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Mesh term Tissue Distribution

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Pharmacokinetics

Description

Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.



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jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14