Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Mesh term Pharmacogenomic Variants

Browse to parent terms:
Polymorphism, Genetic

Description

Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are not markers for GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics and often occur on genes encoding drug metabolism enzymes and transporters (e.g., ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6).



Search for this term in our Faculty Database



View this term at the NCBI website