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Mesh term BRCA2 Protein

Browse to parent terms:
Fanconi Anemia Complementation Group Proteins
Nuclear Proteins
Tumor Suppressor Proteins

Description

A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)



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