Medical College of Wisconsin
CTSIResearch InformaticsREDCap

Mesh term Calreticulin

Browse to parent terms:
Intracellular Calcium-Sensing Proteins
Lectins

Description

A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.



Search for this term in our Faculty Database



View this term at the NCBI website