Mesh term Autophagy-Related Protein-1 Homolog
Browse to parent terms:Autophagy-Related Proteins
Intracellular Signaling Peptides and Proteins
Protein-Serine-Threonine Kinases
Description
A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates.Search for this term in our Faculty Database
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