 Citations
1Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma. (Park YY, Sohn BH, Johnson RL, Kang MH, Kim SB, Shim JJ, Mangala LS, Kim JH, Yoo JE, Rodriguez-Aguayo C, Pradeep S, Hwang JE, Jang HJ, Lee HS, Rupaimoole R, Lopez-Berestein G, Jeong W, Park IS, Park YN, Sood AK, Mills GB, Lee JS) Hepatology 2016 Jan;63(1):159-72       128 Citations
2Retinal Architecture in ​RGS9- and ​R9AP-Associated Retinal Dysfunction (Bradyopsia). (Strauss RW, Dubis AM, Cooper RF, Ba-Abbad R, Moore AT, Webster AR, Dubra A, Carroll J, Michaelides M) Am J Ophthalmol 2015 Dec;160(6):1269-1275.e1       17 Citations
1MicroRNA-224 promotes tumor progression in nonsmall cell lung cancer. (Cui R, Meng W, Sun HL, Kim T, Ye Z, Fassan M, Jeon YJ, Li B, Vicentini C, Peng Y, Lee TJ, Luo Z, Liu L, Xu D, Tili E, Jin V, Middleton J, Chakravarti A, Lautenschlaeger T, Croce CM) Proc Natl Acad Sci U S A 2015 Aug 04;112(31):E4288-97       140 Citations
1Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project. (Auer PL, Nalls M, Meschia JF, Worrall BB, Longstreth WT Jr, Seshadri S, Kooperberg C, Burger KM, Carlson CS, Carty CL, Chen WM, Cupples LA, DeStefano AL, Fornage M, Hardy J, Hsu L, Jackson RD, Jarvik GP, Kim DS, Lakshminarayan K, Lange LA, Manichaikul A, Quinlan AR, Singleton AB, Thornton TA, Nickerson DA, Peters U, Rich SS, National Heart, Lung, and Blood Institute Exome Sequencing Project) JAMA Neurol 2015 Jul;72(7):781-8       53 Citations
1Novel PSTPIP1 gene mutation in a patient with pyogenic arthritis, pyoderma gangrenosum and acne (PAPA) syndrome. (Lindwall E, Singla S, Davis WE, Quinet RJ) Semin Arthritis Rheum 2015 Aug;45(1):91-3       46 Citations
1FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets. (Begonja AJ, Pluthero FG, Suphamungmee W, Giannini S, Christensen H, Leung R, Lo RW, Nakamura F, Lehman W, Plomann M, Hoffmeister KM, Kahr WH, Hartwig JH, Falet H) Blood 2015 Jul 02;126(1):80-8       52 Citations
1Mutation of SH2B3 (LNK), a genome-wide association study candidate for hypertension, attenuates Dahl salt-sensitive hypertension via inflammatory modulation. (Rudemiller NP, Lund H, Priestley JR, Endres BT, Prokop JW, Jacob HJ, Geurts AM, Cohen EP, Mattson DL) Hypertension 2015 May;65(5):1111-7       59 Citations
2YAP is essential for tissue tension to ensure vertebrate 3D body shape. (Porazinski S, Wang H, Asaoka Y, Behrndt M, Miyamoto T, Morita H, Hata S, Sasaki T, Krens SFG, Osada Y, Asaka S, Momoi A, Linton S, Miesfeld JB, Link BA, Senga T, Shimizu N, Nagase H, Matsuura S, Bagby S, Kondoh H, Nishina H, Heisenberg CP, Furutani-Seiki M) Nature 2015 May 14;521(7551):217-221       200 Citations
3BAG3 myofibrillar myopathy presenting with cardiomyopathy. (Konersman CG, Bordini BJ, Scharer G, Lawlor MW, Zangwill S, Southern JF, Amos L, Geddes GC, Kliegman R, Collins MP) Neuromuscul Disord 2015 May;25(5):418-22       68 Citations
3S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. (Zhang N, Zhong P, Shin SM, Metallo J, Danielson E, Olsen CM, Liu QS, Lee SH) J Neurosci 2015 Feb 04;35(5):1892-904       19 Citations
