Mesh term Pyrrolizidine Alkaloids
Browse to parent terms:Alkaloids
Heterocyclic Compounds, 2-Ring
Description
A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.Browse to child terms:
Monocrotaline
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