Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term DNA Footprinting

Browse to parent terms:
Genetic Techniques

Description

A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)



Search for this term in our Faculty Database



View this term at the NCBI website
jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14