Mesh term Genes, Retinoblastoma
Browse to parent terms:Genes, Tumor Suppressor
Description
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.Search for this term in our Faculty Database
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