| 1 | Local platelet activation causes vasoconstriction of large epicardial canine coronary arteries in vivo. Thromboxane A2 and serotonin are possible mediators. (Golino P, Ashton JH, Buja LM, Rosolowsky M, Taylor AL, McNatt J, Campbell WB, Willerson JT) Circulation 1989 Jan;79(1):154-66 199 Citations |
| 1 | The phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombin. (Si-Tahar M, Renesto P, Falet H, Rendu F, Chignard M) Biochem J 1996 Jan 15;313 ( Pt 2)(Pt 2):401-8 34 Citations |
| 1 | Determination of heparin-induced thrombocytopenia: a rapid flow cytometric assay for direct demonstration of antibody-mediated platelet activation. (Tomer A, Masalunga C, Abshire TC) Am J Hematol 1999 May;61(1):53-61 52 Citations |
| 1 | Calpain controls the balance between protein tyrosine kinase and tyrosine phosphatase activities during platelet activation. (Pain S, Monstero-Lastres A, Falet H, Brohard-Bohn B, Fraiz N, Bachelot-Loza C, Cano E, Rendu F) FEBS Lett 1999 Jun 18;453(1-2):119-23 7 Citations |
| 1 | Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. (Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM) Mol Microbiol 2001 Jan;39(2):330-40 42 Citations |
| 1 | A specific CD36-dependent signaling pathway is required for platelet activation by oxidized low-density lipoprotein. (Chen K, Febbraio M, Li W, Silverstein RL) Circ Res 2008 Jun 20;102(12):1512-9 171 Citations |
| 1 | Type 2 scavenger receptor CD36 in platelet activation: the role of hyperlipemia and oxidative stress. (Silverstein RL) Clin Lipidol 2009 Dec;4(6):767 33 Citations |
| 2 | PECAM-1 functions as a negative regulator of laminin-induced platelet activation. (Crockett J, Newman DK, Newman PJ) J Thromb Haemost 2010 Jul;8(7):1584-93 19 Citations |
| 2 | A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. (Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon AJ, Neubig RR, Newman DK, Stalker TJ, Brass LF) Blood 2012 Feb 23;119(8):1935-45 54 Citations |
| 1 | Polymorphism in the protease-activated receptor-4 gene region associates with platelet activation and perioperative myocardial injury. (Muehlschlegel JD, Perry TE, Liu KY, Fox AA, Smith SA, Lichtner P, Collard CD, Shernan SK, Hartwig JH, Body SC, Hoffmeister KM) Am J Hematol 2012 Feb;87(2):161-6 15 Citations |
| 1 | von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion. (Madabhushi SR, Shang C, Dayananda KM, Rittenhouse-Olson K, Murphy M, Ryan TE, Montgomery RR, Neelamegham S) Blood 2012 May 17;119(20):4769-78 28 Citations |
| 1 | Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions. (Srikanthan S, Li W, Silverstein RL, McIntyre TM) J Thromb Haemost 2014 Nov;12(11):1906-17 119 Citations |
| 1 | An Experimental Model of Platelet Activation at the Feto-Maternal Interface (Arumugam V, An J, Bordas M, Sood R) Blood 124 (21): 2766; https://doi.org/10.1182/blood.V124.21.2766.2766 |
| 4 | Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase. (Zhi H, Dai J, Liu J, Zhu J, Newman DK, Gao C, Newman PJ) PLoS One 2015;10(8):e0135738 32 Citations |
| 3 | A Novel PF4-Dependent Platelet Activation Assay Identifies Patients Likely to Have Heparin-Induced Thrombocytopenia/Thrombosis. (Padmanabhan A, Jones CG, Curtis BR, Bougie DW, Sullivan MJ, Peswani N, McFarland JG, Eastwood D, Wang D, Aster RH) Chest 2016 Sep;150(3):506-15 86 Citations |
| 1 | Metabolic Manipulation to Put the Brakes on Platelet Activation: A Potential Novel Pharmacologic Approach to Atherothrombosis. (Silverstein RL) Arterioscler Thromb Vasc Biol 2016 Oct;36(10):2031-2 |
