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Mesh term Nuclease Protection Assays

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Genetic Techniques

Description

Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.



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jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14