Mesh term Wolfram Syndrome
Browse to parent terms:Deaf-Blind Disorders
Diabetes Insipidus
Diabetes Mellitus, Type 1
Optic Atrophies, Hereditary
Description
A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein.Search for this term in our Faculty Database
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