Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term MYND Domains

Browse to parent terms:
Protein Interaction Domains and Motifs
Zinc Fingers

Description

Zinc finger domains (named for myeloid, Nervy and DEAF-1) that occur in a variety of eukaryotic proteins, including RUNT-RELATED TRANSCRIPTION FACTOR 1 . They are characterized by a cluster of cysteine and histidine residues with conserved spacing that forms the zinc-binding motif and have beta-beta-alpha (see BETA-SHEET and ALPHA-HELIX) topology, similar to LIM domains (see LIM DOMAIN PROTEINS) and RING FINGER DOMAINS. MYND domains function as protein interaction motifs and have affinity for PROLINE-RICH PROTEIN DOMAINS.



Search for this term in our Faculty Database



View this term at the NCBI website