Mesh term Proto-Oncogene Proteins c-met
Browse to parent terms:Proto-Oncogene Proteins
Receptor Protein-Tyrosine Kinases
Receptors, Growth Factor
Description
Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.Search for this term in our Faculty Database
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