3SH2B3 Is a Genetic Determinant of Cardiac Inflammation and Fibrosis. (Flister MJ, Hoffman MJ, Lemke A, Prisco SZ, Rudemiller N, O'Meara CC, Tsaih SW, Moreno C, Geurts AM, Lazar J, Adhikari N, Hall JL, Jacob HJ) Circ Cardiovasc Genet 2015 Apr;8(2):294-304       27 Citations
1Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. (Coffee and Caffeine Genetics Consortium, Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, Teumer A, Yu K, Marques-Vidal P, Rawal R, Manichaikul A, Wojczynski MK, Vink JM, Zhao JH, Burlutsky G, Lahti J, Mikkilä V, Lemaitre RN, Eriksson J, Musani SK, Tanaka T, Geller F, Luan J, Hui J, Mägi R, Dimitriou M, Garcia ME, Ho WK, Wright MJ, Rose LM, Magnusson PK, Pedersen NL, Couper D, Oostra BA, Hofman A, Ikram MA, Tiemeier HW, Uitterlinden AG, van Rooij FJ, Barroso I, Johansson I, Xue L, Kaakinen M, Milani L, Power C, Snieder H, Stolk RP, Baumeister SE, Biffar R, Gu F, Bastardot F, Kutalik Z, Jacobs DR Jr, Forouhi NG, Mihailov E, Lind L, Lindgren C, Michaëlsson K, Morris A, Jensen M, Khaw KT, Luben RN, Wang JJ, Männistö S, Perälä MM, Kähönen M, Lehtimäki T, Viikari J, Mozaffarian D, Mukamal K, Psaty BM, Döring A, Heath AC, Montgomery GW, Dahmen N, Carithers T, Tucker KL, Ferrucci L, Boyd HA, Melbye M, Treur JL, Mellström D, Hottenga JJ, Prokopenko I, Tönjes A, Deloukas P, Kanoni S, Lorentzon M, Houston DK, Liu Y, Danesh J, Rasheed A, Mason MA, Zonderman AB, Franke L, Kristal BS, International Parkinson’s Disease Genomics Consortium (IPDGC), North American Brain Expression Consortium (NABEC), UK Brain Expression Consortium (UKBEC), Karjalainen J, Reed DR, Westra HJ, Evans MK, Saleheen D, Harris TB, Dedoussis G, Curhan G, Stumvoll M, Beilby J, Pasquale LR, Feenstra B, Bandinelli S, Ordovas JM, Chan AT, Peters U, Ohlsson C, Gieger C, Martin NG, Waldenberger M, Siscovick DS, Raitakari O, Eriksson JG, Mitchell P, Hunter DJ, Kraft P, Rimm EB, Boomsma DI, Borecki IB, Loos RJ, Wareham NJ, Vollenweider P, Caporaso N, Grabe HJ, Neuhouser ML, Wolffenbuttel BH, Hu FB, Hyppönen E, Järvelin MR, Cupples LA, Franks PW, Ridker PM, van Duijn CM, Heiss G, Metspalu A, North KE, Ingelsson E, Nettleton JA, van Dam RM, Chasman DI) Mol Psychiatry 2015 May;20(5):647-656       226 Citations
1Mutations in IFT172 cause isolated retinal degeneration and Bardet-Biedl syndrome. (Bujakowska KM, Zhang Q, Siemiatkowska AM, Liu Q, Place E, Falk MJ, Consugar M, Lancelot ME, Antonio A, Lonjou C, Carpentier W, Mohand-Saïd S, den Hollander AI, Cremers FP, Leroy BP, Gai X, Sahel JA, van den Born LI, Collin RW, Zeitz C, Audo I, Pierce EA) Hum Mol Genet 2015 Jan 01;24(1):230-42       135 Citations
1Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels. (Kim JH, Hong SK, Wu PK, Richards AL, Jackson WT, Park JI) Exp Cell Res 2014 Oct 01;327(2):340-52       107 Citations
2Deleted in Breast Cancer 1 regulates cellular senescence during obesity. (Escande C, Nin V, Pirtskhalava T, Chini CC, Thereza Barbosa M, Mathison A, Urrutia R, Tchkonia T, Kirkland JL, Chini EN) Aging Cell 2014 Oct;13(5):951-3       30 Citations
1The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4. (Holleman J, Marchese A) Mol Biol Cell 2014 Jun 15;25(12):1892-904       44 Citations
