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Mesh term Leukomalacia, Periventricular

Browse to parent terms:
Cerebrovascular Disorders
Encephalomalacia
Infant, Premature, Diseases

Description

Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)



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jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14