| 1 | Integrin-αIIbβ3-mediated outside-in signalling activates a negative feedback pathway to suppress platelet activation. (Dai B, Wu P, Xue F, Yang R, Yu Z, Dai K, Ruan C, Liu G, Newman PJ, Gao C) Thromb Haemost 2016 Oct 28;116(5):918-930 15 Citations |
| 1 | Platelet activation and erythrocyte lysis during brief exposure of blood to pathophysiological shear stress in vitro. (Majumdar S, Patil CN, Ladner-Threadgill T, Randolph E, Burgreen GW, Kermode JC) Clin Hemorheol Microcirc 2017;67(2):159-172 7 Citations |
| 1 | Immunopathological response to severe injury: platelet activation and the Th-17 immune response. (Morris RS, Schaffer BS, Lundy JB, Pidcoke HF, Chung KK, Darlington DN, Cap AP, Schwacha MG) Blood Coagul Fibrinolysis 2018 Jan;29(1):48-54 9 Citations |
| 3 | A Platelet Factor 4-Dependent Platelet Activation Assay Facilitates Early Detection of Pathogenic Heparin-Induced Thrombocytopenia Antibodies. (Jones CG, Pechauer SM, Curtis BR, Bougie DW, Irani MS, Dhakal B, Pierce B, Aster RH, Padmanabhan A) Chest 2017 Oct;152(4):e77-e80 19 Citations |
| 1 | The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis. (Branchford BR, Stalker TJ, Law L, Acevedo G, Sather S, Brzezinski C, Wilson KM, Minson K, Lee-Sherick AB, Davizon-Castillo P, Ng C, Zhang W, Neeves KB, Lentz SR, Wang X, Frye SV, Shelton Earp H 3rd, DeRyckere D, Brass LF, Graham DK, Di Paola JA) J Thromb Haemost 2018 Feb;16(2):352-363 27 Citations |
| 2 | Normal plasma IgG inhibits HIT antibody-mediated platelet activation: implications for therapeutic plasma exchange. (Jones CG, Pechauer SM, Curtis BR, Bougie DW, Aster RH, Padmanabhan A) Blood 2018 Feb 08;131(6):703-706 23 Citations |
| 2 | Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation. (Moroi AJ, Zwifelhofer NM, Riese MJ, Newman DK, Newman PJ) Blood Adv 2019 Apr 09;3(7):1154-1166 9 Citations |
| 1 | RGS10 and RGS18 differentially limit platelet activation, promote platelet production, and prolong platelet survival. (DeHelian D, Gupta S, Wu J, Thorsheim C, Estevez B, Cooper M, Litts K, Lee-Sundlov MM, Hoffmeister KM, Poncz M, Ma P, Brass LF) Blood 2020 Oct 08;136(15):1773-1782 21 Citations |
| 1 | Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength. (Jones WL, Ramos CR, Banerjee A, Moore EE, Hansen KC, Coleman JR, Kelher M, Neeves KB, Silliman CC, Di Paola J, Branchford B) Platelets 2022 Nov 17;33(8):1119-1131 18 Citations |
| 1 | Editorial: The immunological role of platelet activation in the pathophysiology of COVID-19. (Rossouw TM, Pretorius E, Wool GD) Front Immunol 2023;14:1285355 |
| 1 | PF4-dependent P-selectin expression assay in comparison to the heparin-induced platelet activation assay for the diagnosis of heparin-induced thrombocytopenia. (Meier RT, Jolink AT, Kempe M, Curtis BR, Hofstede-van Egmond S, de Haas M, Porcelijn L, Kapur R) Transfusion 2025 May;65(5):848-850 |
| 1 | iMer, a naturally occurring MERTK splice variant, binds to GAS6 to decrease platelet activation and thrombus formation (Springborn S, Judd S, Morateck P, VanderZee D, Kidwell A, Brzezinski C, Cox A, Sather S, Neeves KB, DeRyckere D, Di Paola J, Graham DK, Branchford BR) Blood Vessels Thrombosis and Hemostasis August 2025;2(3) |
| 1 | iMer, a naturally occurring MERTK splice variant, binds to GAS6 to decrease platelet activation and thrombus formation. (Springborn S, Judd S, Morateck P, VanderZee D, Kidwell A, Brzezinski C, Cox A, Sather S, Neeves KB, DeRyckere D, Di Paola J, Graham DK, Branchford BR) Blood Vessel Thromb Hemost 2025 Aug;2(3):100078 |
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