Medical College of Wisconsin
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Publications indexed to the term Gene Knockdown Techniques

FacultyTitle
1Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA. (Juang LJ, Hur WS, Silva LM, Strilchuk AW, Francisco B, Leung J, Robertson MK, Groeneveld DJ, La Prairie B, Chun EM, Cap AP, Luyendyk JP, Palumbo JS, Cullis PR, Bugge TH, Flick MJ, Kastrup CJ) Blood 2022 Mar 03;139(9):1302-1311       27 Citations
1Generation of 'designer erythroblasts' lacking one or more blood group systems from CRISPR/Cas9 gene-edited human-induced pluripotent stem cells. (Pandey P, Zhang N, Curtis BR, Newman PJ, Denomme GA) J Cell Mol Med 2021 Oct;25(19):9340-9349       12 Citations
2Cardiomyocyte-produced miR-339-5p mediates pathology in Duchenne muscular dystrophy cardiomyopathy. (Gartz M, Beatka M, Prom MJ, Strande JL, Lawlor MW) Hum Mol Genet 2021 Nov 16;30(23):2347-2361       16 Citations
2Mortality and ventilatory effects of central serotonin deficiency during postnatal development depend on age but not sex. (Mouradian GC Jr, Kilby M, Alvarez S, Kaplan K, Hodges MR) Physiol Rep 2021 Jul;9(13):e14946       3 Citations
1Essential requirement for JPT2 in NAADP-evoked Ca2+ signaling. (Gunaratne GS, Brailoiu E, He S, Unterwald EM, Patel S, Slama JT, Walseth TF, Marchant JS) Sci Signal 2021 Mar 23;14(675)       92 Citations
1Mortalin depletion induces MEK/ERK-dependent and ANT/CypD-mediated death in vemurafenib-resistant B-RafV600E melanoma cells. (Wu PK, Hong SK, Park JI) Cancer Lett 2021 Apr 01;502:25-33       22 Citations
1Follicular Lymphoma-associated BTK Mutations are Inactivating Resulting in Augmented AKT Activation. (Hu N, Wang F, Sun T, Xu Z, Zhang J, Bernard D, Xu S, Wang S, Kaminski M, Devata S, Phillips T, Malek SN) Clin Cancer Res 2021 Apr 15;27(8):2301-2313       21 Citations
2NOGOB receptor-mediated RAS signaling pathway is a target for suppressing proliferating hemangioma. (Hu W, Liu Z, Salato V, North PE, Bischoff J, Kumar SN, Fang Z, Rajan S, Hussain MM, Miao QR) JCI Insight 2021 Feb 08;6(3)       17 Citations
7Peritoneal Spread of Ovarian Cancer Harbors Therapeutic Vulnerabilities Regulated by FOXM1 and EGFR/ERBB2 Signaling. (Parashar D, Nair B, Geethadevi A, George J, Nair A, Tsaih SW, Kadamberi IP, Gopinadhan Nair GK, Lu Y, Ramchandran R, Uyar DS, Rader JS, Ram PT, Mills GB, Pradeep S, Chaluvally-Raghavan P) Cancer Res 2020 Dec 15;80(24):5554-5568       39 Citations
1β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4. (D'Agostino G, Artinger M, Locati M, Perez L, Legler DF, Bianchi ME, Rüegg C, Thelen M, Marchese A, Rocchi MBL, Cecchinato V, Uguccioni M) Front Immunol 2020;11:550824       32 Citations
1Epigenomic Evaluation of Cholangiocyte Transforming Growth Factor-β Signaling Identifies a Selective Role for Histone 3 Lysine 9 Acetylation in Biliary Fibrosis. (Aseem SO, Jalan-Sakrikar N, Chi C, Navarro-Corcuera A, De Assuncao TM, Hamdan FH, Chowdhury S, Banales JM, Johnsen SA, Shah VH, Huebert RC) Gastroenterology 2021 Feb;160(3):889-905.e10       52 Citations
1Sustained depletion of FXIII-A by inducing acquired FXIII-B deficiency. (Strilchuk AW, Meixner SC, Leung J, Safikhan NS, Kulkarni JA, Russell HM, van der Meel R, Sutherland MR, Owens AP, Palumbo JS, Conway EM, Pryzdial ELG, Cullis PR, Kastrup CJ) Blood 2020 Dec 17;136(25):2946-2954       30 Citations
1Endogenous miR-204 Protects the Kidney against Chronic Injury in Hypertension and Diabetes. (Cheng Y, Wang D, Wang F, Liu J, Huang B, Baker MA, Yin J, Wu R, Liu X, Regner KR, Usa K, Liu Y, Zhang C, Dong L, Geurts AM, Wang N, Miller SS, He Y, Liang M) J Am Soc Nephrol 2020 Jul;31(7):1539-1554       86 Citations
1Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia. (Dou L, Yan F, Pang J, Zheng D, Li D, Gao L, Wang L, Xu Y, Shi J, Wang Q, Zhou L, Shen N, Singh P, Wang L, Li Y, Gao Y, Liu T, Chen C, Al-Kali A, Litzow MR, Chi YI, Bode AM, Liu C, Huang H, Liu D, Marcucci G, Liu S, Yu L) Nat Commun 2019 Nov 07;10(1):5051       23 Citations
1TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells. (Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A) Nat Commun 2019 May 02;10(1):2024       23 Citations
2LRP5 in age-related changes in vascular and alveolar morphogenesis in the lung. (Mammoto A, Muyleart M, Mammoto T) Aging (Albany NY) 2019 Jan 05;11(1):89-103       15 Citations
1PRKRA/PACT Expression Promotes Chemoresistance of Mucinous Ovarian Cancer. (Hisamatsu T, McGuire M, Wu SY, Rupaimoole R, Pradeep S, Bayraktar E, Noh K, Hu W, Hansen JM, Lyons Y, Gharpure KM, Nagaraja AS, Mangala LS, Mitamura T, Rodriguez-Aguayo C, Eun YG, Rose J, Bartholomeusz G, Ivan C, Lee JS, Matsuo K, Frumovitz M, Wong KK, Lopez-Berestein G, Sood AK) Mol Cancer Ther 2019 Jan;18(1):162-172       29 Citations
1NAADP-dependent Ca2+ signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system. (Gunaratne GS, Yang Y, Li F, Walseth TF, Marchant JS) Cell Calcium 2018 Nov;75:30-41       103 Citations
3Neuropathic pain in a Fabry disease rat model. (Miller JJ, Aoki K, Moehring F, Murphy CA, O'Hara CL, Tiemeyer M, Stucky CL, Dahms NM) JCI Insight 2018 Mar 22;3(6)       60 Citations
1PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. (De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R) Proc Natl Acad Sci U S A 2018 Jan 30;115(5):E982-E991       66 Citations
2Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. (Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, Lomberk G, Gao Y, Ligresti G, Tschumperlin DJ, Revzin A, Cao S, Shah VH) JCI Insight 2017 Dec 21;2(24)       22 Citations
1HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress. (Zhong P, Vickstrom CR, Liu X, Hu Y, Yu L, Yu HG, Liu QS) Elife 2018 Jan 02;7       79 Citations
1Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation. (Wu Y, Wang Y, Lin Y, Liu Y, Wang Y, Jia J, Singh P, Chi YI, Wang C, Dong C, Li W, Tao M, Napier D, Shi Q, Deng J, Evers BM, Zhou BP) Nat Commun 2017 Feb 15;8:14228       126 Citations
1The Nogo-B receptor promotes Ras plasma membrane localization and activation. (Zhao B, Hu W, Kumar S, Gonyo P, Rana U, Liu Z, Wang B, Duong WQ, Yang Z, Williams CL, Miao QR) Oncogene 2017 Jun 15;36(24):3406-3416       32 Citations
1Dynamin-related protein 1 mediates low glucose-induced endothelial dysfunction in human arterioles. (Tanner MJ, Wang J, Ying R, Suboc TB, Malik M, Couillard A, Branum A, Puppala V, Widlansky ME) Am J Physiol Heart Circ Physiol 2017 Mar 01;312(3):H515-H527       27 Citations
1Enhanced aggressiveness of bystander cells in an anti-tumor photodynamic therapy model: Role of nitric oxide produced by targeted cells. (Bazak J, Fahey JM, Wawak K, Korytowski W, Girotti AW) Free Radic Biol Med 2017 Jan;102:111-121       45 Citations
2Role of Twist1 Phosphorylation in Angiogenesis and Pulmonary Fibrosis. (Mammoto T, Jiang A, Jiang E, Mammoto A) Am J Respir Cell Mol Biol 2016 Nov;55(5):633-644       43 Citations
1A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis. (Xu S, Liu B, Yin M, Koroleva M, Mastrangelo M, Ture S, Morrell CN, Zhang DX, Fisher EA, Jin ZG) Oncotarget 2016 Jun 21;7(25):37622-37635       65 Citations
