Mesh term Immunoglobulins
Browse to parent terms:Immunoproteins
Serum Globulins
Description
Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.Browse to child terms:
Antibodies
Immunoglobulin Constant Regions
Immunoglobulin Fragments
Immunoglobulin Subunits
Immunoglobulin Variable Region
Paraproteins
Receptors, Antigen, B-Cell
gamma-Globulins
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