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Mesh term Cytochrome P-450 CYP2E1

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Cytochrome P450 Family 2
Oxidoreductases, N-Demethylating

Description

An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.



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