1Transcriptional Regulation of Brain-derived Neurotrophic Factor Coding Exon IX: ROLE OF NUCLEAR RESPIRATORY FACTOR 2. (Nair B, Wong-Riley MT) J Biol Chem 2016 Oct 21;291(43):22583-22593       21 Citations
1Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. (Illendula A, Gilmour J, Grembecka J, Tirumala VSS, Boulton A, Kuntimaddi A, Schmidt C, Wang L, Pulikkan JA, Zong H, Parlak M, Kuscu C, Pickin A, Zhou Y, Gao Y, Mishra L, Adli M, Castilla LH, Rajewski RA, Janes KA, Guzman ML, Bonifer C, Bushweller JH) EBioMedicine 2016 Jun;8:117-131       85 Citations
2Monosialoganglioside-Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins. (Franco DA, Truran S, Weissig V, Guzman-Villanueva D, Karamanova N, Senapati S, Burciu C, Ramirez-Alvarado M, Blancas-Mejia LM, Lindsay S, Hari P, Migrino RQ) J Am Heart Assoc 2016 Jun 13;5(6)       11 Citations
1Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation. (Chugh S, Meza J, Sheinin YM, Ponnusamy MP, Batra SK) Br J Cancer 2016 Jun 14;114(12):1376-86       49 Citations
2Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer. (Chaluvally-Raghavan P, Jeong KJ, Pradeep S, Silva AM, Yu S, Liu W, Moss T, Rodriguez-Aguayo C, Zhang D, Ram P, Liu J, Lu Y, Lopez-Berestein G, Calin GA, Sood AK, Mills GB) Cell Rep 2016 May 17;15(7):1493-1504       87 Citations
2Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes. (Zappia KJ, Garrison SR, Palygin O, Weyer AD, Barabas ME, Lawlor MW, Staruschenko A, Stucky CL) PLoS One 2016;11(3):e0151602       25 Citations
2Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice. (McMurray KM, Sidhu PS, Cook JM, Arnold LA, Palmer AA) Addict Biol 2017 Mar;22(2):381-389       11 Citations
3Nogo-B Receptor Modulates Pulmonary Artery Smooth Muscle Cell Function in Developing Lungs. (Tadokoro KS, Rana U, Jing X, Konduri GG, Miao QR, Teng RJ) Am J Respir Cell Mol Biol 2016 Jun;54(6):892-900       13 Citations
1AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer. (Hong D, Kurzrock R, Kim Y, Woessner R, Younes A, Nemunaitis J, Fowler N, Zhou T, Schmidt J, Jo M, Lee SJ, Yamashita M, Hughes SG, Fayad L, Piha-Paul S, Nadella MV, Mohseni M, Lawson D, Reimer C, Blakey DC, Xiao X, Hsu J, Revenko A, Monia BP, MacLeod AR) Sci Transl Med 2015 Nov 18;7(314):314ra185       415 Citations
1The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. (Pai P, Rachagani S, Lakshmanan I, Macha MA, Sheinin Y, Smith LM, Ponnusamy MP, Batra SK) Mol Oncol 2016 Feb;10(2):224-39       34 Citations
1Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas. (Arora S, Yan H, Cho I, Fan HY, Luo B, Gai X, Bodian DL, Vockley JG, Zhou Y, Handorf EA, Egleston BL, Andrake MD, Nicolas E, Serebriiskii IG, Yen TJ, Hall MJ, Golemis EA, Enders GH) Gastroenterology 2015 Dec;149(7):1872-1883.e9       31 Citations
1Regulating anxiety with extrasynaptic inhibition. (Botta P, Demmou L, Kasugai Y, Markovic M, Xu C, Fadok JP, Lu T, Poe MM, Xu L, Cook JM, Rudolph U, Sah P, Ferraguti F, Lüthi A) Nat Neurosci 2015 Oct;18(10):1493-500       153 Citations
1Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics. (Xiao L, Xian H, Lee KY, Xiao B, Wang H, Yu F, Shen HM, Liou YC) J Biol Chem 2015 Oct 09;290(41):24961-74       36 Citations
1Targeting c-MYC in Platinum-Resistant Ovarian Cancer. (Reyes-González JM, Armaiz-Peña GN, Mangala LS, Valiyeva F, Ivan C, Pradeep S, Echevarría-Vargas IM, Rivera-Reyes A, Sood AK, Vivas-Mejía PE) Mol Cancer Ther 2015 Oct;14(10):2260-9       116 Citations
1Antithrombin III/SerpinC1 insufficiency exacerbates renal ischemia/reperfusion injury. (Wang F, Zhang G, Lu Z, Geurts AM, Usa K, Jacob HJ, Cowley AW, Wang N, Liang M) Kidney Int 2015 Oct;88(4):796-803       68 Citations