1Expression profiling of the RPE in zebrafish smarca4 mutant revealed altered signals that potentially affect RPE and retinal differentiation. (Zhang L, Ma P, Collery R, Trowbridge S, Zhang M, Zhong W, Leung YF) Mol Vis 2014;20:56-72       5 Citations
1The adaptor CARD9 is required for adaptive but not innate immunity to oral mucosal Candida albicans infections. (Bishu S, Hernández-Santos N, Simpson-Abelson MR, Huppler AR, Conti HR, Ghilardi N, Mamo AJ, Gaffen SL) Infect Immun 2014 Mar;82(3):1173-80       57 Citations
1Sperm associated antigen 9 plays an important role in bladder transitional cell carcinoma. (Kanojia D, Garg M, Saini S, Agarwal S, Parashar D, Jagadish N, Seth A, Bhatnagar A, Gupta A, Kumar R, Lohiya NK, Suri A) PLoS One 2013;8(12):e81348       35 Citations
1Down regulation of SPAG9 reduces growth and invasive potential of triple-negative breast cancer cells: possible implications in targeted therapy. (Sinha A, Agarwal S, Parashar D, Verma A, Saini S, Jagadish N, Ansari AS, Lohiya NK, Suri A) J Exp Clin Cancer Res 2013 Sep 19;32(1):69       42 Citations
1Aggregate-prone R120GCRYAB triggers multifaceted modifications of the thioredoxin system. (Banerjee Mustafi S, Grose JH, Zhang H, Pratt GW, Sadoshima J, Christians ES, Benjamin IJ) Antioxid Redox Signal 2014 Jun 20;20(18):2891-906       9 Citations
1Autophagy sensitivity of neuroendocrine lung tumor cells. (Hong SK, Kim JH, Starenki D, Park JI) Int J Oncol 2013 Dec;43(6):2031-8       12 Citations
1Signaling by Fyn-ADAP via the Carma1-Bcl-10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells. (Rajasekaran K, Kumar P, Schuldt KM, Peterson EJ, Vanhaesebroeck B, Dixit V, Thakar MS, Malarkannan S) Nat Immunol 2013 Nov;14(11):1127-36       79 Citations
1Recessive truncating titin gene, TTN, mutations presenting as centronuclear myopathy. (Ceyhan-Birsoy O, Agrawal PB, Hidalgo C, Schmitz-Abe K, DeChene ET, Swanson LC, Soemedi R, Vasli N, Iannaccone ST, Shieh PB, Shur N, Dennison JM, Lawlor MW, Laporte J, Markianos K, Fairbrother WG, Granzier H, Beggs AH) Neurology 2013 Oct 01;81(14):1205-14       186 Citations
1Overexpression of microRNA-1 promotes cardiomyocyte commitment from human cardiovascular progenitors via suppressing WNT and FGF signaling pathways. (Lu TY, Lin B, Li Y, Arora A, Han L, Cui C, Coronnello C, Sheng Y, Benos PV, Yang L) J Mol Cell Cardiol 2013 Oct;63:146-54       63 Citations
1Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo. (Tolmachova T, Tolmachov OE, Barnard AR, de Silva SR, Lipinski DM, Walker NJ, Maclaren RE, Seabra MC) J Mol Med (Berl) 2013 Jul;91(7):825-37       83 Citations
1Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation. (Tanaka S, Fukumoto Y, Nochioka K, Minami T, Kudo S, Shiba N, Takai Y, Williams CL, Liao JK, Shimokawa H) Arterioscler Thromb Vasc Biol 2013 Jul;33(7):1591-600       79 Citations
1Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding. (Bigley TM, Reitsma JM, Mirza SP, Terhune SS) J Virol 2013 Jul;87(13):7393-408       32 Citations
1Diagnostic and therapeutic advances in blastic plasmacytoid dendritic cell neoplasm: a focus on hematopoietic cell transplantation. (Kharfan-Dabaja MA, Lazarus HM, Nishihori T, Mahfouz RA, Hamadani M) Biol Blood Marrow Transplant 2013 Jul;19(7):1006-12       75 Citations
