Mesh term Trypsin Inhibitor, Kazal Pancreatic
Browse to parent terms:Acute-Phase Proteins
Serine Peptidase Inhibitors, Kazal Type
Description
A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premataure activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS.Search for this term in our Faculty Database
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