1MASH1/Ascl1a leads to GAP43 expression and axon regeneration in the adult CNS. (Williams RR, Venkatesh I, Pearse DD, Udvadia AJ, Bunge MB) PLoS One 2015;10(3):e0118918       42 Citations
3Altered prostanoid metabolism contributes to impaired angiogenesis in persistent pulmonary hypertension in a fetal lamb model. (Mahajan CN, Afolayan AJ, Eis A, Teng RJ, Konduri GG) Pediatr Res 2015 Mar;77(3):455-62       23 Citations
3Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice. (Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ) BMC Genet 2014 Dec 05;15:135       19 Citations
1Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics. (Paulus JD, Link BA) PLoS One 2014;9(10):e109922       22 Citations
1Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase. (Fu X, Creighton CJ, Biswal NC, Kumar V, Shea M, Herrera S, Contreras A, Gutierrez C, Wang T, Nanda S, Giuliano M, Morrison G, Nardone A, Karlin KL, Westbrook TF, Heiser LM, Anur P, Spellman P, Guichard SM, Smith PD, Davies BR, Klinowska T, Lee AV, Mills GB, Rimawi MF, Hilsenbeck SG, Gray JW, Joshi A, Osborne CK, Schiff R) Breast Cancer Res 2014 Sep 11;16(5):430       72 Citations
1Transcriptional inhibition of etv2 expression is essential for embryonic cardiac development. (Schupp MO, Waas M, Chun CZ, Ramchandran R) Dev Biol 2014 Sep 01;393(1):71-83       15 Citations
1Notch3 pathway alterations in ovarian cancer. (Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK) Cancer Res 2014 Jun 15;74(12):3282-93       66 Citations
1Activation of α2A-containing nicotinic acetylcholine receptors mediates nicotine-induced motor output in embryonic zebrafish. (Menelaou E, Udvadia AJ, Tanguay RL, Svoboda KR) Eur J Neurosci 2014 Jul;40(1):2225-40       16 Citations
1Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication. (Kapoor A, Forman M, Arav-Boger R) PLoS One 2014;9(3):e92704       49 Citations
1Direct crosstalk between cancer and osteoblast lineage cells fuels metastatic growth in bone via auto-amplification of IL-6 and RANKL signaling pathways. (Zheng Y, Chow SO, Boernert K, Basel D, Mikuscheva A, Kim S, Fong-Yee C, Trivedi T, Buttgereit F, Sutherland RL, Dunstan CR, Zhou H, Seibel MJ) J Bone Miner Res 2014 Sep;29(9):1938-49       44 Citations
1CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer. (Colbert LE, Petrova AV, Fisher SB, Pantazides BG, Madden MZ, Hardy CW, Warren MD, Pan Y, Nagaraju GP, Liu EA, Saka B, Hall WA, Shelton JW, Gandhi K, Pauly R, Kowalski J, Kooby DA, El-Rayes BF, Staley CA 3rd, Adsay NV, Curran WJ Jr, Landry JC, Maithel SK, Yu DS) Cancer Res 2014 May 15;74(10):2677-87       36 Citations
1Regulation of ferroptotic cancer cell death by GPX4. (Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, Stockwell BR) Cell 2014 Jan 16;156(1-2):317-331       6620 Citations
1Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice. (Muir AM, Ren Y, Butz DH, Davis NA, Blank RD, Birk DE, Lee SJ, Rowe D, Feng JQ, Greenspan DS) Hum Mol Genet 2014 Jun 15;23(12):3085-101       65 Citations
1SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1. (Zhou X, Fan LX, Li K, Ramchandran R, Calvet JP, Li X) Hum Mol Genet 2014 Mar 15;23(6):1644-55       47 Citations
1NOTCH3 is a prognostic factor that promotes glioma cell proliferation, migration and invasion via activation of CCND1 and EGFR. (Alqudah MA, Agarwal S, Al-Keilani MS, Sibenaller ZA, Ryken TC, Assem M) PLoS One 2013;8(10):e77299       51 Citations
1Skin-derived cues control arborization of sensory dendrites in Caenorhabditis elegans. (Salzberg Y, Díaz-Balzac CA, Ramirez-Suarez NJ, Attreed M, Tecle E, Desbois M, Kaprielian Z, Bülow HE) Cell 2013 Oct 10;155(2):308-20       130 Citations