1High-resolution images of retinal structure in patients with choroideremia. (Syed R, Sundquist SM, Ratnam K, Zayit-Soudry S, Zhang Y, Crawford JB, MacDonald IM, Godara P, Rha J, Carroll J, Roorda A, Stepien KE, Duncan JL) Invest Ophthalmol Vis Sci 2013 Feb 01;54(2):950-61       92 Citations
2Association of Piebaldism, multiple café-au-lait macules, and intertriginous freckling: clinical evidence of a common pathway between KIT and sprouty-related, ena/vasodilator-stimulated phosphoprotein homology-1 domain containing protein 1 (SPRED1). (Chiu YE, Dugan S, Basel D, Siegel DH) Pediatr Dermatol 2013;30(3):379-82       23 Citations
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1Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains. (Yuan R, Meng Q, Nautiyal J, Flurkey K, Tsaih SW, Krier R, Parker MG, Harrison DE, Paigen B) Proc Natl Acad Sci U S A 2012 May 22;109(21):8224-9       96 Citations
1Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling. (Malik R, Soh UJ, Trejo J, Marchese A) J Biol Chem 2012 Mar 16;287(12):9013-27       43 Citations
1Plasma DNA methylation of Wnt antagonists predicts recurrence of esophageal squamous cell carcinoma. (Liu JB, Qiang FL, Dong J, Cai J, Zhou SH, Shi MX, Chen KP, Hu ZB) World J Gastroenterol 2011 Nov 28;17(44):4917-21       52 Citations
1Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission. (Milosevic I, Giovedi S, Lou X, Raimondi A, Collesi C, Shen H, Paradise S, O'Toole E, Ferguson S, Cremona O, De Camilli P) Neuron 2011 Nov 17;72(4):587-601       279 Citations
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1CrkII associates with BCAR3 in response to endothelin-1 in human glomerular mesangial cells. (Rufanova VA, Sorokin A) Exp Biol Med (Maywood) 2006 Jun;231(6):752-6       6 Citations
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1Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family history. (Buttin BM, Powell MA, Mutch DG, Babb SA, Huettner PC, Edmonston TB, Herzog TJ, Rader JS, Gibb RK, Whelan AJ, Goodfellow PJ) Am J Hum Genet 2004 Jun;74(6):1262-9       59 Citations
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1Rapamycin antagonizes cyclosporin A- and tacrolimus (FK506)-mediated augmentation of linker for activation of T cell expression in T cells. (Cho CS, Chang Z, Elkahwaji J, Scheunemann TL, Manthei ER, Colburn M, Knechtle SJ, Hamawy MM) Int Immunol 2003 Nov;15(11):1369-78       11 Citations
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1Formation of the yeast F1F0-ATP synthase dimeric complex does not require the ATPase inhibitor protein, Inh1. (Dienhart M, Pfeiffer K, Schagger H, Stuart RA) J Biol Chem 2002 Oct 18;277(42):39289-95       55 Citations
1MSI in endometrial carcinoma: absence of MLH1 promoter methylation is associated with increased familial risk for cancers. (Whelan AJ, Babb S, Mutch DG, Rader J, Herzog TJ, Todd C, Ivanovich JL, Goodfellow PJ) Int J Cancer 2002 Jun 10;99(5):697-704       36 Citations
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