Mesh term Heymann Nephritis Antigenic Complex
Browse to parent terms:Autoantigens
Description
A complex of antigenic proteins obtained from the brush border of kidney tubules. It contains two principal components LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2 and LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN. The name of this complex is derived from researcher, Dr. Walter Heymann, who developed an experimental model of membranous glomerulonephritis (GLOMERULONEPHRITIS) by injecting this antigenic complex into rats to induce an autoimmune response.Browse to child terms:
LDL-Receptor Related Protein-Associated Protein
Low Density Lipoprotein Receptor-Related Protein-2
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