1Neuron-specific specificity protein 4 bigenomically regulates the transcription of all mitochondria- and nucleus-encoded cytochrome c oxidase subunit genes in neurons. (Johar K, Priya A, Dhar S, Liu Q, Wong-Riley MT) J Neurochem 2013 Nov;127(4):496-508       26 Citations
1A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation. (Boccuto L, Aoki K, Flanagan-Steet H, Chen CF, Fan X, Bartel F, Petukh M, Pittman A, Saul R, Chaubey A, Alexov E, Tiemeyer M, Steet R, Schwartz CE) Hum Mol Genet 2014 Jan 15;23(2):418-33       158 Citations
2Twist1 controls lung vascular permeability and endotoxin-induced pulmonary edema by altering Tie2 expression. (Mammoto T, Jiang E, Jiang A, Lu Y, Juan AM, Chen J, Mammoto A) PLoS One 2013;8(9):e73407       31 Citations
1Gene silencing of A-kinase anchor protein 4 inhibits cervical cancer growth in vitro and in vivo. (Saini S, Agarwal S, Sinha A, Verma A, Parashar D, Gupta N, Ansari AS, Lohiya NK, Jagadish N, Suri A) Cancer Gene Ther 2013 Jul;20(7):413-20       22 Citations
1LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. (Fogeron ML, Müller H, Schade S, Dreher F, Lehmann V, Kühnel A, Scholz AK, Kashofer K, Zerck A, Fauler B, Lurz R, Herwig R, Zatloukal K, Lehrach H, Gobom J, Nordhoff E, Lange BM) Nat Commun 2013;4:1531       63 Citations
1RAS/MEK-independent gene expression reveals BMP2-related malignant phenotypes in the Nf1-deficient MPNST. (Sun D, Haddad R, Kraniak JM, Horne SD, Tainsky MA) Mol Cancer Res 2013 Jun;11(6):616-27       13 Citations
1Macrophage migration inhibitory factor in head and neck squamous cell carcinoma: clinical and experimental studies. (Kindt N, Preillon J, Kaltner H, Gabius HJ, Chevalier D, Rodriguez A, Johnson BD, Megalizzi V, Decaestecker C, Laurent G, Saussez S) J Cancer Res Clin Oncol 2013 May;139(5):727-37       38 Citations
1LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation. (Menden H, Tate E, Hogg N, Sampath V) Am J Physiol Lung Cell Mol Physiol 2013 Mar 15;304(6):L445-55       61 Citations
1Integrin α5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish. (Hayes JM, Hartsock A, Clark BS, Napier HR, Link BA, Gross JM) Mol Biol Cell 2012 Dec;23(24):4725-38       36 Citations
1Modulation of function of sodium-dependent vitamin C transporter 1 (SVCT1) by Rab8a in intestinal epithelial cells: studies utilizing Caco-2 cells and Rab8a knockout mice. (Subramanian VS, Subramanya SB, Ghosal A, Marchant JS, Harada A, Said HM) Dig Dis Sci 2013 Mar;58(3):641-9       10 Citations
1Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance. (Balko JM, Cook RS, Vaught DB, Kuba MG, Miller TW, Bhola NE, Sanders ME, Granja-Ingram NM, Smith JJ, Meszoely IM, Salter J, Dowsett M, Stemke-Hale K, González-Angulo AM, Mills GB, Pinto JA, Gómez HL, Arteaga CL) Nat Med 2012 Jul;18(7):1052-9       232 Citations
2S-SCAM/MAGI-2 is an essential synaptic scaffolding molecule for the GluA2-containing maintenance pool of AMPA receptors. (Danielson E, Zhang N, Metallo J, Kaleka K, Shin SM, Gerges N, Lee SH) J Neurosci 2012 May 16;32(20):6967-80       46 Citations
1Gene trapping uncovers sex-specific mechanisms for upstream stimulatory factors 1 and 2 in angiotensinogen expression. (Park S, Liu X, Davis DR, Sigmund CD) Hypertension 2012 Jun;59(6):1212-9       12 Citations
1pitx2 Deficiency results in abnormal ocular and craniofacial development in zebrafish. (Liu Y, Semina EV) PLoS One 2012;7(1):e30896       32 Citations
