Medical College of Wisconsin
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Mesh term Chitinase-3-Like Protein 1

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Chitinases
Lectins

Description

A lectin that binds CHITIN, but lacks chitinase activity. It may be involved in tissue remodeling and cellular responses to the environment, including the response of type 2 HELPER T-CELLS to INFLAMMATION and sensitization to ALLERGENS. Mutations in the CHI3L1 gene are associated with ASTHMA.



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