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Mesh term Ku Autoantigen

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Antigens, Nuclear
DNA Helicases
DNA-Binding Proteins
Poly-ADP-Ribose Binding Proteins


An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.

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