1Regulation of renin expression by the orphan nuclear receptors Nr2f2 and Nr2f6. (Weatherford ET, Liu X, Sigmund CD) Am J Physiol Renal Physiol 2012 Apr 15;302(8):F1025-33       12 Citations
1Etsrp/Etv2 is directly regulated by Foxc1a/b in the zebrafish angioblast. (Veldman MB, Lin S) Circ Res 2012 Jan 20;110(2):220-9       46 Citations
1Pharmacological and functional genetic assays to manipulate regeneration of the planarian Dugesia japonica. (Chan JD, Marchant JS) J Vis Exp 2011 Aug 31(54)       13 Citations
1IRE1-dependent activation of AMPK in response to nitric oxide. (Meares GP, Hughes KJ, Naatz A, Papa FR, Urano F, Hansen PA, Benveniste EN, Corbett JA) Mol Cell Biol 2011 Nov;31(21):4286-97       71 Citations
1The integrin coactivator kindlin-2 plays a critical role in angiogenesis in mice and zebrafish. (Pluskota E, Dowling JJ, Gordon N, Golden JA, Szpak D, West XZ, Nestor C, Ma YQ, Bialkowska K, Byzova T, Plow EF) Blood 2011 May 05;117(18):4978-87       73 Citations
1Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways. (Zhang H, Rajasekaran NS, Orosz A, Xiao X, Rechsteiner M, Benjamin IJ) J Mol Cell Cardiol 2010 Dec;49(6):918-30       47 Citations
1Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. (Cristea IM, Moorman NJ, Terhune SS, Cuevas CD, O'Keefe ES, Rout MP, Chait BT, Shenk T) J Virol 2010 Aug;84(15):7803-14       144 Citations
1Trans-synaptic EphB2-ephrin-B3 interaction regulates excitatory synapse density by inhibition of postsynaptic MAPK signaling. (McClelland AC, Hruska M, Coenen AJ, Henkemeyer M, Dalva MB) Proc Natl Acad Sci U S A 2010 May 11;107(19):8830-5       64 Citations
1Characterisation of expression patterns and functional role of Cactin in early zebrafish development. (Atzei P, Yang F, Collery R, Kennedy BN, Moynagh PN) Gene Expr Patterns 2010 Jun;10(4-5):199-206       13 Citations
1The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation. (Mangos S, Lam PY, Zhao A, Liu Y, Mudumana S, Vasilyev A, Liu A, Drummond IA) Dis Model Mech 2010;3(5-6):354-65       119 Citations
1Endothelial cell-specific chemotaxis receptor (ecscr) promotes angioblast migration during vasculogenesis and enhances VEGF receptor sensitivity. (Verma A, Bhattacharya R, Remadevi I, Li K, Pramanik K, Samant GV, Horswill M, Chun CZ, Zhao B, Wang E, Miao RQ, Mukhopadhyay D, Ramchandran R, Wilkinson GA) Blood 2010 Jun 03;115(22):4614-22       35 Citations
1Reduced sox9 function promotes heart valve calcification phenotypes in vivo. (Peacock JD, Levay AK, Gillaspie DB, Tao G, Lincoln J) Circ Res 2010 Mar 05;106(4):712-9       112 Citations
1Specific inhibition of cyclin-dependent kinase 5 activity induces motor neuron development in vivo. (Kanungo J, Zheng YL, Amin ND, Kaur S, Ramchandran R, Pant HC) Biochem Biophys Res Commun 2009 Aug 14;386(1):263-7       11 Citations
1Regulation of intracellular cholesterol distribution by Na/K-ATPase. (Chen Y, Cai T, Wang H, Li Z, Loreaux E, Lingrel JB, Xie Z) J Biol Chem 2009 May 29;284(22):14881-90       53 Citations
1Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6. (Wang X, Wang HK, McCoy JP, Banerjee NS, Rader JS, Broker TR, Meyers C, Chow LT, Zheng ZM) RNA 2009 Apr;15(4):637-47       206 Citations
2A mechanosensitive transcriptional mechanism that controls angiogenesis. (Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE) Nature 2009 Feb 26;457(7233):1103-8       473 Citations
1The GABA(A) receptor RDL acts in peptidergic PDF neurons to promote sleep in Drosophila. (Chung BY, Kilman VL, Keath JR, Pitman JL, Allada R) Curr Biol 2009 Mar 10;19(5):386-90       172 Citations
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