Mesh term Pantothenate Kinase-Associated Neurodegeneration
Browse to parent terms:Basal Ganglia Diseases
Heredodegenerative Disorders, Nervous System
Movement Disorders
Neuroaxonal Dystrophies
Description
A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis and Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)Search for this term in our Faculty Database
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