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Mesh term Miller Fisher Syndrome

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Cerebellar Diseases
Guillain-Barre Syndrome
Ocular Motility Disorders

Description

A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)



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jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a