Mesh term Fibrinogen
Browse to parent terms:Acute-Phase Proteins
Blood Coagulation Factors
Protein Precursors
Description
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.Browse to child terms:
Fibrin Fibrinogen Degradation Products
Fibrinogens, Abnormal
Fibrinopeptide A
Fibrinopeptide B
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