Mesh term Cisplatin
Browse to parent terms:Chlorine Compounds
Nitrogen Compounds
Platinum Compounds
Description
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.Search for this term in our Faculty Database
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