Mesh term Signaling Lymphocytic Activation Molecule Family
Browse to parent terms:Membrane Glycoproteins
Receptors, Immunologic
Description
Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation.Browse to child terms:
CD48 Antigen
Signaling Lymphocytic Activation Molecule Family Member 1
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