Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term Pantothenate Kinase-Associated Neurodegeneration

Browse to parent terms:
Basal Ganglia Diseases
Heredodegenerative Disorders, Nervous System
Movement Disorders
Neuroaxonal Dystrophies


A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis and Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)

Search for this term in our Faculty Database

View this term at the NCBI website