Mesh term Loss of Heterozygosity
Browse to parent terms:Allelic Imbalance
Description
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.Browse to child terms:
Chromosome Deletion
Haploinsufficiency
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